Abstract:
:Eight patients with the middle aortic syndrome are described. They were aged 2 months to 14 years at diagnosis; follow up was one to 11 years. Clinical presentations included asymptomatic hypertension (n = 5), severe headache, nose bleed, and chest pain (n = 1), and cardiac failure (n = 1). All had severe hypertension requiring multiple drug treatment. Diminished peripheral pulses were not helpful in the diagnosis, which is made on aortography. Associated clinical findings were Williams' syndrome (n = 3) and appreciable eosinophilia (n = 3). The differential diagnosis includes Takayasu's arteritis, fibromuscular dysplasia, and neurofibromatosis. Blood pressure was adequately controlled by medical treatment in six patients. Surgical angioplasty was performed in two. One patient remained normotensive without drug treatment 21 months after operation; the other died of sepsis and uncontrollable haemorrhage in the postoperative period. Medical treatment is satisfactory in most cases: surgery should be reserved for those in whom blood pressure cannot be controlled without unacceptable side effects of drug treatment. Although rare, the middle aortic syndrome should be considered in the differential diagnosis of hypertension when commoner causes have been excluded. Aortography is necessary for diagnosis.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Sumboonnanonda A,Robinson BL,Gedroyc WM,Saxton HM,Reidy JF,Haycock GBdoi
10.1136/adc.67.4.501subject
Has Abstractpub_date
1992-04-01 00:00:00pages
501-5issue
4eissn
0003-9888issn
1468-2044journal_volume
67pub_type
杂志文章abstract::Seventy infants with suspected bacterial infection in the first 48 hours of life were treated either with piperacillin and flucloxacillin or with penicillin and gentamicin. Infection was confirmed and successfully eradicated in 6 of the 35 infants receiving piperacillin and flucloxacillin. Four infants treated with pe...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.58.12.1006
更新日期:1983-12-01 00:00:00
abstract:AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.87.6.506
更新日期:2002-12-01 00:00:00
abstract::Concerns have been expressed in recent years about the decline in children's clinical and biomedical research in the UK, and in the paediatric academic workforce. Here I consider the extent to which these concerns are justified, the sweeping changes that have taken place in research funding, governance and organisatio...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.178160
更新日期:2010-11-01 00:00:00
abstract::Human immunodeficiency virus (HIV) related cancers in children are not as common and as well described as in adults. An HIV epidemic has been prevalent in Zambia since 1983-1984. To study the effect of the epidemic on the epidemiology of cancers in children a retrospective study was undertaken at the University Teachi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.73.2.100
更新日期:1995-08-01 00:00:00
abstract:AIM:To produce a growth reference for British children with Williams syndrome. METHODS:The children and adults recruited into the study were all affiliated to the Williams Syndrome Foundation, a parent support group founded in 1979. They have all been shown to have a deletion of chromosome 7q11.23. One growth nurse (W...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2006.107946
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Mauriac syndrome is characterised by growth failure, cushingoid appearance and hepatomegaly which occurs in patients with insulin dependent diabetes and was first described shortly after the introduction of insulin as a treatment for the condition. OBJECTIVE:To describe the clinical features, histological f...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2013-304426
更新日期:2014-04-01 00:00:00
abstract::Lung function measurements with and without a disposable bacterial filter were compared in 60 children. Although statistically significant, the reduction of lung function measurements caused by using bacterial filters was small and clinically irrelevant (2-4% of predicted for forced expiratory volume in one second and...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.85.4.346
更新日期:2001-10-01 00:00:00
abstract::Immunohistochemical studies of pancreatic tissue from patients with cystic fibrosis associated with diabetes mellitus (CFDM) show increased numbers of somatostatin secreting delta cells. To look for a possible functional correlate to this finding basal and arginine stimulated plasma somatostatin and serum C peptide co...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.1.123
更新日期:1993-01-01 00:00:00
abstract:AIM:To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. METHODS:A national prospective population-based cohort study over 25 months. Newly diagnosed PTCS cases notified via British Paediatric Surveillance Unit were ascertained using cla...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2016-312238
更新日期:2017-08-01 00:00:00
abstract::We studied 91 offspring of ABO incompatible preganacies and 30 controls resulting from O--O pregnancies to test whether cord bilirubin levels could be used to predict the severity of hyperbilirubinaemia in ABO incompatibility. Blood group, direct Coombs's test, and serum bilirubin estimations were carried out on cord ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.3.219
更新日期:1977-03-01 00:00:00
abstract:AIM:To evaluate the risk factors for breakthrough varicella in a follow up study of a cohort of 181 healthy children immunised when aged 9-24 months with a reformulated Oka strain varicella vaccine (SmithKline Beecham Biologicals/Oka). DESIGN:The children were randomised in a double blind manner into one of four group...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.79.6.478
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:The passage of hard stools is significantly more common in formula fed infants than breast fed infants and this might be the result of differences in fat absorption between breast and formula fed infants. Experimental studies indicate that long chain polyunsaturated fatty acids (LCPUFAs) might influence fat ...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.81.3.253
更新日期:1999-09-01 00:00:00
abstract::Eighty-two cases of protracted diarrhoea in infancy presenting over a 6-year period have been analysed, with particular reference to diagnosis and management. The patients fell into 1 of 2 categories according to whether a specific diagnosis was established or not. A diagnosis (category 1) was established in 59 (72%),...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.8.597
