Delayed pressure urticaria.

abstract：:The major treatment strategies for DH are gluten restriction or medical treatment with sulfones. Control of the cutaneous manifestations, but not the gastrointestinal changes, is rapid with dapsone. In addition to control of the cutaneous signs and symptoms of DH, dietary gluten restriction also induces improvement of...

journal_title：Immunology and allergy clinics of North America

authors： Cardones AR,Hall RP 3rd

更新日期：2012-05-01 00:00:00

abstract：:Mycoplasma pneumoniae and Chlamydophila pneumoniae are atypical bacteria that are frequently found in patients with asthma. A definitive diagnosis of infection is often difficult to obtain because of limitations with sampling and detection. Numerous animal studies have outlined mechanisms by which these infections may...

journal_title：Immunology and allergy clinics of North America

authors： Metz G,Kraft M

更新日期：2010-11-01 00:00:00

abstract：:Physical urticarias are a unique subgroup of chronic urticaria in which urticarial responses can be reproducibly induced by different specific physical stimuli acting on the skin. These conditions include urticaria factitia/symptomatic dermographism, delayed pressure urticaria, cold contact urticaria, heat contact urt...

journal_title：Immunology and allergy clinics of North America

authors： Abajian M,Schoepke N,Altrichter S,Zuberbier T,Maurer M

更新日期：2014-02-01 00:00:00

abstract：:During the last 2 decades, the continued development and the large-scale production of polyclonal immune serum globulin (ISG) preparations with improved safety and tolerability profiles have allowed treatment to focus on quality of life and long-term freedom from the complications of primary immune deficiency disease,...

journal_title：Immunology and allergy clinics of North America

authors： Berger M

更新日期：2008-05-01 00:00:00

abstract：:Asthma is an inflammatory condition of both the small and large airways. Recently the small airways have gained attention as studies have shown significant inflammation in the small airways in all severities of asthma. This inflammation has correlated with peripheral airway resistance and as a result, noninvasive meth...

journal_title：Immunology and allergy clinics of North America

authors： Finkas LK,Martin R

更新日期：2016-08-01 00:00:00

abstract：:"Nonallergic rhinitis" (NAR) is defined by intermittent or persistent nasal symptoms without evidence of immunoglobulin E-mediated sensitization to relevant aeroallergens. The largest subgroup is idiopathic, and is characterized by nasal hyperreactivity to nonspecific environmental triggers, including temperature, hum...

journal_title：Immunology and allergy clinics of North America

authors： Shusterman D

更新日期：2016-05-01 00:00:00

abstract：:Allergic rhinitis affects a large portion of the population. Patients are frequently sensitized to indoor allergens. The most important contributors are house dust mites, pets, and fungi. In very controlled environments where allergen exposure is significantly reduced, individuals have been shown to have clinical impr...

journal_title：Immunology and allergy clinics of North America

authors： Bush RK

更新日期：2011-08-01 00:00:00

abstract：:Inherited defects in components of the nonhomologous end-joining DNA repair mechanism produce a T-B-NK+ severe combined immunodeficiency disease (SCID) characterized by heightened sensitivity to ionizing radiation. Patients with the radiosensitive form of SCID may also have increased short- and long-term sensitivity t...

journal_title：Immunology and allergy clinics of North America

authors： Dvorak CC,Cowan MJ

更新日期：2010-02-01 00:00:00

abstract：:Aspirin-exacerbated respiratory disease is a significant endotype of both asthma and chronic rhinosinusitis with nasal polyps. The disease demonstrates what seems to be a unified inflammatory mechanism culminating in highly eosinophilic nasal polyp disease and asthma. The rate of polyp recurrence and morbidity from as...

journal_title：Immunology and allergy clinics of North America

authors： Stevenson DD,White AA

更新日期：2016-11-01 00:00:00

abstract：:This article reviews the primary immunodeficiencies that result in hypogammaglobulinemia or predominantly antibody deficiency disorders. This group makes up the largest proportion of patients with primary immunodeficiency. Significant advances have been made in understanding the molecular basis and clinical characteri...

