Abstract：
:Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) defines a subgroup of patients with asthma who have persistent airflow obstruction or patients with COPD who may exhibit variable airflow limitation and/or evidence of type 2 inflammation. Additional investigations are needed to determine whether ACO represents a distinct disorder with unique underlying pathophysiology, whether ACO patients should be managed differently from those with asthma or COPD, and whether the diagnosis affects long-term outcomes. This article presents the data about the clinical features of ACO, the current information regarding the underlying pathophysiology of the syndrome, and current understanding of therapeutic options.
journal_name
Immunol Allergy Clin North Amjournal_title
Immunology and allergy clinics of North Americaauthors
Sharma S,Khurana S,Federman AD,Wisnivesky J,Holguin Fdoi
10.1016/j.iac.2020.07.002subject
Has Abstractpub_date
2020-11-01 00:00:00pages
565-573issue
4eissn
0889-8561issn
1557-8607pii
S0889-8561(20)30046-1journal_volume
40pub_type
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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更新日期：2011-11-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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更新日期：2005-08-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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abstract：:The major treatment strategies for DH are gluten restriction or medical treatment with sulfones. Control of the cutaneous manifestations, but not the gastrointestinal changes, is rapid with dapsone. In addition to control of the cutaneous signs and symptoms of DH, dietary gluten restriction also induces improvement of...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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