当前位置： SCI文献检索 > Advances in Medical Sciences期刊下所有文献 > Neuroimaging in assessment of risk of stroke in children with sickle cell disease.

Neuroimaging in assessment of risk of stroke in children with sickle cell disease.

Abstract：

PURPOSE:Stroke and subclinical "silent infarcts" are major causes of morbidity in children with Sickle Cell Disease (SCD). Ischemic strokes are more common in younger children while hemorrhagic strokes are more frequent in adults. The goal of neuroimaging in acute stroke is to document whether the stroke is ischemic or hemorrhagic, to assess the extent of parenchymal abnormalities and to determine the presence of other cerebrovascular lesions. Computed Tomography (CT) is the primary modality for the assessment of acute stroke patients because of its 24/7 availability and ability to exclude hemorrhagic causes. Magnetic resonance imaging (MRI) and MR angiography (MRA) are recommended to determine precisely extent of infarction and detect cerebrovascular abnormalities. The goal of neuroimaging in patients with hemorrhagic stroke is to identify an arteriovenous malformation or aneurysm(s) amenable to surgery or catheter intervention.The risk of first stroke is very high in asymptomatic children with intracranial arterial mean velocities over 200 cm/s on transcranial Doppler (TCD) examination. The risk can be substantially reduced if chronic blood transfusions are timely implemented. Large cerebral vessel disease detected by TCD can be confirmed or excluded by MRI/MRA. Those with evidence of parenchymal and/or cerebrovascular lesions should be followed by preventive therapy. In patients with neurologic symptoms and negative MRI/MRA findings Positron Emission Tomography or single photon emission CT is recommended. There are no specific neuroimaging findings that suggest that blood transfusions can be safely halted in children with SCD.

journal_name

Adv Med Sci

journal_title

Advances in medical sciences

authors

Arkuszewski M,Melhem ER,Krejza J

doi

10.2478/v10039-010-0045-0

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

115-29

issue

2

eissn

1896-1126

issn

1898-4002

pii

S1896-1126(14)60018-3

journal_volume

55

pub_type

杂志文章,评审

相关文献

Advances in Medical Sciences文献大全
  • Natural history and risk factors of long-term mortality in acute coronary syndrome patients with cardiogenic shock.

    abstract：PURPOSE:Cardiogenic shock (CS) is a severe complication of acute coronary syndromes (ACS). Intra-aortic balloon pump (IABP) is considered important mechanical therapy for acute CS. We aimed to analyze the natural history and possible prognostic factors in patients with CS complicating ACS. PATIENTS/METHODS:All 126 pat...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2013.12.003

    authors： Kamiński KA,Tycińska AM,Stepek T,Szpakowicz A,Olędzka E,Dobrzycki S,Musiał WJ

    更新日期：2014-09-01 00:00:00

  • Assessment of serum levels of DIO1 and DIO3 in patients diagnosed with COPD.

    abstract：PURPOSE:Chronic obstructive pulmonary disease is the most common chronic lung disease, which may be caused by different pathological processes, including inflammation. Furthermore, signs of changes in thyroid hormone levels are found in some patients. Deiodinases (DIOs) are selenoproteins (enzymes) involved in the synt...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2019.04.001

    authors： Gałecka E,Kumor-Kisielewska A,Górski P

    更新日期：2019-09-01 00:00:00

  • Expression of several long noncoding RNAs in peripheral blood mononuclear cells of patients with systemic lupus erythematosus.

    abstract：PURPOSE:Accumulating evidence has linked long noncoding RNAs (lncRNAs) to autoimmune and inflammatory disorders. This study aimed to detect the expression levels of five lncRNAs (lnc0640, lnc3643, lnc5150, lnc7514 and lncagf) in peripheral blood mononuclear cells (PBMCs) of patients with systemic lupus erythematosus (S...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2019.08.002

    authors： Wang JB,Li J,Zhang TP,Lv TT,Li LJ,Wu J,Leng RX,Fan YG,Pan HF,Ye DQ

    更新日期：2019-09-01 00:00:00

  • Concentrations of ssDNA in liver tissue and its correlation with sFas and sFasL in serum of patients infected with HBV, HCV, HCV and HIV.

