Intertwined αβ spectrin meeting helical actin protofilament in the erythrocyte membrane skeleton: wrap-around vs. point-attachment.

abstract：:Poor prosthetic fit is often the result of heterotopic ossification (HO), a frequent problem following blast injuries for returning service members. Osseointegration technology offers an advantage for individuals with significant HO and poor socket tolerance by using direct skeletal attachment of a prosthesis to the d...

journal_title：Annals of biomedical engineering

authors： Isaacson BM,Stinstra JG,MacLeod RS,Pasquina PF,Bloebaum RD

更新日期：2010-09-01 00:00:00

abstract：:Tumor vasculature damage induced by various thermal treatments has been studied in vivo via laser confocal microscopy. Murine mammary carcinoma 4T1 was implanted in the nude mice dorsal skin fold window chamber. The implanted tumor was treated by alternate cooling and heating. Results showed that the treatment was muc...

journal_title：Annals of biomedical engineering

authors： Shen Y,Liu P,Zhang A,Xu LX

更新日期：2008-08-01 00:00:00

abstract：:While viscoelastic responses of isolated trunk soft tissues have been characterized in earlier studies, the effects of external loading and flexion rate on these responses in the intact human trunk are largely unknown. Two experiments were conducted to measure trunk viscoelastic behaviors, one involving prolonged flex...

journal_title：Annals of biomedical engineering

authors： Toosizadeh N,Nussbaum MA

更新日期：2013-06-01 00:00:00

abstract：:In recent years, advances in computing power and computational methods have made it possible to perform detailed simulations of the coronary artery stenting procedure and of related virtual tests of performance (including fatigue resistance, corrosion and haemodynamic disturbance). Simultaneously, there has been a gro...

journal_title：Annals of biomedical engineering

authors： Bressloff NW,Ragkousis G,Curzen N

更新日期：2016-02-01 00:00:00

abstract：:In order to successfully use a model for parameter identification, it must be carefully analyzed. Current analysis methods, however, are ad hoc and provide only partial information. We extended these methods through the application of stacked dimensions, a scientific visualization method. The end result of our extensi...

journal_title：Annals of biomedical engineering

authors： Bosan S,Harris TR

更新日期：1996-01-01 00:00:00

abstract：:In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

journal_title：Annals of biomedical engineering

authors： Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

更新日期：2007-01-01 00:00:00

abstract：:In this paper, we aim to establish a new mathematical model that relates pulse wave velocity (PWV) to blood pressure (BP) for continuous and noninvasive BP measurement. For the first time, we derive an ordinary differential equation (ODE) expressing the fundamental relation between BP, elastic modulus G and PWV. The g...

journal_title：Annals of biomedical engineering

authors： Chen Y,Wen C,Tao G,Bi M,Li G

更新日期：2009-11-01 00:00:00

abstract：:A coculture of endothelial cells (ECs) and smooth muscle cells (SMCs), which mimics cellular interactions appearing in vivo, has been performed in studies on the relationship between atherogenesis and fluid shear stress conditions. Although healthy arteries in vivo consist of contractile phenotype SMCs, cultured cells...

journal_title：Annals of biomedical engineering

authors： Sakamoto N,Kiuchi T,Sato M

更新日期：2011-11-01 00:00:00

abstract：:We present a method of measuring force response of a single living cell, attached to a substrate, in situ, by a functionalized microelectromechanical systems sensor that applies local deformation on the cell. The sensor is a single crystal silicon microcantilever beam with prescribed shape and geometry, and is coated ...

journal_title：Annals of biomedical engineering

authors： Saif MT,Sager CR,Coyer S

更新日期：2003-09-01 00:00:00

abstract：:Past literature has provided evidence that a normal mechanical force environment of blood flow may guide normal development while an abnormal environment can lead to congenital malformations, thus warranting further studies on embryonic cardiovascular flow dynamics. In the current study, we developed a non-invasive 4D...

