A randomised controlled study of the effect of long chain polyunsaturated fatty acid supplementation on stool hardness during formula feeding.

Abstract:

BACKGROUND:The passage of hard stools is significantly more common in formula fed infants than breast fed infants and this might be the result of differences in fat absorption between breast and formula fed infants. Experimental studies indicate that long chain polyunsaturated fatty acids (LCPUFAs) might influence fat hydrolysis and absorption. AIM:To investigate the relation of LCPUFA supplementation to stool frequency and consistency during the first 4 months of life. DESIGN:Double blind, randomised, controlled study of 88 healthy infants. RESULTS:1905 stools (858 from LCPUFA supplemented infants, 1047 non-supplemented infants) were examined. The mean (SEM) number of stools passed for each three day study period was significantly less in the LCPUFA group (5.5 (0.3) v 6.2 (0.2); p < 0.05). In both groups, there was a significant reduction in the number of stools passed with age (p < 0.001). During the first 3 months, the mean (SEM) percentage of hard stools passed by infants in the LCPUFA supplemented group was 7.7 (2.1) compared with 19.2 (2.8) for unsupplemented infants (p = 0.001). CONCLUSION:The prevalence of hard stools is significantly reduced in infants fed a formula that is supplemented with LCPUFAs.

journal_name

Arch Dis Child

authors

Forsyth JS,Varma S,Colvin M

doi

10.1136/adc.81.3.253

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

253-6

issue

3

eissn

0003-9888

issn

1468-2044

journal_volume

81

pub_type

临床试验,杂志文章,随机对照试验
  • Raised intracranial pressure not detected by ultrasound.

    abstract::Two patients with raised intracranial pressure responding to ventriculoperitoneal shunting are described in whom ultrasound failed to show dilated ventricles. The importance of not equating absence of ventricular dilatation with normal pressure and ventricular dilatation with high pressure is emphasised. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.60.6.581

    authors: Pilling DW,Cudmore RE

    更新日期:1985-06-01 00:00:00

  • Survival after balloon atrial septostomy for complete transposition of great arteries.

    abstract::Mortality before surgery must be taken into account when comparing the surgical mortality of atrial redirection procedures (Mustard's or Senning's operation) and the arterial switch operation for patients with complete transposition. This is because the switch operation is usually performed within the neonatal period ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.62.6.549

    authors: Mok Q,Darvell F,Mattos S,Smith T,Fayers P,Rigby ML,Shinebourne EA

    更新日期:1987-06-01 00:00:00

  • Independent risk factors for chronic cyclosporine induced nephropathy in children with nephrotic syndrome.

    abstract:BACKGROUND:Cyclosporine A (CsA) has been widely used in children with steroid dependent and steroid resistant nephrotic syndrome (NS) because of its efficacy in relieving these patients from systemic side effects of steroids. However, its long term use is controversial, since chronic CsA induced nephropathy (CsAN) may ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2005.080960

    authors: Fujinaga S,Kaneko K,Muto T,Ohtomo Y,Murakami H,Yamashiro Y

    更新日期:2006-08-01 00:00:00

  • Superhero-related injuries in paediatrics: a case series.

    abstract::Five cases of serious injuries to children wearing superhero costumes, involving extreme risk-taking behaviour, are presented here. Although children have always displayed behaviour seemingly unwise to the adult eye, the advent of superhero role models can give unrealistic expectations to the child, which may lead to ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2006.109793

    authors: Davies P,Surridge J,Hole L,Munro-Davies L

    更新日期:2007-03-01 00:00:00

  • Parental recall of birth weight: how accurate is it?

    abstract:OBJECTIVE:To assess the accuracy of parental recall of birth weight in a British population and to investigate whether social class and age of the child significantly influence the accuracy of recalled birth weight. METHODS:A questionnaire was given to parents whose children were participating in a blood pressure stud...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.82.3.202

    authors: O'Sullivan JJ,Pearce MS,Parker L

    更新日期:2000-03-01 00:00:00

  • Photopheresis at onset of type 1 diabetes: a randomised, double blind, placebo controlled trial.

