Major histocompatibility (B) complex and sex effects on the phytohaemagglutinin wattle response.

Abstract:

:The influence of the major histocompatibility (B) complex and sex on the phytohaemagglutinin (PHA) wattle response was studied in 136 segregants (B2/B2, B2/B5 and B5/B5) of a fourth generation cross between inbred lines 6(1) and 15(1). At 6 weeks of age, chickens were injected with 100 micrograms purified PHA-P. Wattle thickness measurements were taken 4, 24, 48, 72 and 96 h after injection. Analysis of variance showed that 4 h after injection, males had a significantly higher response than females but the sex-genotype interaction was also significant. Females had higher responses than males 24 and 48 h after injection as a consequence of more rapid development and earlier resolution of the reaction in males. B2/B2 chickens had significantly lower responses than B5/B5 chickens 72 and 96 h after injection, signifying a faster late resolution phase in the B2/B2 genotype. The developmental and early resolution phases of the PHA wattle response were influenced by sex while the late resolution phase was influenced by B genotype.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Taylor RL Jr,Cotter PF,Wing TL,Briles WE

doi

10.1111/j.1365-2052.1987.tb00778.x

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

343-50

issue

4

eissn

0268-9146

issn

1365-2052

journal_volume

18

pub_type

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