Abstract:
:Much of the Y chromosome consists of large palindromic arrays harboring genes that are critical for spermatogenesis. In this issue, Lange et al. (2009) show that although gene conversion within these arrays maintains their integrity, it also permits rare unequal sister chromatid-exchange events within palindromes that create unstable dicentric chromosomes, resulting in infertility, sex reversal, and Turner syndrome.
journal_name
Celljournal_title
Cellauthors
Hall HE,Hawley RSdoi
10.1016/j.cell.2009.08.022subject
Has Abstractpub_date
2009-09-04 00:00:00pages
830-2issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(09)01039-3journal_volume
138pub_type
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