Phototherapy for neonatal hyperbilirubinaemia: the importance of dose.

Abstract:

:The management of neonatal jaundice can be made much easier using simple methods that increase the radiant energy in the range 420 to 480 nm. Two groups of infants being treated for physiological jaundice during a period of 6 months were compared. The first group received treatment from two unmodified phototherapy units and the second from two units in which the horizontal frames housing the tube lights were lowered, thus providing a higher 'dose' of phototherapy. Measurements of irradiance from the four units were compared. An improvement in treatment was noted in the group receiving the higher dose with a decrease in duration of treatment and a greater rate of fall in the level of serum bilirubin. A dose response relationship was thus confirmed. Comparisons between previous studies are hindered by failure to recognise the varying contribution of background irradiance, the use of radiometers with differing spectral responses, and the use of different units for expressing results. Failure to appreciate the importance of dose must largely be responsible for the present wide variability in the effectiveness of phototherapy.

journal_name

Arch Dis Child

authors

Modi N,Keay AJ

doi

10.1136/adc.58.6.406

subject

Has Abstract

pub_date

1983-06-01 00:00:00

pages

406-9

issue

6

eissn

0003-9888

issn

1468-2044

journal_volume

58

pub_type

杂志文章
  • Is cholecystectomy really an indication for concomitant splenectomy in mild hereditary spherocytosis?

    abstract:BACKGROUND/AIM:The British Committee for Standards in Haematology currently recommends concomitant splenectomy in children with mild hereditary spherocytosis (HS) undergoing cholecystectomy for symptomatic gallstones. However, splenectomy is associated with a risk of life-threatening infection, particularly in young ch...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2009.178228

    authors: Alizai NK,Richards EM,Stringer MD

    更新日期:2010-08-01 00:00:00

  • Ethics support in clinical practice.

    abstract::Ethical considerations have long been a part of clinical decision making. However, just as doctors and healthcare professionals are being increasingly challenged about the evidence base for their practice, there is increasing focus on the ethical dimension of clinical care. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2004.062752

    authors: Watson AR

    更新日期:2005-09-01 00:00:00

  • Hyperammonaemia with distal renal tubular acidosis.

    abstract::The case is reported of an infant with hyperammonaemia secondary to severe distal renal tubular acidosis. A clinical association between increased concentrations of ammonia in serum and renal tubular acidosis has not previously been described. In response to acidosis the infant's kidneys presumably increased ammonia s...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.77.5.441

    authors: Miller SG,Schwartz GJ

    更新日期:1997-11-01 00:00:00

  • Long term behavioural outcome after neonatal arterial switch operation for transposition of the great arteries.

    abstract:AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.87.6.506

    authors: Hövels-Gürich HH,Konrad K,Wiesner M,Minkenberg R,Herpertz-Dahlmann B,Messmer BJ,Von Bernuth G

    更新日期:2002-12-01 00:00:00

  • Sleep-disordered breathing in overweight and obese children and adolescents: prevalence, characteristics and the role of fat distribution.

    abstract:AIMS:To determine the prevalence of sleep-disordered breathing (SDB) in a clinical sample of overweight and obese children and adolescents, and to examine the contribution of fat distribution. METHODS:Consecutive subjects without chronic lung disease, neuromuscular disease, laryngomalacia, or any genetic or craniofaci...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2006.101089

    authors: Verhulst SL,Schrauwen N,Haentjens D,Suys B,Rooman RP,Van Gaal L,De Backer WA,Desager KN

    更新日期:2007-03-01 00:00:00

  • Serum immunoglobulins in multiple pregnancy.

    abstract::The concentrations of immunoglobulins (Ig) G.A.M. and E were determined in paired umbilical cord and maternal sera in 50 twin pregnancies. Mean IgG levels were higher in cord than maternal sera and in most cases the cord IgG level related more closely to that of the other twin than to either maternal level or birthwei...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.51.5.354

    authors: Bryan EM,Slavin B,Nicholson E

    更新日期:1976-05-01 00:00:00

  • Delphi method to identify expert opinion to support children's cancer referral guidelines.

