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Probing the Diversity of T Cell Dysfunction in Cancer.

Abstract：

:T cell dysfunction in cancer comes in many forms, with two new varieties reported in this issue. Daley et al. find that T cells expressing γδ T cell receptors (TCR) promote pancreatic tumor growth by inhibiting activation of T cells with conventional TCRs. Singer et al. characterize dysfunctional tumor infiltrating lymphocytes to reveal a role for zinc homeostasis in anti-tumor immunity.

journal_name

Cell

journal_title

Cell

authors

Sowell RT,Kaech SM

doi

10.1016/j.cell.2016.08.058

subject

Has Abstract

pub_date

2016-09-08 00:00:00

pages

1362-1364

issue

6

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(16)31155-2

journal_volume

166

pub_type

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