Effect of age on calcification of poly(hydroxyethyl methacrylate) in animals.

abstract：:Hypertension is an important primary etiology of end-stage renal disease as well as a major factor responsible for progression of renal disease due to other causes. Multiple genetic and environmental factors are responsible for the variable prevalence of hypertension in various parts of the world. Although the frequen...

journal_title：Artificial organs

authors： El-Khashab O

更新日期：2002-09-01 00:00:00

abstract：:Lipid apheresis has developed from a heroic treatment into a routine clinical therapy and currently is the major indication for performing extracorporeal plasma therapy. Whereas it was once reserved for patients with homozygous familial hypercholesterolemia, today it has a place in the secondary prevention of severe c...

journal_title：Artificial organs

authors： Bosch T

更新日期：1996-05-01 00:00:00

abstract：:Traumatic injury is often associated with hemorrhagic shock. Liposome-encapsulated hemoglobin (LEH) is being developed as an artificial oxygen carrier to address post-hemorrhage oxygen and volume deficit. Here, we report a new composition of LEH based on the use of polyethylene glycol (PEG2K ) conjugated with nonphosp...

journal_title：Artificial organs

authors： Yadav VR,Nag O,Awasthi V

更新日期：2014-08-01 00:00:00

abstract：:An increasing amount of evidence points to cerebral embolization during cardiopulmonary bypass (CPB) as the principal etiologic factor of neurologic complications. In this study, the capability of capturing and classification of gaseous emboli and pressure drop of three different membrane oxygenators (Sorin Apex, Teru...

journal_title：Artificial organs

authors： Guan Y,Palanzo D,Kunselman A,Undar A

更新日期：2009-11-01 00:00:00

abstract：:In a calf model, 3 standard and 3 heparin coated intraaortic balloons (IAB) were inserted and left deflated in the descending aorta during 20 min to simulate balloon rupture. At the end of the experiment, the IAB were examined, and 3 samples of each were collected for scanning electron microscopy (SEM) analysis. None ...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Hayoz D,von Segesser LK

更新日期：1999-02-01 00:00:00

abstract：:To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump-left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We st...

journal_title：Artificial organs

authors： Dobsák P,Novakova M,Baba A,Vasku J,Isoyama T,Saito I,Abe Y,Chinzei T,Imachi K

更新日期：2006-06-01 00:00:00

abstract：:Visual prostheses are the focus of intensive research efforts to restore some measure of useful vision to blind or near-blind patients. The development of such technology is being guided to an extent by tools that simulate prosthesis behavior for healthy sighted subjects in order to assess system requirements and conf...

journal_title：Artificial organs

authors： Obeid I,Veraart C,Delbeke J

更新日期：2010-05-01 00:00:00

abstract：:The principle of a patient-specific immunoadsorber (PsIA) is demonstrated. Studies with model systems (HSA/anti-HSA) on immobilization, stability, and leakage form the basis for the presented fast-performance liquid chromatography (FPLC) and batch experiments, which were conducted using two different protein A adsorbe...

journal_title：Artificial organs

authors： Kunkel S,Holtz M,Grossjohann B,Schuett W,Klinkmann H,Kong D,Yamada R,Kimura H,Matic GB,Ramlow W,Boeden HF

更新日期：2002-02-01 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00

abstract：:Turbulent blood flow in medical devices contributes to blood trauma, yet the exact mechanism(s) have not been fully elucidated. Local turbulent stresses, viscous stresses, and the rate of dissipation of the turbulent kinetic energy have been proffered as hypotheses to describe and predict blood damage. In this work, s...

journal_title：Artificial organs

authors： Ozturk M,O'Rear EA,Papavassiliou DV

更新日期：2015-12-01 00:00:00

abstract：:Few instruments are currently available to test mitral valve function in an ex vivo state due to the technical difficulties involved. To investigate the native ex vivo mitral valve or prosthetic mitral valve with chordae, we developed a mitral valve adapter with an annulus suturing portion and 2 papillary muscle sutur...