    abstract：PURPOSE:The concentration of nucleic acids that undergo apoptosis (ssDNA) determines the actual activity of programmed cell death. ssDNA concentrations in liver tissue of patients with chronic HBV, HCV and HCV and HIV infections were assessed. The concentration of this nucleic acid was analyzed in relation to the conce...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：

    authors： Łapinski TW,Wiercińska-Drapało A,Panasiuk A,Kovalchuk O

    更新日期：2007-01-01 00:00:00

  • 24-hour esophageal pH monitoring in children with pathological acid gastroesophageal reflux: primary and secondary to food allergy. Part II. Intraesophageal pH values in proximal channel; preliminary study and control studies--after 1, 2, 4 and 9 years of

    abstract：PURPOSE:Among 264 children suspected of GERD, acid GER was confirmed in 138 children on the basis of 24-hour pH monitoring. AIMS OF THE STUDY:Comparative analysis of parameters of 24-hour intraesophageal pH monitoring with dual-channel probe (in proximal channel) in children with acid GER: primary and secondary to cow...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：

    authors： Semeniuk J,Kaczmarski M

    更新日期：2007-01-01 00:00:00

  • Diagnostic power of VEGF, MMP-9 and TIMP-1 in patients with breast cancer. A multivariate statistical analysis with ROC curve.

    abstract：PURPOSE:Vascular endothelial growth factor is an important factor in promoting angiogenesis in malignant processes, matrix metalloproteinase-9 in the degradation of extracellular matrix, which enhances metastasis, and tissue inhibitor of metalloproteinase-1 is its inhibitor. The aim of this study was to investigate the...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2018.07.002

    authors： Zajkowska M,Gacuta E,Kozłowska S,Lubowicka E,Głażewska EK,Chrostek L,Szmitkowski M,Pawłowski P,Zbucka-Krętowska M,Ławicki S

    更新日期：2019-03-01 00:00:00

  • Treatment of refractory epilepsy patients with autologous mesenchymal stem cells reduces seizure frequency: An open label study.

    abstract：PURPOSE:Existing anti-epileptic drugs (AED) have limited efficiency in many patients, necessitating the search for alternative approaches such as stem cell therapy. We report the use of autologous patient-derived mesenchymal stem cells (MSC) as a therapeutic agent in symptomatic drug-resistant epilepsy in a Phase I ope...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.advms.2016.12.004

    authors： Hlebokazov F,Dakukina T,Ihnatsenko S,Kosmacheva S,Potapnev M,Shakhbazau A,Goncharova N,Makhrov M,Korolevich P,Misyuk N,Dakukina V,Shamruk I,Slobina E,Marchuk S

    更新日期：2017-09-01 00:00:00

  • Specific inhibition of fibroblast activation protein (FAP)-alpha prevents tumor progression in vitro.

    abstract：PURPOSE:Solid tumors modulate their environment to keep non-malignant stromal cells in a tumor-promoting state. The main cells in the stroma of epithelial derived tumors are cancer associated fibroblasts (CAF) that are critical to tumorigenesis and angiogenesis. CAFs also supply the tumor cells with growth factors and ...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2015.04.006

    authors： Teichgräber V,Monasterio C,Chaitanya K,Boger R,Gordon K,Dieterle T,Jäger D,Bauer S

    更新日期：2015-09-01 00:00:00

  • Therapeutic strategy for autoimmune pancreatitis.

    abstract：:Autoimmune pancreatitis (AIP) is a particular type of pancreatitis that is thought to have an autoimmune etiology. Before therapy for AIP is begun, accurate diagnosis of AIP is necessary. It is important to distinguish AIP from pancreatic cancer. Since there is currently no diagnostic serological marker for AIP, AIP s...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章,评审

    doi：10.2478/v10039-008-0033-9

    authors： Kamisawa T,Satake K

    更新日期：2008-01-01 00:00:00

  • Analysis of the tumor necrosis factor superfamily member 11 gene polymorphism with bone mineral density and bone fracture frequency in patients with postmenopausal osteoporosis.

    abstract：PURPOSE:We aimed to examine the polymorphism of the promoter and exon 5 of the TNFSF11 gene and their impact on bone mineral density (BMD) and the frequency of bone fractures. TNFSF11 encodes the receptor activator of the NF-kB ligand (RANKL), a key regulator of bone metabolism and osteoporosis drug targets. BMD is an ...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2020.05.001

    authors： Wawrzyniak A,Skrzypczak-Zielinska M,Krela-Kazmierczak I,Michalak M,Marszalek D,Marcinkowska M,Zakerska-Banaszak O,Slomski R

