Sickle cell haemoglobinopathies in England.

abstract：:UK guidelines for HIV post-exposure prophylaxis (PEP) in adults have recently been updated. Indications for PEP have been modified and there has been a change in the recommended antiretroviral therapy for adults to a combination of raltegravir with tenofovir and emtricitabine (Truvada). Raltegravir and tenofovir are n...

journal_title：Archives of disease in childhood

authors： Bamford A,Tudor-Williams G,Foster C

更新日期：2017-01-01 00:00:00

abstract：:Six neonates with aneurysms of the vein of Galen are described: five were associated with an intracerebral arteriovenous fistula and presented with heart failure in the neonatal period; one had hydrocephalus at birth. Two infants died from intractable cardiac failure within 48 hours of age and two from progressive hyd...

journal_title：Archives of disease in childhood

authors： O'Donnabhain D,Duff DF

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:To study the epidemiology of pyridoxine dependent seizures and other forms of pyridoxine responsive seizures. DESIGN:Monthly notifications to the British Paediatric Surveillance Unit over two years. Questionnaire follow up. SETTING:UK and the Republic of Ireland. PATIENTS:Children aged 15 years or younger ...

journal_title：Archives of disease in childhood

authors： Baxter P

更新日期：1999-11-01 00:00:00

abstract：:Four Asian babies were investigated because they failed to thrive. In all four cases the failure to thrive was a result of the mother's social isolation and inability to communicate, and to the father's refusal to accept that there was a problem in the family. ...

journal_title：Archives of disease in childhood

authors： Fenton TR,Bhat R,Davies A,West R

更新日期：1989-03-01 00:00:00

abstract：:Six healthy children, born in the UK, travelled to their parental homeland and developed a severe form of traveller's diarrhoea. This was characterised by rapid loss of weight and chronic diarrhoea. On return to this country, investigation in 5 of them showed an abnormal, small intestinal mucosa. There was a high inci...

journal_title：Archives of disease in childhood

authors： Hutchins P,Hindocha P,Phillips A,Walker-Smith J

更新日期：1982-03-01 00:00:00

abstract：:All 212 neonates undergoing cardiac surgery at this hospital during the 5-year period from 1976 to 1980 inclusive were reviewed. Forty required open heart surgery with 23 (57%) deaths. One hundred and seventy-four neonates underwent non-bypass procedures and could be divided into three groups: group 1 (82 patients) ha...

journal_title：Archives of disease in childhood

authors： Bove EL,Bull C,Stark J,de Leval M,Macartney FJ,Taylor JF

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Our current understanding regarding the aetiology of infantile acute liver failure largely derives from studies conducted by regional liver units. This may introduce selection bias and therefore not provide a true reflection of the wider population. METHODS:Every coagulation screen with a prothrombin time ≥...

journal_title：Archives of disease in childhood

authors： Wands D,Tayler R,Kelly D,Pinto F,Simpson JH,Hansen R

更新日期：2020-08-01 00:00:00

abstract：:A preterm infant with classic phenylketonuria required rather less than 90 mg/kg of phenylalanine and between 270 and 290 mg/kg tyrosine daily to achieve a rate of weight gain of around 20 g/kg per day. Using Lofenalac as the low phenylalanine food, the intake of tyrosine, an essential amino acid for patients with phe...

journal_title：Archives of disease in childhood

authors： Shortland D,Smith I,Francis DE,Ersser R,Wolff OH

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To explore the effect of research ethics, governance and consent requirements and recent reforms on UK-wide follow-up of children with congenital heart defects (CHD). DESIGN:Prospective cohort study. SETTING:UK National Health Service. PATIENTS:3897 children with CHD requiring intervention, or resulting in...

journal_title：Archives of disease in childhood

authors： Knowles RL,Bull C,Wren C,Dezateux C

更新日期：2011-01-01 00:00:00

abstract：AIMS:To pilot a novel approach to providing pharmaceutical care to paediatric inpatients using structured referral and assessment tools. Using standardised referral criteria to ensure patients are assessed by appropriately skilled pharmacists. METHOD:Three wards of varying acuity and specialism were selected in a tert...