journal_title：Annals of biomedical engineering

authors： Ho S,Tan GXY,Foo TJ,Phan-Thien N,Yap CH

更新日期：2017-10-01 00:00:00

abstract：:Blunt carotid artery injuries occur in 0.3% of blunt injured patients and may lead to devastating neurological consequences. However, arterial mechanics leading to internal layer subfailure have not been quantified. Twenty-two human carotid artery segments and 18 porcine thoracic aorta segments were opened to expose t...

journal_title：Annals of biomedical engineering

authors： Stemper BD,Yoganandan N,Sinson GP,Gennarelli TA,Stineman MR,Pintar FA

更新日期：2007-02-01 00:00:00

abstract：:Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered because of limited understanding of the mechanisms by which they respond to environmental stimuli. Efforts to understand extracellular biophysical cues have demonstrated the critical roles of ...

journal_title：Annals of biomedical engineering

authors： Piroli ME,Jabbarzadeh E

更新日期：2018-06-01 00:00:00

abstract：:Measurement of the instantaneous pressure-volume relationship of the left ventricle is fundamental to the study of ventricular mechanics. In order to effectively investigate this relationship, it is necessary to vary and control the time course of ventricular volume change in a variety of prescribed manners. In the pa...

journal_title：Annals of biomedical engineering

authors： Sunagawa K,Lim KO,Burkhoff D,Sagawa K

更新日期：1982-01-01 00:00:00

abstract：:Continuum-level finite element models (FEMs) of the humerus offer the ability to evaluate joint replacement designs preclinically; however, experimental validation of these models is critical to ensure accuracy. The objective of the current study was to quantify experimental full-field strain magnitudes within osteoar...

journal_title：Annals of biomedical engineering

authors： Kusins J,Knowles N,Columbus M,Oliviero S,Dall'Ara E,Athwal GS,Ferreira LM

更新日期：2020-12-01 00:00:00

abstract：:Glaucoma is a common optic neuropathy characterized by retinal ganglion cell death. Elevated intraocular pressure (IOP), a key risk factor for glaucoma, leads to significant biomechanical deformation of optic nerve head (ONH) cells and tissues. ONH astrocytes respond to this deformation by transforming to a reactive, ...

journal_title：Annals of biomedical engineering

authors： Mulvihill JJE,Raykin J,Snider EJ,Schildmeyer LA,Zaman I,Platt MO,Kelly DJ,Ethier CR

更新日期：2018-02-01 00:00:00

abstract：:This is a personal historical essay on meanderings through the jungle of the microcirculatory swamp. Because one pretends that the wandering was purposefully exploratory, a few guideposts are placed at positions where one could discern blaze-marks from earlier wanderers, and the path cut a little wider along some of t...

journal_title：Annals of biomedical engineering

authors： Bassingthwaighte JB

更新日期：1987-01-01 00:00:00

abstract：:Accurate identification of contracting muscles can help us to understand the muscle function in both physiological and pathological conditions. Conventional electromyography (EMG) have limited access to deep muscles, crosstalk, or instability in the recordings. Accordingly, a novel framework was developed to detect co...

journal_title：Annals of biomedical engineering

authors： Zheng Y,Shin H,Kamper DG,Hu X

更新日期：2021-01-01 00:00:00

abstract：:This study presents a new steady-state visual evoked potential (SSVEP)-based brain computer interface (BCI). SSVEPs, induced by phase-tagged flashes in eight light emitting diodes (LEDs), were used to control four cursor movements (up, right, down, and left) and four button functions (on, off, right-, and left-clicks)...

journal_title：Annals of biomedical engineering

authors： Lee PL,Sie JJ,Liu YJ,Wu CH,Lee MH,Shu CH,Li PH,Sun CW,Shyu KK

更新日期：2010-07-01 00:00:00

abstract：:Collagen, the most commonly used extra-cellular matrix protein for tissue engineering applications, displays poor mechanical properties. Here, we report on the preparation and characterization of novel multi-component composite systems that incorporate a genetically engineered, biocompatible polymer (elastin-like poly...

journal_title：Annals of biomedical engineering

authors： Wheeler TS,Sbravati ND,Janorkar AV

更新日期：2013-10-01 00:00:00

abstract：:In the field of fluid flow within the human body, focus has been placed on the transportation of blood in the systemic circulation since the discovery of that system; but, other fluids and fluid flow phenomena pervade the body. Some of the most fascinating fluid flow phenomena within the human body involve fluids othe...

