In vitro and in vivo activity of meglumine antimoniate produced at Farmanguinhos-Fiocruz, Brazil, against Leishmania (Leishmania) amazonensis, L (L.) chagasi and L (Viannia) braziliensis.

abstract：:We analyzed prospectively 326 laboratory-confirmed, uncomplicated malarial infections (46.3% due to Plasmodium vivax, 35.3% due to P. falciparum, and 18.4% mixed-species infections) diagnosed in 162 rural Amazonians aged 5-73 years. Thirteen symptoms (fever, chills, sweating, headache, myalgia, arthralgia, abdominal p...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva-Nunes M,Ferreira MU

更新日期：2007-06-01 00:00:00

abstract：:A comparative study was undertaken on the immunogenic properties of 63kDa glycoproteins obtained from five different strains/species of Leishmania and assessed in C57BL/10 mice. The humoral immune response was assessed by ELISA against the five different antigens of the immunized animals. The cellular immune response ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dabés Guimarães TM,de Toledo VD,da Costa CA,da Costa RT,Genaro O,Williams P,Mayrink W

更新日期：1996-01-01 00:00:00

abstract：:After the acute hyperergic phase of schistosomal infection, the chronic phase of the disease corresponds to the establishment of a relative equilibrium between the host and the parasite. This involves: (1) A shift from the predominance of the TH2 response observed in the acute phase, to the predominance of the TH1 res...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Borojevic R

更新日期：1992-01-01 00:00:00

abstract：:Although human T-lymphotropic virus type I (HTLV-I) exhibits high genetic stability, as compared to other RNA viruses and particularly to human immunodeficiency virus (HIV), genotypic subtypes of this human retrovirus have been characterized in isolates from diverse geographical areas. These are currently believed not...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Segurado AA,Biasutti C,Zeigler R,Rodrigues C,Damas CD,Jorge ML,Marchiori PE

更新日期：2002-04-01 00:00:00

abstract：:Investigation of the aetiology of viral meningitis in Brazil is most often restricted to cases that occur in the Southern and Southeastern Regions; therefore, the purpose of this study is to describe the viral meningitis cases that occurred in state of Pará, Northern Brazil, from January 2005-December 2006. The detect...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Castro CM,Oliveira DS,Macedo O,Lima MJ,Santana MB,Wanzeller AL,Silveira Ed,Gomes Mde L

更新日期：2009-05-01 00:00:00

abstract：:This is the first report on occurrence of Biomphalaria straminea in the district of São José de Almeida (municipality of Jaboticatubas) State of Minas Gerais, Brazil. The presence of B. glabrata and B. tenagophila had already been reported in this area. Such municipality is part of the metropolitan region of Belo Hori...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Massara CL,Carvalho Odos S,Caldeira RL,Jannotti-Passos LK,Schall VT

更新日期：2002-01-01 00:00:00

abstract：:Distinct Toxoplasma gondii antigens were entrapped within liposomes and evaluated for their ability to protect Balb/c mice against congenital transmission: soluble tachyzoite antigen (L/STAg), soluble tissue cyst antigen (L/SCAg), soluble tachyzoite plus tissue cyst (L/STCAg) or purified 32kDa antigen of tachyzoite (L...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Elsaid MM,Martins MS,Frézard F,Braga EM,Vitor RW

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Biomphalaria glabrata snails are widely distributed in schistosomiasis endemic areas like America and Caribe, displaying high susceptibility to infection by Schistosoma mansoni. After the availability of B. glabrata genome and transcriptome data, studies focusing on genetic markers and small non-coding RNAs ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Queiroz FR,Portilho LG,Jeremias WJ,Babá ÉH,do Amaral LR,Silva LM,Coelho PMZ,Caldeira RL,Gomes MS

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES:We sought to identify the viral etiology of equine encephalitis in Espírito Santo state. METHODS:We performed...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins LC,Silva EVPD,Casseb LMN,Silva SPD,Cruz ACR,Pantoja JAS,Medeiros DBA,Martins Filho AJ,Cruz EDRMD,Araújo MTF,Cardoso JF,Cunha MACRD,Almada GL,Romano APM,Santos MGDP,Rodrigues GAP,Chiang JO,Quaresma JAS,Carvalho