journal_title：Immunology and allergy clinics of North America

authors： Yong PF,Chee R,Grimbacher B

更新日期：2008-11-01 00:00:00

abstract：:Mastocytosis is a World Health Organization-defined clonal mast cell disorder characterized by significant clinicopathologic heterogeneity. Despite this diversity, a mutation of the KIT gene, most commonly D816V, is found in almost all cases and believed a driver lesion. Peripheral blood allele-specific oligonucleotid...

journal_title：Immunology and allergy clinics of North America

authors： Falchi L,Verstovsek S

更新日期：2018-08-01 00:00:00

abstract：:Biologic agents (BAs) are important therapeutic tools; their use has rapidly expanded and they are used in oncology, immunology, and inflammatory diseases. Their use may be limited, however, by adverse drug reactions. This article reviews the current literature on clinical presentation and pathogenic mechanisms of bot...

journal_title：Immunology and allergy clinics of North America

authors： Vultaggio A,Castells MC

更新日期：2014-08-01 00:00:00

abstract：:Aspirin-exacerbated respiratory disease is a clinical syndrome characterized by severe, persistent asthma, hyperplastic eosinophilic sinusitis with nasal polyps, and reactions to aspirin and other nonsteroidal antiinflammatory drugs that preferentially inhibit cyclooxygenase 1. The mechanisms behind the therapeutic ef...

journal_title：Immunology and allergy clinics of North America

authors： Burnett T,Katial R,Alam R

更新日期：2013-05-01 00:00:00

abstract：:Heterogeneous presentations of disease pose particular diagnostic and management challenges to the clinician. Progestogen hypersensitivity (PH) classically consists of hypersensitivity symptoms to endogenous progesterone during the luteal phase of the menstrual cycle. However, with the rise of assisted fertility and t...

journal_title：Immunology and allergy clinics of North America

authors： Foer D,Buchheit KM

更新日期：2017-11-01 00:00:00

abstract：:Moderate to severe atopic dermatitis (AD) negatively affects patients and their families. Pruritus, scratching, and sleep problems are common complaints linked to disturbed quality of life. Treatment is complex, and nonadherence rates are high. This article reviews the effect of AD on patients and their families and i...

journal_title：Immunology and allergy clinics of North America

authors： Kelsay K,Klinnert M,Bender B

更新日期：2010-08-01 00:00:00

abstract：:The symptomatic hypereosinophilic patient must be approached in a stepwise manner, with thorough assessment to determine whether the hypereosinophilia itself is contributing to damage and disease manifestations (thereby defining a hypereosinophilic syndrome), and to identify an eventual cause of hypereosinophilia, fol...

journal_title：Immunology and allergy clinics of North America

authors： Roufosse F

更新日期：2015-08-01 00:00:00

abstract：:Angioedema usually occurs within the setting of allergic diseases or urticaria, but situations occur in which angioedema itself represents a disease, such as in hereditary angioedema. Evaluation of patients for recurrent angioedema without wheals must take into account both specific clinical signs and symptoms and spe...

journal_title：Immunology and allergy clinics of North America

authors： Cicardi M,Zanichelli A

更新日期：2013-11-01 00:00:00

abstract：:Since the initial reports of penicillin and beta-lactam drugs causing allergic reactions, much has been elucidated regarding their pathophysiology and mechanism of action. Despite advances in testing for penicillin allergy, with IgE antibodies and skin tests available for the major and minor determinants of penicillin...

journal_title：Immunology and allergy clinics of North America

authors： Thethi AK,Van Dellen RG

更新日期：2004-08-01 00:00:00

abstract：:Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) defines a subgroup of patients with asthma who have persistent airflow obstruction or patients with COPD who may exhibit variable airflow limitation and/or evidence of type 2 inflammation. Additional investigations are needed to determine whether ACO re...

journal_title：Immunology and allergy clinics of North America

authors： Sharma S,Khurana S,Federman AD,Wisnivesky J,Holguin F

更新日期：2020-11-01 00:00:00

abstract：:This article describes the efficacy, immunogenicity, and safety of CAIV-T. This vaccine has the potential to significantly contribute to the control of influenza infection and influenza-associated illnesses, including febrile otitis media and lower respiratory disease. When compared with inactivated vaccine, CAIV-T ha...