    更新日期：2020-09-01 00:00:00

  • Parameters of the assessment of voice quality and clinical manifestation of rheumatoid arthritis.

    abstract：PURPOSE:The aim of the study was to investigate the voice quality parameters in 72 rheumatoid arthritis (RA) patients and their relationships with the clinical manifestations and disease activity. The control group consisted of 30 healthy subjects. MATERIAL AND METHODS:All RA patients were evaluated by extensive clini...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2015.06.004

    authors： Kosztyła-Hojna B,Moskal D,Kuryliszyn-Moskal A

    更新日期：2015-09-01 00:00:00

  • Magnetic resonance imaging of the cerebellum and brain stem in children with cerebral palsy.

    abstract：PURPOSE:The study aimed to examine the volumes of cerebellum and the brain stem in children with cerebral palsy (CP). MATERIAL AND METHODS:The present study included 21 children with spastic diplegic CP (11 girls and 10 boys). Twenty-one patients with CP were age- and gender-matched with the control patients. All subj...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：

    authors： Kułak W,Sobaniec W

    更新日期：2007-01-01 00:00:00

  • Iatrogenic femoral pseudoaneurysms - a simple solution of inconvenient problem?

    abstract：PURPOSE:A femoral artery pseudoaneurysm - is the most common complication associated with invasive coronary interventions. The aim of the study was to analyze the effectiveness of various methods used for femoral pseudoaneurysm treatment and to assess how routine use of radial approach leads to reduction of these site ...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-011-0027-x

    authors： Lisowska A,Knapp M,Usowicz-Szaryńska M,Kozieradzka A,Musial WJ,Dobrzycki S

    更新日期：2011-01-01 00:00:00

  • Utility of HE4 to identify patients with endometrioid endometrial cancer who may require lymphadenectomy.

    abstract：PURPOSE:The aim of the study was to establish whether preoperative serum levels of HE4 and CA125 could be a good predictor for lymphadenectomy in the early stage of endometrioid adenocarcinoma of the uterus. MATERIAL AND METHODS:Preoperative serum HE4 and CA125 were measured in 78 postmenopausal patients treated surgi...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2015.07.010

    authors： Dobrzycka B,Mackowiak-Matejczyk B,Terlikowska KM,Kinalski M,Terlikowski SJ

    更新日期：2016-03-01 00:00:00

  • Breast cancer expression of E-cadherin does not differ between patients with positive and negative oncological history.

    abstract：PURPOSE:The question of whether or not non-sporadic breast malignancies have different immunohistochemical features than sporadic malignancies has not been investigated previously. Consequently, the purpose of this study was to compare the expression of E-cadherin (EC) in breast cancer patients with positive and negati...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-008-0007-y

    authors： Bruzewicz S,Matkowski R,Swiatoniowski G,Suder E,Setta M,Połozowski A,Zychowicz K,Szynglarewicz B,Kornafel J

    更新日期：2008-01-01 00:00:00

  • Methoxy-stilbenes downregulate the transcription of Wnt/β-catenin-dependent genes and lead to cell cycle arrest and apoptosis in human T98G glioblastoma cells.

    abstract：PURPOSE:Glioblastoma is the most common and the deadliest brain cancer. The aim of this study was to analyze the impact of resveratrol and its five analogs: 3,4,4'-trimethoxy, 3,4,2'-trimethoxy, 3,4,2',4'-tetramethoxy, 3,4,2',6'-tetramethoxy and 3,4,2',4',6'-pentamethoxy-trans-stilbenes (MS) on human glioblastoma T98G ...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2020.11.001

    authors： Majchrzak-Celińska A,Zielińska-Przyjemska M,Wierzchowski M,Kleszcz R,Studzińska-Sroka E,Kaczmarek M,Paluszczak J,Cielecka-Piontek J,Krajka-Kuźniak V

    更新日期：2020-11-22 00:00:00

  • Correlation of B type natriuretic peptides with clinical and echocardiographic parameters in heterogeneous population of patients with symptoms suggestive of heart failure.

