Specialist paediatric palliative care services: what are the benefits?

abstract：OBJECTIVE:To determine current use of vitamin K (VK) prophylaxis in newborns and review the efficacy and effectiveness of regimens used. DESIGN:Efficacy and effectiveness calculated using current practice details, data from Southern Ireland and two previous surveys, together with contemporaneous studies of vitamin K d...

journal_title：Archives of disease in childhood

authors： Busfield A,McNinch A,Tripp J

更新日期：2007-09-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：:Glucocorticoid suppressible hyperaldosteronism (GSH) is an uncommon form of dominantly inherited hypertension. Presentation with hypertension and complications such as stroke in early life are well recognised. The use of a simple genetic test carried out on blood or placenta facilitates the detection of infants and ch...

journal_title：Archives of disease in childhood

authors： Jamieson A,Inglis GC,Campbell M,Fraser R,Connell JM

更新日期：1994-07-01 00:00:00

abstract：:The airway response to nebulised ipratropium bromide was studied in 17 chronically or recurrently wheezy infants aged 4-15 months. The peripheral airway response was assessed by the change in maximum flow at functional residual capacity (Vmax FRC) and the upper and central airway response by the change in specific air...

journal_title：Archives of disease in childhood

authors： Prendiville A,Green S,Silverman M

更新日期：1987-04-01 00:00:00

abstract：:Samples of breast milk collected from mothers of infants with breast milk jaundice were analysed for 5 beta-pregnane-3 alpha, 20 beta-diol, and other pregnanediols using gas chromatography-high resolution mass spectrometry. None was detected in any of the specimens and therefore it is unlikely to be the inhibitory fac...

journal_title：Archives of disease in childhood

authors： Murphy JF,Hughes I,Verrier Jones ER,Gaskell S,Pike AW

更新日期：1981-06-01 00:00:00

abstract：:An increased incidence of E. coli sepsis has been observed in neonates given intramuscular iron-dextran for prevention of iron deficiency. Mechanisms for this apparent effect on susceptibility to infection were investigated by comparing phagocytic and antibacterial functions in paired samples of venous blood from 7 in...

journal_title：Archives of disease in childhood

authors： Becroft DM,Dix MR,Farmer K

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Phenobarbital (PB), commonly used as the preferred treatment for neonatal seizure, is a drug that requires careful dose adjustments based on therapeutic drug monitoring. It has been reported that PB metabolism was affected by cytochrome P450 (CYP)2C19 polymorphisms in adults requiring dose adjustment. AIM:T...

journal_title：Archives of disease in childhood

authors： Lee SM,Chung JY,Lee YM,Park MS,Namgung R,Park KI,Lee C

更新日期：2012-06-01 00:00:00

abstract：:A 5-year-old boy with Cockayne's syndrome is described. In addition to the recognised clinical features, he presented with severe fixed airways obstruction, and investigations confirmed clinical and physiological emphysema. In a disorder associated with many of the features of aging, it is probably that the presence o...

journal_title：Archives of disease in childhood

authors： Cunningham M,Godfrey S,Moffat WM

更新日期：1978-09-01 00:00:00

abstract：:The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...

journal_title：Archives of disease in childhood

authors： Sobey G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To investigate whether meningococcal C conjugate vaccine (MCCV) caused relapse in children with steroid-responsive nephrotic syndrome. DESIGN:A population-based study was conducted using an active surveillance system, developed to assess adverse events following vaccination, which linked hospital record inf...

journal_title：Archives of disease in childhood

authors： Taylor B,Andrews N,Stowe J,Hamidi-Manesh L,Miller E

更新日期：2007-10-01 00:00:00

abstract：:We describe the results of a prospective study in which 120 women who developed hypertension in the last trimester of pregnancy were randomly allocated in double blind manner to atenolol or placebo. The mean duration of treatment was five weeks. The only difference between groups during the neonatal period was in resp...

