Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification.

abstract：:A study of crepuscular and night-biting mosquitoes was conducted at remote settlements along the Padauiri River, middle Negro River, state of Amazonas, Brazil. Collections were performed with human bait and a CDC-light trap on three consecutive days per month from June 2003-May 2004. In total, 1,203 h of collection we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Suárez-Mutis MC,Fé NF,Alecrim W,Coura JR

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease. Although there is some evidence for the beneficial effect of bone marrow-derived cells in chagasic disease, the mechanisms underlying their effects i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Irion CI,Paredes BD,Brasil GV,Cunha STD,Paula LF,Carvalho AR,Carvalho ACC,Carvalho AB,Goldenberg RCDS

更新日期：2017-08-01 00:00:00

abstract：:Multi-resistant gram-negative rods are important pathogens in intensive care units (ICU), cause high rates of mortality, and need infection control measures to avoid spread to another patients. This study was undertaken prospectively with all of the patients hospitalized at ICU, Anesthesiology of the Hospital São Paul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins ST,Moreira M,Furtado GH,Marino CG,Machado FR,Wey SB,Medeiros EA

更新日期：2004-05-01 00:00:00

abstract：:Prosorhynchoides arcuatus (Linton, 1900) from the intestine of Pomatomus saltator (L.) from the Atlantic coast of the State of Rio de Janeiro is studied by scanning electron microscopy, with detailed description of tegumental spines. Comments on the synonymy of this species with Bucephalopsis callicotyle Kohn, 1962 ar...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cohen SC,Kohn A,Barth OM

更新日期：1995-01-01 00:00:00

abstract：:In Brazil, until 2004, the immunization policy against diphtheria involved childhood vaccination with no official routine booster dose administered after 15 years of age. This study assessed functional antibody levels against diphtheria among blood donors. A total of 140 blood samples were collected, and diphtheria an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pimenta FP,Damasco PV,Cerbino Neto J,Lopes GS,Hirata R Jr,Milagres LG,Mattos-Guaraldi AL

更新日期：2006-06-01 00:00:00

abstract：:The main purpose of the present study was to examine if there is difference in terms of incidence rates of congenital toxoplasmosis among populations assisted in public and private hospitals from Uberlândia, state of Minas Gerais, Brazil. A total of 805 serum samples from cord blood were collected, being 500 from publ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Segundo GR,Silva DA,Mineo JR,Ferreira MS

更新日期：2004-02-01 00:00:00

abstract：:Coagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections cause...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cunha Mde L,Rugolo LM,Lopes CA

更新日期：2006-09-01 00:00:00

abstract：:Investigation of the aetiology of viral meningitis in Brazil is most often restricted to cases that occur in the Southern and Southeastern Regions; therefore, the purpose of this study is to describe the viral meningitis cases that occurred in state of Pará, Northern Brazil, from January 2005-December 2006. The detect...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Castro CM,Oliveira DS,Macedo O,Lima MJ,Santana MB,Wanzeller AL,Silveira Ed,Gomes Mde L

更新日期：2009-05-01 00:00:00

abstract：:Studies on the sandfly fauna to evaluate natural infection indexes are still limited in the Brazilian Amazon, a region with an increasing incidence of cutaneous leishmaniasis. Here, by using a multiplex polymerase chain reaction directed to Leishmania kDNA and hybridisation, we were able to identify L. (Viannia) subge...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Araujo-Pereira T,Pita-Pereira D,Boité MC,Melo M,Costa-Rego TA,Fuzari AA,Brazil RP,Britto C

更新日期：2017-01-01 00:00:00

abstract：:The ecology of phlebotomine sandflies in an endemic focus of cutaneous leishmaniasis in Northern Venezuela (San Esteban, Carabobo State) was investigated through a year-term study. Three different habitats: viz. a house, a peridomestic area and a sylvatic area, were covered and the species composition, the abundance a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feliciangeli MD