journal_title：Immunology and allergy clinics of North America

authors： Belshe RB,Mendelman PM

更新日期：2003-11-01 00:00:00

abstract：:This article summarizes the guidelines for using replacement therapy in the management of patients who have primary antibody deficiency. ...

journal_title：Immunology and allergy clinics of North America

authors： Roifman CM,Berger M,Notarangelo LD

更新日期：2008-11-01 00:00:00

abstract：:Asthma is a heterogeneous disease in which various cytokines orchestrate airway inflammation. Tumor necrosis alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the modulation of inflammation in various diseases, including asthma. Although TNF-alpha blocking strategies have been an effective th...

journal_title：Immunology and allergy clinics of North America

authors： Babu KS,Davies DE,Holgate ST

更新日期：2004-11-01 00:00:00

abstract：:In the last decade, gene therapy for adenosine deaminase deficiency has been developed as a successful alternative strategy to allogeneic bone marrow transplant and enzyme replacement therapy. Infusion of autologous hematopoietic stem cells, corrected ex vivo by retroviral vectors and combined to low-intensity conditi...

journal_title：Immunology and allergy clinics of North America

authors： Cappelli B,Aiuti A

更新日期：2010-05-01 00:00:00

abstract：:Hymenoptera venom allergy is a typical IgE-mediated reaction caused by sensitization to 1 or more allergens of the venom, and accounts for 1.5% to 34% of all cases of anaphylaxis. Patients suffering from mastocytosis are more susceptible to the anaphylactic reactions to an insect sting. This article aims to answer the...

journal_title：Immunology and allergy clinics of North America

authors： Niedoszytko M,Bonadonna P,Oude Elberink JN,Golden DB

更新日期：2014-05-01 00:00:00

abstract：:Thus far, the most effective strategy for the prevention of food allergy is early introduction of allergenic solids to at-risk infants. Early skin moisturization may have a role in food allergy prevention. There is insufficient evidence for hydrolyzed formula as a means of allergy prevention. Studies on vitamin D, ome...

journal_title：Immunology and allergy clinics of North America

authors： Abrams EM,Chan ES

更新日期：2019-11-01 00:00:00

abstract：:The autoinflammatory diseases encompass approximately 30 monogenic disorders in which inborn errors in the innate immune system lead to episodic systemic inflammation. Largely mediated by dysregulation of myeloid cells, interleukin (IL)-1β, type I interferon, and NF-κB, these disorders have rapidly expanded over the p...

journal_title：Immunology and allergy clinics of North America

authors： Broderick L

更新日期：2019-02-01 00:00:00

abstract：:Respiratory symptoms and asthma control questionnaires are poor predictors of the presence or severity of exercise-induced bronchoconstriction (EIB), and objective measurement is recommended. To optimize the chance of a positive test result, there are several factors to consider when exercising patients for EIB, inclu...

journal_title：Immunology and allergy clinics of North America

authors： Anderson SD,Kippelen P

更新日期：2013-08-01 00:00:00

abstract：:Respiratory viruses and allergens synergistically contribute to disease pathogenesis in asthma. Potential mechanisms underlying this clinically relevant association are the subject of intense investigation. This review summarizes current knowledge and recent advances in this area, with an emphasis on potential mechani...

journal_title：Immunology and allergy clinics of North America

authors： Rowe RK,Gill MA

更新日期：2015-02-01 00:00:00

abstract：:The first rule of environmental allergen control is that avoidance is appropriate for allergic patients with asthma. Although this rule is obvious to allergists, it frequently is not considered by families and physicians who are not trained in allergy. The next step in environmental avoidance is to determine the speci...

journal_title：Immunology and allergy clinics of North America

authors： Eggleston PA

更新日期：2003-08-01 00:00:00

abstract：:Food allergy is an emerging epidemic in the United States and the Western world. The determination of factors that make certain foods allergenic is still not clearly understood. Only a tiny fraction of thousands of proteins and other molecules is responsible for inducing food allergy. In this review, the authors prese...

journal_title：Immunology and allergy clinics of North America

authors： Masilamani M,Commins S,Shreffler W

更新日期：2012-02-01 00:00:00