更新日期：2019-01-17 00:00:00

abstract：:This study had the objective of to analyze the demographic and bacteriologic data of 32 hospitalized newborns in an neonatal intensive care unit of a public maternity hospital in Rio de Janeiro city, Brazil, seized by Pseudomonas aeruginosa sepsis during a period ranged from July 1997 to July 1999, and to determine th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Loureiro MM,de Moraes BA,Mendonca VL,Quadra MR,Pinheiro GS,Asensi MD

更新日期：2002-04-01 00:00:00

abstract：:An experimental model for acquired and congenital ocular toxoplasmosis as well as a model to induce experimental autoimmune uveitis (EAU) was investigated in Calomys callosus. Toxoplasma gondii, ME-49 strain, was used to infect males and pregnant- and not pregnant-females while S-antigen, a major glycoprotein of the r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pereira Mde F,Silva DA,Ferro EA,Mineo JR

更新日期：1999-01-01 00:00:00

abstract：:Scientists have increasingly recognised that low methodological and analytical rigour combined with publish-or-perish incentives can make the published scientific literature unreliable. As a response to this, large-scale systematic replications of the literature have emerged as a way to assess the problem empirically....

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Neves K,Carneiro CF,Wasilewska-Sampaio AP,Abreu M,Valério-Gomes B,Tan PB,Amaral OB

更新日期：2020-10-23 00:00:00

abstract：:This is the first report of adult and nymphs (20 nymphs of all stages and 4 adults) of Microtriatoma trinidadensis (Lent 1951) (Hemiptera: Reduviidae: Triatominae) collected in peridomestic environment, in the department of La Paz, Bolivia. These specimens were associated to Rhodnius stali Lent, Jurberg & Galvão 1993....

journal_title：Memorias do Instituto Oswaldo Cruz

authors： De la Riva J,Matias A,Torrez M,Martínez E,Dujardin JP

更新日期：2001-10-01 00:00:00

abstract：:Citral, the main constituent of lemongrass (Cymbopogon citratus) essential oil, was added to Trypanosoma cruzi cultures grown in TAU3AAG medium to observe the effect on the epimastigote-to-trypomastigote differentiation process (metacyclogenesis). Our results showed that citral (20 μg/mL) did not affect epimastigote v...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardoso J,Soares MJ

更新日期：2010-12-01 00:00:00

abstract：:Brazilian studies involving entomological succession patterns in carcasses have been used to describe the necrophagous entomofauna of a determined municipality or region with forensic objectives. Following the same objectives, an ecological study with 10 calyptrate dipterans was carried out during the winter of 2007 a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa RR,Mello-Patiu CA,Ururahy-Rodrigues A,Barbosa CG,Queiroz MM

更新日期：2010-03-01 00:00:00

abstract：:The triatomine bug Triatoma infestans probably originated in Bolivia and dispersed passively over wide areas of South America, where it is the principal vector of Trypanosoma cruzi. In the region of its probable origin this species shows colonization in two different ecotopes, so that it may be encountered in sylvatic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pires HH,Barbosa SE,Diotaiuti L

更新日期：2000-11-01 00:00:00

abstract：:In laboratory trials an aqueous solution of Piquerol A from Piqueria trinervia, collected in several regions of Mexico, showed a molluscicide action on the adults of eight different pulmonates snails species: Fossaria (Fossaria) humilis, F. (Bakerilymnaea) sp., Pseudosuccinea columella and Stagnicola attenuata from Me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cruz-Reyes A,Chavarin C,Campos Arias MP,Taboada J,Jimenez M

更新日期：1989-01-01 00:00:00

abstract：:Lutzomyia (Lutzomyia) cruzi has been named as a probable vector of Leishmania chagasi in Corumbá, Mato Grosso do Sul, Brazil. Taxonomically L. cruzi is closely related to the L. longipalpis species complex. Females of L. cruzi and L. longipalpis are morphologically indistinguishable and associated males must be examin...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brazil RP,Hamilton JG

更新日期：2002-04-01 00:00:00

abstract：:The population biology of three populations of Panstrongylus megistus was compared to determine possible influence on the behaviour and epidemiological importance of this species. The results demonstrated differences in terms of egg eclosion time, nymphal mortality and development rates, and feeding and defaecation ra...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barbosa SE,Soares RP,Pires HH,Diotaiuti L

更新日期：2001-08-01 00:00:00

abstract：:Given their medical and veterinary relevance, the members of the Pipiens Assemblage are a worldwide target of ecological research. The distribution of Culex pipiens s.s. and Cx. quinquefasciatus converge in Buenos Aires, Argentina, where hybrids have been detected. Each member of the assemblage exhibits a distinct eco...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardo MV,Rubio A,Junges M,Vezzani D,Carbajo AE

