In vivo infection of IgG-containing cells by Jembrana disease virus during acute infection.

abstract：:Selection of high-growth virus variants of strain B/Victoria/504/2000 by serial passage in eggs resulted in three amino acid substitutions, G141E, R162M, and D196Y, in the vicinity of the receptor-binding pocket of viral hemagglutinin. Virus variants containing the identified amino acid substitutions, individually or ...

journal_title：Virology

authors： Lugovtsev VY,Smith DF,Weir JP

更新日期：2009-11-25 00:00:00

abstract：:Human papillomavirus type 27 (HPV-27) and HPV-2c are isolates of the same virus as judged by genomic sequence identity. In a 400-bp stretch of the long control region and the E6 and L1 genes no changes were found between HPV-27 and HPV-2c whereas 55 changes were found between HPV-27 and HPV-2a. This justifies the elev...

journal_title：Virology

authors： Chan SY,Tan CH,Delius H,Bernard HU

更新日期：1994-06-01 00:00:00

abstract：:Unlike cell lines transformed with Polyomaviruses, transformants derived by focus formation or colony formation in agarose medium after transfer into rat fibroblast cells (FR3T3 line) of Bovine Papilloma Type 1 (BPV1) DNA were consistently observed to grow poorly in suspension and to remain highly serum dependent for ...

journal_title：Virology

authors： Grisoni M,Meneguzzi G,de Lapeyrière O,Binétruy B,Rassoulzadegan M,Cuzin F

更新日期：1984-06-01 00:00:00

abstract：:Cauliflower mosaic virus (CaMV) strains CM1841 and W260 produced markedly different symptoms when inoculated onto turnips (Brassica campestris L. 'Just Right'). The CM1841 strain induced a mild degree of stunting of infected plants while strain W260 caused moderate to severe stunting. Although CM1841 was significantly...

journal_title：Virology

authors： Anderson EJ,Qui SG,Schoelz JE

更新日期：1991-04-01 00:00:00

abstract：:Hepatitis B virus large surface protein has the unusual property of accumulating in a particulate form within a preGolgi compartment, leading to marked proliferation of intracellular membranes. We show here that large surface protein activates the promoters for two lipogenic genes that code for farnesyl diphosphate sy...

journal_title：Virology

authors： Foo NC,Yen TS

更新日期：2000-04-10 00:00:00

abstract：:The bipartite geminiviruses bean golden mosaic virus (BGMV), cabbage leaf curl virus (CabLCV), and tomato golden mosaic virus (TGMV) exhibit differential tissue tropism in Nicotiana benthamiana. In systemically infected leaves, BGMV remains largely confined to vascular-associated cells (phloem-limited), whereas CabLCV...

journal_title：Virology

authors： Qin Y,Petty IT

更新日期：2001-12-20 00:00:00

abstract：:We have previously cloned and analyzed the structure of a type 16 human papillomavirus (HPV16) integration in a primary cervical carcinoma tissue, M50 (Choo et al., J. Virol. 62, 1659-1666, 1988). We found that specific nucleotide sequences within the HPV16 genome influenced the genomic organization of the integrated ...

journal_title：Virology

authors： Choo KB,Lee HH,Liew LN,Chong KY,Chou HF

更新日期：1990-10-01 00:00:00

abstract：:Measles virus (MV) causes various responses including the induction of immune responses, transient immunosuppression and establishment of long-lasting immunity. To obtain a comprehensive view of the effects of MV infection on target cells, DNA microarray analyses of two different cell-types were performed. An epitheli...

journal_title：Virology

authors： Sato H,Honma R,Yoneda M,Miura R,Tsukiyama-Kohara K,Ikeda F,Seki T,Watanabe S,Kai C

更新日期：2008-06-05 00:00:00

abstract：:Transcription of the paramyxovirus RNA genome is thought to involve a sequential stop-start mechanism whereby monocistronic mRNAs are produced by polyadenylation and termination of 3' upstream gene followed by reinitiation at the downstream start site. For a number of paramyxoviruses, transcription across the M-F gene...

journal_title：Virology

authors： Rassa JC,Parks GD

更新日期：1998-08-01 00:00:00

abstract：:HPV-16 is the major causes of cervical cancer. Persistence of infection is a necessary event for progression of the infection to cancer. Among other factors, virus persistence is due the viral proteins fighting the immune response. HPV-16 E5 down-regulates MHC/HLA class I, which is much reduced on the cell surface and...

journal_title：Virology

authors： Campo MS,Graham SV,Cortese MS,Ashrafi GH,Araibi EH,Dornan ES,Miners K,Nunes C,Man S

