Abstract:
:Excessive dynamic airway collapse is a relatively new diagnosis separate from tracheobronchomalacia that is manifested by functional collapse of the large airways. Most commonly described in patients with underlying obstructive lung disease such as chronic obstructive pulmonary disease and asthma, it may contribute to increased dyspnea, cough, or exacerbations. There are few data published on the role of excessive dynamic airway collapse as related specifically to exercise. It was recently described as the cause for exertional dyspnea in individuals without underlying lung disease.
journal_name
Immunol Allergy Clin North Amjournal_title
Immunology and allergy clinics of North Americaauthors
Morris MJ,Woods JT,McLaughlin CWdoi
10.1016/j.iac.2018.01.006subject
Has Abstractpub_date
2018-05-01 00:00:00pages
325-332issue
2eissn
0889-8561issn
1557-8607pii
S0889-8561(18)30006-7journal_volume
38pub_type
杂志文章,评审abstract::This article reviews the dermatologic and allergic conditions of the eyelid. Topics include various eyelid dermatitis, inflammatory lesions, infections, benign and malignant tumor, urticaria, vascular lesions, and others. Treatment considerations for these conditions of the eyelid are also discussed. ...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2007.12.004
更新日期:2008-02-01 00:00:00
abstract::Allergic rhinitis affects a large portion of the population. Patients are frequently sensitized to indoor allergens. The most important contributors are house dust mites, pets, and fungi. In very controlled environments where allergen exposure is significantly reduced, individuals have been shown to have clinical impr...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章
doi:10.1016/j.iac.2011.05.005
更新日期:2011-08-01 00:00:00
abstract::Fractional concentration of exhaled nitric oxide (FENO) is a biomarker used to identify allergic airway inflammation. Because it is noninvasive and easy to obtain, its utility has been studied in the diagnosis and management of several respiratory diseases. Much of the research has been done in asthma, and many studie...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2018.06.001
更新日期:2018-11-01 00:00:00
abstract::In summary, the major physiologic changes that occur in pregnancy are the increased minute ventilation, which is caused by increased respiratory center sensitivity and drive; a compensated respiratory alkalosis; and a low expiratory reserve volume. The vital capacity and measures of forced expiration are well preserve...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2005.10.004
更新日期:2006-02-01 00:00:00
abstract::The first rule of environmental allergen control is that avoidance is appropriate for allergic patients with asthma. Although this rule is obvious to allergists, it frequently is not considered by families and physicians who are not trained in allergy. The next step in environmental avoidance is to determine the speci...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8561(03)00003-1
更新日期:2003-08-01 00:00:00
abstract::Atopic dermatitis (AD) is a heterogeneous disease and many attempts have been made to define subsets of patients based on clinical characteristics. However, the current characterization of patients with AD might not adequately reflect the pathophysiologic diversity within patients with AD. This article reviews current...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2016.08.008
更新日期:2017-02-01 00:00:00
abstract::The symptomatic hypereosinophilic patient must be approached in a stepwise manner, with thorough assessment to determine whether the hypereosinophilia itself is contributing to damage and disease manifestations (thereby defining a hypereosinophilic syndrome), and to identify an eventual cause of hypereosinophilia, fol...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2015.05.006
更新日期:2015-08-01 00:00:00
abstract::Inherited defects in components of the nonhomologous end-joining DNA repair mechanism produce a T-B-NK+ severe combined immunodeficiency disease (SCID) characterized by heightened sensitivity to ionizing radiation. Patients with the radiosensitive form of SCID may also have increased short- and long-term sensitivity t...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章
doi:10.1016/j.iac.2009.10.004
更新日期:2010-02-01 00:00:00
abstract::Atopic dermatitis (AD) is a common inflammatory condition of the skin that is usually seen in childhood, but can onset or persist into adulthood. The characteristic distribution and morphology based on age, chronic relapsing course, and pruritus comprise the clinical criteria used in the diagnosis of AD. However, the ...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2016.08.009
更新日期:2017-02-01 00:00:00
abstract::Eosinophilic gastrointestinal diseases (EGIDs) encompass a variety of disorders including eosinophilic esophagitis (EE), eosinophilic gastroenteritis (EG), and eosinophilic colitis. Although the pathogenesis of EGIDs is still poorly understood, dietary food antigens have been shown to cause EGIDs through several short...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2008.10.006
更新日期:2009-02-01 00:00:00
abstract::Recurrent infections in children are a cause for concern. It is essential to distinguish simple recurrent infections caused by exposures in the day care or school settings from those caused by inherent deficiencies in the immune system or other systemic diseases. Multiple diagnostic tools are available for the evaluat...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2015.07.005
更新日期:2015-11-01 00:00:00
abstract::Angioedema usually occurs within the setting of allergic diseases or urticaria, but situations occur in which angioedema itself represents a disease, such as in hereditary angioedema. Evaluation of patients for recurrent angioedema without wheals must take into account both specific clinical signs and symptoms and spe...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2013.07.001
更新日期:2013-11-01 00:00:00
abstract::In the 1970s and 1980s, scientific methods were introduced in the standardization of allergen vaccines and, in combination with improved documentation of the clinical benefits obtained using standardized vaccines, specific allergy treatment as a scientifically based, reproducible, and safe treatment for allergic disea...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2006.02.012
更新日期:2006-05-01 00:00:00
abstract::Exercise-induced anaphylaxis is an uncommon disorder in which anaphylaxis occurs in response to physical exertion. Food-dependent exercise-induced anaphylaxis is a disorder with similar symptoms, although symptoms develop only if exercise takes place within a few hours of eating and, in most cases, only if a specific ...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2015.01.005
