Abstract:
PURPOSE:Molecular imaging is the visualization and identification of specific molecules in anatomy for insight into metabolic pathways, tissue consistency, and tracing of solute transport mechanisms. This paper presents the Molecular Imaging Data Grid (MIDG) which utilizes emerging grid technologies in preclinical molecular imaging to facilitate data sharing and discovery between preclinical molecular imaging facilities and their collaborating investigator institutions to expedite translational sciences research. Grid-enabled archiving, management, and distribution of animal-model imaging datasets help preclinical investigators to monitor, access and share their imaging data remotely, and promote preclinical imaging facilities to share published imaging datasets as resources for new investigators. METHODS:The system architecture of the Molecular Imaging Data Grid is described in a four layer diagram. A data model for preclinical molecular imaging datasets is also presented based on imaging modalities currently used in a molecular imaging center. The MIDG system components and connectivity are presented. And finally, the workflow steps for grid-based archiving, management, and retrieval of preclincial molecular imaging data are described. RESULTS:Initial performance tests of the Molecular Imaging Data Grid system have been conducted at the USC IPILab using dedicated VMware servers. System connectivity, evaluated datasets, and preliminary results are presented. The results show the system's feasibility, limitations, direction of future research. CONCLUSIONS:Translational and interdisciplinary research in medicine is increasingly interested in cellular and molecular biology activity at the preclinical levels, utilizing molecular imaging methods on animal models. The task of integrated archiving, management, and distribution of these preclinical molecular imaging datasets at preclinical molecular imaging facilities is challenging due to disparate imaging systems and multiple off-site investigators. A Molecular Imaging Data Grid design, implementation, and initial evaluation is presented to demonstrate the secure and novel data grid solution for sharing preclinical molecular imaging data across the wide-area-network (WAN).
journal_name
Int J Comput Assist Radiol Surgauthors
Lee J,Documet J,Liu B,Park R,Tank A,Huang HKdoi
10.1007/s11548-010-0524-6subject
Has Abstractpub_date
2011-03-01 00:00:00pages
285-96issue
2eissn
1861-6410issn
1861-6429journal_volume
6pub_type
杂志文章abstract:PURPOSE:Most ultrasound imaging systems assume a pre-determined sound propagation speed for imaging. However, a mismatch between assumed and real sound speeds can lead to spatial shift and defocus of ultrasound image, which may limit the applicability of ultrasound imaging. The estimation of real sound speed is importa...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-012-0690-9
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To develop an image analysis method that can automatically find correlations between a set of plain radiographs and continuous clinical or physiological indicators. METHODS:Knee X-rays taken from the Baltimore Longitudinal Study of Aging are used in this study. The computer analysis method is based on the WND-...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-011-0550-z
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Effectiveness of image-guided radiation therapy with precise dose delivery depends highly on accurate target localization, which may involve motion during treatment due to, e.g., breathing and drift. Therefore, it is important to track the motion and adjust the radiation delivery accordingly. Tracking generally...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-017-1559-8
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:The most commonly used imaging device for assessment of fracture reduction is the two-dimensional X-ray fluoroscope. Two recently introduced 3D fluoroscopic devices, the Siremobil ISO-C3D (Siemens) and the C-InSight (Mazor Surgical Technologies), enable the surgeon to obtain spatial information for the assess...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-011-0548-6
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:This paper presents a novel 3D multimodal registration strategy to fuse 3D real-time echocardiography images with cardiac cine MRI images. This alignment is performed in a saliency space, which is designed to maximize similarity between the two imaging modalities. This fusion improves the quality of the availab...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-019-02087-w
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) tends to show higher diagnostic accuracy than other modalities. There is a demand for computer-assisted detection (CAD) software for Gd-EOB-DTPA-enhanced MRI. Segmentation with high accuracy is im...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-019-01935-z
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Sustained delivery of regenerative retinal therapies by robotic systems requires intra-operative tracking of the retinal fundus. We propose a supervised deep convolutional neural network to densely predict semantic segmentation and optical flow of the retina as mutually supportive tasks, implicitly inpainting r...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-020-02160-9
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Patient-specific quantitative assessments of muscle mass and biomechanical musculoskeletal simulations require segmentation of the muscles from medical images. The objective of this work is to automate muscle segmentation from CT data of the hip and thigh. METHOD:We propose a hierarchical multi-atlas method in...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-018-1758-y
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:Fusion of pre/perioperative images and intra-operative images may add relevant information during image-guided procedures. In abdominal procedures, respiratory motion changes the position of organs, and thus accurate image guidance requires a continuous update of the spatial alignment of the (pre/perioperative)...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-015-1218-x
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Oral disorders such as temporomandibular joint disorders (TMD) and dry mouth are common and often require treatment. Maxillofacial massage is used as a complementary and alternative therapy for these disorders. We developed an oral rehabilitation robot that massages the maxillofacial tissues for this purpose. I...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-009-0383-1
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:Airway tree segmentation plays a pivotal role in chest computed tomography (CT) analysis tasks such as lesion localization, surgical planning, and intra-operative guidance. The remaining challenge is to identify small bronchi correctly, which facilitates further segmentation of the pulmonary anatomies. METHODS...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-020-02293-x
更新日期:2021-01-19 00:00:00
abstract:PURPOSE:Interactive visualization is required to inspect and monitor the automatic segmentation of vessels derived from contrast-enhanced magnetic resonance angiography (CE-MRA). A dual-view visualization scheme consisting of curved planar reformation (CPR) and direct volume rendering (DVR) was developed for this purpo...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-010-0534-4
