Ultrasonographic features of ovarian morphology capture nutritional and metabolic influences on the reproductive axis: implications for biomarker development in ovulatory disorders.

Abstract:

:Ultrasonographic imaging of ovarian morphology is used widely to inform reproductive health status in women. Metabolic disturbances induced by a negative energy balance (e.g. undernutrition) or positive energy balance (e.g. overnutrition, obesity) are known to drive or exacerbate reproductive dysfunction. Whether the utility of ultrasonographic metrics of ovarian morphology could be extended as biomarkers that detect and monitor the integration of metabolic and reproductive dysfunction is an emerging research area, and recent evidence is discussed. We note that unique variations in ovarian morphology emerge across the adiposity spectrum and highlight the potential for reproductive and metabolic 'tipping points' upon which such morphological variations may be detected on ultrasonography.

journal_name

Curr Opin Biotechnol

authors

Vanden Brink H,Pea J,Lujan ME

doi

10.1016/j.copbio.2020.10.008

subject

Has Abstract

pub_date

2020-11-25 00:00:00

pages

42-47

eissn

0958-1669

issn

1879-0429

pii

S0958-1669(20)30157-9

journal_volume

70

pub_type

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