Abstract：
PURPOSE:The study aimed to examine the volumes of cerebellum and the brain stem in children with cerebral palsy (CP). MATERIAL AND METHODS:The present study included 21 children with spastic diplegic CP (11 girls and 10 boys). Twenty-one patients with CP were age- and gender-matched with the control patients. All subjects were free from neurological or psychiatric disease, had normal intellectual development, and their brain magnetic resonance imaging (MRI) scans were normal. MRI of forty-two patients were reviewed prospectively. RESULTS:The CP group had significantly smaller mean of the cerebellar hemispheres and the brain stem than did the control group. The cerebellar volumes were positively correlated with age of children with CP and the control group. No significant correlations between gender and the volumes of cerebellar hemispheres and the brain stem in controls and in the CP group were found. No significant correlations between asphyxia and the volumes of cerebellar hemispheres and the brain stem in the CP group were noted. Positive correlation between the cerebellum volume and IQ scores in children with CP was found. Negative relationship between the cerebellar hemispheres volume and Gross Motor Function Classification System in patients with CP was found. No significant correlation between the brain stem volume and IQ scores in the CP group was detected. CONCLUSION:Our data demonstrate that children with CP had smaller volumes of the cerebellum and the brain stem as compared to controls.
journal_name
Adv Med Scijournal_title
Advances in medical sciencesauthors
Kułak W,Sobaniec Wsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
180-2eissn
1896-1126issn
1898-4002journal_volume
52 Suppl 1pub_type
杂志文章abstract：PURPOSE:Promoter hypermethylation and reduced expression of many genes have been found in gastric cancer. DNA methyltransferases are enzymes potentially affecting promoter hypermethylation. MATERIAL AND METHODS:We analyzed proteins expression of DNA methyltransferase 1 and 3b by immunohistochemistry in 47 surgically r...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2014.10.002
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:The concentration of nucleic acids that undergo apoptosis (ssDNA) determines the actual activity of programmed cell death. ssDNA concentrations in liver tissue of patients with chronic HBV, HCV and HCV and HIV infections were assessed. The concentration of this nucleic acid was analyzed in relation to the conce...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To investigate the synergistic effects of nerve growth factor (NGF), ciliary neurotrophic factor (CNTF) and glia cell line-derived neurotrophic factor (GDNF) on survival and growth of sensory neurons and motoneurons, as well as on the functional recovery following sciatic nerve injury in rats. METHODS:Experime...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-010-0020-9
更新日期：2010-01-01 00:00:00
abstract：PURPOSE:Response to steroids is included in the diagnostic criteria for IgG4-related sclerosing cholangitis (IgG4-SC). To assess how to appropriately conduct steroid trials for IgG4-related SC, we examined the clinical pictures of steroid responsiveness in IgG4-SC patients. MATERIAL AND METHODS:A total of 29 patients ...
journal_title：Advances in medical sciences
pub_type： 临床试验,杂志文章
doi：10.1016/j.advms.2015.02.006
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:Existing anti-epileptic drugs (AED) have limited efficiency in many patients, necessitating the search for alternative approaches such as stem cell therapy. We report the use of autologous patient-derived mesenchymal stem cells (MSC) as a therapeutic agent in symptomatic drug-resistant epilepsy in a Phase I ope...