更新日期：2016-11-01 00:00:00

abstract：:Morphometrics of Brazilian strains (BH, SJ and CMO) of Schistosoma mansoni cercariae were obtained with a computerized image analyzer (IMAGE PRO PLUS, MEDIA CYBERNETICS), considering the following characters: body area, tail, furcae, oral and ventral suckers and distance between them. For statistical analysis, the var...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Machado-Silva JR,da Silva CH,Pereira MJ,de Oliveira RM,Pinto RM,Gomes DC

更新日期：2000-11-01 00:00:00

abstract：:A simple and rapid method for differentiating the sibling species Biomphalaria tenagophila and Biomphalaria occidentalis by agarose gel electrophoresis (AGE) is described. Snail hemolymph is used as the test sample and the red coloration of the hemoglobin fraction permits visualization of the migration patterns withou...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bailey JB,Michelson EH,Paraense WL

更新日期：1986-07-01 00:00:00

abstract：:Mycobacterium fortuitum is a rapidly growing nontuberculous Mycobacterium that can cause a range of diseases in humans. Complications from M. fortuitum infection have been associated with numerous surgical procedures. A protective immune response against pathogenic mycobacterial infections is dependent on the granulom...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva TR,Petersen AL,Santos Tde A,Almeida TF,Freitas LA,Veras PS

更新日期：2010-08-01 00:00:00

abstract：:The aim of this study was to test if serological distinction between patients with active and inactive neurocysticercosis (NCC), could be accomplished by the recognition of immunodominant peptides in total saline antigenic extract of Taenia solium metacestodes by IgG antibody in cerebrospinal fluid (CSF) and serum pai...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Barcelos IS,Moura LP,Costa VP,Ferreira MS,Costa-Cruz JM

更新日期：2007-09-01 00:00:00

abstract：:The ultrastructure of endogenous stages of Eimeria ninakohlyakimovae was observed in epithelial cells of cecum and colon crypts from a goat experimentally infected with 2.0 x 10(5) oocysts/kg. The secondary meronts developed above the nucleus of the host cell. The nucleus first divides and merozoites then form on the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vieira LS,Lima JD,Ribeiro MF,Bozzi IA,Camargos ER

更新日期：1997-07-01 00:00:00

abstract：:A sylvatic Triatoma infestans DM (dark morph) population detected in the Bolivian Chaco was characterized and compared with various domestic ones. The degree of differentiation of DM was clearly within the T. infestans intra-specific level. Nevertheless marked chromatic and morphometric differences as well as differen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Noireau F,Bastrenta B,Catalá S,Dujardin JP,Panzera F,Torres M,Perez R,Galvão C,Jurberg J

更新日期：2000-01-01 00:00:00

abstract：:The Americas are presently experiencing the most serious known outbreak of Zika virus (ZIKV). Here, we present a novel set of analyses using environmental characteristics, vector mosquito distributions, and socioeconomic risk factors to develop the first map to detail global ZIKV transmission risk in multiple dimensio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Samy AM,Thomas SM,Wahed AA,Cohoon KP,Peterson AT

更新日期：2016-09-01 00:00:00

abstract：:This study updates the geographic distributions of phlebotomine species in Central-West Brazil and analyses the climatic factors associated with their occurrence. The data were obtained from the entomology services of the state departments of health in Central-West Brazil, scientific collections and a literature revie...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Almeida PS,Andrade AJ,Sciamarelli A,Raizer J,Menegatti JA,Hermes SC,Carvalho Mdo S,Gurgel-Gonçalves R

更新日期：2015-06-01 00:00:00

abstract：:The schistosomal parasite plays a critical role in the development of malignant lesions in different organs. The pathogenesis of cancer is currently under intense investigation to identify reliable prognostic indices for disease detection. The objective of this paper is to evaluate certain biochemical parameters as di...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Hamed MA,Ahmed SA,Khaled HM

更新日期：2011-05-01 00:00:00

abstract：:Benznidazole (Bz) exhibits toxic side effects in animal studies and clinical use. Reductive metabolism of Bz in liver microsomes modulates the duration of its chemotherapeutic effect and its toxicity. The rate of this metabolism depends on age and is less intense in newborns and youngsters than in adults. In the prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bulffer RF,Castro JA,Fanelli SL

更新日期：2011-05-01 00:00:00