journal_title：Archives of disease in childhood

authors： Reynolds B,Butters L,Evans J,Adams T,Rubin PC

更新日期：1984-11-01 00:00:00

abstract：:A 12 year old Asian girl with a four year history of poorly controlled insulin dependent diabetes mellitus developed overt diabetic nephropathy. There were no clinical features of Rabson-Mendenhall syndrome. Screening for microalbuminuria would have identified incipient diabetic nephropathy and highlighted the importa...

journal_title：Archives of disease in childhood

authors： Francis J,Rose SJ,Raafat F,Milford DV

更新日期：1997-12-01 00:00:00

abstract：:Interstitial nephritis was diagnosed at renal biopsy in 10 previously healthy children. All had identical clinical symptoms: anaemia, raised sedimentation rate, low glomerular filtration rate, protein and leucocytes in the urine, but no bacteria; nine also had glycosuria. Six of the children had a history of recent in...

journal_title：Archives of disease in childhood

authors： Koskimies O,Holmberg C

更新日期：1985-08-01 00:00:00

abstract：:Six families with at least one infant each with confirmed ornithine transcarbamylase deficiency were investigated by DNA analysis. All the affected sons had died, and no DNA had been stored. Using the restriction endonucleases MspI and Bam HI three restriction fragment length polymorphisms were detected which led to e...

journal_title：Archives of disease in childhood

authors： Svirklys LG,Wilcken B,Hammond J,Mackinlay AG,O'Sullivan WJ

更新日期：1988-03-01 00:00:00

abstract：:This pilot study investigated the feasibility of surveying, anonymously, HCV infection among healthy children using an oral fluid specimen. Seventy seven per cent of children provided their assent, or where appropriate, consent to participate; 2.8% were anti-HCV positive. Oral fluid collection is acceptable to childre...

journal_title：Archives of disease in childhood

authors： Chatzipantazi P,Roy KM,Cameron SO,Goldberg D,Welbury R,Bagg J

更新日期：2004-02-01 00:00:00

abstract：:In depth confidential inquiries on all post-perinatal infant deaths were carried out for two years in North and Southern Derbyshire District Health Authorities in order to explore why the postperinatal death rates and cot death rates have been consistently higher in Southern than in North Derbyshire. It was found that...

journal_title：Archives of disease in childhood

authors： Newlands M,Adamson E,Ghulam S,Saleh M,Emery JL

更新日期：1991-12-01 00:00:00

abstract：:Hair growth measurements are a sensitive indicator of nutrition and we have assessed their value in the perinatal period. The proportion of growing roots and their diameter were studied at birth in 114 babies and repeated 3 weeks later in 29 low birthweight babies. Intrauterine malnutrition resulted in thinner roots b...

journal_title：Archives of disease in childhood

authors： Berger HM,King J,Doughty S,Wharton BA

更新日期：1978-04-01 00:00:00

abstract：UNLABELLED:One hundred and seventy three children, including 93 with biliary atresia, received liver grafts at Addenbrooke's Hospital between 1983 and 1993. Of these, only seven developed cyanosis due to intrapulmonary shunting as a complication of their liver disease, and all seven of these had the biliary atresia/pol...

journal_title：Archives of disease in childhood

authors： Fewtrell MS,Noble-Jamieson G,Revell S,Valente J,Friend P,Johnston P,Rasmussen A,Jamieson N,Calne RY,Barnes ND

更新日期：1994-06-01 00:00:00

abstract：:An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...

journal_title：Archives of disease in childhood

authors： Manning DJ,Gray TA

更新日期：1991-06-01 00:00:00

abstract：:We identified 410 infants who were not walking independently by the age of 18 months from among a geographically defined population of 4275 infants who either were born weighing less than 2000 g or had needed admission to the special care nursery in the neonatal period. The outcome of the late walkers was ascertained ...

journal_title：Archives of disease in childhood

authors： Johnson A,Goddard O,Ashurst H

更新日期：1990-05-01 00:00:00

abstract：:Early postnatal malnutrition produces delay in growth and developmental processes, and children from a low socioeconomical level where undernutrition is prevalent are shorter than those from higher socioeconomic levels. We examined the effects of severe and early protein energy malnutrition on growth and bone maturati...

