Abstract:
:The aim of this research was to collect precise data on the antibacterial activity of ceftriaxone and cefotaxime in the respiratory tract. The diffusion into pulmonary tissue and bronchial secretion and the antibacterial activity of the two antibiotics were evaluated in vivo by means of the inhibitory quotient. Ceftriaxone administered at a dosage of 1 g (i.m.) every 24 h resulted in antibacterial levels against the sensitive pathogens over a period of 24 h after each dose. The antibacterial protection afforded by cefotaxime, given at the dosage of 1 g (i.m.) every 12 h, was not as marked and did not extend over the interval between two administrations.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Fraschini F,Scaglione Fdoi
10.1159/000238651subject
Has Abstractpub_date
1989-01-01 00:00:00pages
77-82issue
2eissn
0009-3157issn
1421-9794journal_volume
35pub_type
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