Ipratropium bromide and airways function in wheezy infants.

Abstract:

:The airway response to nebulised ipratropium bromide was studied in 17 chronically or recurrently wheezy infants aged 4-15 months. The peripheral airway response was assessed by the change in maximum flow at functional residual capacity (Vmax FRC) and the upper and central airway response by the change in specific airways resistance. The significant reduction in specific airways resistance after treatment with ipratropium bromide signified an improvement in central and upper airway function. No change was found, however, in Vmax FRC and hence in peripheral airway function. It seems that, as in older subjects, inhaled antimuscarinic, anticholinergic drugs have their maximum effect on the large airways, and this may explain their lack of effect in the management of acute bronchiolitis.

journal_name

Arch Dis Child

authors

Prendiville A,Green S,Silverman M

doi

10.1136/adc.62.4.397

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

397-400

issue

4

eissn

0003-9888

issn

1468-2044

journal_volume

62

pub_type

杂志文章
  • Comparison of the use of Tanner and Whitehouse, NCHS, and Cambridge standards in infancy.

    abstract::The British (Tanner and Whitehouse) and American (National Center for Health Statistics, NCHS) growth standards are widely used internationally, although the data are now over 30 years old. Routine weight data was retrieved from the child health records of a complete annual cohort of 3418 children aged 18-30 months to...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.69.4.420

    authors: Wright CM,Waterston A,Aynsley-Green A

    更新日期:1993-10-01 00:00:00

  • Symptoms, atopy, and bronchial response to methacholine in parents with asthma and their children.

    abstract::We have studied 50 children with one parent with asthma at a mean age of 6.4 years by symptom questionnaire and performed allergy skin testing and measurement of bronchial responsiveness to methacholine in both parent and child in 29-32 cases. Ninety eight per cent of the parents were receiving medication for asthma. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.62.1.66

    authors: Clifford RD,Pugsley A,Radford M,Holgate ST

    更新日期:1987-01-01 00:00:00

  • Encephalitis in children.

    abstract::Encephalitis is an uncommon but potentially devastating neurological syndrome with different aetiologies including direct central nervous system infection with different agents (most commonly viral) and those mediated by the immune system. Whilst there have been several recent publications and guidelines on the manage...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/archdischild-2011-300100

    authors: Thompson C,Kneen R,Riordan A,Kelly D,Pollard AJ

    更新日期:2012-02-01 00:00:00

  • Middle aortic syndrome: clinical and radiological findings.

    abstract::Eight patients with the middle aortic syndrome are described. They were aged 2 months to 14 years at diagnosis; follow up was one to 11 years. Clinical presentations included asymptomatic hypertension (n = 5), severe headache, nose bleed, and chest pain (n = 1), and cardiac failure (n = 1). All had severe hypertension...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.4.501

    authors: Sumboonnanonda A,Robinson BL,Gedroyc WM,Saxton HM,Reidy JF,Haycock GB

    更新日期:1992-04-01 00:00:00

  • Lung function, airway responsiveness, and respiratory symptoms before and after bronchiolitis.

    abstract::Acute viral respiratory illness during infancy has been implicated as a precursor for subsequent lower respiratory morbidity in childhood. A prospective, longitudinal study of respiratory function, airway responsiveness, and lower respiratory illness during early childhood was performed in a cohort of 253 healthy infa...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.72.1.16

    authors: Young S,O'Keeffe PT,Arnott J,Landau LI

    更新日期:1995-01-01 00:00:00

  • Prospective surveillance study of medium chain acyl-CoA dehydrogenase deficiency in the UK.

    abstract:BACKGROUND:Medium chain acyl-CoA dehydrogenase (MCAD) deficiency is a common disorder of fatty acid oxidation in north west Europe. It is very variable in its clinical consequences and is believed to be considerably underdiagnosed. OBJECTIVE:To investigate the diagnosis and outcome of MCAD deficiency in the UK. METHO...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.79.2.116

    authors: Pollitt RJ,Leonard JV

    更新日期:1998-08-01 00:00:00

  • Specific malabsorption of vitamin B12 in Down's syndrome.