    abstract:BACKGROUND:The National Institute for Health and Care Excellence (NICE) guidance for referral of children with suspected cancer was first published in 2005 and updated in 2015. The updated version relied on sparse primary care evidence and published without input from key stakeholders, for example, acute general paedia...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2019-317235

    authors: Murray MJ,Ruffle A,Lowis S,Howell L,Shanmugavadivel D,Dommett R,Gamble A,Shenton G,Nicholson J

    更新日期:2020-03-01 00:00:00

  • Hereditary multiple glomus tumours.

    abstract::A 9 year old girl presenting with multiple glomus tumours is reported. Multiple glomus tumours are rare, often asymptomatic lesions, with a familial tendency and found in a more proximal location than their solitary counterparts. In our report four close relatives had similar lesions. Indications for surgical excision...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.8.801

    authors: Beasley SW,Mel J,Chow CW,Jones PG

    更新日期:1986-08-01 00:00:00

  • Asthma, wheezing, and school absence in primary schools.

    abstract::The prevalence of wheezing, 'asthma', treatment for 'asthma', and school absence as a result of wheezing in Nottingham was calculated from a questionnaire survey of parents of 4750 children in a random sample of primary schools. A response was achieved for 3805 (80%) children of whom 438 (11.5%) had had episodes of wh...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.2.246

    authors: Hill RA,Standen PJ,Tattersfield AE

    更新日期:1989-02-01 00:00:00

  • "Unresolving pneumonia" as the main manifestation of atypical Kawasaki disease.

    abstract::Two cases of atypical Kawasaki disease (KD) manifested as persistent lobar lung consolidation, prolonged fever, and active inflammatory laboratory markers unresponsive to antibiotic treatment are reported. One of the children developed a giant coronary aneurysm. Atypical KD should be considered in the differential dia...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.88.10.940

    authors: Uziel Y,Hashkes PJ,Kassem E,Gottesman G,Wolach B

    更新日期:2003-10-01 00:00:00

  • Beclomethasone dipropionate aerosol in treatment of hay fever in children.

    abstract::Eighteen children suffering from hay fever were treated with intra-nasal beclomethasone dipropionate (400 mug/day) and an identical placebo aerosol in a double-blind cross-over trial. 17 of the children preferred the intranasal beclomethasone dipropionate, one had no preference, none preferred the placebo. The effect ...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.50.11.875

    authors: Prahl P,Wilken-Jensen K,Mygind N

    更新日期:1975-11-01 00:00:00

  • Protein restriction in chronic renal failure.

    abstract::The aim of the study was to investigate the effect of a protein restricted diet on renal function and growth of children with chronic renal failure. In a multicentre prospective study 56 children (aged 2-18 years) with chronic renal failure were randomly assigned to the protein restricted (0.8-1.1 g/kg/day) or the con...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.68.3.371

    authors: Kist-van Holthe tot Echten JE,Nauta J,Hop WC,de Jong MC,Reitsma-Bierens WC,Ploos van Amstel SL,van Acker KJ,Noordzij CM,Wolff ED

    更新日期:1993-03-01 00:00:00

  • Serum tri-iodothyronine, thyroxine, and thyrotrophin concentrations in newborns during the first 2 days of life.

    abstract::The serum concentrations of tri-iodothyronine (T3), thyroxine (T4), and thyrotrophin (TSH) were measured in 10 term newborn infants between birth and the age of 2 days by radioimmunoassay. The mean concentration of T3 in maternal serum was 1.62 mug/l, and it increased from the low cord blood level of 0-63 mug/l to the...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.50.7.565

    authors: Similä S,Koivisto M,Ranta T,Leppäluoto J,Reinilä M,Haapalahti J

    更新日期:1975-07-01 00:00:00

  • Prophylactic antibiotics in umbilical artery catheterization in the newborn.

