Is the detection of fucose cancer markers by 2D 1H NMR unequivocal?

Abstract:

:Fucose is believed to be a marker for cancer that may be detectable by the 2D proton NMR (COSY) of human plasma. However, the COSY technique is time consuming and prone to error. These problems may be alleviated by using the SUPERCOSY pulse sequence; this technique shows that there are many other cross peaks in the region (1.3, 4.2 ppm) which are not readily distinguishable from fucose.

journal_name

Magn Reson Med

authors

Phillips PS,Herring FG

doi

10.1002/mrm.1910150102

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

1-7

issue

1

eissn

0740-3194

issn

1522-2594

journal_volume

15

pub_type

杂志文章
  • Exploring the limits of RF shimming for high-field MRI of the human head.

    abstract::Several methods have been proposed for overcoming the effects of radiofrequency (RF) magnetic field inhomogeneity in high-field MRI. Some of these methods rely at least in part on the ability to independently control magnitude and phase of different drives in either one multielement RF coil or in different RF coils in...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21013

    authors: Mao W,Smith MB,Collins CM

    更新日期:2006-10-01 00:00:00

  • High-order coils as transmitters for NMR imaging.

    abstract::High-order radiofrequency transmitter coils are described that permit, in the context of NMR imaging, a knowledgeable trade-off between coil complexity and the degree of inhomogeneity over a specified volume of space. A mathematical formulation of high-order coils is developed for an axially symmetric polarizing dc fi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910030108

    authors: Sotgiu A,Hyde JS

    更新日期:1986-02-01 00:00:00

  • Fast maximum intensity projection algorithm using shear warp factorization and reduced resampling.

    abstract::Maximal intensity projection (MIP) is routinely used to view MRA and other volumetric angiographic data. The straightforward implementation of MIP is ray casting that traces a volumetric data set in a computationally expensive manner. This article reports a fast MIP algorithm using shear warp factorization and reduced...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10114

    authors: Fang L,Wang Y,Qiu B,Qian Y

    更新日期:2002-04-01 00:00:00

  • Impact of signal-to-noise on functional MRI.

    abstract::Functional magnetic resonance imaging (fMRI) has recently been adopted as an investigational tool in the field of neuroscience. The signal changes induced by brain activations are small ( approximately 1-2%) at 1.5T. Therefore, the signal-to-noise ratio (SNR) of the time series used to calculate the functional maps is...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/1522-2594(200012)44:6<925::aid-mrm14>3.0.c

    authors: Parrish TB,Gitelman DR,LaBar KS,Mesulam MM

    更新日期:2000-12-01 00:00:00

  • Assessing transneuronal dysfunction utilizing manganese-enhanced MRI (MEMRI).

    abstract::In this study we utilized manganese-enhanced MRI (MEMRI) to evaluate the in vivo transneuronal efficiency of manganese ion (Mn(2+)) movement as a means to assess overall changes in neuronal function. We designated this extension the manganese transfer index (MTI) value. To evaluate the MTI value as an index of transne...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21648

    authors: Serrano F,Deshazer M,Smith KD,Ananta JS,Wilson LJ,Pautler RG

    更新日期:2008-07-01 00:00:00

  • The flip-angle effect: a method for detection of sodium-23 quadrupole splitting in tissue.

    abstract::A method is presented for the detection of quadrupole splitting in tissue, where the spectral line splittings are typically unobservable. The method used is a study of the rate of rotation of the flip angle as a function of radiofrequency (rf) amplitude. Our results with samples of skeletal muscle and cat brain indica...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910040108

    authors: Joseph PM,Summers RM

    更新日期:1987-01-01 00:00:00

  • Diffusion/perfusion MR imaging of acute cerebral ischemia.

    abstract::In vivo echo-planar MR imaging was used to measure apparent diffusion coefficients (ADC) of cerebral tissues in a comprehensive noninvasive evaluation of early ischemic brain damage induced by occlusion of the middle cerebral artery (MCA) in a cat model of acute regional stroke. Within 10 min after arterial occlusion,...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910190220

    authors: Kucharczyk J,Mintorovitch J,Asgari HS,Moseley M

    更新日期:1991-06-01 00:00:00

  • Ultrashort TE T1rho (UTE T1rho) imaging of the Achilles tendon and meniscus.

