Assembly of five bluetongue virus proteins expressed by recombinant baculoviruses: inclusion of the largest protein VP1 in the core and virus-like proteins.

Abstract:

:Bluetongue virus (BTV) VP1 protein, a component of the viral RNA-directed RNA polymerase, but not the VP4 or VP6 proteins, was specifically incorporated into baculovirus expressed BTV core-like particles (composed of VP3 and VP7) and BTV virus-like particles (composed of VP2, VP3, VP5, and VP7). The VP1 protein has been shown to be associated with subcore particles composed of VP3. The data suggest that the VP1 protein of BTV has both enzymatic and structural roles in the virus life cycle.

journal_name

Virology

journal_title

Virology

authors

Loudon PT,Roy P

doi

10.1016/0042-6822(91)90094-r

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

798-802

issue

2

eissn

0042-6822

issn

1096-0341

journal_volume

180

pub_type

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