Construction of a recombinant vaccinia virus expressing the Lassa virus glycoprotein gene and protection of guinea pigs from a lethal Lassa virus infection.

abstract：:To determine the evolutionary and phylodynamic history of DENV-1 in Guangdong, the strains detected between 1985 and 2015 were determined with phylogenetic and Bayesian analyses of the E gene. Three DENV-1 genotypes (I, V, and VI) were circulating in Guangdong, and genotype I was detected most frequently. The evolutio...

journal_title：Virus research

authors： Bai Z,Liu LC,Jiang L,Luo L,Feng H,Lin P,Jing Q,Xiao X,Zhou H,Su W,Cao Y,Li Y,Cao Q,Chen W,Di B,Yang Z

更新日期：2018-09-02 00:00:00

abstract：:This review describes the characterization of porcine circovirus type 2 (PCV2), the field situation of porcine circovirus-associated disease (PCVAD) and the PCV2 vaccine in Korea. PCVAD has been considered the most devastating disease in Korean livestock history since its first outbreak in 1999. Postweaning multisyste...

journal_title：Virus research

authors： Chae C

更新日期：2012-03-01 00:00:00

abstract：:Genomoviruses are circular single-stranded DNA viruses (∼2 kb in size) classified into nine genera, they are highly diverse and have been identified in a variety of samples ranging from fungi to animal sera. Here we identify five genomoviruses belonging to the Gemycircularvirus genus and one to the Gemykibivirus genus...

journal_title：Virus research

authors： Kraberger S,Hofstetter RW,Potter KA,Farkas K,Varsani A

更新日期：2018-09-02 00:00:00

abstract：:The cDNA of the nucleocapsid (core) protein of classical swine fever virus (CSFV) was generated by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into a eukaryotic expression vector. The effect of the recombinant core protein on the transcriptional regulation of cellular as well as viral promoters...

journal_title：Virus research

authors： Liu JJ,Wong ML,Chang TJ

更新日期：1998-01-01 00:00:00

abstract：:Tobacco (cv. Xanthi nn) plants were watered with allopurinol [4-hydroxypyrazolo (3,4-d) pyrimidine, HPP], a xanthine oxidoreductase (XOR) inhibitor, to investigate its effects on infection by Tobacco mosaic virus engineered to express the green fluorescent protein (TMV.GFP). TMV.GFP infection was monitored by examinat...

journal_title：Virus research

authors： Silvestri S,Murphy AM,Buonaurio R,Carr JP

更新日期：2008-11-01 00:00:00

abstract：:Genome segments 1 and 2 of human group C rotavirus 'Bristol' strain were sequenced and their gene-protein coding properties assigned. This work completed the genome sequence of a human group C rotavirus (17,910 bp) and allowed the full gene-protein coding assignment of the 11 segments of dsRNA. Gene 1 is 3309 bp in si...

journal_title：Virus research

authors： Chen Z,Lambden PR,Lau J,Caul EO,Clarke IN

更新日期：2002-02-26 00:00:00

abstract：:Transcription of human immunodeficiency virus (HIV-1) is activated by viral Tat protein which regulates HIV-long terminal repeat (LTR) transcription and elongation. HIV-1 Tat protein is a substrate for the deacetylase activity of sirtuin 1 (SIRT1). Here we investigate the signaling pathway involved in Tat-induced HIV-...

journal_title：Virus research

authors： Zhang HS,Wu MR

更新日期：2009-12-01 00:00:00

abstract：:One of the leading causes of the hand, foot and mouth disease (HFMD) is Enterovirus 71 (EV-A71), displaying symptoms such as fever and ulcers in children but some strains can produce cardiopulmonary oedema which leads to death. There is no FDA-approved vaccine for prevention of severe HFMD. The molecular determinants ...

journal_title：Virus research

authors： Yee PTI,Mohamed RAH,Ong SK,Tan KO,Poh CL

更新日期：2017-06-15 00:00:00

abstract：:The 2015 Brazilian Zika virus outbreak sparked a rapid response to control the spread of the virus. What was first understood to be a mild self-resolving infection is now linked to significant neurological defects in both neonates and adults. The WHO declared the 2016 Zika epidemic a public health emergency and issued...

journal_title：Virus research

authors： Kublin JL,Whitney JB

更新日期：2018-08-02 00:00:00

abstract：:The nature of the interaction between papillomaviruses (PV) and their infected host has led to the identification of ways in which the viral oncoproteins can transform the infected host cells into cancer cells. As viral persistence is required for malignancy, and persistence requires avoidance of immune attack by the ...