    abstract::Over a period of 30 months, umbilical artery catheters were inserted in 229 infants. The main complications were haemorrhage, infection, and obstruction of a blood vessel. The incidence of infection was not affected by the use of prophylactic antibiotics. Vascular obstruction was more common in small infants, and in t...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.48.4.296

    authors: van Vliet PK,Gupta JM

    更新日期:1973-04-01 00:00:00

  • Development of bowel habit in preterm infants.

    abstract::The bowel habits in 844 preterm infants were observed during the first 56 days after birth. Delay in the passage of meconium beyond the second day occurred in 32%, and there was an inverse relation between gestational age and the day of first bowel action. Thereafter the increase in frequency of stools passed each day...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.68.3_spec_no.317

    authors: Weaver LT,Lucas A

    更新日期:1993-03-01 00:00:00

  • Vitamin B12 neuropathy in a 6 year old.

    abstract::Gross neuropathy consequent upon selective malabsorption of vitamin B12 was diagnosed in a 6 year old Bangladeshi girl brought to Great Britain for further investigation of an unexplained illness of three years' duration. The initial peripheral blood count was normal. Treatment with vitamin B12 has led to substantial ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.59.6.575

    authors: Conway SP,Gillies DR,Littlewood JM

    更新日期:1984-06-01 00:00:00

  • Prospective study of serum staphylococcal antibodies in cystic fibrosis.

    abstract::Serum IgG antibodies to teichoic acid and alpha toxin from Staphylococcus aureus were measured in 62 patients with cystic fibrosis by enzyme linked immunosorbent assays. The patients were followed up for 12-24 months in a prospective study. Raised titres were found exclusively in patients chronically colonised with S ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.62.9.905

    authors: Hollsing AE,Granström M,Strandvik B

    更新日期:1987-09-01 00:00:00

  • Stop, think SCORTCH: rethinking the traditional 'TORCH' screen in an era of re-emerging syphilis.

    abstract:BACKGROUND:The epidemiology of congenital infections is ever changing, with a recent resurgence in syphilis infection rates seen in the UK. Identification of congenital infection is often delayed; early recognition and management of congenital infections is important. Testing modalities and investigations are often lim...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/archdischild-2020-318841

    authors: Penner J,Hernstadt H,Burns JE,Randell P,Lyall H

    更新日期:2021-02-01 00:00:00

  • Pharmacological management of abnormal tone and movement in cerebral palsy.

    abstract:BACKGROUND:The evidence base to guide the pharmacological management of tone and abnormal movements in cerebral palsy (CP) is limited, as is an understanding of routine clinical practice in the UK. We aimed to establish details of motor phenotype and current pharmacological management of a representative cohort across ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2018-316309

    authors: Lumsden DE,Crowe B,Basu A,Amin S,Devlin A,DeAlwis Y,Kumar R,Lodh R,Lundy CT,Mordekar SR,Smith M,Cadwgan J

    更新日期:2019-08-01 00:00:00

  • Effect of tracheobronchial suction on respiratory resistance in intubated preterm babies.

    abstract::Measurements of the resistance, time constant, and compliance of the respiratory system were made in 25 mechanically ventilated, preterm babies on 32 occasions, using the single breath technique. Patients were classified according to the level of respiratory resistance by reference to a population of 36 babies studied...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.12.1178

    authors: Prendiville A,Thomson A,Silverman M

    更新日期:1986-12-01 00:00:00

  • Haem arginate in acute hereditary coproporphyria.

    abstract::An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.6.730

    authors: Manning DJ,Gray TA

    更新日期:1991-06-01 00:00:00

  • Nedocromil sodium and exercise induced asthma.

    abstract::Serial exercise tests were carried out by 12 children with asthma on two study days. After a control exercise test either nedocromil sodium 4 mg or placebo were given double blind by metered dose inhaler. Highly significant inhibition of exercise induced asthma occurred after nedocromil, lasting for over two hours. ...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章

    doi:10.1136/adc.62.4.412

    authors: Chudry N,Correa F,Silverman M

    更新日期:1987-04-01 00:00:00

  • Persistence of pneumococcal antibodies after primary immunisation with a polysaccharide-protein conjugate vaccine.

