Abstract:
BACKGROUND:The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. The National Institute for Health and Care Excellence (NICE) has issued three iterations of evidence-based national guidance for head injury since 2003. OBJECTIVES:To assess if any changes in the rates of admission, death or causes of head injury could be temporally associated with the introduction of sequential national guidelines by longitudinal analysis of the epidemiology of paediatric head injury admissions in England from 2000 to 2011. METHODS:Retrospective analysis of English Hospital Episode Statistics data of children under the age of 16 years old admitted to hospital with the discharge diagnosis of head injury. RESULTS:The number of hospital admissions with paediatric head injury in England rose by 10% from 34 150 in 2000 to 37 430 in 2011, with the proportion admitted for less than 1 day rising from 38% to 57%. The main cause of head injury was falls (42-47%). Deaths due to head injury decreased by 52% from 76 in 2000 to 40 in 2011. Road traffic accidents were the main cause of death in the year 2000 (67%) but fell to 40% by 2011. In 2000, children who were admitted or died from head injuries were more than twice as likely to come from the most deprived homes compared with least deprived homes. By 2011, the disparity for risk of admission had narrowed, but no change was seen for risk of death. CONCLUSIONS:Temporal relationships exist between implementation of NICE head injury guidance and increased admissions, shorter hospital stay and reduced mortality. The underlying cause of this association is likely to be multifactorial.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Marlow R,Mytton J,Maconochie IK,Taylor H,Lyttle MDdoi
10.1136/archdischild-2015-308615subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1136-40issue
12eissn
0003-9888issn
1468-2044pii
archdischild-2015-308615journal_volume
100pub_type
杂志文章abstract::The clinical, radiological, and biochemical features of 2 male children with mannosidosis are described. Superficially they appeared to suffer from Hurler's syndrome, but the facies, eye signs, radiological and cytological features were atypical. Excess urinary oligosaccharides were found by thin-layer chromatography....
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.12.937
更新日期:1977-12-01 00:00:00
abstract::Endogenous formation of thromboxane A2 and prostacyclin were evaluated in seven neonatates with persistent pulmonary hypertension by serial gas chromatographic mass spectrometric determination of their urinary metabolites dinor-thromboxane B2 and dinor-6-keto-prostaglandin F1 alpha, respectively. The patients were stu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.64.7_spec_no.949
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:The atherogenic risk factor profile in obese subjects is characterised by hypertension, reduced high density lipoprotein (HDL) cholesterol, increased low density lipoprotein (LDL) cholesterol and triglycerides, and insulin resistance. AIMS:To examine the amount of weight reduction required to improve the at...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2003.028803
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:There are few data on the optimal micronutrient composition of paediatric enteral feeds. The recent European Directive on Foods for Special Medical Purposes (1999/21/EC) did not distinguish between the composition of adult and paediatric feeds. AIMS:To evaluate, in an open, observational study, the long ter...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.86.6.411
更新日期:2002-06-01 00:00:00
abstract::Fifty-one children with a bacteriologically proven urinary tract infection had both an intravenous urogram (IVU) and a micturating cystogram. The IVU was normal in 35. Only 6 of these children showed reflux in the cystogram, affecting 7 of the 70 ureters at risk. Since reflux on its own does not cause renal damage, wh...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.11.893
更新日期:1976-11-01 00:00:00
abstract:OBJECTIVE:Moderately preterm children (gestational age 32-36+6 weeks) are at risk of cognitive and behaviour problems at school age. The aim of this study was to investigate if these problems are already present at the age of 2 years. STUDY DESIGN:Developmental outcome was assessed at 24-months (corrected age) with th...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2014-307016
更新日期:2015-06-01 00:00:00
abstract::Over 15 years, 42 children aged 2-14 years were diagnosed as having acquired aplastic anaemia. Adequate clinical details were available for 38 children who were categorised as very severe (n = 13), severe (n = 16), or nonsevere (n = 9) by the modified Camitta criteria. Treatment varied over the study period. Seven chi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.7.858
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:Inconsistencies have been reported in health-related quality of life (HRQOL) in postoperative congenital heart disease (CHD). Despite the need for lifelong care due for residual symptoms, only a few studies have explored cardiac-related HRQOL but none in lower middle-income countries (LMIC). This study theref...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2018-315594
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:We assessed whether maternal mental health problems increased rates for child injury during the preschool years and mid-childhood, and the extent to which associations could be accounted for by a range of potential explanatory factors. DESIGN:We analysed the UK Millennium Cohort Study, a nationally represent...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2017-313809
更新日期:2019-03-01 00:00:00
abstract::36 parents of infants who had died suddenly did not differ in frequency of atopic symptoms, immediate skin tests, IgE, IgE antibody, immunoglobulin G, A, and M, or yeast opsonisation, from 36 matched controls, although atopy was common (about half had atopy in both groups. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.11.876
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:Faecal impaction is frequently observed in children with chronic constipation. The term megarectum is often used to describe this finding. AIM:To evaluate rectal functioning and rectal measures in constipated children with a filled rectum, in order to define the terms faecal impaction, enlarged rectum, and ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.83.1.52
更新日期:2000-07-01 00:00:00
abstract::Chlamydia trachomatis was identified in 37 of 73 consecutive neonates with purulent conjunctivitis, including four delivered by caesarean section with intact membranes. Most (28/37) presented in the first week. Infection was significantly associated with referral from the community. Genital C. trachomatis infection wa...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.8.797
更新日期:1986-08-01 00:00:00
