Bone marrow cell migration to the heart in a chimeric mouse model of acute chagasic disease.

abstract：:Acute infection with Trypanosoma cruzi results in intense myocarditis, which progresses to a chronic, asymptomatic indeterminate form. The evolution toward this chronic cardiac form occurs in approximately 30% of all cases of T. cruzi infection. Suppression of delayed type hypersensitivity (DTH) has been proposed as a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Thé TS,Portella RS,Guerreiro ML,Andrade SG

更新日期：2013-09-01 00:00:00

abstract：:From May to August 1999, we evaluated 401 patients from a pediatric hospital of Havana City. One group was composed of 113 patients with diarrhea admitted to the Gastroenterology ward and a second consisted of 288 patients without diarrhea, admitted for other reasons, and hospitalized within the same time period. Thre...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Núñez FA,González OM,González I,Escobedo AA,Cordoví RA

更新日期：2003-06-01 00:00:00

abstract：:In the Saimiri monkey, an experimental host for human malaria, acquired protection against Plasmodium falciparum blood stages depends on the IgG antibody populations developed. In vivo protective anti-falciparum activity of IgG antibodies is correlated with the in vitro opsonizing activity promoting phagocytosis of pa...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gysin J

更新日期：1992-01-01 00:00:00

abstract：:Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva JR,Medeiros LC,Reis VP,Chavez JH,Munhoz TD,Borges GP,Soares OA,Campos CH,Machado RZ,Baldani CD,Silva ML,Faria JL,Silva EE,Figueiredo LT

更新日期：2013-11-01 00:00:00

abstract：:Living in close association with a vertebrate host and feeding on its blood requires different types of adaptations, including behavioural adjustments. Triatomines exhibit particular traits associated with the exploitation of their habitat and food sources and these traits have been the subject of intense analysis. Ma...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lazzari CR,Lorenzo MG

更新日期：2009-07-01 00:00:00

abstract：:The alpha-glycerophosphate dehydrogenase (alpha-GPDH) activity in flight muscles of Panstrongylus megistus and Triatoma sordida, vectors of Chagas disease in Brazil, was studied. Both species showed higher enzymatic activities in fliers than in non-fliers insects. T. sordida exhibited a higher proportion of flier inse...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Soares RP,Santoro MM

更新日期：2000-09-01 00:00:00

abstract：:Angiostrongylus cantonensis is the etiologic agent of eosinophilic meningoencephalitis in humans. Cases have been recorded in many parts of the world, including Brazil. The aim of this study was to compare the differences in the biology and morphology of two different Brazilian haplotypes of A. cantonensis: ac8 and ac...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Monte TC,Gentile R,Garcia J,Mota E,Santos JN,Maldonado Júnior A

更新日期：2014-12-01 00:00:00

abstract：:Toxocara cati is a common feline parasite transmitted by the ingestion of embryonated eggs, by the transmammary route or by predation of paratenic hosts harbouring third-stage larvae in their bodies. In the present study, the larval distribution of T. cati in tissues and organs of Rattus norvegicus experimentally infe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos SV,Lescano SZ,Castro JM,Chieffi PP

更新日期：2009-09-01 00:00:00

abstract：:The triatomine bug Triatoma infestans probably originated in Bolivia and dispersed passively over wide areas of South America, where it is the principal vector of Trypanosoma cruzi. In the region of its probable origin this species shows colonization in two different ecotopes, so that it may be encountered in sylvatic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pires HH,Barbosa SE,Diotaiuti L

更新日期：2000-11-01 00:00:00

abstract：:Phlebotominae includes some vector species, mainly that of leishmaniases, with a very old host-parasite relationship. Some species fossils of this subfamily have been recently described and this paper presents the description of a new sand fly Pintomyia (Pifanomyia) paleotownsendi sp. nov in amber. The gonostyle prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Filho JD,Falcão AL,Galati EA,Brazil RP