journal_title：Artificial organs

authors： Katoh T,Ikeda N,Nishi K,Gohra H,Hamano K,Noda H,Fujimura Y,Esato K

更新日期：1999-10-01 00:00:00

abstract：:In transplantation surgery, extending the criteria for organ donation to include organs that may have otherwise been previously discarded has provided the impetus to improve organ preservation. The traditional method of cold static storage (CS) has been tried and tested and is suitable for organs meeting standard crit...

journal_title：Artificial organs

authors： Kumar R,Chung WY,Dennison AR,Garcea G

更新日期：2017-09-01 00:00:00

abstract：:To remove anti-DNA antibodies from a patient's plasma with systemic lupus erythematosus (SLE), a DNA immunoadsorbent was developed by covalently coupling calf thymus DNA on activated Sepharose 4FF. Sepharose 4FF was activated with 5-norbornene-2,3-dicarboximido carbonochloridate (Cl-CO-ONB), which was proven to be a v...

journal_title：Artificial organs

authors： Kong DL,Schuett W,Boeden HF,Kunkel S,Holtz M,Matic G,Yamada R,Yu YT,Klinkmann H

更新日期：2000-11-01 00:00:00

abstract：:The ventricular assist device inflow cannulation site is the primary interface between the device and the patient. Connecting these cannulae to either atria or ventricles induces major changes in flow dynamics; however, there are little data available on precise quantification of these changes. The objective of this i...

journal_title：Artificial organs

authors： Timms D,Gregory S,Hsu PL,Thomson B,Pearcy M,McNeil K,Fraser J,Steinseifer U

更新日期：2010-09-01 00:00:00

abstract：:In this proof of principle study, we investigated the effectiveness and safety of hemodynamic support with the Intra-Ventricular Membrane Pump (IVMP). The IVMP was implanted into the apex of the left ventricle. Hemodynamic assessment was performed in six ex vivo beating porcine hearts (PhysioHeart platform). The cardi...

journal_title：Artificial organs

authors： van Dort DIM,Thannhauser J,Gommans FDH,Ten Cate TJ,Duncker DJ,Suryapranata H,Morshuis WJ,Geuzebroek GSC

更新日期：2020-12-01 00:00:00

abstract：:The accurate representation of rotary blood pumps in a numerical environment is important for meaningful investigation of pump-cardiovascular system interactions. Although numerous models for ventricular assist devices (VADs) have been developed, modeling methods for rotary total artificial hearts (rTAHs) are still re...

journal_title：Artificial organs

authors： Nestler F,Bradley AP,Wilson SJ,Timms DL

更新日期：2014-03-01 00:00:00

abstract：:Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

journal_title：Artificial organs

authors： Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

更新日期：1999-11-01 00:00:00

abstract：:This article presents computational studies on the effects of inlet guide vanes (IGVs) on the flow pattern and shear stress in a centrifugal blood pump. The effect of IGVs is to introduce a pre-swirl to fluid particles entering the impeller with the intention that the fluid particles will travel along the blade profil...

journal_title：Artificial organs

authors： Chan WK,Wong YW,Yu SC,Chua LP

更新日期：2002-06-01 00:00:00

abstract：:Veno-arterial extracorporeal membrane oxygenation (ECMO) may be implanted using peripheral ECMO (pECMO) or central ECMO (cECMO) cannulation techniques. The aim of this study was to compare the outcome between these two cannulation techniques. A retrospective study was performed at Düsseldorf University Hospital from O...

journal_title：Artificial organs

authors： Saeed D,Stosik H,Islamovic M,Albert A,Kamiya H,Maxhera B,Lichtenberg A

更新日期：2014-07-01 00:00:00

abstract：:Ventricular assist devices have been shown to be effective in advanced heart failure selected patients. They often have borderline end-organ function, what facilitates organ dysfunction. Liver failure is difficult to manage and leads to increased morbidity and mortality. We report a case of ductular cholestasis, an un...

journal_title：Artificial organs

authors： Mohedano-Gómez A,Pérez-Vela JL,Renes-Carreño E,De-Andrés CI,Corres-Peiretti MA,Arribas-López P,Gutierrez-Rodriguez J,Perales-Rodríguez-De-Viguri N