journal_title：Archives of disease in childhood

authors： Mott A,Kafka S,Sutherland A

更新日期：2016-09-01 00:00:00

abstract：:Kwashiorkor and marasmus, collectively termed severe acute malnutrition (SAM), account for at least 10% of all deaths among children under 5 years of age worldwide, virtually all of them in low-income and middle-income countries. A number of risk factors, including seasonal food insecurity, environmental enteropathy, ...

journal_title：Archives of disease in childhood

authors： Trehan I,Manary MJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Vanessa is a 34-year-old lawyer married to a police officer. Her first baby was born after a perfect pregnancy and labour until fetal distress necessitated an easy Ventouse extraction late in the second stage. Baby F had normal Apgar scores and weighed 2920 g. This paper records a conversation between Vaness...

journal_title：Archives of disease in childhood

authors： Harris V,Hall D

更新日期：2007-01-01 00:00:00

abstract：:A boy with the dysmorphic features of Noonan's syndrome and pulmonary valve stenosis who had evidence of hypoparathyroidism and abnormal T lymphocyte numbers in the neonatal period is reported. He had a normal karyotype but molecular analysis revealed a submicroscopic deletion within chromosome 22q11, the region delet...

journal_title：Archives of disease in childhood

authors： Wilson DI,Britton SB,McKeown C,Kelly D,Cross IE,Strobel S,Scambler PJ

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:Assays based on interferon gamma (IFNgamma) are an exciting new development for screening for latent tuberculosis infection (LTBI) in adults, but there are limited data on their effectiveness in children. Nevertheless new National Institute for Health and Clinical Excellence (NICE) guidelines recommend their ...

journal_title：Archives of disease in childhood

authors： Taylor RE,Cant AJ,Clark JE

更新日期：2008-03-01 00:00:00

abstract：:An 11 year old girl developed progressive upper gastrointestinal ulceration and recurrent episodes of intravenous catheter associated polymicrobial septicaemia. Evaluation failed to establish a cause. After exclusion of the parents and careful surveillance of the patient she improved, supporting the diagnosis of suspe...

journal_title：Archives of disease in childhood

authors： Rubin LG,Angelides A,Davidson M,Lanzkowsky P

更新日期：1986-09-01 00:00:00

abstract：:A picture archiving and communication system (PACS) is a computerised means of replacing the roles of conventional radiological film. This review describes the Hammersmith PACS, and discusses the advantages and disadvantages of PACS systems. ...

journal_title：Archives of disease in childhood

authors： Strickland NH

更新日期：2000-07-01 00:00:00

abstract：:Forty six of 142 infants weighing less than 1500 g at birth, who had chest radiographs in the first 5 days of life, developed pulmonary interstitial emphysema (PIE) and in 19 this occurred in the first 24 hours. PIE was seen more frequently in infants weighing less than 1000 g at birth (24 of 57) than in those weighin...

journal_title：Archives of disease in childhood

authors： Hart SM,McNair M,Gamsu HR,Price JF

更新日期：1983-08-01 00:00:00

abstract：:The National Health Service, in its report An organisation with memory, has called for a fundamental rethinking of the way the healthcare system learns from error. The NHS further details its goal to reduce serious medication errors by 40% in a second report entitled Building a safer NHS: improving medication safety. ...

journal_title：Archives of disease in childhood

authors： Walsh KE,Kaushal R,Chessare JB

更新日期：2005-07-01 00:00:00

abstract：:In a multicentre study on perinatal HIV-I infection including 1493 children born from 1471 pregnancies to 1415 infected mothers, 22 twin pairs and 56 sibships (115 children) were recorded. The frequency of twin pregnancies was 1.5 (22/1471) and 3.9% (56/1415) seropositive women had more than one at risk pregnancy. In ...

journal_title：Archives of disease in childhood

authors： de Martino M,Tovo PA,Galli L,Caselli D,Gabiano C,Mazzoni PL,Giacomelli A,Duse M,Fundarò C

更新日期：1991-10-01 00:00:00

abstract：:A study was performed to compare adverse events and antibody response in term and preterm children vaccinated with diphtheria, tetanus, and pertussis vaccine at 2, 3, and 4 months of age. A total of 124 children were recruited and grouped according to gestational age: 37 weeks or more (n = 52), 34 to 36 weeks (n = 40)...