    abstract::In this study, we report the use of a novel ultrashort echo time T(1)rhoT(1) sequence that combines a spin-lock preparation pulse with a two-dimensional ultrashort echo time sequence of a nominal echo time 8 microsec. The ultrashort echo time-T(1)rho sequence was employed to quantify T(1)rho in short T(2) tissues incl...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22474

    authors: Du J,Carl M,Diaz E,Takahashi A,Han E,Szeverenyi NM,Chung CB,Bydder GM

    更新日期:2010-09-01 00:00:00

  • Ultrahigh-resolution quantitative spinal cord MRI at 9.4T.

    abstract:PURPOSE:To present the results of the first human spinal cord in vivo MRI scans at 9.4T. METHODS:A human brain coil was used to image the human spinal cord at 9.4T. All anatomical images were acquired with a T2 *-weighted gradient-echo sequence. A comparison of the influence of four different B0 shimming routines on t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28455

    authors: Geldschläger O,Bosch D,Avdievich NI,Henning A

    更新日期:2021-02-01 00:00:00

  • Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.

    abstract::Magnetization transfer imaging (MT) and localized proton spectroscopy (1H-MRS) were utilized in the evaluation of lesions (high signal abnormalities on T2-weighted images) and normal-appearing white matter (NAWM) in multiple sclerosis (MS). Eleven patients with a clinical diagnosis of MS were independently evaluated w...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910320303

    authors: Hiehle JF Jr,Lenkinski RE,Grossman RI,Dousset V,Ramer KN,Schnall MD,Cohen JA,Gonzalez-Scarano F

    更新日期:1994-09-01 00:00:00

  • Comparison of k-space sampling schemes for multidimensional MR spectroscopic imaging.

    abstract::For clinical 31P MR spectroscopic imaging (MRSI) studies, where signal averaging is necessary, some improvement of sensitivity and spatial response function may be achieved by acquiring data over a spherical k-space volume and varying the number of averages acquired in proportion to the desired spatial filter. Eight d...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910360321

    authors: Hugg JW,Maudsley AA,Weiner MW,Matson GB

    更新日期:1996-09-01 00:00:00

  • Apparent changes of appearance of inversion-recovery images.

    abstract::This note considers the anomolous contrast in inversion recovery images produced by NMR scanners if a map of [My] is reconstructed, rather than a map of My'. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910020110

    authors: Young IR,Bailes DR,Bydder GM

    更新日期:1985-02-01 00:00:00

  • In vivo measurement of volumetric strain in the human brain induced by arterial pulsation and harmonic waves.

    abstract::Motion-sensitive phase contrast magnetic resonance imaging and magnetic resonance elastography are applied for the measurement of volumetric strain and tissue compressibility in human brain. Volumetric strain calculated by the divergence operator using a biphasic effective-medium model is related to dilatation and com...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24499

    authors: Hirsch S,Klatt D,Freimann F,Scheel M,Braun J,Sack I

    更新日期:2013-09-01 00:00:00

  • Fast Fourier imaging.

    abstract::A new NMR imaging technique, aiming at a reduction of the data acquisition time, is described in detail. The method is applicable in all multidimensional imaging situations where at least one spatial coordinate is resolved. Discussed at some length are the point-spread function, the required bandwidth of the NMR spect...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910020304

    authors: van Uijen CM,den Boef JH,Verschuren FJ

    更新日期:1985-06-01 00:00:00

  • Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast.

    abstract::In vivo effective relaxation rates in normal rat liver were evaluated for four dextran coated iron oxide agents: monocrystalline iron oxide nanocolloid (MION) with a mean particle diameter of 3.9 nm, a polycrystalline agent (PION) with a larger mean diameter of 12 nm, and these two agents labeled with the asialofetuin...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910370613

    authors: Mandeville JB,Moore J,Chesler DA,Garrido L,Weissleder R,Weisskoff RM

    更新日期:1997-06-01 00:00:00

  • SSFP signal with finite RF pulses.