journal_title：Annals of biomedical engineering

authors： Zamir M,Moore JE Jr,Fujioka H,Gaver DP 3rd

更新日期：2010-03-01 00:00:00

abstract：:Auscultation is an important diagnostic indicator for cardiovascular analysis. Heart sound classification and analysis play an important role in the auscultative diagnosis. This study uses a combination of Mel-frequency cepstral coefficient (MFCC) and hidden Markov model (HMM) to efficiently extract the features for p...

journal_title：Annals of biomedical engineering

authors： Wang P,Lim CS,Chauhan S,Foo JY,Anantharaman V

更新日期：2007-03-01 00:00:00

abstract：:Asymmetric 75% and 95% area reduction, transparent Sylgard stenotic models were operated under internal carotid artery (ICA) [Womersley parameter, alpha=5.36, Re(mean) =213 and 180, respectively, and Re(peak)=734 and 410, respectively] and left anterior descending coronary artery (LAD) flow wave forms (alpha=2.65, Re(...

journal_title：Annals of biomedical engineering

authors： Cao J,Rittgers SE

更新日期：1998-03-01 00:00:00

abstract：:There are a number of cell therapies that are either in clinical trials or moving toward clinical trials, particularly for diseases of the retina. One of the challenges with cell therapies is tracking the status of cells over time. Genetic manipulation can facilitate this, but it can limit the clinical application of ...

journal_title：Annals of biomedical engineering

authors： Bolger M,Groynom R,Bogie K,Lavik E

更新日期：2020-07-01 00:00:00

abstract：:Tissue engineering strategies have utilized a wide spectrum of synthetic and naturally-derived scaffold materials. Synthetic scaffolds are better defined and offer the ability to precisely and reproducibly control their properties, while naturally-derived scaffolds typically have inherent biological and structural pro...

journal_title：Annals of biomedical engineering

authors： Allen AB,Priddy LB,Li MT,Guldberg RE

更新日期：2015-03-01 00:00:00

abstract：:The strength between the cortical screw and bone following an orthopaedic implant surgery is an important determinant for the success of osteosynthesis. An excessive axial cutting force during drilling produces microcracks in the bone surface, resulting in reduced strength between the screw and bone, resulting in loos...

journal_title：Annals of biomedical engineering

authors： Singh RP,Gupta V,Pandey PM,Mridha AR

更新日期：2021-01-01 00:00:00

abstract：:Continued progress in the field of Brain Interface (BI) research has encouraged the rapid expansion of the BI community over the last two decades. As the number of BI researchers and organizations steadily increases, newer and more advanced technologies are constantly produced, evaluated, and reported. Though the BI c...

journal_title：Annals of biomedical engineering

authors： Jackson MM,Mason SG,Birch GE

更新日期：2006-05-01 00:00:00

abstract：:A kinetic model based on first principles, for β(2)-microglobulin, is presented to obtain precise parameter estimates for individual patient. To reduce the model complexity, the number of model parameters was reduced using a priori identifiability analysis. The model validity was confirmed with the clinical data of te...

journal_title：Annals of biomedical engineering

authors： Maheshwari V,Samavedham L,Rangaiah GP

更新日期：2011-12-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:Functional electrical stimulation (FES) to lower extremity (LE) muscles is used by individuals post-stroke as an alternative to mechanical orthotic devices during gait or as a training modality during rehabilitation. Technological developments which improve the feasibility, accessibility and effectiveness of FES syste...

journal_title：Annals of biomedical engineering

authors： Kafri M,Laufer Y

更新日期：2015-02-01 00:00:00

abstract：:Further understanding of the mechanical deformation and tear behavior of kidney during suturing helps to enhance surgical task execution that requires fine suture manipulation. This paper aims to develop a model to describe the relationship between the tensile force acting on suture line and the resulted kidney deform...

journal_title：Annals of biomedical engineering

authors： Yu D,Qing Y,Jianxun Z,Jun D

更新日期：2013-04-01 00:00:00