Alpha thalassaemia mental retardation (ATR-X): an atypical family.

abstract：BACKGROUND:Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity. AIM:To determine the incidence and risk factors for skeletal morbidity in ALL children. PATIENTS AND METHODS:The medical records of all (n=186, boys=110) children presenting to a single centre ...

journal_title：Archives of disease in childhood

authors： Elmantaser M,Stewart G,Young D,Duncan R,Gibson B,Ahmed SF

更新日期：2010-10-01 00:00:00

abstract：:Renal sodium handling was studied in 23 children at three different stages of the minimal change nephrotic syndrome--the oedema forming state, proteinuric steady state, and remission. Clearances of inulin and para-aminohippuric acid and urinary sodium excretion were determined basally, after intravenous infusion of is...

journal_title：Archives of disease in childhood

authors： Bohlin AB,Berg U

更新日期：1984-09-01 00:00:00

abstract：:In depth confidential inquiries on all post-perinatal infant deaths were carried out for two years in North and Southern Derbyshire District Health Authorities in order to explore why the postperinatal death rates and cot death rates have been consistently higher in Southern than in North Derbyshire. It was found that...

journal_title：Archives of disease in childhood

authors： Newlands M,Adamson E,Ghulam S,Saleh M,Emery JL

更新日期：1991-12-01 00:00:00

abstract：:An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...

journal_title：Archives of disease in childhood

authors： Manning DJ,Gray TA

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The epidemiology of congenital infections is ever changing, with a recent resurgence in syphilis infection rates seen in the UK. Identification of congenital infection is often delayed; early recognition and management of congenital infections is important. Testing modalities and investigations are often lim...

journal_title：Archives of disease in childhood

authors： Penner J,Hernstadt H,Burns JE,Randell P,Lyall H

更新日期：2021-02-01 00:00:00

abstract：AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age ...

journal_title：Archives of disease in childhood

authors： Hövels-Gürich HH,Konrad K,Wiesner M,Minkenberg R,Herpertz-Dahlmann B,Messmer BJ,Von Bernuth G

更新日期：2002-12-01 00:00:00

abstract：:The use of the Bene-Anthony Family Relations Test is described and illustrated by three examples of child abuse. This test should be considered in the investigation of definite or suspected cases of abuse and as part of the preparation of court evidence. ...

journal_title：Archives of disease in childhood

authors： Geddis DC,Turner IF,Eardley J

更新日期：1977-09-01 00:00:00

abstract：:The utility of point-of-care lung ultrasound in neonatology is rapidly expanding. This review summarises current evidence of a diagnostic, procedural and observational tool valuable in the management of newborns requiring intensive care. Approaching a patient, probe in-hand with focused clinical question is essential,...

journal_title：Archives of disease in childhood

authors： Woods PL

更新日期：2019-09-01 00:00:00

abstract：:The sodium intake of preschool children in their home environment was investigated and the major sources of sodium other than added table salt identified. Thirty five children from a Southampton general practice were studied. Twenty four hour urinary sodium excretion was measured as a reliable indicator of daily total...

journal_title：Archives of disease in childhood

authors： Allison ME,Walker V

更新日期：1986-02-01 00:00:00

abstract：METHODS:A total of 43 children with neurological signs and symptoms were enrolled in the study. All children were suspected of having meningitis, and lumbar punctures were performed. Human herpesvirus 6 (HHV-6) and HHV-7 DNA was detected in cerebrospinal fluid (CSF) and peripheral blood mononuclear cells (PBMC) by nest...

journal_title：Archives of disease in childhood

authors： Yoshikawa T,Ihira M,Suzuki K,Suga S,Matsubara T,Furukawa S,Asano Y

更新日期：2000-08-01 00:00:00

abstract：INTRODUCTION:Despite immunisation, antibiotics and intensive care management, infection with Streptococcus pneumoniae remains a major cause of morbidity and mortality in children. The WHO currently recommends vaccinating infants with either a 3+0 schedule (6 weeks, 3-4 and 4-6 months of age) or 2+1 schedule (2 doses be...

