Abstract:
:A 3D sequence for dynamic susceptibility imaging is proposed which combines echo-shifting principles (such as PRESTO), sensitivity encoding (SENSE), and partial-Fourier acquisition. The method uses a moderate SENSE factor of 2 and takes advantage of an alternating partial k-space acquisition in the "slow" phase encode direction allowing an iterative reconstruction using high-resolution phase estimates. Offering an isotropic spatial resolution of 4 x 4 x 4 mm(3), the novel sequence covers the whole brain including parts of the cerebellum in 0.5 sec. Its temporal signal stability is comparable to that of a full-Fourier, full-FOV EPI sequence having the same dynamic scan time but much less brain coverage. Initial functional MRI experiments showed consistent activation in the motor cortex with an average signal change slightly less than that of EPI.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Klarhöfer M,Dilharreguy B,van Gelderen P,Moonen CTdoi
10.1002/mrm.10599subject
Has Abstractpub_date
2003-10-01 00:00:00pages
830-8issue
4eissn
0740-3194issn
1522-2594journal_volume
50pub_type
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