    abstract::The theoretical description of steady state free precession (SSFP) sequences is generally well accepted and unquestioned, although it is based on instantaneously acting radiofrequency (RF) pulses. In practice, however, all excitation processes are finite, thereby questioning the overall validity of the common SSFP sig...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22116

    authors: Bieri O,Scheffler K

    更新日期:2009-11-01 00:00:00

  • T2 measurement in articular cartilage: impact of the fitting method on accuracy and precision at low SNR.

    abstract::T2 relaxation time is a promising MRI parameter for the detection of cartilage degeneration in osteoarthritis. However, the accuracy and precision of the measured T2 may be substantially impaired by the low signal-to-noise ratio of images available from clinical examinations. The purpose of this work was to assess the...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22178

    authors: Raya JG,Dietrich O,Horng A,Weber J,Reiser MF,Glaser C

    更新日期:2010-01-01 00:00:00

  • Bulk volume susceptibility difference between deoxyhemoglobin and oxyhemoglobin for HbA and HbS: A comparative study.

    abstract:PURPOSE:Sickle cell anemia is a blood disorder that alters the morphology and the oxygen affinity of the red blood cells. Cerebral oxygen extraction fraction measurements using quantitative BOLD contrast have been used for assessing inadequate oxygen delivery and the subsequent risk of ischemic stroke in sickle cell an...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28668

    authors: Eldeniz C,Binkley MM,Fields M,Guilliams K,Ragan DK,Chen Y,Lee JM,Ford AL,An H

    更新日期:2021-01-21 00:00:00

  • More accurate estimation of diffusion tensor parameters using diffusion Kurtosis imaging.

    abstract::With diffusion tensor imaging, the diffusion of water molecules through brain structures is quantified by parameters, which are estimated assuming monoexponential diffusion-weighted signal attenuation. The estimated diffusion parameters, however, depend on the diffusion weighting strength, the b-value, which hampers t...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22603

    authors: Veraart J,Poot DH,Van Hecke W,Blockx I,Van der Linden A,Verhoye M,Sijbers J

    更新日期:2011-01-01 00:00:00

  • Model of the human vasculature for studying the influence of contrast injection speed on cerebral perfusion MRI.

    abstract::Simulations of dynamic susceptibility contrast (DSC) MRI are frequently performed by assuming a certain shape for the input function and the microvascular response function. However, to investigate the influence of parameters that will affect the shape of the input function, a more complex model of the human vasculatu...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10567

    authors: van Osch MJ,Vonken EJ,Wu O,Viergever MA,van der Grond J,Bakker CJ

    更新日期:2003-09-01 00:00:00

  • Anisotropy of NMR properties of tissues.

    abstract::Orientational anisotropy of T2 and T1 relaxation times, diffusion, and magnetization transfer has been investigated for six different tissues: tendon, cartilage, kidney, muscle, white matter, and optic nerve. Relaxation anisotropy was observed for tendon and cartilage, and diffusional anisotropy was measured in kidney...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910320508

    authors: Henkelman RM,Stanisz GJ,Kim JK,Bronskill MJ

    更新日期:1994-11-01 00:00:00

  • Development and validation of 3D MP-SSFP to enable MRI in inhomogeneous magnetic fields.

    abstract:PURPOSE:We demonstrate the feasibility of MRI with missing-pulse steady-state free precession (MP-SSFP) in a 4T magnet with artificially degraded homogeneity. METHODS:T1 , T2 , and diffusion contrast of MP-SSFP was simulated with constant and alternate radiofrequency (RF) phase using an extended phase graph. To valida...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28469

    authors: Kobayashi N,Parkinson B,Idiyatullin D,Adriany G,Theilenberg S,Juchem C,Garwood M

    更新日期:2021-02-01 00:00:00

  • Piezoelectric-controlled tuning capacitor for surface coils.