更新日期:1977-08-01 00:00:00
abstract:OBJECTIVE:Anaphylaxis is a severe, potentially fatal allergic reaction best treated with intramuscular epinephrine via epinephrine auto-injectors (AAIs). Our published concerns over laceration injuries to young children associated with AAIs led to this service evaluation of the two administration methods: swing and jab...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2020-318898
更新日期:2021-01-01 00:00:00
abstract:AIMS:To determine the prevalence of sleep-disordered breathing (SDB) in a clinical sample of overweight and obese children and adolescents, and to examine the contribution of fat distribution. METHODS:Consecutive subjects without chronic lung disease, neuromuscular disease, laryngomalacia, or any genetic or craniofaci...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2006.101089
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To undertake a systematic review and meta-analysis to establish the effectiveness of handwashing in reducing absence and/or the spread of respiratory tract (RT) and/or gastrointestinal (GI) infection among school-aged children and/or staff in educational settings. DESIGN:Randomised-controlled trials (RCTs). ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,meta分析,评审
doi:10.1136/archdischild-2015-308875
更新日期:2016-01-01 00:00:00
abstract::Th incidence and severity of posterior subcapsular cataracts were studied in 58 children with steroid-sensitive nephrotic syndrome. Eight (14%) children had cataracts. Visual acuity was normal in all but one child. There was no relationship between total dose or mean daily dose of prednisolone (corrected for body surf...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:The value of comparative effectiveness trials in informing clinical and policy decisions depends heavily on the choice of control arm (comparator). Our objective is to identify challenges in comparator reasoning and to determine justification criteria for selecting a control arm in paediatric clinical trials....
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2016-310644
更新日期:2016-10-01 00:00:00
abstract::Concentrations of chorionic somatomammotrophin (hCS) in maternal plasma at the time of delivery and in placental extracts were determined by radioimmunoassay and related to neonatal growth in 111 normal pregnancies. Mean maternal plasma hCS concentration was lower in association with small-for-dates infants, defined b...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.2.120
更新日期:1976-02-01 00:00:00
abstract:AIMS:To determine whether the use of negative pressure ventilation (NPV) was associated with a lower rate of endotracheal intubation in infants with recurrent apnoea secondary to acute bronchiolitis. METHODS:Retrospective review of two paediatric intensive care units (PICU) databases and case notes; one PICU offered N...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2003.039404
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To investigate gastric emptying and intestinal transit of pelleted pancreatin in relation to food boluses. METHODS:Dual isotope scintigraphy combined with breath hydrogen sampling was used to track the concurrent gastric emptying and intestinal transit of 111indium labelled microspheres and a 99mtechnetium l...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.2.149
更新日期:1999-02-01 00:00:00
abstract::Two hundred and twenty eight deprived children were compared with a matched sample of more endowed children living in the same urban area. Both groups were served by the same experienced primary health care team. The deprived group had a significantly higher number of general practitioner consultations and admissions ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.4.392
更新日期:1987-04-01 00:00:00
abstract::The objectives of this study were to determine whether or not the probiotic Lactobacillus GG can colonise the immature bowel of premature infants and if so, does colonisation result in a reduction of the size of the bowel reservoir of nosocomial pathogens such as enterobacteriaceae, enterococci, yeasts or staphylococc...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.69.5_spec_no.483
更新日期:1993-11-01 00:00:00
abstract::The first case of collagenous colitis in a child with protracted watery diarrhoea and abdominal pain is reported. Small bowel investigations and the macroscopic appearances were normal, but histological examination of the colon showed collagenous colitis. Steroids temporarily relieved the diarrhoea and induced transie...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.64.6.867
更新日期:1989-06-01 00:00:00
abstract::Four children, including three infants, who died suddenly and unexpectedly are described. In three of the cases group A beta haemolytic streptococcus was cultured and in the fourth Streptococcus pneumoniae. The organism was grown from multiple sites including blood in two of them. Without microbiological investigation...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.69.3.381
更新日期:1993-09-01 00:00:00
abstract::The neurodevelopmental state of 41 children with congenital cytomegalovirus infection and their controls was assessed at 2 years using the Griffiths scale. The scores achieved by children with congenital cytomegalovirus but with no associated neurological abnormality (asymptomatic) were similar to those of the control...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.4.323
更新日期:1986-04-01 00:00:00
abstract::Aortic arch anomalies in infancy often cause intrathoracic airway obstruction. Airway function was assessed as part of the diagnostic evaluation in six symptomatic infants both by plethysmography and using a chest compression technique to obtain partial flow-volume loops. Two infants had normal intrathoracic airway fu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.2.171
更新日期:1990-02-01 00:00:00
abstract::Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章
doi:10.1136/adc.55.3.171
更新日期:1980-03-01 00:00:00
abstract:OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,随机对照试验
doi:10.1136/adc.2008.145664
更新日期:2009-05-01 00:00:00
abstract:AIMS:To prospectively evaluate sinopulmonary disease in 24 patients with primary humoral immunodeficiency (11 with agammaglobulinaemia, nine with isolated IgA deficiency, and two with common variable immunodeficiency) and chronic productive cough, ascertain the usefulness of chest high resolution computed tomography (H...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.12.1101
更新日期:2003-12-01 00:00:00