journal_title：Archives of disease in childhood

authors： Alvear J,Artaza C,Vial M,Guerrero S,Muzzo S

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To define better the adult phenotype and natural history of Noonan syndrome. DESIGN:A prospective observational study of a large cohort. RESULTS:Data are presented for 112 individuals with Noonan syndrome (mean age 25.3 (range 12-71) years), who were followed up for a mean of 12.02 years. Mutations in PTPN1...

journal_title：Archives of disease in childhood

authors： Shaw AC,Kalidas K,Crosby AH,Jeffery S,Patton MA

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:To establish the incidence of childhood coeliac disease (CD) in Scotland between 1 September 2009 and 31 August 2010, to determine clinical features at presentation and reasons for diagnosis, and to identify any differences in incidence and practice between regions. DESIGN:Prospective data collection throug...

journal_title：Archives of disease in childhood

authors： White LE,Bannerman E,McGrogan P,Kastner-Cole D,Carnegie E,Gillett PM

更新日期：2013-01-01 00:00:00

abstract：:During the 6-year period from 1 October 1971 to 30 September 1977, 13 (about 1%) of 1225 admissions to hospital with asthma developed severe ventilatory failure (peak arterial PCO 2 greater than 8 kPa). Mean age was 4.1 years (2.3--7.9), and on average each patient had been admitted to hospital on 5 occasions during t...

journal_title：Archives of disease in childhood

authors： Simpson H,Mitchell I,Inglis JM,Grubb DJ

更新日期：1978-09-01 00:00:00

abstract：:Histological examination of the breasts of 26 infants and young children who died suddenly between the ages of 3 weeks and 2 years was performed. The glands were composed of well formed lobules surrounded by dense interlobular stroma, while within the lobules there was looser connective tissue. The lobules contained d...

journal_title：Archives of disease in childhood

authors： McKiernan J,Coyne J,Cahalane S

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Timing of referral to subspecialists may be a major determinant for access to adequate treatment. Kidney transplantation is the preferred modality of renal replacement therapy (RRT) in children. In adults, delayed referral from general physicians to nephrologists reduced access to kidney transplantation. Thi...

journal_title：Archives of disease in childhood

authors： Boehm M,Winkelmayer WC,Arbeiter K,Mueller T,Aufricht C

更新日期：2010-08-01 00:00:00

abstract：:Two cross sectional surveys, 24 years apart, using the same respiratory questionnaire, were carried out to examine changes in prevalence rates of cough, phlegm, and wheeze and to relate changes in wheeze to objective peak expiratory flow rates (PEFRs). The surveys were done in towns in southern and northern England an...

journal_title：Archives of disease in childhood

authors： Whincup PH,Cook DG,Strachan DP,Papacosta O

更新日期：1993-06-01 00:00:00

abstract：:Over a 25 year period, 31 asthmatic children received artificial ventilation for acute asthma at Alder Hey Children's Hospital on 48 occasions. Altogether 47 episodes occurred from 1971-89, with no decline in the number of episodes per year (mean 2.5) over this period. Eight children died during intermittent positive ...

journal_title：Archives of disease in childhood

authors： Seddon PC,Heaf DP

更新日期：1990-12-01 00:00:00

abstract：AIMS:To investigate how parents report children's respiratory sounds on video compared to a clinical "gold standard". METHODS:Five clinicians agreed on 10 video clips of children with audible breathing. These responses were the "gold standard". The clips were shown to parents of children: (a) with asthma/wheeze; (b) w...

journal_title：Archives of disease in childhood

authors： Cane RS,McKenzie SA

更新日期：2001-01-01 00:00:00

abstract：:The concept of neural plasticity and the early natural abilities of hearing children to acquire speech and language without instruction have led many authorities to advocate cochlear implantation before the age of 5 years in congenital deafness. Older children therefore become lower priority for scarce public funds be...

journal_title：Archives of disease in childhood

authors： Gray RF,Jones SE,Court I

更新日期：2003-08-01 00:00:00