Effect of cyproterone acetate on adrenocortical function in children with precocious puberty.

Abstract:

:Seven children with precocious puberty were treated with cyproterone acetate and their adrenal function studied. In each child the drug caused significant adrenal hypofunction which was secondary to adrenocorticotrophic hormone suppression. None of these children had clinical evidence of adrenal hypofunction and it is assumed that the drug has glucocorticoid-like properties. Children receiving cyproterone acetate should carry information to warn doctors of this effect since they may require steroid cover during illness.

journal_name

Arch Dis Child

authors

Savage DC,Swift PG

doi

10.1136/adc.56.3.218

subject

Has Abstract

pub_date

1981-03-01 00:00:00

pages

218-22

issue

3

eissn

0003-9888

issn

1468-2044

journal_volume

56

pub_type

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