Abstract:
OBJECTIVES:To determine the effectiveness of auditory integration training (AIT) or other methods of sound therapy in people with autism spectrum disorders (ASD). STUDY DESIGN:A systematic review was carried out of randomised controlled trials (RCTs) of adults or children with ASD. Meta-analysis was attempted. RESULTS:Six RCTs of AIT, including one crossover trial, were identified, with a total of 171 participants aged 3-39 years. 17 different outcome measures were used, with only two outcome measures used by three or more studies. Meta-analysis was not possible owing to very high heterogeneity or presentation of data in unusable forms. Three studies did not show any benefit of AIT over control conditions. Three studies reported improvements at 3 months in the AIT group for total mean scores of the Aberrant Behaviour Checklist (ABC), which is of questionable validity. Of these, one study also reported improvements at 3 months in the AIT group for ABC subgroup scores. No significant adverse effects of AIT were reported. CONCLUSION:At present there is not sufficient evidence to support its use.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Sinha Y,Silove N,Wheeler D,Williams Kdoi
10.1136/adc.2006.094649subject
Has Abstractpub_date
2006-12-01 00:00:00pages
1018-22issue
12eissn
0003-9888issn
1468-2044pii
adc.2006.094649journal_volume
91pub_type
杂志文章,meta分析,评审abstract::The clinical course of 6 children with primary intestinal lymphangiectuasia who have been treated with low fat medium chain triglyceride-supplemented diets for between 3 and 8 years (4 for longer than 5 years) is described. Though laboratory findings indicate continuing chyle leak, evidence for long-term benefit from ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.50.4.269
更新日期:1975-04-01 00:00:00
abstract:BACKGROUND:Most children with daytime wetting have detrusor instability. A minority have neuropathic vesicourethral dysfunction. The commonest cause is spina bifida, which may be closed. Clinical features suggestive of closed spina bifida include cutaneous, neuro-orthopaedic or lumbosacral spine x ray abnormalities, im...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.87.2.151
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:To examine whether behavioural or cognitive sequelae of otitis media with effusion (OME) continue into late childhood and the early teens (11-18 years). SETTING:Data from a large multipurpose birth cohort study: the Dunedin multidisciplinary health and development study. PARTICIPANTS:Around 1000 children fr...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.85.2.91
更新日期:2001-08-01 00:00:00
abstract::When isolated from the female genital tract, diphtheroids are usually regarded as commensal organisms. Corynebacterium kutscheri however is a pathogen in laboratory rodents. We report a case in which C. kutscheri was isolated as a pure culture from the umbilical cord and from other surface sites in an infant. Histolog...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.9.710
更新日期:1979-09-01 00:00:00
abstract:AIMS:To investigate whether infants who died of SIDS were more likely to have higher acute and lifetime average exposures to outdoor carbon monoxide (CO) and nitrogen dioxide (NO2) than comparison healthy infants. METHODS:A total of 169 case and 169 matched control infants born between 1988 and 1992, were studied. CO ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2004.057091
更新日期:2005-07-01 00:00:00
abstract::Metabolites of vitamin D were measured in plasma from 83 patients with idiopathic infantile hypercalcaemia syndrome who were mentally handicapped but had normal calcium values at the time of the study. No significant difference was detected in the mean plasma concentrations of 25-hydroxyvitamin D2, 1,25-dihydroxyvitam...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.12.1140
更新日期:1985-12-01 00:00:00
abstract::Life was sorted. With membership of the college under my belt, and my paediatric training completed, I needed a new challenge. I decided to launch into the deep waters of qualitative research. Stepping out with some trepidation into semistructured interviews and grounded theory, I soon found that the water was neither...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.1.44
更新日期:2003-01-01 00:00:00
abstract::A children's hospital nutritional care team prospectively monitored the frequency of sepsis in central venous catheters used for administering parenteral nutrition. During an initial study period of 12 months, 26/58 (45%) of catheters were removed because of proved sepsis. The possible causes of this alarmingly high r...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.3.335
更新日期:1991-03-01 00:00:00
abstract::Four patients with salt-losing congenital adrenal hyperplasia (CAH) who had stopped mineralocorticoid therapy for several years, showed raised plasma concentrations of 17OH-progesterone and plasma renin activity, despite adequate glucoticoid therapy. One patient was able to reduce urinary sodium excretion when the sod...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.5.350
更新日期:1979-05-01 00:00:00
abstract::A modified nasopharyngeal tube is described that does not add airway dead space and resistance, is well tolerated, highly successful, and allows simultaneous use of oxygen prongs. This potentially reduces the need for surgical intervention to relieve high upper airway obstruction from Pierre-Robin syndrome and other c...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.80.2.186
更新日期:1999-02-01 00:00:00
abstract::Two cross sectional surveys, 24 years apart, using the same respiratory questionnaire, were carried out to examine changes in prevalence rates of cough, phlegm, and wheeze and to relate changes in wheeze to objective peak expiratory flow rates (PEFRs). The surveys were done in towns in southern and northern England an...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.6.729
更新日期:1993-06-01 00:00:00
abstract::In a cohort of 14 children with identical cardiac xenografts, two boys developed acute myeloid leukaemia 11 and 16 months respectively after the operation. A dedicated working group designed a scheme intending to take care of all aspects of the situation. This article focuses on preferred strategies towards patients, ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.5.435
更新日期:2003-05-01 00:00:00
abstract::The objectives of this study were to determine whether or not the probiotic Lactobacillus GG can colonise the immature bowel of premature infants and if so, does colonisation result in a reduction of the size of the bowel reservoir of nosocomial pathogens such as enterobacteriaceae, enterococci, yeasts or staphylococc...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.69.5_spec_no.483
更新日期:1993-11-01 00:00:00
