Abstract:
:17,244 pathogens isolated from clinical specimens of 24 hospitals in the Moers area (North-Rhine Westphalia, FRG) were tested in regard to their susceptibility to Augmentin (amoxicillin and clavulanic acid). For this purpose, minimal inhibitory concentrations were determined by use of microbroth dilution technique. 80% of Gram-negative, 98% of Gram-positive and 97% of anaerobic isolates were susceptible to Augmentin (breakpoint 4 mg/l amoxicillin in the presence of 2.5 mg/l clavulanic acid). In a second part of the study the susceptibility to Augmentin of 4.137 Gram-negative and 10.958 Gram-positive pathogens was compared to their sensitivity against benzylpenicillin, flucloxacillin, mezlocillin, erythromycin, clindamycin, fusidic acid, ampicillin, cefaclor and doxycyclin.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Focht J,Klietmann W,Nösner K,Rolinson GN,Johnsen Jdoi
10.1159/000238588subject
Has Abstractpub_date
1988-01-01 00:00:00pages
332-40issue
4eissn
0009-3157issn
1421-9794journal_volume
34pub_type
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