    abstract:BACKGROUND:In recent years photopheresis, an extracorporeal form of photochemotherapy using psoralen and ultraviolet A irradiation of leucocytes, has been claimed to be an effective form of immunomodulation. AIM:To evaluate its effect in type 1 diabetes we performed a double blind, controlled study using placebo table...

    journal_title:Archives of disease in childhood

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/adc.85.2.149

    authors: Ludvigsson J,Samuelsson U,Ernerudh J,Johansson C,Stenhammar L,Berlin G

    更新日期:2001-08-01 00:00:00

  • Invasive meningococcal disease in children in Ireland, 2001-2011.

    abstract:BACKGROUND:In 1999, invasive meningococcal disease was hyperendemic in Ireland at 14.75/100 000 population, with 60% group B and 30% group C diseases. National sepsis guidelines and meningococcal C vaccines were introduced in 2000. Despite a spontaneous decline in group B infection, invasive meningococcal disease remai...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/archdischild-2015-310215

    authors: Ó Maoldomhnaigh C,Drew RJ,Gavin P,Cafferkey M,Butler KM

    更新日期:2016-12-01 00:00:00

  • Otoacoustic emissions and auditory brainstem responses in the newborn.

    abstract::The auditory function of 370 infants, drawn from both low and high risk groups, was tested before postnatal discharge using three tests: standard auditory brain stem responses (ABR), automated analysis of ABR, and automated analysis of evoked otoacoustic emissions (OAE). All infants failing any neonatal test had furth...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.10_spec_no.1124

    authors: Kennedy CR,Kimm L,Dees DC,Evans PI,Hunter M,Lenton S,Thornton RD

    更新日期:1991-10-01 00:00:00

  • Doppler analysis of superior mesenteric artery blood flow in preterm infants.

    abstract::Transcutaneous Doppler ultrasound measurements were made of the superior mesenteric artery of 22 preterm infants (mean birth weight 600-2580 g) to investigate the response of intestinal blood flow to feeding. Analysis of the data in relation to milk intake showed a significant change in peak velocity and mean velocity...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.64.4_spec_no.476

    authors: Leidig E

    更新日期:1989-04-01 00:00:00

  • Delayed gastric emptying: a novel gastrointestinal finding in Turner's syndrome.

    abstract:AIM:To evaluate gastric emptying in girls with Turner's syndrome to detect if gastrointestinal motor dysfunction was present. SUBJECTS:Thirteen girls (mean age 8.1 years) with Turner's syndrome, seven girls with familial short stature (6.1 years), and eight control girls (7.6 years). METHODS:Gastric emptying studies ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.75.5.440

    authors: Staiano A,Salerno M,Di Maio S,Marsullo G,Marino A,Concolino D,Strisciuglio P

    更新日期:1996-11-01 00:00:00

  • Mortality from 1 to 16-18 years in bilateral cerebral palsy.

    abstract:OBJECTIVE:To ascertain mortality from 1 to 18 years, and predictors of mortality. DESIGN:Long-term follow-up of population cohort born 1989-1992. SETTING:Births in South East Thames Region. PATIENTS:346 children with bilateral cerebral palsy (CP). INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Mortality; pred...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2009.172841

    authors: Baird G,Allen E,Scrutton D,Knight A,McNee A,Will E,Elbourne D

    更新日期:2011-11-01 00:00:00

  • Named/designated doctor status and judgement in child-protection scenarios.

    abstract::Four child-protection scenarios were sent to 200 named/designated and non-named/non-designated doctors. The respondents judged each scenario as abuse or accident and indicated their degree of certainty. There was a 71% response rate. There were no significant differences in judgement or degrees of certainty of judgeme...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.2006.105528

    authors: Power S

    更新日期:2008-07-01 00:00:00

  • Copper deficiency in the preterm infant of very low birthweight. Four cases and a reference range for plasma copper.

    abstract::Four preterm infants of very low birthweight (less than 1500 g) developed signs of copper deficiency between age 8 and 10 weeks. All had required prolonged ventilatory support, parenteral nutrition, and nasojejunal feeding. The clinical features, which included osteoporosis, oedema, anaemia, neutropenia, and late apno...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.60.7.644

    authors: Sutton AM,Harvie A,Cockburn F,Farquharson J,Logan RW

    更新日期:1985-07-01 00:00:00

  • A new paradigm for developing drugs in children: atomoxetine as a model.