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Laser ablation of hard tissue is not completely understood until now and not modeled for computer-assisted microsurgery. A precise planning and simulation is an essential step toward the usage of microsurgical laser bone ablation in the operating room. METHODS:Planning the volume for laser bone ablation is bas...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-009-0303-4
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:C-arms are portable X-ray devices used to generate radiographic images in orthopedic surgical procedures. Evidence suggests that scouting images, which are used to aid in C-arm positioning, result in increased operation time and excess radiation exposure. C-arms are also primarily used qualitatively to view ima...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-020-02229-5
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:A personalized estimation of the cochlear shape can be used to create computational anatomical models to aid cochlear implant (CI) surgery and CI audio processor programming ultimately resulting in improved hearing restoration. The purpose of this work is to develop and test a method for estimation of the detai...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-017-1701-7
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:Most software systems for oral implantology are based on a two-dimensional multi-view approach, often accompanied with a surface rendered model. Usually they are affected by common errors like anisotropy of the volume and distortion on measurements. A more integrated and realistic 3D approach for implant surger...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-009-0394-y
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:Medical imaging and in particular digital radiographic images offer a great deal of information to dentists in the clinical diagnosis and treatment processes on a daily basis. This paper presents a new method aimed to produce an accurate segmentation of dental implants and the crestal bone line in radiographic ...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-012-0802-6
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:Deep brain stimulation (DBS) is a surgical procedure for treating motor-related neurological disorders. DBS clinical efficacy hinges on precise surgical planning and accurate electrode placement, which in turn call upon several image processing and visualization tasks, such as image registration, image segmenta...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-014-1007-y
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. METHODS:Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and ...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-013-0831-9
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:Regional infarction identification is important for heart disease diagnosis and management, and myocardial deformation has been shown to be effective for this purpose. Although tagged and strain-encoded MR images can provide such measurements, they are uncommon in clinical routine. On the contrary, cardiac CT i...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章,评审
doi:10.1007/s11548-016-1404-5
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:In the past decade, augmented reality systems have been expected to support surgical operations by making it possible to view invisible objects that are inside or occluded by the skull, hands, or organs. However, the properties of biological tissues that are non-rigid and featureless require a large number of d...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-016-1458-4
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Many diagnostic or treatment planning applications critically depend on the successful localization of bony structures in CT images. Manual or semiautomatic bone segmentation is tedious, however, and often not practical in clinical routine. In this paper, we present a reliable and fully automatic bone segmentat...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-018-1883-7
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:We aimed to investigate the feasibility of predicting invasion carcinoma from ductal carcinoma in situ (DCIS) lesions diagnosed by preoperative core needle biopsy using radiomics signatures, clinical imaging characteristics, and breast imaging reporting and data system (BI-RADS) descriptors on mammography. MET...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-018-1900-x
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Four-dimensional computed tomography (4DCT) images are often marred by artifacts that substantially degrade image quality and confound image interpretation. Human observation remains the standard method of 4DCT artifact evaluation, which is time-consuming and subjective. We develop a method to automatically ide...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-017-1538-0
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:Detection and segmentation of a brain tumor such as glioblastoma multiforme (GBM) in magnetic resonance (MR) images are often challenging due to its intrinsically heterogeneous signal characteristics. A robust segmentation method for brain tumor MRI scans was developed and tested. METHODS:Simple thresholds and...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-013-0922-7
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:Evaluation of circulating blood volume is important in assessing the status of patients. Although some studies have suggested that ultrasound images of the internal jugular vein (IJV) can be used for the analysis of circulating blood volume, accurate extraction of IJV is necessary to reduce errors. Therefore, t...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-013-0921-8
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:Multimodality mammography using conventional 2D mammography and dynamic contrast-enhanced 3D magnetic resonance imaging (DCE-MRI) is frequently performed for breast cancer detection and diagnosis. Combination of both imaging modalities requires superimposition of corresponding structures in mammograms and MR im...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-014-0976-1
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:Asymmetric stress imposed on the shoulder can lead to anterior shoulder instability in young athletes who perform repetitive overhead motions. A common treatment, surgical anterior capsule tightening, assumes that the instability is caused by abnormal anterior laxity. This study investigated the possibility tha...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-012-0782-6
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:Software-based devices have increasingly become an important part of several clinical scenarios. Due to their critical impact on human life, medical devices have very strict safety requirements. It is therefore necessary to apply verification methods to ensure that the safety requirements are met. Verificatio...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-013-0919-2
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:This paper proposes a method to predict the deflection of a flexible needle inserted into soft tissue based on the observation of deflection at a single point along the needle shaft. METHODS:We model the needle-tissue as a discretized structure composed of several virtual, weightless, rigid links connected by ...
journal_title:International journal of computer assisted radiology and surgery
pub_type: 杂志文章
doi:10.1007/s11548-015-1329-4
更新日期:2016-07-01 00:00:00