Abstract：
:A new form of hereditary angioedema (HAE) was identified in the year 2000. Its clinical appearance resembles HAE types I and II, which are caused by mutations that result in a deficiency of C1 inhibitor (C1-INH). In patients with the new form of HAE, C1-INH plasma levels and function values are normal, so it's termed HAE with normal C1-INH (HAE-nC1). HAE-nC1, in a subgroup of patients, is thought to be caused by mutations that affect the F12 gene. The diagnosis of HAE-nC1 is based on history and clinical criteria. There are no licensed drugs with proven treatment effects for HAE-nC1.
journal_name
Immunol Allergy Clin North Amjournal_title
Immunology and allergy clinics of North Americaauthors
Magerl M,Germenis AE,Maas C,Maurer Mdoi
10.1016/j.iac.2017.04.004subject
Has Abstractpub_date
2017-08-01 00:00:00pages
571-584issue
3eissn
0889-8561issn
1557-8607pii
S0889-8561(17)30045-0journal_volume
37pub_type
杂志文章,评审abstract：:Evaluation of antibodies produced after immunization is central to immune deficiency diagnosis. This includes assessment of responses to routine immunizations as well as to vaccines administered specifically for diagnosis. Here, we present the basic concepts of the humoral immune response and their relevance for vacci...
journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2015.05.006
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2008.06.003
更新日期：2008-11-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2020.07.002
更新日期：2020-11-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2018.08.004
更新日期：2019-02-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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更新日期：2006-11-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2007.03.007
更新日期：2007-05-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章
doi：10.1016/j.iac.2009.10.004
更新日期：2010-02-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2008.10.006
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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abstract：:Chemical agents cause approximately 40% of cases of occupational asthma (OA). Diagnosis of OA caused by chemicals relies on the demonstration of decrements in lung function at the workplace or during a controlled specific inhalation challenge to the suspect chemical agent. Evaluation of workers is accomplished best wi...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0889-8561(02)00084-x
更新日期：2003-05-01 00:00:00
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章
doi：10.1016/j.iac.2011.02.011
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journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章
doi：10.1016/j.iac.2005.09.003
更新日期：2005-11-01 00:00:00
abstract：:Chronic rhinosinusitis (CRS) has a substantial impact on patients' quality of life (QOL). Among the many metrics available for measuring treatment success in CRS, patient-reported outcome measures that quantify changes in QOL are the most widely used methods. In addition, objective data from imaging, endoscopy, and ol...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
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abstract：:The psychologic and behavioral components of sickness represent, together with fever response and associated neuroendocrine changes, a highly organized strategy of the organism to fight infection. This strategy, referred to as sickness behavior, is triggered by the proinflammatory cytokines produced by activated cells...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章
doi：10.1016/j.iac.2009.02.002
更新日期：2009-05-01 00:00:00
abstract：:Moderate to severe atopic dermatitis (AD) negatively affects patients and their families. Pruritus, scratching, and sleep problems are common complaints linked to disturbed quality of life. Treatment is complex, and nonadherence rates are high. This article reviews the effect of AD on patients and their families and i...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章
doi：10.1016/j.iac.2010.05.003
更新日期：2010-08-01 00:00:00
abstract：:Food allergy is an emerging epidemic in the United States and the Western world. The determination of factors that make certain foods allergenic is still not clearly understood. Only a tiny fraction of thousands of proteins and other molecules is responsible for inducing food allergy. In this review, the authors prese...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2011.12.003
更新日期：2012-02-01 00:00:00
abstract：:Certain medications can generate asthma symptoms, with the potential to cause considerable morbidity. This article focuses on the common drugs that have the potential to cause distinct respiratory reactions in asthmatics: aspirin and other nonsteroidal anti-inflammatory drugs, beta-blockers, and angiotensin-converting...
journal_title：Immunology and allergy clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.iac.2004.09.009
更新日期：2005-02-01 00:00:00
