Hypocalcaemia in severe meningococcal infections.

Abstract:

AIM:To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS:In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical diagnosis of meningococcal disease to intensive care had measurements of total and ionised calcium on admission. Parathormone and calcitonin were measured in a proportion of the children. RESULTS:Total and ionised calcium concentrations were low in 70% of the children. There was a weak relation of calcium concentration to the volume of blood derived colloid which had been given, but a good relation to disease severity, where sicker children had lower calcium concentrations. Although the parathormone concentration was higher in children with lower calcium concentrations, some children had low ionised calcium concentrations, without an increase of parathormone concentration. Serum calcitonin concentration was not related to calcium concentrations. CONCLUSION:Hypocalcaemia is common in meningococcal disease.

journal_name

Arch Dis Child

authors

Baines PB,Thomson AP,Fraser WD,Hart CA

doi

10.1136/adc.83.6.510

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

510-3

issue

6

eissn

0003-9888

issn

1468-2044

journal_volume

83

pub_type

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