Abstract:
AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age 7.9-14.3 years by the Child Behaviour Checklist (CBCL) and the Inventory for the Assessment of the Quality of Life in Children and Adolescents (IQCL). RESULTS:Parent reported behavioural outcome on all CBCL problem and competence scores was worse, whereas quality of life on self reported IQCL scores was not reduced compared to the normal population. On multivariate analysis, severe preoperative hypoxia was related to parent reported social problems; peri- and postoperative cardiocirculatory insufficiency was associated with internalizing, externalizing, attention, and total behavioural problems. Reduced expressive language was associated with total behavioural problems, and poor academic achievement was related to parent reported deficits in school performance. Impaired neurological status and reduced endurance capacity both predicted self reported stress by illness. CONCLUSIONS:The neonatal arterial switch operation with combined circulatory arrest and low flow bypass is associated with parent reported long term behavioural impairment, but not with self reported general reduction in quality of life. This discrepancy may be a result of different perception of illness. In our experience, increased risk of long term psychosocial maladjustment after neonatal corrective cardiac surgery is related to the presence of neurological impairment and reduced endurance capacity.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Hövels-Gürich HH,Konrad K,Wiesner M,Minkenberg R,Herpertz-Dahlmann B,Messmer BJ,Von Bernuth Gdoi
10.1136/adc.87.6.506subject
Has Abstractpub_date
2002-12-01 00:00:00pages
506-10issue
6eissn
0003-9888issn
1468-2044journal_volume
87pub_type
杂志文章abstract::Analysis of the response to corticosteroid therapy in a personal series of 8 consecutive cases of dermatomyositis in childhood shows that there are advantages in a moderate dosage, short-term treatment schedule, with gradual tapering of the dosage as soon as there is clinical improvement without waiting for full remis...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.7.494
更新日期:1976-07-01 00:00:00
abstract::National trends in the survival of low birthweight infants for the years 1953 to 1979 were examined. While stillbirth and day 1-28 mortality rates improved steadily throughout this period, day 0 mortality did not start to fall until the mid-1960s and then it improved in all birthweight groups. This suggests that speci...
journal_title:Archives of disease in childhood
pub_type: 历史文章,杂志文章
doi:10.1136/adc.56.2.86
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abstract:BACKGROUND AND AIMS:Data on acute paediatric anaphylaxis presentations to the emergency department (ED) are limited. All allergic presentations to one Australian paediatric ED were studied to determine epidemiological, clinical, and outcome data. METHODS:Retrospective, case based study of patients under 16 years atten...
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.2.186
更新日期:1999-02-01 00:00:00
abstract::Real time ultrasonography of the pelvic organs was performed on 114 normal premenarcheal girls aged between 2 years and 13 years 11 months. Values were obtained for total uterine length, anteroposterior diameters of the corpus and cervix, corpus/cervix ratio, and uterine and ovarian volumes and the resultant data were...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.2.120
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abstract::Two infants presented with a salt-losing syndrome, the presenting features of which were subtle. One case appeared to be transient. Deficient production of aldosterone was shown by plasma renin activity and plasma aldosterone profile. Gas chromatography-mass spectrometry of urine indicated a defect in 18-dehydrogenati...
journal_title:Archives of disease in childhood
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doi:10.1136/adc.52.7.580
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:Heart murmurs are common in children, and they are often referred to a specialist for examination. A clinically innocent murmur does not need further investigation. The referral area of the University Hospital is large and sparsely populated. A new service for remote auscultation (telemedicine) of heart murm...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.87.4.297
更新日期:2002-10-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.9.1086
更新日期:1988-09-01 00:00:00
abstract::Lymphocytes bearing the T cell receptor gamma delta (TCR-gamma delta) were searched for in human early milk lymphocyte suspensions by two colour cytofluorimetric analysis. It was found that the proportion of TCR-gamma delta+ cells was twofold greater in colostrum than in either autologous or heterologous blood samples...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.11.1274-a
更新日期:1990-11-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
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更新日期:2009-08-01 00:00:00
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journal_title:Archives of disease in childhood
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doi:10.1136/adc.66.1.121
更新日期:1991-01-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.4.323
更新日期:1986-04-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:2004-04-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.160325
更新日期:2010-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1136/adc.76.5.432
更新日期:1997-05-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2011-301419
更新日期:2013-02-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,实务指引
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abstract::In 20 children needing treatment for symptomatic sick sinus syndrome, the average age at presentation was 7.1 years and ranged from 9 months to 18 years. Symptoms were never precise but, in retrospect, 5 children had syncope, 7 had a rapid heart action, 6 had dyspnoea or tachypnoea, 2 had nonspecific chest pains, 2 ha...
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doi:10.1136/adc.50.11.879
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更新日期:2019-03-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.8.601
更新日期:1981-08-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
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更新日期:2021-02-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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doi:10.1136/adc.58.8.631
更新日期:1983-08-01 00:00:00
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journal_title:Archives of disease in childhood
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更新日期:1999-07-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.73.3.256
更新日期:1995-09-01 00:00:00
abstract::Plasma testosterone was estimated by radioimmunoassay in 60 children with disorders of sexual development before and after stimulation with human chorionic gonadotrophin (HCG). In 21 children the testosterone levels after 3 and 5 daily injections of 1000 units HCG were compared and good correlation was found between t...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.8.596
更新日期:1976-08-01 00:00:00