更新日期：2010-11-10 00:00:00

abstract：:Porcine circovirus 2 (PCV2) has a major impact on the swine industry. Eight PCV2 genotypes (a-h) have been identified using capsid sequence analysis. PCV2d has been designated as the emerging genotype. The cryo-electron microscopy molecular envelope of PCV2d virus-like particles identifies differences between PCV2a, b...

journal_title：Virology

authors： Khayat R,Wen K,Alimova A,Gavrilov B,Katz A,Galarza JM,Gottlieb P

更新日期：2019-11-01 00:00:00

abstract：:Binding of simian virus 40 (SV40) large T antigen to human and calf thymus topoisomerase I (topo I) was readily detected by using modified enzyme-linked immunosorbent assays and immunoblots. In addition to WT T antigen, binding could also be readily demonstrated with T antigen fragments from the amino-terminal region ...

journal_title：Virology

authors： Simmons DT,Melendy T,Usher D,Stillman B

更新日期：1996-08-15 00:00:00

abstract：:The mechanism by which the large-size poxviruses enter animal cells is not known. In this investigation we show that acid pH treatment of wild-type vaccinia virus-infected cells triggers strong fusion of cells in culture, with an optimum at pH 4.8. We have identified the virus-induced fusion protein as a 14-kDa envelo...

journal_title：Virology

authors： Gong SC,Lai CF,Esteban M

更新日期：1990-09-01 00:00:00

abstract：:Sequence determinations of the hemagglutinin-neuraminidase (HN) glycoproteins of a temperature-sensitive mutant of Newcastle disease virus and two sequentially selected revertants had previously shown that substitution at a pair of residues, 129 and 175, resulted in a deficiency in neuraminidase (NA) activity, which w...

journal_title：Virology

authors： Sheehan JP,Iorio RM

更新日期：1992-08-01 00:00:00

abstract：:The genes of the RF strain of bovine rotavirus have been cloned into pBR 322 following the synthesis and hybridization of cDNA transcribed from both strands of in vitro polyadenylated genomic RNA. Cloned rotavirus DNAs were assigned to most of the 11 genomic RNA segments by Northern blot hybridization. The complete se...

journal_title：Virology

authors： Cohen J,Lefevre F,Estes MK,Bremont M

更新日期：1984-10-15 00:00:00

abstract：:Hepatitis B viruses replicate via reverse transcription of an RNA intermediate. This RNA pregenome serves as mRNA and is packaged into capsids and reverse transcribed. Both processes require the interaction of the viral reverse transcriptase, P protein, with the 5'-proximal epsilon-signals on the pregenome. For epsilo...

journal_title：Virology

authors： Beck J,Bartos H,Nassal M

更新日期：1997-01-20 00:00:00

abstract：:Naturally occurring mutations in Human T-cell Leukemia Virus Type 1 (HTLV-1) Tax protein lead to loss of recognition by cytotoxic T-lymphocytes. Most of these mutations also abolish or severely impair the transactivation function of Tax. Ninety percent of the rex gene, which encodes the viral regulator of mRNA splicin...

journal_title：Virology

authors： Smith RE,Niewiesk S,Booth S,Bangham CR,Daenke S

更新日期：1997-10-27 00:00:00

abstract：:Monoclonal antibodies directed against glycoprotein D of herpes simplex virus completely inhibited fusion of Vero cells infected with type 1 virus. In contrast, several monoclonal antibodies directed against other viral glycoproteins, including B, were ineffective or were only minimally inhibitory at the highest conce...

journal_title：Virology

authors： Noble AG,Lee GT,Sprague R,Parish ML,Spear PG

更新日期：1983-08-01 00:00:00

abstract：:A mutant (Tbts7) of alfalfa mosaic virus, the coat protein of which is unable to activate the viral genome (the RNA species 1, 2, and 3, which need some coat protein for infectivity) at 30 degrees , can be rescued at this temperature by adding to the inoculum wild-type RNA 3 (the genome part that contains the coat pro...

journal_title：Virology

authors： Smit CH,Jaspars EM

更新日期：1982-02-01 00:00:00

abstract：:The lentivirus caprine arthritis-encephalitis virus (CAEV) is closely related by nucleotide sequence homology to visna virus and other sheep lentiviruses and shows less similarity to the other animal and human lentiviruses. The genomic organization of CAEV is very similar to that of visna virus and the South African o...

journal_title：Virology

authors： Saltarelli M,Querat G,Konings DA,Vigne R,Clements JE

更新日期：1990-11-01 00:00:00

abstract：:A central, yet unresolved issue in the pathogenesis of HIV disease is the mechanism of antibody perturbation. In this study, HIV-specific memory B-cells were quantified in groups of infected subjects and compared with memory responses to other antigens and antibody titers. HIV-specific memory B-cell responses were vig...