更新日期：1987-01-01 00:00:00

abstract：:Granuloma size is the variable most frequently used to evaluate the immunopathogenesis of schistosome infections. However, hepatic fibrosis is at the least an equally relevant variable. Hepatic fibrosis and the size of circumoval granulomas are frequently dissociated in experimental murine Schistosoma mansoni and S. j...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cheever AW

更新日期：1997-09-01 00:00:00

abstract：:A new species of the genus Cotylophoron (Trematoda--Paramphistomidae) --Cotylophoron travassosi sp. n.--is described. The measurements of the worm and its structures are compared with the valid known species. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Costa HM,Guimaráes MP

更新日期：1992-01-01 00:00:00

abstract：:Integration of human papillomavirus (HPV) DNA into human cells accompanied by the disruption of the viral genome has been described as a prerequisite for cancer development. This study aimed to investigate E2 gene integrity of HPV16 and HPV58 viruses isolated from infected women with cervical lesions. Forty-two HPV16-...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： González-Losa MD,Puerto-Solis M,Tenorio Ruiz J,Rosado-López AI,Hau-Aviles O,Ayora-Talavera G,Cisneros-Cutz I,Conde-Ferráez L

更新日期：2016-12-01 00:00:00

abstract：:The leishmanicidal activity of four batches of meglumine antimoniate, produced in Farmanguinhos-Fiocruz, Brazil (TAMs), was assessed and compared to Glucantime-Aventis Pharma Ltda. Using the amastigote-like in vitro model, the active concentrations of Sb v varied from 10microg/ml to 300microg/ml for L. (L.) chagasi an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morais-Teixeira Ed,Carvalho AS,Costa JC,Duarte SL,Mendonça JS,Boechat N,Rabello A

更新日期：2008-06-01 00:00:00

abstract：:The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors. Using affinity columns with G-actin and F-actin we isolated actin binding proteins from the parasite. By immunoblottin...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Forero C,Wasserman M

更新日期：2000-05-01 00:00:00

abstract：:Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to possess indole alkaloids and other classes of secondary metabolites, whereas terpenoids, an inositol and the indole alkaloids harmane-3 acid and braznitidumine...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coutinho JP,Aguiar AC,dos Santos PA,Lima JC,Rocha MG,Zani CL,Alves TM,Santana AE,Pereira Mde M,Krettli AU

更新日期：2013-12-01 00:00:00

abstract：:Aspartyl proteases are a class of enzymes that include the yeast aspartyl proteases and secreted aspartyl protease (Sap) superfamilies. Several Sap superfamily members have been demonstrated or suggested as virulence factors in opportunistic pathogens of the genus Candida. Candida albicans, Candida tropicalis, Candida...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Parra-Ortega B,Cruz-Torres H,Villa-Tanaca L,Hernández-Rodríguez C

更新日期：2009-05-01 00:00:00

abstract：:Angiostrongylus costaricensis lives in the cecal and mesenteric arteries of its vertebrate hosts, and causes an inflammatory disease in humans. To investigate unknown aspects of the abdominal angiostrogyliasis pathogenesis, infected Sigmodon hispidus were sequentially studied in different times of infection. The study...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mota EM,Lenzi HL

更新日期：2005-07-01 00:00:00

abstract：:BACKGROUND Studies on malaria vectors in the Pantanal biome, Central Brazil, were conducted more than half a century ago. OBJECTIVES To update anopheline records and assess receptivity and vulnerability to malaria transmission. METHODS Five-day anopheline collections were conducted bimonthly in Salobra, Mato Grosso do...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Marinho-E-Silva M,Sallum MAM,Rosa-Freitas MG,Lourenço-de-Oliveira R,Silva-do-Nascimento TF

更新日期：2018-02-01 00:00:00

abstract：:India was affected by a major outbreak of chikungunya fever caused by Chikungunya virus (CHIKV) during 2006-2007. Kerala was the worst affected state during 2007 with a contribution of 55.8% suspected cases in the country. However, except for clinically reported case records, no systematic information is available on ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kumar NP,Suresh A,Vanamail P,Sabesan S,Krishnamoorthy KG,Mathew J,Jose VT,Jambulingam P