    abstract:INTRODUCTION:Despite immunisation, antibiotics and intensive care management, infection with Streptococcus pneumoniae remains a major cause of morbidity and mortality in children. The WHO currently recommends vaccinating infants with either a 3+0 schedule (6 weeks, 3-4 and 4-6 months of age) or 2+1 schedule (2 doses be...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/archdischild-2018-316254

    authors: Zimmermann P,Perrett KP,Berbers G,Curtis N

    更新日期:2019-07-01 00:00:00

  • Disseminated intravascular clotting in kwashiorkor.

    abstract::The role of disseminated intravascular clotting (DIC) in the pathogenesis of the bleeding diathesis kwashiorkor was investigated in 22 patients. According to the severity of the clinical and haematological findings, two grades of DIC were observed. A severe grade of DIC was shown in 6 cases (5 fatal) presenting with ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.50.4.308

    authors: Hassanein EA,Tankovsky I

    更新日期:1975-04-01 00:00:00

  • Body temperature changes before minor illness in infants.

    abstract::This study aimed to examine the overnight temperature pattern of babies during the prodromal phase of minor illnesses. The overnight rectal temperature pattern of 123 babies was recorded weekly from about 6 to at least 16 weeks old, while parents maintained detailed records of signs of illness. By analysis of patterns...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.71.1.80

    authors: Jackson JA,Petersen SA,Wailoo MP

    更新日期:1994-07-01 00:00:00

  • Hypovitaminosis D among healthy adolescent girls attending an inner city school.

    abstract:AIMS:To determine the prevalence of hypovitaminosis D among healthy adolescent schoolgirls attending an inner city multiethnic girls' school. METHODS:Fifty one (28%) of 182 girls (14 white, 37 non-white; median age 15.3 years, range 14.7-16.6) took part in the study. Biochemical parameters, dietary vitamin D intake, m...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2005.077974

    authors: Das G,Crocombe S,McGrath M,Berry JL,Mughal MZ

    更新日期:2006-07-01 00:00:00

  • Impact of improved glycaemic control on rates of hypoglycaemia in insulin dependent diabetes mellitus.

    abstract::Increased emphasis on strict glycaemic control of insulin dependent diabetes mellitus (IDDM) in young patients may be expected to cause increases in rates of significant hypoglycaemia. To evaluate whether this is the case for a large population based sample of IDDM children and adolescents rates of severe (coma, convu...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.78.2.111

    authors: Davis EA,Keating B,Byrne GC,Russell M,Jones TW

    更新日期:1998-02-01 00:00:00

  • External hydrocephalus and subdural bleeding in infancy associated with transplacental anti-Ro antibodies.

    abstract:BACKGROUND:The isolated finding of an unexplained chronic subdural haematoma in an infant may suggest non-accidental head injury (NAHI). The authors report a previously undescribed cause of multifocal chronic subdural haematoma in infancy which could result in a misdiagnosis of previous NAHI. METHODS:Two infants, aged...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2010.194746

    authors: Edwards RJ,Allport TD,Stoodley NG,O'Callaghan F,Lock RJ,Carter MR,Ramanan AV

    更新日期:2012-04-01 00:00:00

  • Congenital central hypoventilation syndrome. A report of successful experience with bilateral diaphragmatic pacing.

    abstract::Bilateral diaphragmatic pacing was successfully performed in an 18-month-old child with congenital central hypoventilation syndrome (Ondine's curse) as an alternative to long-term mechanical ventilation. Subsequent complications were related more to cor pulmonale and tracheostomy care than to the pacing itself. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.55.11.901

    authors: Coleman M,Boros SJ,Huseby TL,Brennom WS

    更新日期:1980-11-01 00:00:00

  • Comparative growth of primary schoolchildren from one and two parent families.

    abstract::Data drawn from the National Study of Health and Growth enabled an examination to be made of the attained height, weight for height, and triceps skinfold of children from one and two parent families. Children from one parent families were shorter than children from two parent families; however, once heights had been a...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.57.6.453

    authors: Garman AR,Chinn S,Rona RJ

    更新日期:1982-06-01 00:00:00