Liver cirrhosis in cystic fibrosis--therapeutic implications and long term follow up.

abstract：:A novel form of severe, X linked mental retardation associated with alpha thalassaemia (ATR-X syndrome) has recently been described. Two affected cousins are described, one of whom has an unusually mild haematological phenotype. HbH inclusions, which are the hallmark of this disease, were only detected in the peripher...

journal_title：Archives of disease in childhood

authors： Logie LJ,Gibbons RJ,Higgs DR,Brown JK,Porteous ME

更新日期：1994-05-01 00:00:00

abstract：:Gross neuropathy consequent upon selective malabsorption of vitamin B12 was diagnosed in a 6 year old Bangladeshi girl brought to Great Britain for further investigation of an unexplained illness of three years' duration. The initial peripheral blood count was normal. Treatment with vitamin B12 has led to substantial ...

journal_title：Archives of disease in childhood

authors： Conway SP,Gillies DR,Littlewood JM

更新日期：1984-06-01 00:00:00

abstract：:Obesity is becoming a common clinical headache for child health professionals, as the increase in professional and media concern has not been matched by effective clinical solutions. Added to this is considerable confusion about both the definitions of obesity and about which groups of children and adolescents actuall...

journal_title：Archives of disease in childhood

authors： Viner R,Nicholls D

更新日期：2005-04-01 00:00:00

abstract：:Vision screening of 13 and 15 year old children by school nurses in Oxfordshire has declined in recent years due to the pressure of other commitments. A study was carried out to evaluate the likely consequences of failing to provide vision screening for secondary schoolchildren, in order to make a decision about the f...

journal_title：Archives of disease in childhood

authors： Jewell G,Reeves B,Saffin K,Crofts B

更新日期：1994-01-01 00:00:00

abstract：AIMS:To study the prevalence of tuberculosis infection among children in household contact with adults having pulmonary tuberculosis, and identify the possible risk factors. METHODS:Children under the age of 5 years who were in household contact with 200 consecutive adults with pulmonary tuberculosis underwent tubercu...

journal_title：Archives of disease in childhood

authors： Singh M,Mynak ML,Kumar L,Mathew JL,Jindal SK

更新日期：2005-06-01 00:00:00

abstract：:The partial androgen insensitivity syndrome occurs in 46,XY subjects with phenotypes ranging from perineoscrotal hypospadias with cryptorchidism and micropenis (mild undervirilisation) to clitoromegaly and partial labial fusion (marked undervirilisation). Within an affected family, wide variation in the degree of geni...

journal_title：Archives of disease in childhood

authors： Batch JA,Davies HR,Evans BA,Hughes IA,Patterson MN

更新日期：1993-04-01 00:00:00

abstract：:Doppler ultrasound was used to measure blood flow velocity in the anterior cerebral artery of six premature infants with posthaemorrhagic hydrocephalus, before and after intermittent cerebrospinal fluid (CSF) drainage, on 23 occasions. There was a significant increase in mean blood flow velocity after the drainage pro...

journal_title：Archives of disease in childhood

authors： Kempley ST,Gamsu HR

更新日期：1993-07-01 00:00:00

abstract：AIMS:To study how respiratory symptoms reported by children, with or without spirometry, could help to discriminate those with asthma from those without. METHODS:Respiratory symptoms (frequent cough, frequent phlegm, and wheezing) reported by 1646 schoolchildren (aged 8-12 years) in a respiratory questionnaire and the...

journal_title：Archives of disease in childhood

authors： Yu IT,Wong TW,Li W

更新日期：2004-06-01 00:00:00

abstract：:In a family in which the father carried a balanced translocation between chromosomes 15 and 22 two of his children had Prader-Willi syndrome and an unbalanced chromosome complement, having lost the proximal bands from the long arm of chromosome 15. His four other surviving children were normal but carried a balanced t...