journal_title：Advances in medical sciences
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.advms.2016.12.004
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:We aimed to examine the polymorphism of the promoter and exon 5 of the TNFSF11 gene and their impact on bone mineral density (BMD) and the frequency of bone fractures. TNFSF11 encodes the receptor activator of the NF-kB ligand (RANKL), a key regulator of bone metabolism and osteoporosis drug targets. BMD is an ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2020.05.001
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:Desmin regulates function of mitochondria, T-tubular system and cytosolic Ca(2+) transients. We investigated whether desmin remodeling correlates with diastolic dysfunction and whether progressive desmin abnormalities are accompanied by increasing diastolic dysfunction stages. PATIENTS AND METHODS:Eighty five ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2015.01.009
更新日期：2015-03-01 00:00:00
abstract：:Nailfold videocapillaroscopy (NVC) is one of the best diagnostic non-invasive imaging techniques to evaluate microcirculation in vivo and is increasingly employed in the field of rheumatology. Indeed, at present, the most important utility of NVC is in the identification of microvascular involvement in many rheumatic ...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.2478/v10039-008-0038-4
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:Accumulating evidence has linked long noncoding RNAs (lncRNAs) to autoimmune and inflammatory disorders. This study aimed to detect the expression levels of five lncRNAs (lnc0640, lnc3643, lnc5150, lnc7514 and lncagf) in peripheral blood mononuclear cells (PBMCs) of patients with systemic lupus erythematosus (S...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2019.08.002
更新日期：2019-09-01 00:00:00
abstract：:Idiopathic retroperitoneal fibrosis (IRF) entirely confined to the pelvic cavity is an extremely rare clinical entity. Herein, is described the case of a 36- year old male who presented with clinical and imaging manifestations of a large pelvic tumor. Exploratory laparotomy revealed a large mass in the right pelvis or...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-009-0029-0
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:To assess the prognostic significance of clinicopathological factors, especially histological parameters of new Jass classification, following sphincter-sparing total mesorectal excision (TME) for high-risk rectal cancer. MATERIAL AND METHODS:Forty-five consecutive patients treated with curative intent in 1998...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：UNLABELLED:Factors believed to affect masticatory efficiency include loss of postcanine teeth, bite force, severity of malocclusion, occlusal contact area, body size and oral motor function. THE AIM:to record if there is relationship between masticatory efficiency and the state of dentition at patients whose occlusion...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The data concerning the relation between subclinical hypothyroidism (SH) and the risk of cardiovascular disease are divergent. We aimed to assess myocardial perfusion in contrast-enhanced echocardiography and intima-media thickness (IMT) in patients with SH. MATERIAL/METHODS:Forty females with SH without sympt...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0068-9
更新日期：2013-01-01 00:00:00
abstract：:Hepatitis C virus (HCV) infection is a common problem. Combined treatment with interferon and ribavirin improved treatment efficacy, but still high percentage of infected patients has not reached virus elimination. It was found that HCV infection course, but also treatment efficacy among other things can depend on pat...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.2478/v10039-009-0002-y
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:The current study objective was to compare blood platelet indices in preterm newborns (PTN) and full term newborns (FTN). MATERIALS AND METHODS:We introduced to our study 51 PTN (25 females, 26 males) and 55 FTN (25 females, 30 males). Platelet indices were estimated in blood samples collected from the umbilic...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-009-0034-3
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:NT-proBNP and BNP concentrations in CHF correlate with NYHA class and LVEE Little research has been conducted to compare the clinical performance of these two natriuretic peptides in heterogeneous CHF population. Purpose: to evaluate and compare the clinical performance of NT-proBNP and BNP in heterogeneous gro...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:Glioblastoma is the most common and the deadliest brain cancer. The aim of this study was to analyze the impact of resveratrol and its five analogs: 3,4,4'-trimethoxy, 3,4,2'-trimethoxy, 3,4,2',4'-tetramethoxy, 3,4,2',6'-tetramethoxy and 3,4,2',4',6'-pentamethoxy-trans-stilbenes (MS) on human glioblastoma T98G ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2020.11.001
更新日期：2020-11-22 00:00:00