    abstract::A 3 year old girl with Down's syndrome became lethargic and withdrawn, and investigations showed a specific malabsorption of vitamin B12 without proteinuria. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.5.514

    authors: Cartlidge PH,Curnock DA

    更新日期:1986-05-01 00:00:00

  • Living at high altitude and risk of hospitalisation for atopic asthma in children: results from a large prospective birth-cohort study.

    abstract:BACKGROUND:Asthma is among the most common chronic diseases in childhood and is steadily increasing in prevalence. Better characterisation of factors that determine the risk of hospitalisation for atopic asthma in childhood may help design prevention programmes and improve our understanding of disease pathobiology. Thi...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/adc.2006.106278

    authors: Kiechl-Kohlendorfer U,Horak E,Mueller W,Strobl R,Haberland C,Fink FM,Schwaiger M,Gutenberger KH,Reich H,Meraner D,Kiechl S

    更新日期:2007-04-01 00:00:00

  • Insulin dependent diabetes in under 5 year olds.

    abstract::Insulin dependent diabetes mellitus presenting in children under five years old exhibits several clinical and management features that differ from diabetes presenting in older children. In this review of the current population of the Oxford children's diabetes clinic, children with diabetes diagnosed aged 0- less than...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.60.12.1144

    authors: Jefferson IG,Smith MA,Baum JD

    更新日期:1985-12-01 00:00:00

  • Diagnostic accuracy of chest radiography in detecting mediastinal lymphadenopathy in suspected pulmonary tuberculosis.

    abstract:OBJECTIVE:To estimate the diagnostic accuracy of chest radiography in the detection of chest lymphadenopathy in children with clinically suspected pulmonary tuberculosis. METHODS: DESIGN:Prospective cross sectional study. SETTING:A short stay ward in a children's hospital in South Africa. PATIENTS:Consecutive child...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2004.062315

    authors: Swingler GH,du Toit G,Andronikou S,van der Merwe L,Zar HJ

    更新日期:2005-11-01 00:00:00

  • Diagnostic accuracy of pH monitoring in gastro-oesophageal reflux.

    abstract::One hundred and eleven children admitted with suspected gastro-oesophageal reflux were studied, with 24 hour oesophageal pH monitoring as the first line of investigation. Barium swallow examination, or oesophagoscopy, or both, were carried out only in children with abnormal pH, who subsequently had a trial of 1-12 mon...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.10.1421

    authors: Da Dalt L,Mazzoleni S,Montini G,Donzelli F,Zacchello F

    更新日期:1989-10-01 00:00:00

  • Cortical bone geometry in asthmatic children.

    abstract::At the mid-radius, pre-pubertal asthmatic children had smaller periosteal and endosteal circumferences and thicker cortical shells compared to controls, when assessed by peripheral quantitative computed tomography. Asthmatics had diminished periosteal expansion for muscle size, suggesting that asthma, its treatment, o...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2005.084996

    authors: Quick JL,Ward KA,Adams JE,Mughal MZ

    更新日期:2006-04-01 00:00:00

  • Observational study of two oxygen saturation targets for discharge in bronchiolitis.

    abstract:OBJECTIVES:To assess the potential effect of two guideline discharge oxygen saturation (SpO(2)) recommendations (≥90% and ≥94%) in recovering bronchiolitis. METHODS AND PATIENTS:Infants aged up to 18 months requiring therapeutic oxygen for SpO(2) (≤93%) had SpO(2) assessed in air every 2 h. Time from admission to re-e...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2010.205211

    authors: Cunningham S,McMurray A

    更新日期:2012-04-01 00:00:00

  • Phenotypic variation and detection of carrier status in the partial androgen insensitivity syndrome.

    abstract::The partial androgen insensitivity syndrome occurs in 46,XY subjects with phenotypes ranging from perineoscrotal hypospadias with cryptorchidism and micropenis (mild undervirilisation) to clitoromegaly and partial labial fusion (marked undervirilisation). Within an affected family, wide variation in the degree of geni...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.68.4.453

    authors: Batch JA,Davies HR,Evans BA,Hughes IA,Patterson MN

    更新日期:1993-04-01 00:00:00

  • Measuring compliance with inhaled medication in asthma.