    abstract::When prescribing drugs for children, it is fundamental to acknowledge that they are distinct from adults with a different physiology and metabolism. They are also still maturing. The development of drugs with a primarily paediatric indication thus requires the trialling of these drugs in a paediatric population to ass...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2004.059378

    authors: Prasad S

    更新日期:2005-02-01 00:00:00

  • Physical growth and bone age of survivors of protein energy malnutrition.

    abstract::Early postnatal malnutrition produces delay in growth and developmental processes, and children from a low socioeconomical level where undernutrition is prevalent are shorter than those from higher socioeconomic levels. We examined the effects of severe and early protein energy malnutrition on growth and bone maturati...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.3.257

    authors: Alvear J,Artaza C,Vial M,Guerrero S,Muzzo S

    更新日期:1986-03-01 00:00:00

  • Pseudotumor cerebri syndrome in childhood: incidence, clinical profile and risk factors in a national prospective population-based cohort study.

    abstract:AIM:To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. METHODS:A national prospective population-based cohort study over 25 months. Newly diagnosed PTCS cases notified via British Paediatric Surveillance Unit were ascertained using cla...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2016-312238

    authors: Matthews YY,Dean F,Lim MJ,Mclachlan K,Rigby AS,Solanki GA,White CP,Whitehouse WP,Kennedy CR

    更新日期:2017-08-01 00:00:00

  • HCG stimulation test in children with abnormal sexual development.

    abstract::Plasma testosterone was estimated by radioimmunoassay in 60 children with disorders of sexual development before and after stimulation with human chorionic gonadotrophin (HCG). In 21 children the testosterone levels after 3 and 5 daily injections of 1000 units HCG were compared and good correlation was found between t...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.51.8.596

    authors: Grant DB,Laurance BM,Atherden SM,Ryness J

    更新日期:1976-08-01 00:00:00

  • Procedures, placement, and risks of further abuse after Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation.

    abstract:OBJECTIVES:To investigate outcome, management, and prevention in Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation. DESIGN:Ascertainment through British Paediatric Surveillance Unit and questionnaires to responding paediatricians. SETTING:The UK and Republic of Ireland, September ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,多中心研究

    doi:10.1136/adc.78.3.217

    authors: Davis P,McClure RJ,Rolfe K,Chessman N,Pearson S,Sibert JR,Meadow R

    更新日期:1998-03-01 00:00:00

  • Infantile acute liver failure in the West of Scotland.

    abstract:BACKGROUND:Our current understanding regarding the aetiology of infantile acute liver failure largely derives from studies conducted by regional liver units. This may introduce selection bias and therefore not provide a true reflection of the wider population. METHODS:Every coagulation screen with a prothrombin time ≥...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2019-317360

    authors: Wands D,Tayler R,Kelly D,Pinto F,Simpson JH,Hansen R

    更新日期:2020-08-01 00:00:00

  • Functional outcomes in children with anatomically repaired transposition of the great arteries with regard to congenital ventricular septal defect and coronary pattern.

    abstract:OBJECTIVE:Despite decreasing mortality, functional impairments in children with transposition of the great arteries (TGA) are still a concern. This study analyses health-related physical fitness (HRPF), arterial stiffness and health-related quality of life (HRQoL) in children with anatomically repaired TGA regarding co...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2018-316444

    authors: Häcker AL,Reiner B,Oberhoffer R,Hager A,Ewert P,Müller J

    更新日期:2019-09-01 00:00:00

  • Respiratory viruses in exacerbations of non-cystic fibrosis bronchiectasis in children.

    abstract:BACKGROUND:Respiratory viral infections precipitate exacerbations of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease though similar data in non-cystic fibrosis (CF) bronchiectasis are missing. Our study aimed to determine the point prevalence of viruses associated with exacerbation...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/archdischild-2013-305147

    authors: Kapur N,Mackay IM,Sloots TP,Masters IB,Chang AB

    更新日期:2014-08-01 00:00:00

  • Impact of HIV-1 infection in South Africa.

