A pitfall associated with lactate detection using stimulated-echo proton spectroscopy.

Abstract:

:At TE values of 136 ms, it has recently been shown that the lactate methyl signal, when obtained with a stimulated-echo (STE) sequence, is modulated at the zero-quantum (ZQ) frequency when TM is varied. Here we describe an additional modulation of the ZQ lactate signal, due to spin-spin coupling, that results in a 10-fold reduction in the lactate signal for TM intervals ranging between 48 and 84 ms (and at multiples of 136 ms thereof). Because of this J-modulation, improper choice of TE and TM intervals may give false negative results for lactate detection by STE spectroscopy.

journal_name

Magn Reson Med

authors

Sotak CH,Alger JR

doi

10.1002/mrm.1910170223

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

533-8

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

17

pub_type

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