journal_title：Virology

authors： Bussmann BM,Reiche S,Bieniek B,Krznaric I,Ackermann F,Jassoy C

更新日期：2010-02-05 00:00:00

abstract：:Marek' disease virus serotype-1, also know as Gallid herpesvirus 2 (GaHV-2), elicits T-cell lymphomas in chickens. The GaHV-2 genome encodes an oncoprotein, Meq, with similarity to the Jun/Fos family of proteins. We have previously shown that Meq homodimers are not sufficient to induce lymphomas in chickens. In this s...

journal_title：Virology

authors： Suchodolski PF,Izumiya Y,Lupiani B,Ajithdoss DK,Lee LF,Kung HJ,Reddy SM

更新日期：2010-04-10 00:00:00

abstract：:Flaviviruses are single-stranded positive RNA viruses that replicate through double stranded RNA (dsRNA) intermediates. These dsRNA may be recognized as pathogen-associated molecular patterns by cellular receptors including membrane-bound Toll-like receptor 3 (TLR3) and cytosolic helicases RIG-I and MDA5. dsRNA stimul...

journal_title：Virology

authors： Baronti C,Sire J,de Lamballerie X,Quérat G

更新日期：2010-09-01 00:00:00

abstract：:Monoclonal antibody 1B4, previously shown to be protective in vivo and to cross-react with both virally encoded and normal host cell proteins, was used to screen a lambda gt11 cDNA derived from mRNA harvested from mouse embryo fibroblasts 24 hr after infection with murine cytomegalovirus (MCMV). A 700-bp cDNA was iden...

journal_title：Virology

authors： Dallas PB,Lyons PA,Hudson JB,Scalzo AA,Shellam GR

更新日期：1994-05-01 00:00:00

abstract：:Long-term non-progressive HIV infection, characterized by low but detectable viral load and stable CD4 counts in the absence of antiviral therapy, is observed in about 5% of HIV-infected patients. Here we identified four therapy naïve individuals who are strongly seropositive for HIV-1 but who lack evidence of detecta...

journal_title：Virology

authors： Kloosterboer N,Groeneveld PH,Jansen CA,van der Vorst TJ,Koning F,Winkel CN,Duits AJ,Miedema F,van Baarle D,van Rij RP,Brinkman K,Schuitemaker H

更新日期：2005-08-15 00:00:00

abstract：:To investigate the mode of gene expression of red clover mottle virus (RCMV) middle component (M) RNA, we have synthesized an oligopeptide corresponding to the predicted carboxy-terminus of the RCMV counterparts of the cowpea mosaic virus (CPMV) 48K and 58K proteins. Using an antiserum raised against this synthetic ol...

journal_title：Virology

authors： Shanks M,Tomenius K,Clapham D,Huskisson NS,Barker PJ,Wilson IG,Maule AJ,Lomonossoff GP

更新日期：1989-12-01 00:00:00

abstract：:Autophagy is a cellular response against stresses which include the infection of viruses and bacteria. We unravel that Dengue virus-2 (DV2) can trigger autophagic process in various infected cell lines demonstrated by GFP-LC3 dot formation and increased LC3-II formation. Autophagosome formation was also observed under...

journal_title：Virology

authors： Lee YR,Lei HY,Liu MT,Wang JR,Chen SH,Jiang-Shieh YF,Lin YS,Yeh TM,Liu CC,Liu HS

更新日期：2008-05-10 00:00:00

abstract：:Prior studies with recombinant viruses constructed in vitro showed that the V2 domain of envelope gp120, in addition to the required V3 domain, enhances the efficiency of infection of primary macrophages by HIV-1. Present structural studies on the gp120s of these recombinant viruses using three human monoclonal antibo...

journal_title：Virology

authors： Koito A,Stamatatos L,Cheng-Mayer C

更新日期：1995-02-01 00:00:00

abstract：:Temperate coliphage P2 integrates its genome into the host chromosome upon lysogenization via a site-specific recombination event mediated by an integrase belonging to the complex family of tyrosine recombinases. The host integration site attB (BOB') is localized in the end of the cyaR gene and shares 27 nucleotides w...

journal_title：Virology

authors： Sylwan L,Frumerie C,Haggård-Ljungquist E

更新日期：2010-09-01 00:00:00

abstract：:The post-entry events of HIV-1 infection occur within reverse transcription complexes derived from the viral cores entering the target cell. HIV-1 cores contain host proteins incorporated from virus-producing cells. In this report, we show that MCM5, a subunit of the hexameric minichromosome maintenance (MCM) DNA heli...

journal_title：Virology

authors： Santos S,Obukhov Y,Nekhai S,Pushkarsky T,Brichacek B,Bukrinsky M,Iordanskiy S

更新日期：2016-10-01 00:00:00