journal_title：Archives of disease in childhood

authors： Zimmermann P,Perrett KP,Berbers G,Curtis N

更新日期：2019-07-01 00:00:00

abstract：:A significant proportion of children with anorectal malformations have long term problems with faecal continence. The psychological consequences of this chronic disability was assessed in 160 children and adolescents. The prevalence of clinically significant emotional problems among the sample overall, as assessed by ...

journal_title：Archives of disease in childhood

authors： Ludman L,Spitz L,Kiely EM

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. The National Institute for Health and Care Excellence (NICE) has issued...

journal_title：Archives of disease in childhood

authors： Marlow R,Mytton J,Maconochie IK,Taylor H,Lyttle MD

更新日期：2015-12-01 00:00:00

abstract：:The changes in transcutaneous oxygen tension (TcPO2) during 123 observations of 10 care procedures were compared with the intrinsic variability of the TcPO2 at the time of the procedures. Standard deviations of the TcPO2 were measured by planimetry from continuous recording in undisturbed infants during a 10-minute co...

journal_title：Archives of disease in childhood

authors： Danford DA,Miske S,Headley J,Nelson RM

更新日期：1983-01-01 00:00:00

abstract：:During the 6-year period from 1 October 1971 to 30 September 1977, 13 (about 1%) of 1225 admissions to hospital with asthma developed severe ventilatory failure (peak arterial PCO 2 greater than 8 kPa). Mean age was 4.1 years (2.3--7.9), and on average each patient had been admitted to hospital on 5 occasions during t...

journal_title：Archives of disease in childhood

authors： Simpson H,Mitchell I,Inglis JM,Grubb DJ

更新日期：1978-09-01 00:00:00

abstract：:Blood lead concentrations and body iron status were investigated in 279 children. Blood lead concentrations showed no increase during iron depletion phase (stage I) but markedly increased from the phase of iron deficient erythropoiesis (stage II). Increased blood lead concentrations in anaemic subjects significantly d...

journal_title：Archives of disease in childhood

authors： Choi JW,Kim SK

更新日期：2003-09-01 00:00:00

abstract：:The British (Tanner and Whitehouse) and American (National Center for Health Statistics, NCHS) growth standards are widely used internationally, although the data are now over 30 years old. Routine weight data was retrieved from the child health records of a complete annual cohort of 3418 children aged 18-30 months to...

journal_title：Archives of disease in childhood

authors： Wright CM,Waterston A,Aynsley-Green A

更新日期：1993-10-01 00:00:00

abstract：:The metabolism and excretion of paracetamol was studied in an infant of 29 weeks' gestation who was exposed to the drug when his mother ingested 32.5 g 16 hours before delivery. We have confirmed that sulphation is the major pathway and that the mixed function oxidase system is sufficiently active at this gestational ...

journal_title：Archives of disease in childhood

authors： Lederman S,Fysh WJ,Tredger M,Gamsu HR

更新日期：1983-08-01 00:00:00

abstract：AIMS:To pilot a novel approach to providing pharmaceutical care to paediatric inpatients using structured referral and assessment tools. Using standardised referral criteria to ensure patients are assessed by appropriately skilled pharmacists. METHOD:Three wards of varying acuity and specialism were selected in a tert...

journal_title：Archives of disease in childhood

authors： Mott A,Kafka S,Sutherland A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Timing of referral to subspecialists may be a major determinant for access to adequate treatment. Kidney transplantation is the preferred modality of renal replacement therapy (RRT) in children. In adults, delayed referral from general physicians to nephrologists reduced access to kidney transplantation. Thi...

journal_title：Archives of disease in childhood

authors： Boehm M,Winkelmayer WC,Arbeiter K,Mueller T,Aufricht C

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Use next-generation sequencing (NGS) technology to improve our diagnostic yield in patients with suspected genetic disorders in the Asian setting. DESIGN:A diagnostic study conducted between 2014 and 2019 (and ongoing) under the Singapore Undiagnosed Disease Program. Date of last analysis was 1 July 2019. S...