journal_title：Virus research

authors： O'Brien PM,Saveria Campo M

更新日期：2002-09-01 00:00:00

abstract：:The phylogenetic diversity of classical swine fever virus (CSFV) in China has been extensively studied previously, with the report of the classification of Chinese CSFVs into four subgroups within two of the established genotypes, but the antigenic differences amongst Chinese CSF viruses still remain unknown. To addre...

journal_title：Virus research

authors： Zhu Y,Shi Z,Drew TW,Wang Q,Qiu H,Guo H,Tu C

更新日期：2009-06-01 00:00:00

abstract：:The complete nucleotide sequence of an enterovirus 77 isolate is reported. The virus designated FR/CF496-99 (France/Clermont-Ferrand 496-1999) was recovered from the feces of a 4-year-old child hospitalized for Salmonella gastroenteritis. The virus was identified by a molecular typing assay based on the genomic sequen...

journal_title：Virus research

authors： Bailly JL,Cardoso MC,Labbé A,Peigue-Lafeuille H

更新日期：2004-02-01 00:00:00

abstract：:VP28 and VP24 are two major envelope proteins of white spot syndrome virus (WSSV). The direct interaction between VP28 and VP24 has been described in previous studies. In this study, we confirmed this interaction and mapped the interaction domains of VP28 and VP24 by constructing a series of deletion mutants. By co-im...

journal_title：Virus research

authors： Li Z,Chen W,Xu L,Li F,Yang F

更新日期：2015-03-16 00:00:00

abstract：:The cis-acting replication element (CRE) in the 2C protein coding region [CRE(2C)] of enteroviruses (EV) facilitates the addition of two uridine residues (uridylylation) onto the virus-encoded protein VPg in order for it to serve as the RNA replication primer. We demonstrated that coxsackievirus B3 (CVB3) is replicati...

journal_title：Virus research

authors： Smithee S,Tracy S,Chapman NM

更新日期：2016-07-15 00:00:00

abstract：:Marek's disease virus (MDV) is an oncogenic herpesvirus that causes a disease in chickens characterized by tumor formation and immunosuppression. In this paper, we identified differentially expressed proteins in the bursa of Fabricius of chickens infected with the highly virulent MDV strain RB1B, using two-dimensional...

journal_title：Virus research

authors： Lu Z,Qin A,Qian K,Chen X,Jin W,Zhu Y,Eltahir YM

更新日期：2010-11-01 00:00:00

abstract：:The purpose of this study was to test whether the region coding for subgroup envelope specificity was a determinant of oncogenic potential. An avian retrovirus recombinant was constructed to contain the envelope gene (env) determinant for subgroup A of an avian RNA tumor virus in one of the non-oncogenic, endogenous a...

journal_title：Virus research

authors： Wright SE,Bennett DD

更新日期：1986-11-01 00:00:00

abstract：:Non-structural protein1β (Nsp1β) of porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to be involved in suppressing the host innate immune response and mediating viral subgenomic mRNA transcription. In the present study, we have analyzed the interaction of Nsp1β of Chinese highly pathogen...

journal_title：Virus research

authors： Wang L,He Q,Gao Y,Guo X,Ge X,Zhou L,Yang H

更新日期：2012-10-01 00:00:00

abstract：:Mouse Hepatitis Virus (MHV) is a single-stranded positive sense RNA virus with the ability to promote acute and chronic diseases in mice. The MHV spike protein (S) is a major virulence determinant which in addition to binding to cellular receptors to mediate cell entry and facilitate virus spread to adjacent cells by ...

journal_title：Virus research

authors： Kaufman G,Liu P,Leibowitz JL

更新日期：2014-08-30 00:00:00

abstract：:To gain more insights into the epidemiology of hantaviruses in China, the hantaviral S, M and L segment sequences were recovered from two Microtus fortis captured in Shenyang and four M. fortis trapped in Yuanjiang in China. Genetic analysis revealed that Shenyang sequences are closely related to the sequences of Fuso...

journal_title：Virus research

authors： Zou Y,Xiao QY,Dong X,Lv W,Zhang SP,Li MH,Plyusnin A,Zhang YZ

更新日期：2008-10-01 00:00:00

abstract：:Felid herpesvirus 1 (FHV-1) mutants were constructed using two-step Red-mediated recombination techniques based on a virulent full-length FHV-1 BAC clone. The individual mutant viruses generated were deficient in glycoprotein C (gC), glycoprotein E (gE), US3 serine/threonine protein kinase (PK), or both gE and thymidi...