更新日期：2010-02-01 00:00:00

abstract：:In this study, a series of natural biodegradable materials in the form of chitosan (C)-alginate (A)-hyaluronate (H) complexes are evaluated as tissue-engineering scaffolds. The weight ratio of C/A is 1 : 1 or 1 : 2. Sodium hyaluronate is mixed in 2%. The complexes can be cast into films or fabricated as scaffolds. The...

journal_title：Artificial organs

authors： Hsu SH,Whu SW,Hsieh SC,Tsai CL,Chen DC,Tan TS

更新日期：2004-08-01 00:00:00

abstract：:This is a revision of the IDE Application Form, "How to Comply with the Food and Drug Administration's New 'Investigational Device Exemption (IDE)' Regulations, Including an Application Form" originally published in Artificial Organs, Volume 4, Number 4, November 1980. This publication updates the IDE application form...

journal_title：Artificial organs

authors：

更新日期：1982-02-01 00:00:00

abstract：:The use of recombinant human erythropoietin (rHuEpo) has revolutionized anemia management of early and late stages of chronic kidney disease. Darbopoietin is also now available for the treatment of anemia of chronic kidney disease. In addition, rHuEpo has been used for the treatment of anemia observed in critical illn...

journal_title：Artificial organs

authors： Liangos O,Pereira BJ,Jaber BL

更新日期：2003-09-01 00:00:00

abstract：:This work introduces a new Lagrangian strain-based model to predict the shear-induced hemolysis in biomedical devices. Current computational models for device-induced hemolysis usually utilize empirical fitting of the released free hemoglobin (Hb) in plasma from damaged red blood cells (RBCs). These empirical correlat...

journal_title：Artificial organs

authors： Nikfar M,Razizadeh M,Zhang J,Paul R,Wu ZJ,Liu Y

更新日期：2020-08-01 00:00:00

abstract：:Neurologic complications during on-pump cardiovascular surgery are often induced by mobilization of atherosclerotic plaques, which is directly related to enhanced wall shear stress. In the present study, we numerically evaluated the impact of dispersive aortic cannulas on aortic blood flow characteristics, with specia...

journal_title：Artificial organs

authors： Assmann A,Gül F,Benim AC,Joos F,Akhyari P,Lichtenberg A

更新日期：2015-03-01 00:00:00

abstract：:Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

journal_title：Artificial organs

authors： McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

更新日期：2018-02-01 00:00:00

abstract：:Hemodialysis vascular access (VA) stenosis remains a frequent complication. However, early detection is challenging and costly. The aim of this in vitro study was to assess a new detection method based on pulse pressure analysis at the hemodialysis needle. A silicon model of a radiocephalic arteriovenous fistula was b...

journal_title：Artificial organs

authors： Van Canneyt K,Planken RN,Eloot S,Segers P,Verdonck P

更新日期：2010-02-01 00:00:00

abstract：:A microcapsule suspension, a substitute for animal blood in hemolysis tests, has been developed for evaluation of the absolute hemolytic properties of circulatory artificial organs. The microcapsule suspension was made by dispersing microcapsule slurry into an ethylene glycol sodium chloride solution. The microcapsule...

journal_title：Artificial organs

authors： Maruyama O,Yamane T,Tsunemoto N,Nishida M,Tsutsui T,Jikuya T

更新日期：1999-03-01 00:00:00

abstract：:To overcome the weak mechanical properties of cell/hydrogel composites, a poly(DL-lactic-co-glycolic acid) sandwiched adipose-derived stem cell (ADSC)/fibrin construct was fabricated using a step-by-step mold/extraction method to generate the middle smooth muscle layer of natural blood vessels. A pulse bioreactor with...

journal_title：Artificial organs

authors： Wang X,Sui S

更新日期：2011-06-01 00:00:00

abstract：:Early in 1956, the first model of a biological artificial liver, using a live dog's liver incorporated in a cross-hemodialyzer, was placed in an experimental animal with portocaval encephalopathy. This "biological artificial liver," a hybrid artificial liver in the present terminology, was the first in the world. In O...

journal_title：Artificial organs

authors： Hori M

更新日期：1986-06-01 00:00:00