journal_title：Archives of disease in childhood

authors： Ramsay ME,Miller E,Ashworth LA,Coleman TJ,Rush M,Waight PA

更新日期：1995-03-01 00:00:00

abstract：:This study describes the pattern of oxygen consumption (VO2), rectal temperature (Tr), and acral skin temperature (Tac) in sleeping and resting (awake) burned children nursed in a thermoneutral environment. Measurements of respiratory gas exchange (VO2 and carbon dioxide production (VCO2)) were made using an open circ...

journal_title：Archives of disease in childhood

authors： Childs C,Little RA

更新日期：1994-07-01 00:00:00

abstract：:Over a 25 year period, 31 asthmatic children received artificial ventilation for acute asthma at Alder Hey Children's Hospital on 48 occasions. Altogether 47 episodes occurred from 1971-89, with no decline in the number of episodes per year (mean 2.5) over this period. Eight children died during intermittent positive ...

journal_title：Archives of disease in childhood

authors： Seddon PC,Heaf DP

更新日期：1990-12-01 00:00:00

abstract：:Forty three infants were assigned randomly to a ready-to-feed infant formula or a standard formula that required reconstitution from powder. Despite similar nutrient composition of the two formulas those fed the powdered formula had significantly increased body weight and skinfold thickness gains, and became significa...

journal_title：Archives of disease in childhood

authors： Lucas A,Lockton S,Davies PS

更新日期：1992-07-01 00:00:00

abstract：:Monthly increments of length, weight gain, and head circumference were recorded from birth to 4 years of age in 52 children with cystic fibrosis. At birth the children showed stunting. Standard deviation (SD) scores at birth for height, weight, and head circumference were -1.24, -0.72, and -1.82 respectively. Over the...

journal_title：Archives of disease in childhood

authors： Ghosal S,Taylor CJ,Pickering M,McGaw J,Beckles-Willson N,Wales JK

更新日期：1995-02-01 00:00:00

abstract：:The variability of cerebral blood flow velocity was measured in 20 very low birthweight infants. The area under the curve of the Doppler frequency spectrum was used and was obtained from the anterior cerebral artery in the infants before and after infusions of plasma or dopamine. Both interventions significantly reduc...

journal_title：Archives of disease in childhood

authors： Rennie JM

更新日期：1989-07-01 00:00:00

abstract：:Mortality from cystic fibrosis throughout childhood is more than twice as high in England and Wales than it is in the State of Victoria, Australia. Possible reasons for this difference are reviewed. ...

journal_title：Archives of disease in childhood

authors： Phelan P,Hey E

更新日期：1984-01-01 00:00:00

abstract：:Two hundred children with glass injuries were investigated; 48 were injured in falls through architectural glass and 87 by broken bottles. Nine children had serious lacerations--7 of which were sustained at home. Radiographs were important in diagnosing retained fragments but prophylactic antibiotics were unnecessary....

journal_title：Archives of disease in childhood

authors： Bell D

更新日期：1984-07-01 00:00:00

abstract：:Two cross sectional surveys, 24 years apart, using the same respiratory questionnaire, were carried out to examine changes in prevalence rates of cough, phlegm, and wheeze and to relate changes in wheeze to objective peak expiratory flow rates (PEFRs). The surveys were done in towns in southern and northern England an...

journal_title：Archives of disease in childhood

authors： Whincup PH,Cook DG,Strachan DP,Papacosta O

更新日期：1993-06-01 00:00:00

abstract：:The benefits of achieving a long term event free survival of 60-70% by using increasingly intense treatment regimens must be weighed against the increased risk of treatment toxicity. From 1985 to 1990, 1612 children with childhood acute lymphoblastic leukaemia (ALL) in the UK were treated on MRC UKALL X with intensive...

journal_title：Archives of disease in childhood

authors： Wheeler K,Chessells JM,Bailey CC,Richards SM

更新日期：1996-02-01 00:00:00

abstract：AIM:To measure drug adherence in children with mild asthma receiving long term prophylactic treatment. METHODS:Double blind randomised placebo controlled trial. Patients received inhaled budesonide 100 microg or 200 microg daily, or placebo for 27 months. All participants were asked to inhale medication or placebo fro...

journal_title：Archives of disease in childhood

authors： Jónasson G,Carlsen KH,Mowinckel P

更新日期：2000-10-01 00:00:00