journal_title：Virus research

authors： Tai SH,Holz C,Engstrom MD,Cheng HH,Maes RK

更新日期：2016-08-02 00:00:00

abstract：:To investigate the evolutionary origins of proteins encoded by the Poxviridae family of viruses, we examined all poxvirus protein coding genes using a method of characterizing and visualizing the similarity between these proteins and taxonomic subsets of proteins in GenBank. Our analysis divides poxvirus proteins into...

journal_title：Virus research

authors： Odom MR,Hendrickson RC,Lefkowitz EJ

更新日期：2009-09-01 00:00:00

abstract：:The sub-cellular location and mechanism of membrane association of NS3 and NS2-3 polypeptides of bovine viral diarrhoea virus (BVDV) have been examined. Both NS3 and NS2-3 proteins were detected in post-nuclear membrane fractions but not in cytosolic fractions of BVDV infected cells; a proportion of NS3, but not NS2-3...

journal_title：Virus research

authors： Zhang G,Flick-Smith H,McCauley JW

更新日期：2003-11-01 00:00:00

abstract：:Human papillomavirus (HPV) infection leads to aneuploidy, a numerical chromosomal aberration that is caused by dysregulation of chromosomal segregation. We previously found that the E7 proteins of high-risk HPVs, but not of low-risk HPVs, could bind to centromere protein-C (CENP-C). In this study, we first found that ...

journal_title：Virus research

authors： Yaginuma Y,Yoshimoto M,Eguchi A,Tokuda A,Takahashi S

更新日期：2015-07-02 00:00:00

abstract：:Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV). All PPVs are known to be zoonotic, leading to cir...

journal_title：Virus research

authors： Friederichs S,Krebs S,Blum H,Wolf E,Lang H,von Buttlar H,Büttner M

更新日期：2014-03-06 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSE) are a heterogeneous group of neurodegenerative disorders. The common feature of these diseases is the pathological conversion of the normal cellular prion protein (PrP(C)) into a β-structure-rich conformer-termed PrP(Sc). The latter can induce a self-perpetuating process...

journal_title：Virus research

authors： Le NT,Narkiewicz J,Aulić S,Salzano G,Tran HT,Scaini D,Moda F,Giachin G,Legname G

更新日期：2015-09-02 00:00:00

abstract：:To model HCV resistance to a treatment with interferon-alpha (IFN-alpha) and ribavirin, Huh7 cells, bearing HCV subgenomic replicons, were treated with these compounds for several weeks. Analysis of the cell clones, which were able to support replication of HCV RNA in the presence of high concentrations of these antiv...

journal_title：Virus research

authors： Aus dem Siepen M,Oniangue-Ndza C,Wiese M,Ross S,Roggendorf M,Viazov S

更新日期：2007-04-01 00:00:00

abstract：:Primers corresponding to conserved regions in the RNA-dependent RNA polymerase and the RACE procedure led to the cloning of the complete sweetpotato mild mottle virus (SPMMV) RNA genome. The assembled SPMMV genomic sequence was 10,818 nucleotides in length with a polyadenylated tract at the 3' terminus. The structure ...

journal_title：Virus research

authors： Colinet D,Kummert J,Lepoivre P

更新日期：1998-02-01 00:00:00

abstract：:This report provides evidence for the replication of varicella zoster virus (VZV) in Raji cells. Infection was achieved by co-cultivation of Raji cells with VZV-infected human fibroblasts. Replication of VZV, as assessed by immunofluorescence using monoclonal antibodies against VZV-glycoproteins, ranged from 18 to 24%...

journal_title：Virus research

authors： Cauda R,Chatterjee S,Tilden AB,Grossi CE,Whitley RJ

更新日期：1986-06-01 00:00:00

abstract：:African swine fever virus induces in Vero cells 81 acid and 14 basic polypeptides which account for most of the information content of the virus DNA. The kinetics and the cytosine arabinoside sensitivity of the synthesis of the virus-induced polypeptides showed the existence of three classes of proteins, two early and...

journal_title：Virus research

authors： Santarén JF,Viñuela E

更新日期：1986-09-01 00:00:00

abstract：:C167, a mutant derived from the XJC13 strain of Junin virus, is highly attenuated in its pathogenic properties for newborn mice. Whereas 10(2).PFU of XJC13 injected intracerebrally killed 100% of two-day-old mice, the mutant showed no detectable lethality. Survival of mice infected with C167 was associated with a redu...

journal_title：Virus research

authors： Scolaro LA,Mersich SE,Damonte EB

更新日期：1989-08-01 00:00:00