    abstract：PURPOSE:NT-proBNP and BNP concentrations in CHF correlate with NYHA class and LVEE Little research has been conducted to compare the clinical performance of these two natriuretic peptides in heterogeneous CHF population. Purpose: to evaluate and compare the clinical performance of NT-proBNP and BNP in heterogeneous gro...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：

    authors： Piechota WN,Piechota WT,Bejm J,Wierzbowski R,Michałkiewicz D

    更新日期：2006-01-01 00:00:00

  • Molecular profiles of non-small cell lung cancers in cigarette smoking and never-smoking patients.

    abstract：PURPOSE:Molecular features of non-small cell lung cancer (NSCLC) in never-smokers are not well recognized. We assessed the expression of genes potentially related to lung cancer etiology in smoking vs. never-smoking NSCLC patients. METHODS:We assayed frozen tumor samples from surgically resected 31 never-smoking and 5...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/ams-2013-0025

    authors： Szymanowska-Narloch A,Jassem E,Skrzypski M,Muley T,Meister M,Dienemann H,Taron M,Rosell R,Rzepko R,Jarząb M,Marjański T,Pawłowski R,Rzyman W,Jassem J

    更新日期：2013-01-01 00:00:00

  • Treatment of insulin dependent diabetes mellitus with intravascular transplantation of pancreatic islet cells without immunosuppressive therapy.

    abstract：PURPOSE:To evaluate intravascular xenotransplantation of macroencapsulated pancreatic islet cells in the process of the treatment of diabetes mellitus type 1 without immunosuppressive therapy. MATERIAL AND METHODS:Xenogenic intravascular transplantation was performed in 19 patients with diabetes mellitus (type 1) havi...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-008-0045-5

    authors： Prochorov AV,Tretjak SI,Goranov VA,Glinnik AA,Goltsev MV

    更新日期：2008-01-01 00:00:00

  • Myocardial perfusion and intima-media thickness in patients with subclinical hypothyroidism.

    abstract：PURPOSE:The data concerning the relation between subclinical hypothyroidism (SH) and the risk of cardiovascular disease are divergent. We aimed to assess myocardial perfusion in contrast-enhanced echocardiography and intima-media thickness (IMT) in patients with SH. MATERIAL/METHODS:Forty females with SH without sympt...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-012-0068-9

    authors： Knapp M,Lisowska A,Sobkowicz B,Tycińska A,Sawicki R,Musiał WJ

    更新日期：2013-01-01 00:00:00

  • Serum adiponectin level in obstructive sleep apnea: Relation of adiponectin to obesity and long-term continuous positive airway pressure therapy.

    abstract：PURPOSE:The study aimed to determine the effect of OSA and obesity on the plasma levels of adiponectin and the long-term effect of CPAP on its plasma levels and obesity parameters. MATERIAL/METHODS:A prospective observational study included 159 newly diagnosed OSA patients. The cohort was divided into CPAP treated (n=...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.1016/j.advms.2015.10.004

    authors： Hobzová M,Salzman R,Stejskal D,Zapletalová J,Kolek V

    更新日期：2016-03-01 00:00:00

  • Does the OPG/RANKL system contribute to the bone-vascular axis in chronic kidney disease? A systematic review.

    abstract：:Vascular calcification (VC) is highly prevalent in patients with chronic kidney disease (CKD) and is strongly associated with cardiovascular mortality and morbidity. Accumulating evidence over the past decade has challenged the hypothesis of close interaction between bone and VC what raises the possibility of a common...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.advms.2016.08.001

    authors： Znorko B,Oksztulska-Kolanek E,Michałowska M,Kamiński T,Pawlak K

    更新日期：2017-03-01 00:00:00

  • Diagnosis and therapy of gestational breast cancer: a review.

    abstract：PURPOSE:In spite of the general consensus on the issue, to point to major dilemmas which appear in this matter of multidisciplinary interest, and to review current concepts on how to achieve optimal diagnostic and therapeutic outcome. RESULTS:Recent literature data show that the rate of gestational breast cancer, acco...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章,评审

    doi：10.2478/v10039-008-0037-5

    authors： Fajdić J,Gotovac N,Hrgović Z,Fassbender WJ

    更新日期：2008-01-01 00:00:00

  • Variability of hepatitis C virus hypervariable region 1 (HVR-1) during the early phase of pegylated interferon and ribavirin therapy.