更新日期：2006-12-05 00:00:00

abstract：:Goats from the Venezuelan northern arid zones were found infested by the following nematodes: Haemonchus contortus, Trichostrongylus axei, T. colubriformis, Cooperia curticei, Oesophagostomum columbianum, Skrjabinema ovis y Trichuris globulosa. The Shannon-Weaver index of diversity values oscillated between 0.045 and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morales G,Pino LA,Aldana E,Perdomo L,Molina E

更新日期：1986-04-01 00:00:00

abstract：:Heteroxenic and monoxenic trypanosomatids were screened for the presence of actin using a mouse polyclonal antibody produced against the entire sequence of the Trypanosoma cruzi actin gene, encoding a 41.9 kDa protein. Western blot analysis showed that this antibody reacted with a polypeptide of approximately 42 kDa i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza LC,Pinho RE,Lima CV,Fragoso SP,Soares MJ

更新日期：2013-08-01 00:00:00

abstract：:In many helminth infected hosts the number of eosinophils increases dramatically, often without any concurrent increases in the number of other leukocytes, so that eosinophils become the dominant cell type. Many experimental investigations have shown that the eosinophilia is induced by interleukin-5 (IL-5) but its fun...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ovington KS,Behm CA

更新日期：1997-01-01 00:00:00

abstract：:There is a paucity of studies on the cell biology of Sporothrix luriei, the less common of the pathogenic Sporothrix species worldwide. The production of DHN-melanin, eumelanin, and pyomelanin were evaluated on the mycelial and yeast forms of the S. luriei ATCC 18616 strain. The mycelial form of this species produced ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cruz ILR,Figueiredo-Carvalho MHG,Zancopé-Oliveira RM,Almeida-Paes R

更新日期：2018-01-01 00:00:00

abstract：:The insect fat body plays major roles in the intermediary metabolism, in the storage and transport of haemolymph compounds and in the innate immunity. Here, the overall structure of the fat body of five species of mosquitoes (Aedes albopictus, Aedes fluviatilis, Culex quinquefasciatus, Anopheles aquasalis and Anophele...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins GF,Serrão JE,Ramalho-Ortigão JM,Pimenta PF

更新日期：2011-09-01 00:00:00

abstract：:Type I diabetes mellitus (insulin-dependent DM = IDDM) is a chronic disease characterized by specific destruction of pancreatic beta cells, resulting in an absolute lack of insulin. Immune mechanisms, genetic susceptibility, and environmental factors are all implicated in the pathogenesis of Type 1 diabetes. This stud...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fidan I,Yüksel S,Kalkanci A,Imir T,Kustimur S

更新日期：2005-12-01 00:00:00

abstract：:In the present paper, we developed a primary culture of Rhodnius prolixus salivary gland and main salivary canal cells. Cells remained viable in culture for 30 days. Three types of cells were indentified in the salivary gland cultures, with binuclear cells being the most abundant. The supernatants of salivary cultures...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rocha FF,Araujo RN,Silva LM,Gontijo NF,Pereira MH

更新日期：2010-03-01 00:00:00

abstract：:Virulence and antibiotic resistance are significant determinants of the types of infections caused by Staphylococcus aureus and paediatric groups remain among the most commonly affected populations. The goal of this study was to characterise virulence genes of methicillin-susceptible S. aureus (MSSA) and methicillin-r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jiménez JN,Ocampo AM,Vanegas JM,Rodríguez EA,Garcés CG,Patiño LA,Ospina S,Correa MM

更新日期：2011-12-01 00:00:00

abstract：:The first steps in leishmaniasis are critical in determining the evolution of the disease. Major advances have recently been done in understanding this crucial moment. Fundamental research in parasite-vector interaction, parasite biology, insect saliva, and vertebrate host response have shed new light and uncovered a ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Almeida MC,Vilhena V,Barral A,Barral-Netto M

更新日期：2003-10-01 00:00:00

abstract：:Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum malaria that continues to be a major global health problem. Brain vascular dysfunction is a main factor underlying the pathogenesis of CM and can be a target for the development of adjuvant therapies for the disease. Vascular occlusion b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Carvalho LJ,Moreira Ada S,Daniel-Ribeiro CT,Martins YC