abstract::Advances in paediatric care mean that more children with complex medical problems (heart disease, neurodevelopmental problems and so on) are surviving their early years. This has important implications for the design and delivery of healthcare given their extensive multidisciplinary requirements and susceptibility to ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2019-317373
更新日期:2020-05-13 00:00:00
abstract::Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments i...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.82.3.238
更新日期:2000-03-01 00:00:00
abstract::Seventy six children, 18 boys and 58 girls, aged 0-15.9 (median 1.0) years, with acute pyelonephritis were prospectively studied with a technetium-99m dimercaptosuccinic acid (DMSA) scan during infection and two months later. Fifty nine of these children were also studied two years after the infection. Seventeen child...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.70.2.111
更新日期:1994-02-01 00:00:00
abstract::Nocturnal growth hormone secretion over a 12 hour period was assessed at 20 minute intervals in 25 prepubertal subjects with Turner's syndrome and 11 normal prepubertal girls of short stature to try and elucidate the relationship between body weight and endogenous secretion of growth hormone in Turner's syndrome. Ther...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.10.1184
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:(1) To determine the prevalence of cough, wheeze, and breathlessness, both as single symptoms and in combination, in primary schoolchildren and their relation to doctor diagnosed asthma. (2) To identify in areas with different levels of dust pollution whether questionnaire reported 'cough alone' (without whe...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.6.489
更新日期:1996-12-01 00:00:00
abstract::Two cross sectional surveys, 24 years apart, using the same respiratory questionnaire, were carried out to examine changes in prevalence rates of cough, phlegm, and wheeze and to relate changes in wheeze to objective peak expiratory flow rates (PEFRs). The surveys were done in towns in southern and northern England an...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.6.729
更新日期:1993-06-01 00:00:00
abstract::Clinical observations and findings on imaging are reported in six newborns with symmetrical thalamic lesions (STL). In three cases the diagnosis was confirmed by postmortem examination. Characteristic observations in this series and 17 previously reported cases include no evidence of perinatal asphyxia, high incidence...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.67.1_spec_no.15
更新日期:1992-01-01 00:00:00
abstract::Serum antitoxoplasma titres were determined simultaneously by the direct agglutination and the indirect immunofluorescent tests in 52 children aged 2 to 16 years having chronic lymph node enlargement, mainly cervical. Direct agglutination titres were raised (64 to 4096) in 22 children (42%), but rarely in the control ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.5.403
更新日期:1977-05-01 00:00:00
abstract:AIMS:To prospectively evaluate sinopulmonary disease in 24 patients with primary humoral immunodeficiency (11 with agammaglobulinaemia, nine with isolated IgA deficiency, and two with common variable immunodeficiency) and chronic productive cough, ascertain the usefulness of chest high resolution computed tomography (H...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.12.1101
更新日期:2003-12-01 00:00:00
abstract::Three neonates with rectal perforations probably caused by the use of the rectal thermometer, are reported. The dangers of this condition and the difficulty of diagnosis even at laporatomy are emphasised. It is suggested that since the axillary temperature in the neonate is an adequate reflection of the core temperatu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.10.824
更新日期:1978-10-01 00:00:00
abstract::Children with end stage renal failure and anaemia have an increased cardiac index and often gross ventricular hypertrophy. Correction of anaemia with recombinant human erythropoietin (r-HuEpo) for less than six months results in a reduction in the cardiac index without a significant reduction in left ventricular hyper...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.71.2.119
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVE:Investigate whether hyoscine patch or glycopyrronium liquid is more effective and acceptable to treat drooling in children with neurodisability. DESIGN:Multicentre, single-blind, randomised controlled trial. SETTING:Recruitment through neurodisability teams; treatment by parents. PARTICIPANTS:Ninety childr...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/archdischild-2017-313763
更新日期:2018-04-01 00:00:00
abstract:AIMS:To describe the epidemiology of children with traumatic brain injury (TBI) admitted to paediatric intensive care units (PICUs) in the UK. METHODS:Prospective collection of clinical and demographic information from paediatric and adult intensive care units in the UK and Eire between February 2001 and August 2003. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2005.072405
更新日期:2005-11-01 00:00:00
abstract::Interstitial nephritis was diagnosed at renal biopsy in 10 previously healthy children. All had identical clinical symptoms: anaemia, raised sedimentation rate, low glomerular filtration rate, protein and leucocytes in the urine, but no bacteria; nine also had glycosuria. Six of the children had a history of recent in...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.8.752
更新日期:1985-08-01 00:00:00
abstract::Lymphocytes bearing the T cell receptor gamma delta (TCR-gamma delta) were searched for in human early milk lymphocyte suspensions by two colour cytofluorimetric analysis. It was found that the proportion of TCR-gamma delta+ cells was twofold greater in colostrum than in either autologous or heterologous blood samples...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.11.1274-a
更新日期:1990-11-01 00:00:00
abstract::The serum concentrations of the phagocytosis-stimulating peptide, tuftsin, were determined by radioimmunoassay in 21 patients with sickle cell disease and in 12 healthy controls. The mean serum tuftsin concentration was significantly lower in patient with haemoglobin SS disease (154.3 +/- 35.1 ng/ml; 308.6 +/- 70.2 nm...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.7.566
更新日期:1980-07-01 00:00:00
abstract::West, R. J., Lloyd, J. K., and Turner, W. M. L. (1975). Archives of Disease in Childhood, 50, 703. Familial insulin-resistant diabetes, multiple somatic anomalies, and pineal hyperplasia. A syndrome comprising unusual facies, dry skin, acanthosis nigricans, thickened nails, hirsutism, dental precocity and dysplasia, a...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.50.9.703
更新日期:1975-09-01 00:00:00
abstract::Increased emphasis on strict glycaemic control of insulin dependent diabetes mellitus (IDDM) in young patients may be expected to cause increases in rates of significant hypoglycaemia. To evaluate whether this is the case for a large population based sample of IDDM children and adolescents rates of severe (coma, convu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.78.2.111
更新日期:1998-02-01 00:00:00