更新日期：2011-12-01 00:00:00

abstract：:Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed. Dual infection by DENV-2 and DENV-3 was identified by type-specific indirect immunofluorescence assay and confirmed by reverse transcription polymerase chain rea...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Araújo FM,Nogueira RM,de Araújo JM,Ramalho IL,Roriz ML,de Melo ME,Coelho IC

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Occult hepatitis B virus (HBV) - characterized by the absence of detectable HBsAg in the presence of HBV DNA - represents a potential threat for blood safety. OBJECTIVES:This study was conducted with the aim to investigate the serological and molecular characterization of occult HBV infection (OBI) among bl...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mabunda N,Zicai AF,Ismael N,Vubil A,Mello F,Blackard JT,Lago B,Duarte V,Moraes M,Lewis L,Jani I

更新日期：2020-09-23 00:00:00

abstract：:The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fidelis TAA,Brasileiro-Filho G,Santos HH,Vasconcelos-Santos DV,Parreiras PM,Coelho PMZ,Araujo N,Chaud MV,Lambertucci JR

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Lutzomyia umbratilis, the vector for Leishmania guyanensis in northern South America, has been found naturally infected with L. guyanensis only in areas north of the Negro and Amazon rivers. While populations of this sand fly species are also found in areas south of these rivers, these populations have never...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Soares RP,Nogueira PM,Secundino NF,Marialva EF,Ríos-Velásquez CM,Pessoa FAC

更新日期：2018-03-01 00:00:00

abstract：:As pyrethroids are presently the favored group of insecticides to control triatomines, we performed a series of bioassays to determine the intrinsic activity of some of the main compounds used in the control campaigns, against five of the main species of triatomines to be controlled. Comparing the insecticides it can ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira Filho AM

更新日期：1999-01-01 00:00:00

abstract：:In order to determine the best type of rabies vaccine to use as a booster, 78 serological samples from singly vaccinated cattle were analyzed by counterimmunoelectrophoresis technique. The animals were divided into several groups, received the first vaccine dose with modified live virus vaccine (ERA strain) and were r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira AN,Andrade MC,Silva MV,Moura WC,Cortez Contreiras E

更新日期：2000-01-01 00:00:00

abstract：:Twenty six coprolites from an archaeological site in the province of Iquique, northern Chile, were examined for parasites. Coprolites were found in two excavation units, I and II (Tiliviche site), dated respectively at 5,900 B.C. to 4,110 B.C. and 4,110 B.C. to 1,950 B.C., and identified as of human origin. Only at th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira LF,de Araújo AJ,Confalonieri UE,Nuñez L

更新日期：1984-04-01 00:00:00

abstract：:A comparative study was undertaken on the immunogenic properties of 63kDa glycoproteins obtained from five different strains/species of Leishmania and assessed in C57BL/10 mice. The humoral immune response was assessed by ELISA against the five different antigens of the immunized animals. The cellular immune response ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dabés Guimarães TM,de Toledo VD,da Costa CA,da Costa RT,Genaro O,Williams P,Mayrink W

更新日期：1996-01-01 00:00:00

abstract：:We investigated the cytokine profile of peripheral mononuclear cells from chronic osteomyelitis (OST) patients following in vitro stimulation with staphylococcal enterotoxin A (SEA). We demonstrate that stimulation with SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-α, i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira GF,Moraes C,Silveira AM,Correa-Oliveira R,Teixeira-Carvalho A,Martins-Filho OA,Moreno EC,do Carmo LS,Fraga LA,Malaquias LC

更新日期：2012-05-01 00:00:00

abstract：:Hepatitis B virus (HBV) has a low endemicity in Rio de Janeiro, Brazil. Sexual transmission must play an important role in this virus, but the prevalence and risk factors have never been properly investigated. The aim of this paper is to determine the prevalence and risk factors for HBV infection in patients attending...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira LH,Silva IR,Xavier BL,Cavalcanti SM

更新日期：2001-07-01 00:00:00