更新日期：2014-08-01 00:00:00

abstract：:The presence of tRNA array, a region with high tRNA gene number and density, has been demonstrated in Mycobacterium genus. However, a recent phylogenomic study revealed the existence of five distinct monophyletic groups (genera) within this genus. Considering this new scenario, and based on in-silico analyses, we have...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morgado SM,Vicente ACP

更新日期：2019-01-01 00:00:00

abstract：:Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice with IL-12 or anti-IL-2 or anti-IL-4 before i.v. injection of eggs increased IFN-gamma production and downregulated Th2 responses and pulmonary granuloma size. Conversely, anti-IFN-gamma antibody treatment increased Th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cheever AW,Jankovic D,Yap GS,Kullberg MC,Sher A,Wynn TA

更新日期：1998-01-01 00:00:00

abstract：:Analgesic and anti-inflammatory activities of water (WE) and ethanolic (EE) extracts of Scoparia dulcis L. were investigated in rats and mice, and compared to the effects induced by Glutinol, a triterpene isolated by purification of EE. Oral administration (p.o.) of either WE or EE (up to 2 g/kg) did not alter the nor...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Freire SM,Torres LM,Roque NF,Souccar C,Lapa AJ

更新日期：1991-01-01 00:00:00

abstract：:Details are given of the prevalence rates of onchocerciasis from the most recent surveys (1989) conducted in northern Ecuador. The disease has intensified and dispersed considerably due to migration of infected individuals and the presence of a highly efficient vector. Comparison of these data with those from two prev...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guderian RH,Shelley AJ

更新日期：1992-07-01 00:00:00

abstract：:Facilitated and improved by advances in molecular biology, techniques for the immunodiagnosis of schistosomiasis, including assays based on the detection of antigens circulating in the serum and/or excreted in the urine, have now reached the stage of multi-centre trials. There is a need to complement parasitological t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bergquist NR

更新日期：1992-01-01 00:00:00

abstract：:Trypanosomes are parasitic protozoa in which gene expression is primarily controlled through the regulation of mRNA stability and translation. This post-transcriptional control is mediated by various families of RNA-binding proteins, including those with zinc finger CCCH motifs. CCCH zinc finger proteins have been sho...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mörking PA,Rampazzo Rde C,Walrad P,Probst CM,Soares MJ,Gradia DF,Pavoni DP,Krieger MA,Matthews K,Goldenberg S,Fragoso SP,Dallagiovanna B

更新日期：2012-09-01 00:00:00

abstract：:Calomys callosus, Rengger 1830 (Rodentia, Cricetidae), a wild rodent found in Central Brazil, was studied to investigate its susceptibility to Toxoplasma gondii experimental infection and its humoral immune response against this protozoa. The electrophoretic profile of the serum proteins of C. callosus showed that IgG...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Favoreto-Júnior S,Ferro EA,Clemente D,Silva DA,Mineo JR

更新日期：1998-01-01 00:00:00

abstract：:In Brazil, until 2004, the immunization policy against diphtheria involved childhood vaccination with no official routine booster dose administered after 15 years of age. This study assessed functional antibody levels against diphtheria among blood donors. A total of 140 blood samples were collected, and diphtheria an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pimenta FP,Damasco PV,Cerbino Neto J,Lopes GS,Hirata R Jr,Milagres LG,Mattos-Guaraldi AL

更新日期：2006-06-01 00:00:00

abstract：:The global emergence and spread of malaria parasites resistant to antimalarial drugs is the major problem in malaria control. The genetic basis of the parasite's resistance to the antimalarial drug chloroquine (CQ) is well-documented, allowing for the analysis of field isolates of malaria parasites to address evolutio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sutar SK,Gupta B,Ranjit M,Kar SK,Das A

更新日期：2011-02-01 00:00:00

abstract：:Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abath FG,Xavier EM,Montenegro SM,Werkhauser RP

更新日期：2002-01-01 00:00:00