    abstract::Using an electronic inhaler timer device (Nebulizer Chronolog), compliance with the prescribed frequency of inhaled prophylactic medication in 14 asthmatic children was measured. Underuse occurred in 55% of study days while overuse occurred in only 2%. Such devices provide an important new tool for investigating inhal...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.3.332

    authors: Coutts JA,Gibson NA,Paton JY

    更新日期:1992-03-01 00:00:00

  • Socioeconomic disadvantage and onset of childhood chronic disabling conditions: a cohort study.

    abstract:OBJECTIVE:To study the temporal relationship between socioeconomic disadvantage and onset of chronic disabling conditions in childhood. METHOD:Using parent reported data from the Longitudinal Study of Australian Children, we compared children who developed a chronic disabling condition between the ages of 6/7 and 10/1...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2013-305634

    authors: Spencer N,Strazdins L

    更新日期:2015-04-01 00:00:00

  • The sodium and potassium intake of 3 to 5 year olds.

    abstract::The sodium intake of preschool children in their home environment was investigated and the major sources of sodium other than added table salt identified. Thirty five children from a Southampton general practice were studied. Twenty four hour urinary sodium excretion was measured as a reliable indicator of daily total...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.2.159

    authors: Allison ME,Walker V

    更新日期:1986-02-01 00:00:00

  • Acute renal failure in early life.

    abstract::Data are presented on 25 children under 2 years of age with acute renal failure treated by peritoneal dialysis. The clinical features, treatment, complications, and outcome of the illnesses are described. 22 (88%) survived, and though the incidence of serious complications during the illness was high most regained ful...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.51.6.459

    authors: Griffin NK,McElnea J,Barratt M

    更新日期:1976-06-01 00:00:00

  • Subclinical hypothyroidism and Down's syndrome; studies on myocardial structure and function.

    abstract:BACKGROUND:The management of subclinical hypothyroidism (SH) is still controversial, as the benefit to risk ratio of prolonged L-thyroxine therapy is not clear cut. Some authors have shown abnormalities of myocardial function and structure in adults with SH, which could be reversed by L-thyroxine therapy. As SH frequen...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.88.11.1005

    authors: Toscano E,Pacileo G,Limongelli G,Verrengia M,Di Mita O,Di Maio S,Salerno M,Del Giudice E,Caniello B,Calabrò R,Andria G

    更新日期:2003-11-01 00:00:00

  • Invasion by human herpesvirus 6 and human herpesvirus 7 of the central nervous system in patients with neurological signs and symptoms.

    abstract:METHODS:A total of 43 children with neurological signs and symptoms were enrolled in the study. All children were suspected of having meningitis, and lumbar punctures were performed. Human herpesvirus 6 (HHV-6) and HHV-7 DNA was detected in cerebrospinal fluid (CSF) and peripheral blood mononuclear cells (PBMC) by nest...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.83.2.170

    authors: Yoshikawa T,Ihira M,Suzuki K,Suga S,Matsubara T,Furukawa S,Asano Y

    更新日期:2000-08-01 00:00:00

  • Persistent neonatal hypoglycaemia due to glucagon deficiency.

    abstract::In a newborn baby, suffering from persistent severe hypoglycaemia with convulsions glucagon deficiency was shown. Treatment with zinc-protamine-glucagon injection twice daily resulted in normal blood glucose levels. Motor development is delayed. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.53.5.422

    authors: Kollee LA,Monnens LA,Cecjka V,Wilms RM

    更新日期:1978-05-01 00:00:00

  • Why do children hospitalised with pneumonia not receive antibiotics in primary care?

    abstract:BACKGROUND:Although antibiotics are recommended for the primary care management of community-acquired pneumonia, a recent UK study reported that most children admitted to hospital had not received antibiotics. OBJECTIVE:To describe primary care antibiotic use for children subsequently hospitalised with community-acqui...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2011-300604

    authors: Grant CC,Harnden A,Mant D,Emery D,Coster G

    更新日期:2012-01-01 00:00:00

  • Singapore Undiagnosed Disease Program: Genomic Analysis aids Diagnosis and Clinical Management.