journal_title：Archives of disease in childhood

authors： Fernandez F,Berry C,Mutton D

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To assess the benefit of nebulised amiloride added to the standard inpatient treatment of a respiratory exacerbation in cystic fibrosis. DESIGN:Prospective, randomised, double blind, placebo controlled trial. SUBJECTS:27 cystic fibrosis patients (mean age 12.8 years). SETTING:Two hospitals in Leeds, UK. R...

journal_title：Archives of disease in childhood

authors： Bowler IM,Kelman B,Worthington D,Littlewood JM,Watson A,Conway SP,Smye SW,James SL,Sheldon TA

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Mentoring is important for personal and professional development of doctors. Peer mentoring is a core skill in the UK paediatric postgraduate curriculum. However, there is a paucity of peer mentoring programmes aimed at postgraduate doctors in training (postgraduate trainees), and there are no such schemes w...

journal_title：Archives of disease in childhood

authors： Eisen S,Sukhani S,Brightwell A,Stoneham S,Long A

更新日期：2014-02-01 00:00:00

abstract：:A combined test of anterior pituitary function was used on 21 normal children. It shows that a comprehensive evaluation can be made of growth hormone, thyroid stimulating hormone, adrenocorticotrophic hormone, and gonadotrophin reserve. Simultaneous assessment of those peripheral glands associated with the anterior pi...

journal_title：Archives of disease in childhood

authors： Savage DC,Swift PG,Johnston PG,Goldie DJ,Murphy D

更新日期：1978-04-01 00:00:00

abstract：OBJECTIVE:There is limited information on the psychosocial impact of growing up with Silver-Russell syndrome (SRS), characterised by slow growth in utero leading to short stature in adulthood. Such information could aid families in making difficult treatment decisions and guide management strategies for health professi...

journal_title：Archives of disease in childhood

authors： Ballard LM,Jenkinson E,Byrne CD,Child JC,Davies JH,Inskip H,Lokulo-Sodipe O,Mackay DJG,Wakeling EL,Temple IK,Fenwick A

更新日期：2019-01-01 00:00:00

abstract：:Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...

journal_title：Archives of disease in childhood

authors： Ngwane E,Bower B

更新日期：1980-03-01 00:00:00

abstract：:Coeliac disease occurred at the same age in MZ twins. The diagnosis was confirmed by histology of the small intestine, rapid response to a gluten-free diet, and relapse after reintroduction of gluten. ...

journal_title：Archives of disease in childhood

authors： Penna FJ,Mota JA,Roquete ML,de Carvalho AS,de Oliveira Lemos AT,Barbosa AJ,Leao E,Ferreira RA,de Paula Castro L

更新日期：1979-05-01 00:00:00

abstract：:Remarkable advances have been made over the past decade in defining the burden of newborn mortality and morbidity and stillbirths, and in identifying interventions to address the major risk factors and causes of deaths. However, progress in saving newborn lives and preventing stillbirths in countries lags behind that ...

journal_title：Archives of disease in childhood

authors： Darmstadt GL,Shiffman J,Lawn JE

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：:A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes insipidus. When she was 15 months old, the infusion of vasopressin did not produce an increase in urinary cyclic-A...

journal_title：Archives of disease in childhood

authors： Schreiner RL,Skafish PR,Anand SK,Northway JD

更新日期：1978-11-01 00:00:00

abstract：INTRODUCTION:Intravenous paracetamol (acetaminophen) has recently been registered for treatment of pain in neonates but the pharmacodynamics, including effects on body temperature, have not been reported. METHODS:A pooled analysis on body temperature recordings in neonates exposed to intravenous paracetamol was perfor...

journal_title：Archives of disease in childhood

authors： Hopchet L,Kulo A,Rayyan M,Verbesselt R,Vanhole C,de Hoon JN,Allegaert K

更新日期：2011-03-01 00:00:00

abstract：:This study evaluated the accuracy of the interpretation of the chest film in delineating localised abnormalities of ventilation and perfusion, as well as the overall severity of airways obstruction, exercise tolerance, and clinical condition in children with cystic fibrosis. Radiographic findings in various regions of...