    abstract::In a prospective study, 60% of admissions to an academic hospital were infected with HIV. HIV infected children were younger, less likely to have been referred, more likely to have pneumonia and candidiasis, and had more health service attendances. This impact may be alleviated by appropriate primary and secondary lev...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.85.1.50

    authors: Pillay K,Colvin M,Williams R,Coovadia HM

    更新日期:2001-07-01 00:00:00

  • Preterm blood counts vary with sampling site.

    abstract::In preterm babies both haemoglobin and total neutrophil count values from capillary sites are significantly and variably higher than those from simultaneous arterial samples. Comparing simultaneous venous and arterial samples, the mean haemoglobin was slightly higher but the total neutrophil counts were similar. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.62.1.74

    authors: Thurlbeck SM,McIntosh N

    更新日期:1987-01-01 00:00:00

  • Chlamydia trachomatis as a cause of neonatal conjunctivitis.

    abstract::Chlamydia trachomatis was identified in 37 of 73 consecutive neonates with purulent conjunctivitis, including four delivered by caesarean section with intact membranes. Most (28/37) presented in the first week. Infection was significantly associated with referral from the community. Genital C. trachomatis infection wa...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.8.797

    authors: Barry WC,Teare EL,Uttley AH,Wilson SA,McManus TJ,Lim KS,Gamsu H,Price JF

    更新日期:1986-08-01 00:00:00

  • Hypertension associated with increased renin concentrations in nephroblastoma.

    abstract::An infant with severe hypertension who had a nephroblastoma which was secreting active renin is described. Nephroblastoma must be included in the differential diagnosis of hypertension associated with increased renin concentrations, even in the absence of an abdominal mass. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.66.4.525

    authors: Khan AB,Carachi R,Leckie BJ,Lindop GB

    更新日期:1991-04-01 00:00:00

  • Hidden sources of fluid and sodium intake in ill newborns.

    abstract::Fluids used for flushing arterial catheters, bronchial lavage, and drug administration are not normally considered when assessing daily fluid intake, yet infants weighing less than 1000 g at birth gained up to 12 ml/kg/day of extra fluid and 2.4 mmol/kg/day (mean) of extra sodium from these hidden sources. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.61.7.695

    authors: Noble-Jamieson CM,Kuzmin P,Airede KI

    更新日期:1986-07-01 00:00:00

  • Congenital central hypoventilation syndrome. A report of successful experience with bilateral diaphragmatic pacing.

    abstract::Bilateral diaphragmatic pacing was successfully performed in an 18-month-old child with congenital central hypoventilation syndrome (Ondine's curse) as an alternative to long-term mechanical ventilation. Subsequent complications were related more to cor pulmonale and tracheostomy care than to the pacing itself. ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.55.11.901

    authors: Coleman M,Boros SJ,Huseby TL,Brennom WS

    更新日期:1980-11-01 00:00:00

  • Presentation and outcome of severe anticholinesterase insecticide poisoning.

    abstract:AIMS:To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS:Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January ...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.86.5.352

    authors: Verhulst L,Waggie Z,Hatherill M,Reynolds L,Argent A

    更新日期:2002-05-01 00:00:00

  • Attention deficit hyperactivity disorder: legal and ethical aspects.

    abstract::Attention deficit-hyperactivity disorder (ADHD) remains a controversial disorder, despite it now being a well validated clinical diagnosis. Ethical and legal issues are important in determining how doctors should behave in offering a diagnosis or treatment that may generate strong and unpredictable reactions from chil...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章,评审

    doi:10.1136/adc.2004.064576

    authors: Foreman DM

    更新日期:2006-02-01 00:00:00

  • Prospective surveillance study of medium chain acyl-CoA dehydrogenase deficiency in the UK.

    abstract:BACKGROUND:Medium chain acyl-CoA dehydrogenase (MCAD) deficiency is a common disorder of fatty acid oxidation in north west Europe. It is very variable in its clinical consequences and is believed to be considerably underdiagnosed. OBJECTIVE:To investigate the diagnosis and outcome of MCAD deficiency in the UK. METHO...

    journal_title:Archives of disease in childhood

    pub_type: 杂志文章

    doi:10.1136/adc.79.2.116

    authors: Pollitt RJ,Leonard JV

    更新日期:1998-08-01 00:00:00