    abstract:OBJECTIVE:Use next-generation sequencing (NGS) technology to improve our diagnostic yield in patients with suspected genetic disorders in the Asian setting. DESIGN:A diagnostic study conducted between 2014 and 2019 (and ongoing) under the Singapore Undiagnosed Disease Program. Date of last analysis was 1 July 2019. S...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2020-319180

    authors: Bhatia NS,Lim JY,Bonnard C,Kuan JL,Brett M,Wei H,Cham B,Chin H,Bosso-Lefevre C,Dharuman P,Escande-Beillard N,Devasia AG,Goh CYJ,Kam S,Liew WK,Liew WK,Lin G,Jain K,Ng AY,Subramanian D,Xie M,Tan YM,Tawari NR,T

    更新日期:2021-01-01 00:00:00

  • Streptokinase for aortic thrombosis.

    abstract::A neonate developed complete thrombosis of the abdominal aorta after catheterisation of the umbilical artery. This was successfully treated with an intravenous infusion of streptokinase. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.63.9.1086

    authors: Kirk CR,Bhrolchain CN,Qureshi SA

    更新日期:1988-09-01 00:00:00

  • Early excessive growth with distinct seasonality in preschool obesity.

    abstract:OBJECTIVES:Healthy-weight children tend to gain weight during winter but lose weight during summer. However, overweight elementary school children have shown accelerated summertime weight gain. Whether this seasonal growth variation occurs during preschool period is of substantial interest. METHODS:Data were derived f...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2018-314862

    authors: Isojima T,Kato N,Yokoya S,Ono A,Tanaka T,Yokomichi H,Yamagata Z,Tanaka S,Matsubara H,Ishikuro M,Kikuya M,Chida S,Hosoya M,Kuriyama S,Kure S

    更新日期:2019-01-01 00:00:00

  • Alteration of lung diffusion capacity in IgA nephropathy.

    abstract:OBJECTIVE:To establish whether changes of lung transfer for carbon monoxide (TLCO) are related to the phase of IgA nephropathy. METHODS:Respiratory function was tested in 12 children with IgA nephropathy assessed by percutaneous renal biopsy. This was done during acute exacerbations or haematuria-free phases of the di...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章

    doi:10.1136/adc.74.3.236

    authors: Ravilly S,Chaussain M,Iniguez JL,Lenhert A,Kalifa G,Brun P,Niaudet P,Gendrel D

    更新日期:1996-03-01 00:00:00

  • Frequency of transient hypothyroxinaemia in low birthweight infants. Potential pitfall for neonatal screening programmes.

    abstract::Thyroid function was studied in 54 low birthweight infants during a 3-week period. Each infant was placed in one of three groups. Group 1 (n = 21), infants who were well and appropriately grown fro gestational age; group 2 (n = 23), infants who were appropriately grown but who had hyaline membrane disease; group 3 (n ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.56.3.214

    authors: Uhrmann S,Marks KH,Maisels MJ,Kulin HE,Kaplan M,Utiger R

    更新日期:1981-03-01 00:00:00

  • Higher rectal temperatures in co-sleeping infants.

    abstract::The effect on deep body temperature of infants co-sleeping (with either or both parents) is investigated in this case control study. Overnight continuous recordings of rectal temperature were made from 34 babies co-sleeping with one or both parents throughout the night and 34 infants matched for age, feeding regimen, ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.75.3.249

    authors: Tuffnell CS,Petersen SA,Wailoo MP

    更新日期:1996-09-01 00:00:00

  • Plethysmographic validation of near infrared spectroscopic monitoring of cerebral blood volume.

    abstract::The validation of measurement of cerebral blood volume (CBV) and cerebral blood flow (CBF) using near infrared spectroscopy (NIRS) against jugular venous occlusion plethysmography is described. Repeated measurements in six infants were made using both techniques simultaneously. A close relationship between the two mea...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.67.4_spec_no.407

    authors: Wickramasinghe YA,Livera LN,Spencer SA,Rolfe P,Thorniley MS

    更新日期:1992-04-01 00:00:00

  • Parental restriction reduces the harmful effects of in-bedroom electronic devices.

    abstract:OBJECTIVE:To investigate whether school readiness could be affected by placing electronic devices (EDs) in children's bedroom and whether the relationship was moderated by parental restriction and family socioeconomic status (SES). DESIGN:This is a cross-sectional study with bedroom ED placement and parental restricti...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2017-312639

    authors: Fu KW,Ho FKW,Rao N,Jiang F,Li SL,Lee TM,Chan SH,Yung AW,Young ME,Ip P

    更新日期:2017-12-01 00:00:00