    abstract：PURPOSE:Genetic variability of hepatitis C virus (HCV) is considered to be an important factor defining viral pathogenesis, persistence and resistance to treatment. The aim of the present study was to characterize HCV genetic heterogeneity within a hypervariable region 1 (HVR-1) before and during the early period of pe...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-012-0024-8

    authors： Caraballo Cortés K,Laskus T,Bukowska-Ośko I,Pawełczyk A,Berak H,Horban A,Fic M,Radkowski M

    更新日期：2012-01-01 00:00:00

  • Serum and ascitic fluid serotonin levels and 5-hydroxyindoleacetic acid urine excretion in the liver of cirrhotic patients with encephalopathy.

    abstract：PURPOSE:The excess and deficit of serotonin can be the cause of somatic and mental disorders. The aim of this study was to evaluate serotonin levels in blood and ascitic fluid as well as excretion of 5-hydroxyindoleacetic acid (5-HIAA) in urine in patients with hepatic encephalopathy (HE). MATERIAL AND METHODS:The stu...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/ams-2013-0010

    authors： Chojnacki C,Walecka-Kapica E,Stepien A,Pawlowicz M,Wachowska-Kelly P,Chojnacki J

    更新日期：2013-01-01 00:00:00

  • Cell adhesion molecules in endometrial cancer - A systematic review.

    abstract：:Adhesive molecules are responsible for the cell-cell interaction and the surrounding intercellular environment creating normal tissue architecture. The role of adhesion proteins in cancer refers to angiogenesis, loss of tissue continuity, and deprivation of intercellular contact with the extracellular matrix, promotin...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章,评审

    doi：10.1016/j.advms.2019.08.003

    authors： Lewczuk Ł,Pryczynicz A,Guzińska-Ustymowicz K

    更新日期：2019-09-01 00:00:00

  • Cytotoxicity of Aspergillus strains isolated from the neonatal intensive care unit environment.

    abstract：PURPOSE:It is essential in the medical care for immunocompromised patients that the environment should create minimal infection risk. Particularly, it concerns fungal infections. Fungi belonging to the Aspergillus genus are second frequent group of nosocomial pathogens producing opportunistic infections. MATERIAL AND ...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-010-0039-y

    authors： Gniadek A,Macura AB,Twaruzek M,Grajewski J

    更新日期：2010-01-01 00:00:00

  • Distribution of interstitial cells of Cajal in the neurogenic urinary bladder of children with myelomeningocele.

    abstract：PURPOSE:C-kit positive interstitial cells of Cajal (ICCs) play an important role in the regulation of the smooth muscle motility, acting as pacemakers to provide the slow wave activity in various organs. Recent studies have shown that c-kit positive ICCs are widely distributed in the urinary tract of animals and humans...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/ams-2013-0002

    authors： Piaseczna-Piotrowska A,Dzieniecka M,Samolewicz E,Leśniak D,Kulig A

    更新日期：2013-01-01 00:00:00

  • Dental caries and total antioxidant status of unstimulated mixed whole saliva in patients aged 16-23 years.

    abstract：PURPOSE:The purpose of the studies performed was an attempt to establish a potential relationship between total antioxidant status of unstimulated whole saliva, patients' ages, oral hygiene status and dental caries. MATERIAL AND METHODS:The study involved 120 non-smokers. Mean age of the study subjects was 18.40 ± 1.7...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-012-0015-9

    authors： Krawczyk D,Sikorska-Jaroszyńska MH,Mielnik-Błaszczak M,Pasternak K,Kapeć E,Sztanke M

    更新日期：2012-06-01 00:00:00

  • BAL fluid cells and pulmonary function in different radiographic stages of newly diagnosed sarcoidosis.

    abstract：PURPOSE:Sarcoidosis affected lungs detected in more than 90% of patients. The relationship between different stages of pulmonary sarcoidosis and pulmonary function tests (PFT) as well as bronchoalveolar lavage fluid (BALF) cells can be established. Geographic and ethnic factors are known to be linked to the specific ch...

    journal_title：Advances in medical sciences

    pub_type： 杂志文章

    doi：10.2478/v10039-008-0014-z

    authors： Danila E,Jurgauskiene L,Malickaite R

    更新日期：2008-01-01 00:00:00