journal_title：Archives of disease in childhood

authors： Bhatia NS,Lim JY,Bonnard C,Kuan JL,Brett M,Wei H,Cham B,Chin H,Bosso-Lefevre C,Dharuman P,Escande-Beillard N,Devasia AG,Goh CYJ,Kam S,Liew WK,Liew WK,Lin G,Jain K,Ng AY,Subramanian D,Xie M,Tan YM,Tawari NR,T

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The development, delivery and evaluation of a training programme for medical and nursing professionals on best practice for informing families of their child's disability. DESIGN:A 2 h training course on 'Best practice guidelines for informing families of their child's disability' was designed based on the f...

journal_title：Archives of disease in childhood

authors： Harnett A,Bettendorf E,Tierney E,Guerin S,O'Rourke M,Hourihane JO

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To study the relation between traumatic birth and the development of permanent facial palsy in the newborn. DESIGN:Retrospective case control study of children with 'congenital' facial palsy. SETTING:Two tertiary referral centres for patients with facial palsy. SUBJECTS:61 children with established facial ...

journal_title：Archives of disease in childhood

authors： Laing JH,Harrison DH,Jones BM,Laing GJ

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Chronic fatigue syndrome (CFS) in children is a controversial diagnosis with unclear aetiology, ill defined but likely increasing incidence, and debatable clinical management options. However these children experience real and considerable suffering. Appropriate research in this clinical population is sparse...

journal_title：Archives of disease in childhood

authors： Patel MX,Smith DG,Chalder T,Wessely S

更新日期：2003-10-01 00:00:00

abstract：:Over a two year period 100 infants with histories of wheeze were challenged with nebulised water. They were sedated and lung function measured by total body plethysmography. Thirteen of the 53 infants who developed bronchoconstriction after challenge with nebulised water were given nebulised sodium cromoglycate and re...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Milner AD,Swarbrick A

更新日期：1990-04-01 00:00:00

abstract：AIMS:To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic pyloric stenosis (IHPS) with special reference to regression of pyloric hypertrophy. METHODS:Atropine was given intravenously at a dose of 0.01 mg/kg six times a day before feeding in 19 patients with IHPS diagnos...

journal_title：Archives of disease in childhood

authors： Kawahara H,Imura K,Nishikawa M,Yagi M,Kubota A

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:It is often assumed that prolonged time to diagnosis (TTD) for cancer negatively influences overall survival and survivorship through advanced stage disease at diagnosis. This systematic review assesses existing early diagnosis research in childhood and young adult cancer and aims to identify whether a consensu...

journal_title：Archives of disease in childhood

authors： Lethaby CD,Picton S,Kinsey SE,Phillips R,van Laar M,Feltbower RG

更新日期：2013-05-01 00:00:00

abstract：:Thirty preterm infants (gestational age 26 to 30 weeks) were investigated by cross sectional echocardiography using a 5 or 7.5 MHz transducer positioned in the suprasternal notch or the left subclavicular position to enable visualisation of the aortic arch, main pulmonary artery, left pulmonary artery, and ductus arte...

journal_title：Archives of disease in childhood

authors： Rigby ML,Pickering D,Wilkinson A

更新日期：1984-04-01 00:00:00

abstract：AIMS:To evaluate a systematic approach to the development and implementation of evidence based asthma management guidelines. METHODS:Comparative study of children (2-18 years) with acute asthma; a control cohort (cohort 1) was recruited before implementation of the guidelines and two cohorts were recruited after imple...

journal_title：Archives of disease in childhood

authors： Massie J,Efron D,Cerritelli B,South M,Powell C,Haby MM,Gilbert E,Vidmar S,Carlin J,Robertson CF,ICAAM Study Group.

更新日期：2004-07-01 00:00:00

abstract：:Over a 25 year period, 31 asthmatic children received artificial ventilation for acute asthma at Alder Hey Children's Hospital on 48 occasions. Altogether 47 episodes occurred from 1971-89, with no decline in the number of episodes per year (mean 2.5) over this period. Eight children died during intermittent positive ...

journal_title：Archives of disease in childhood

authors： Seddon PC,Heaf DP

更新日期：1990-12-01 00:00:00