abstract::All 212 neonates undergoing cardiac surgery at this hospital during the 5-year period from 1976 to 1980 inclusive were reviewed. Forty required open heart surgery with 23 (57%) deaths. One hundred and seventy-four neonates underwent non-bypass procedures and could be divided into three groups: group 1 (82 patients) ha...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.58.2.137
更新日期:1983-02-01 00:00:00
abstract::We describe a child with primary defect of polymorph bacterial killing associated with systemic lungs erythematosus. We suggest that her autoimmune disease results from chronic bacterial antigen stimulation and propose a hypothetical model linking immunodeficiency with autoimmunity. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.5.382
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVES:(1) To determine the prevalence of cough, wheeze, and breathlessness, both as single symptoms and in combination, in primary schoolchildren and their relation to doctor diagnosed asthma. (2) To identify in areas with different levels of dust pollution whether questionnaire reported 'cough alone' (without whe...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.6.489
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:To undertake a systematic review and meta-analysis to establish the effectiveness of handwashing in reducing absence and/or the spread of respiratory tract (RT) and/or gastrointestinal (GI) infection among school-aged children and/or staff in educational settings. DESIGN:Randomised-controlled trials (RCTs). ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,meta分析,评审
doi:10.1136/archdischild-2015-308875
更新日期:2016-01-01 00:00:00
abstract::Fluids used for flushing arterial catheters, bronchial lavage, and drug administration are not normally considered when assessing daily fluid intake, yet infants weighing less than 1000 g at birth gained up to 12 ml/kg/day of extra fluid and 2.4 mmol/kg/day (mean) of extra sodium from these hidden sources. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.7.695
更新日期:1986-07-01 00:00:00
abstract::A family with multiple congenital scalp defects, over two generations and probably genetically determined, is described. Although alarming in appearance, surgical intervention is not indicated at least for small lesions. The risk of haemorrhage and meningitis is emphasized. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.50.12.958
更新日期:1975-12-01 00:00:00
abstract:OBJECTIVES:To explore how parents navigate urgent and emergency care (U&EC) services when their child <5 years old has a feverish illness, their views of that experience and whether services are meeting their needs and triaging in line with national guidance. DESIGN:Parents of a febrile child <5 years old contacting a...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2010.210096
更新日期:2011-09-01 00:00:00
abstract::Fifty four of 74 paediatricians in the West Midlands (43 general medical, 11 subspecialist) replied to a postal questionnaire about their outpatient practice: 37 timed each consultation in one clinic. On average, subspecialty consultations lasted 37 minutes for new patients and 29 minutes for review. In general clinic...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.67.2.206
更新日期:1992-02-01 00:00:00
abstract::Kwashiorkor and marasmus, collectively termed severe acute malnutrition (SAM), account for at least 10% of all deaths among children under 5 years of age worldwide, virtually all of them in low-income and middle-income countries. A number of risk factors, including seasonal food insecurity, environmental enteropathy, ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2014-306026
更新日期:2015-03-01 00:00:00
abstract:AIMS:To investigate the differences in perception of quality of life between parents of chronically ill children and paediatricians at diagnosis and follow up. Quality of life was assessed using the (HUI3). METHODS:Longitudinal study (July 1999-January 2002) of 37 paediatricians and 181 parents of patients (children a...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2004.051722
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:To assess the persistence of serum Haemophilus influenzae type b antibodies and the prevalence of H influenzae type b carriage in a group of preschool age children previously vaccinated in infancy. DESIGN:Names were randomly selected from immunisation records. Families were visited on five occasions over a ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.77.6.488
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:Poor condition at birth may impact on IQ, although its effect on other measures of neurodevelopment is unclear. The authors' aim was to determine whether infants receiving resuscitation after birth have reduced scores in measures of attention, memory and language skills or the need for educational support at ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2009.176065
更新日期:2011-01-01 00:00:00
abstract:AIMS:To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS:Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.86.5.352
更新日期:2002-05-01 00:00:00
abstract::Twenty-one children who had been diagnosed as having laryngomalacia by direct laryngoscopy in infancy were reviewed 7 to 12 years later. The natural history of the disease is documented. A wide variation in the time of onset and duration of the stridor was found and there was a high incidence of feeding difficulties. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.52.3.215
更新日期:1977-03-01 00:00:00
abstract:OBJECTIVE:Risk of childhood asthma is increased in children with recurrent otitis media. This may be associated with recurrent respiratory tract infections in these children, but the role of adenoidectomy, a frequent operation during childhood, is unknown. Therefore, the role of adenoidectomy in the development of atop...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,随机对照试验
doi:10.1136/adc.2008.145664
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine the glycaemic profile of patients with cystic fibrosis using a continuous glucose monitoring system (CGMS), and to evaluate the associations of glycaemic abnormalities with sex, age, pubertal stage, CFTR gene mutations, nutritional status, lung function, oral glucose tolerance te...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2017-314250
更新日期:2018-06-01 00:00:00
abstract::The sodium intake of preschool children in their home environment was investigated and the major sources of sodium other than added table salt identified. Thirty five children from a Southampton general practice were studied. Twenty four hour urinary sodium excretion was measured as a reliable indicator of daily total...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.2.159
更新日期:1986-02-01 00:00:00