Abstract：
:A key feature of plants (as opposed to animals) is their ability to establish new organs not only during embryogenesis, but also throughout their development. A master regulator of organ initiation in plants is the phytohormone auxin. Auxin acts locally as a morphogen and is directionally transported from cell to cell by polarized auxin efflux carriers, termed PIN-FORMED (PIN) proteins. Here we report that the Arabidopsis ortholog of the yeast and mammalian vacuolar protein sorting 29 (VPS29), a member of the retromer complex, mediates the formation of new axes of development. Furthermore, we show that VPS29 is required for endosome homeostasis, PIN protein cycling, and dynamic PIN1 repolarization during development. We propose a model that links VPS29 function, PIN1 polarity, and organ initiation in plants.
journal_name
Celljournal_title
Cellauthors
Jaillais Y,Santambrogio M,Rozier F,Fobis-Loisy I,Miège C,Gaude Tdoi
10.1016/j.cell.2007.08.040subject
Has Abstractpub_date
2007-09-21 00:00:00pages
1057-70issue
6eissn
0092-8674issn
1097-4172pii
S0092-8674(07)01103-8journal_volume
130pub_type
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