Abstract:
:In order to successfully use a model for parameter identification, it must be carefully analyzed. Current analysis methods, however, are ad hoc and provide only partial information. We extended these methods through the application of stacked dimensions, a scientific visualization method. The end result of our extensions are multi-dimensional parametric model-images. These images depict a model as a function of all its parameters in a single graphic. We applied parametric model-images to model verification (behavioral analysis), sensitivity analysis, and identifiability analysis. We applied our methodology to the evaluation of pulmonary vascular capillary-transport models. Results have shown that the visualization-based method provides a more complete view of a model's behavior and its other characteristics. Furthermore, our method has also proven to be more computationally efficient than the traditional approaches.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Bosan S,Harris TRdoi
10.1007/BF02771001subject
Has Abstractpub_date
1996-01-01 00:00:00pages
124-38issue
1eissn
0090-6964issn
1573-9686journal_volume
24pub_type
杂志文章abstract::A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02584215
更新日期:1983-01-01 00:00:00
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journal_title:Annals of biomedical engineering
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doi:10.1007/s10439-014-1086-5
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journal_title:Annals of biomedical engineering
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-005-8338-3
更新日期:2005-12-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-010-9977-6
更新日期:2010-06-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-008-9467-2
更新日期:2008-04-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-005-2867-7
更新日期:2005-06-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1114/1.1355278
更新日期:2001-03-01 00:00:00
abstract::Bending stiffness of passive-dynamic ankle-foot orthoses (PD-AFOs) is a functional characteristic thought to restore lost ankle function due to weakened plantar flexors. However, lower extremity impairment profiles of patients are seldom limited to plantar flexion weakness, and PD-AFO characteristics often influence g...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-014-1067-8
更新日期:2015-02-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-005-8967-6
更新日期:2005-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-020-02655-1
更新日期:2020-10-20 00:00:00
abstract::Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall constituents. In this study, planar biaxial tensile test data of elastase-treated porcine aortic tissue (Chow et ...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-012-0733-y
更新日期:2013-07-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-010-9937-1
更新日期:2010-06-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-020-02627-5
更新日期:2020-11-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1114/1.1312184
更新日期:2000-09-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-013-0948-6
更新日期:2014-04-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-019-02398-8
更新日期:2020-07-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-010-9912-x
更新日期:2010-03-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02584303
更新日期:1991-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-007-9255-4
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journal_title:Annals of biomedical engineering
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journal_title:Annals of biomedical engineering
pub_type: 社论
doi:10.1007/s10439-020-02599-6
更新日期:2020-10-01 00:00:00
abstract::The bending stiffness of a phospholipid bilayer (Kc) was measured by forming thin bilayer cylinders (tethers) from giant phospholipid vesicles. Based on the balance of forces, the tether force was expected to be proportional to the square root of the membrane tension, with a constant of proportionality containing Kc. ...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02684228
更新日期:1996-09-01 00:00:00
abstract::This paper outlines a comprehensive parametric approach for quantifying mechanical properties of spatially heterogeneous thin biological specimens such as human breast tissue using contact-mode Atomic Force Microscopy. Using inverse finite element (FE) analysis of spherical nanoindentation, the force response from hyp...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-014-1057-x
更新日期:2014-09-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02368460
更新日期:1991-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-010-0148-6
更新日期:2010-11-01 00:00:00
abstract::Depending on the duration of exposure to supraphysiological temperatures, cellular proteins and organelles can suffer from structural alternations and irreversible denaturation, which may induce cell death. The thermotolerance of three human urinary bladder carcinoma cell lines, TSGH-8301, J82 and TCC-SUP (cytological...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-009-9773-3
更新日期:2009-11-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-005-2513-4
更新日期:2005-04-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-010-9972-y
更新日期:2010-07-01 00:00:00