journal_title：Archives of disease in childhood

authors： Coates AL,Boyce P,Shaw DG,Godfrey S,Mearns M

更新日期：1981-02-01 00:00:00

abstract：:A cohort of 164 children born within the defined boundaries of greater Manchester during the years 1981 to 1984 inclusive were identified as having bilateral sensorineural hearing loss, giving a prevalence of 1.2/1000 population of 1/817 births. Ninety three children developed an additional conductive hearing loss sec...

journal_title：Archives of disease in childhood

authors： Das VK

更新日期：1990-07-01 00:00:00

abstract：:Mortality from cystic fibrosis throughout childhood is more than twice as high in England and Wales than it is in the State of Victoria, Australia. Possible reasons for this difference are reviewed. ...

journal_title：Archives of disease in childhood

authors： Phelan P,Hey E

更新日期：1984-01-01 00:00:00

abstract：:Ninety-six Birmingham children with sickle cell disease were studied prospectively between 1969 and 1979. Thirty-five were homozygotes for HbS (SS), 12 had sickle thalassaemia (S thal), and 23 were double heterozygotes for HbS and C (SC). Twenty-six whose family studies were incomplete were classified as SS or S thal ...

journal_title：Archives of disease in childhood

authors： Mann JR

更新日期：1981-09-01 00:00:00

abstract：:A 9 month old boy presented with acute respiratory distress and was found to have a left pleural effusion. The chylous nature of the effusion, multiple bony lytic lesions, and splenic cysts lead to the diagnosis of congenital lymphangiomatosis with chylothorax. Surgical intervention including pleurectomy was required ...

journal_title：Archives of disease in childhood

authors： Dunkelman H,Sharief N,Berman L,Ninan T

更新日期：1989-07-01 00:00:00

abstract：:In acute paediatrics, overtreatment and overdiagnosis is encountered in threshold and developed countries. The reason for overtreatment may be similar in the two settings, namely the mere availability of invasive procedures, which may lead to their inappropriate use. Physiological healing processes should be integrate...

journal_title：Archives of disease in childhood

authors： Frey B

更新日期：2008-03-01 00:00:00

abstract：:Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient basis requires use of a sterile transport medium to facilitate bedside inoculation, maintain orga...

journal_title：Archives of disease in childhood

authors： Wright CA,Bamford C,Prince Y,Vermaak A,Hoek KG,Marais BJ,Warren RM

更新日期：2010-01-01 00:00:00

abstract：:A preterm infant with classic phenylketonuria required rather less than 90 mg/kg of phenylalanine and between 270 and 290 mg/kg tyrosine daily to achieve a rate of weight gain of around 20 g/kg per day. Using Lofenalac as the low phenylalanine food, the intake of tyrosine, an essential amino acid for patients with phe...

journal_title：Archives of disease in childhood

authors： Shortland D,Smith I,Francis DE,Ersser R,Wolff OH

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The epidemiology of congenital infections is ever changing, with a recent resurgence in syphilis infection rates seen in the UK. Identification of congenital infection is often delayed; early recognition and management of congenital infections is important. Testing modalities and investigations are often lim...

journal_title：Archives of disease in childhood

authors： Penner J,Hernstadt H,Burns JE,Randell P,Lyall H

更新日期：2021-02-01 00:00:00

abstract：:To assess the bacteriological quality of unpooled expressed breast milk, a pilot bottle sample of each donation was examined before the milk was given to the neonate. Provided the milk did not contain greater than 2500 organisms/ml or potential pathogens it was used unheated. Milk containing between 2500 and 5000 orga...

journal_title：Archives of disease in childhood

authors： Davidson DC,Poll RA,Roberts C

更新日期：1979-10-01 00:00:00

abstract：:Thirty preterm infants (gestational age 26 to 30 weeks) were investigated by cross sectional echocardiography using a 5 or 7.5 MHz transducer positioned in the suprasternal notch or the left subclavicular position to enable visualisation of the aortic arch, main pulmonary artery, left pulmonary artery, and ductus arte...

journal_title：Archives of disease in childhood

authors： Rigby ML,Pickering D,Wilkinson A

更新日期：1984-04-01 00:00:00