    abstract::The design of a piezoelectric-controlled trimmer capacitor and its use as a tuning element of an MRI surface coil at 63.8 MHz are described. It is found that image quality does not depend strongly on match of the coil to the transmission line but that tuning can be a significant factor. The work is intended to lead ev...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910120106

    authors: Hyde JS,Rilling RJ,Jesmanowicz A,Kneeland JB

    更新日期:1989-10-01 00:00:00

  • Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge.

    abstract::Free induction decay signals are analyzed by fitting a model function directly in the time domain. No starting values are needed for linear model parameters, and omission of corrupted data points poses no problems. A significant gain of accuracy is achieved by imposing prior knowledge about the model parameters. ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910060111

    authors: van der Veen JW,de Beer R,Luyten PR,van Ormondt D

    更新日期:1988-01-01 00:00:00

  • Inversion recovery radial MRI with interleaved projection sets.

    abstract::The radial trajectory has found applications in cardiac imaging because of its resilience to undersampling and motion artifacts. Recent work has shown that interleaved and weighted radial imaging can produce images with multiple contrasts from a single data set. This feature was investigated for inversion recovery ima...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20865

    authors: Peters DC,Botnar RM,Kissinger KV,Yeon SB,Appelbaum EA,Manning WJ

    更新日期:2006-05-01 00:00:00

  • Characterization of aortic root atherosclerosis in ApoE knockout mice: high-resolution in vivo and ex vivo MRM with histological correlation.

    abstract::In vivo, cardiac-gated, black-blood, and ex vivo magnetic resonance microscopy (MRM) images of the aortic root, and histopathology data were obtained from 12 transgenic and wild-type (WT) mice. MRM was performed using a black-blood imaging spin-echo sequence with upstream and downstream in-flow saturation pulses to ob...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10360

    authors: Itskovich VV,Choudhury RP,Aguinaldo JG,Fallon JT,Omerhodzic S,Fisher EA,Fayad ZA

    更新日期:2003-02-01 00:00:00

  • Effects of the acoustic noise of the gradient systems on fMRI: a study on auditory, motor, and visual cortices.

    abstract::MR acoustic, or sound, noise due to gradient pulsing has been one of the problems in MRI, both in patient scanning as well as in many areas of psychiatric and neuroscience research, such as brain fMRI. Especially in brain fMRI, sound noise is one of the serious noise sources that obscures the small signals obtainable ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910390224

    authors: Cho ZH,Chung SC,Lim DW,Wong EK

    更新日期:1998-02-01 00:00:00

  • Reducing gradient imperfections for spiral magnetic resonance spectroscopic imaging.

    abstract::Spiral k-space magnetic resonance spectroscopic imaging (MRSI) requires high performance from gradient hardware systems. During the readout phase, oscillating gradients are continuously played out, which can cause undesired effects. These effects on the quality of SI data are non-intuitive because of their time-varyin...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20928

    authors: Kim DH,Spielman DM

    更新日期:2006-07-01 00:00:00

  • A new susceptibility-weighted image reconstruction method for the reduction of background phase artifacts.

    abstract:PURPOSE:To significantly reduce the background phase effects, especially at the air-tissue interface, and to enhance the desirable local structures of veins in susceptibility-weighted imaging. METHODS:In the proposed reconstruction method called Magnitude of Complex Filtering, a complex-valued magnetic resonance image...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24776

    authors: Lee Y,Han Y,Park H

    更新日期:2014-03-01 00:00:00

  • In vivo imaging of insulin-secreting human pancreatic ductal cells using MRI reporter gene technique: A feasibility study.

    abstract:PURPOSE:The purpose of this study was to investigate the feasibility of in vivo imaging of human pancreatic ductal cells by OATP1B3 reporter gene under MRI. METHODS:A human cell line (PANC-1) derived from the pancreatic ductal epithelium was used in this study. After transduction of OATP1B3, the cellular physiological...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27749

    authors: Wu MR,Hsiao JK,Liu HM,Huang YY,Tseng YJ,Chou PT,Weng TI,Yang CY

    更新日期:2019-08-01 00:00:00