abstract：PURPOSE:Ulcerative colitis (UC) carries a high risk of developing colorectal cancer (CRC). FK506-binding protein 51 (FKBP51) is a key regulator of glucocorticoid resistance and inflammatory tumor microenvironment. This study aimed to investigate the role of FKBP51 in UC-CRC prognosis. MATERIALS AND METHODS:The FKBP51 ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.1016/j.advms.2021.01.003
更新日期：2021-01-15 00:00:00
abstract：PURPOSE:To compare soluble Fas, FasL and Bcl-2 in Graves' disease (GD) and Hashimoto's thyroiditis (HT) to the markers of humoral response: aTPO, aTG and aTSHR. MATERIAL AND METHODS:5 groups of subjects: 1) 14 patients with GD in euthyreosis on methimazol (euGD); 2) 20 patients with hyperthyroid GD (hrGD); 3) 15 patie...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:Behaviour of the vein thrombus is determined by the activity ratio of coagulation factors to factors of fibrinolytic system. The aim of the study is to evaluate activity of some coagulation and fibrinolytic factors in the vein thrombus. MATERIAL AND METHODS:The activity of platelets aggregating factors, tissue...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:Genetic variability of hepatitis C virus (HCV) is considered to be an important factor defining viral pathogenesis, persistence and resistance to treatment. The aim of the present study was to characterize HCV genetic heterogeneity within a hypervariable region 1 (HVR-1) before and during the early period of pe...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0024-8
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Among 264 children suspected of GERD, acid GER was confirmed in 138 children on the basis of 24-hour pH monitoring. AIMS OF THE STUDY:Comparative analysis of parameters of 24-hour intraesophageal pH monitoring with dual-channel probe (in proximal channel) in children with acid GER: primary and secondary to cow...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:In the literature, the manifestations of gastric cancer have been described based on all patients. In recent times, interest has focused on the subgroup of young patients. In the following analysis, the subgroup of young patients (< 50y) is compared with an older reference group (≥ 50y). MATERIAL AND METHODS:B...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0052-4
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Caries, a social ailment, is one of the diseases of civilization of the 20th century. In Poland, the incidence rate of caries is very high both in the young and adults. The major etiological factors of caries are: improper oral hygiene, diet based on carbohydrate-rich and highly processed food products, neglect...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:In a retrospective analysis of the prevalence of KRAS mutations in patients with advanced non-small cell lung cancer (NSCLC), we detected a unique and not earlier described case of a double combination of mutations at codons 12 and 13 of the KRAS gene in a patient with lung adenocarcinoma. MATERIAL/METHODS:To ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-012-0080-0
更新日期：2013-01-01 00:00:00
abstract：:Melanoma is a malignant tumor which is inclined to metastasize promptly into the lymphatic system and other organs such as lung, liver, brain or bone. Therefore early diagnosis remains crucial for improving clinical outcome for melanoma patients. Current chemotherapy and chemo-immunotherapy regimes have shown little c...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2014.12.002
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:HCV chronic infection still presents a very serious epidemiological and clinical problem. Apart from its cytopathic effect on liver parenchyma, its detrimental effect on lipid and carbohydrate metabolism has recently been emphasized. The aim of the study was to assess lipid and carbohydrate parameters in childr...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-011-0048-5
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:It is essential in the medical care for immunocompromised patients that the environment should create minimal infection risk. Particularly, it concerns fungal infections. Fungi belonging to the Aspergillus genus are second frequent group of nosocomial pathogens producing opportunistic infections. MATERIAL AND ...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：10.2478/v10039-010-0039-y
更新日期：2010-01-01 00:00:00
abstract：:Lung cancer causes an estimated 1.6 million deaths each year, being the leading cause of cancer-related deaths in the world. Late diagnosis and, in some cases, the high aggressiveness of the tumour result in low overall five-year survival rates of 12% among men and 7% among women. The cure is most likely in early-stag...
journal_title：Advances in medical sciences
pub_type： 杂志文章,评审
doi：10.1016/j.advms.2017.12.002
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:Urinary incontinence is a disease due to which women have suffered for many centuries. But there is some optimistic side to the problem, too; such illnesses can be treated and prevented. The aim of the work was to evaluate the frequency of occurring such cases among women and to evaluate the chosen risk factors...
journal_title：Advances in medical sciences
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