更新日期:2015-05-01 00:00:00
abstract::Urticaria and angioedema are commonly encountered complaints in children. Although the diagnosis is clear, establishing an etiology, especially with respect to chronic urticaria, can be challenging. A significant proportion of chronic urticarial cases are now considered to have an autoimmune etiology. This article rev...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2005.03.003
更新日期:2005-05-01 00:00:00
abstract::Asthma exacerbations are a significant cause of health care use and mortality. Home management strategies may be effective in managing many exacerbations before presentation to a health care institution. This article focuses on the variety of options available to patients and providers to choose from as they customize...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2019.07.010
更新日期:2019-11-01 00:00:00
abstract::Stress reduction interventions can have a positive therapeutic effect in autoimmune disease patients. Physicians and patients must recognize the potential for stress to impact autoimmune diseases and how stress management should be considered in a multidimensional treatment approach. This article evaluates the effects...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2010.09.004
更新日期:2011-02-01 00:00:00
abstract::Aspirin-exacerbated respiratory disease is a significant endotype of both asthma and chronic rhinosinusitis with nasal polyps. The disease demonstrates what seems to be a unified inflammatory mechanism culminating in highly eosinophilic nasal polyp disease and asthma. The rate of polyp recurrence and morbidity from as...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2016.06.002
更新日期:2016-11-01 00:00:00
abstract::"Nonallergic rhinitis" (NAR) is defined by intermittent or persistent nasal symptoms without evidence of immunoglobulin E-mediated sensitization to relevant aeroallergens. The largest subgroup is idiopathic, and is characterized by nasal hyperreactivity to nonspecific environmental triggers, including temperature, hum...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2015.12.013
更新日期:2016-05-01 00:00:00
abstract::This article focuses on issues of safety and monitoring when immunosuppressive pharmacologic therapies are prescribed for the treatment of connective tissue disease (CTD)-associated interstitial pneumonias, vasculitides, and bronchiolitis. Prospective, randomized placebo-controlled clinical trials have yet to be perfo...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2012.07.001
更新日期:2012-11-01 00:00:00
abstract::Delayed pressure urticaria is a mechanical urticaria in which pressure causes whealing. Delayed cutaneous erythema and edema occur in association with marked subcutaneous swelling after the application of a sustained pressure stimulus to the skin. The earliest reports and theories of the pathogenesis of delayed pressu...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2004.01.006
更新日期:2004-05-01 00:00:00
abstract::Several biologics are currently FDA approved for asthma that target Th2 high patients. Unfortunately, 50% of patients with severe asthma do not fit this phenotype of disease and have fewer effective therapeutic options. In the clinical setting, total IgE, FeNO and peripheral blood eosinophils are important tools in de...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2017.01.007
更新日期:2017-05-01 00:00:00
abstract::Mastocytosis is a World Health Organization-defined clonal mast cell disorder characterized by significant clinicopathologic heterogeneity. Despite this diversity, a mutation of the KIT gene, most commonly D816V, is found in almost all cases and believed a driver lesion. Peripheral blood allele-specific oligonucleotid...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2018.04.005
更新日期:2018-08-01 00:00:00
abstract::The major treatment strategies for DH are gluten restriction or medical treatment with sulfones. Control of the cutaneous manifestations, but not the gastrointestinal changes, is rapid with dapsone. In addition to control of the cutaneous signs and symptoms of DH, dietary gluten restriction also induces improvement of...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2012.04.007
更新日期:2012-05-01 00:00:00
abstract::Asthma is a heterogeneous disease in which various cytokines orchestrate airway inflammation. Tumor necrosis alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the modulation of inflammation in various diseases, including asthma. Although TNF-alpha blocking strategies have been an effective th...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2004.06.010
更新日期:2004-11-01 00:00:00
abstract::Food allergy is an emerging epidemic in the United States and the Western world. The determination of factors that make certain foods allergenic is still not clearly understood. Only a tiny fraction of thousands of proteins and other molecules is responsible for inducing food allergy. In this review, the authors prese...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2011.12.003
更新日期:2012-02-01 00:00:00
abstract::Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2014.02.004
更新日期:2014-05-01 00:00:00
abstract::The interplay of geographic, geochemical, and meteorologic factors combines to define distinct floristic zones in North America. Latitude, elevation, Pacific or Atlantic Ocean influence, continental air mass influence, mountains, and hills are contributory geographic factors. Hardiness zones are defined by the nadir o...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0889-8561(03)00029-8
更新日期:2003-08-01 00:00:00
abstract::The autoinflammatory diseases encompass approximately 30 monogenic disorders in which inborn errors in the innate immune system lead to episodic systemic inflammation. Largely mediated by dysregulation of myeloid cells, interleukin (IL)-1β, type I interferon, and NF-κB, these disorders have rapidly expanded over the p...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2018.08.004
更新日期:2019-02-01 00:00:00
abstract::Mast cells produce symptoms by local and remote effects of mediator release and by their presence in increased numbers in normal tissue and bone marrow, where they damage and impair normal organ function. Moreover, mast cells are long-lived and heterogeneous in their response to secretagogues and to inhibitors of medi...
journal_title:Immunology and allergy clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.iac.2006.05.006
更新日期:2006-08-01 00:00:00