Renin-Angiotensin-Aldosterone System and Migraine: A Systematic Review of Human Studies.

abstract：BACKGROUND:Radical Probe Mass Spectrometry (RP-MS) describes a pioneering methodology in structural biology that enables the study of protein structures, their interactions, and dynamics on fast timescales (down to sub-milliseconds). Hydroxyl radicals (•OH) generated directly from water within aqueous solutions induce ...

journal_title：Protein and peptide letters

authors： Maleknia SD,Downard KM

更新日期：2019-01-01 00:00:00

abstract：:Structural-energetic analysis of peptide and protein antigens in the context of binding to antibody reveals fundamental differences between the cross-reactions of antipeptide antibody with protein and antiprotein antibody with peptide, providing a physicochemical basis for B-cell epitope prediction as applied to the d...

journal_title：Protein and peptide letters

authors： Caoili SE

更新日期：2006-01-01 00:00:00

abstract：:Natural, synthetic and analogues of peptides have shown prospects for application in cancer chemotherapy. Notably, some food protein-derived peptides are known to possess anticancer activities in cultured cancer cells, and also in animal cancer models via different mechanisms including induction of apoptosis, cell cyc...

journal_title：Protein and peptide letters

authors： Rajendran SR,Ejike CE,Gong M,Hannah W,Udenigwe CC

更新日期：2017-01-01 00:00:00

abstract：:The small heat shock protein SsHSP14.1 from the hyper-thermophilic archeaon, Sulfolobus solfataricus (S. solfataricus) was able to protect proteins from thermal aggregation and prevent enzymes from heat induced inactivation. According to the 3D (dimensional) structural model of SsHSP14.1 developed by us before, the re...

journal_title：Protein and peptide letters

authors： Wen ZZ,Wang YH,Yang B,Xie MQ,Chou KC

更新日期：2011-03-01 00:00:00

abstract：:Hop is a tetratricopeptide repeat domain (TPR)-containing co-chaperone that is able to directly associate with both Hsp70 and Hsp90. Previous data showed that the TPR2A-domain is the primary site for dimerization and that the TPR2B-domain may also play a role in dimerization. We present Hop-D456G, a mutant within the ...

journal_title：Protein and peptide letters

authors： Gonçalves DC,Gava LM,Ramos CH

更新日期：2010-04-01 00:00:00

abstract：:Sry-related box (Sox) transcription factors share a conserved high-mobility-group box domain (HMG-domain) that binds DNA in the minor groove and bends DNA for further assembly of transcriptional machineries. During organogenesis, each member of the Sox family triggers a specific cell lineage differentiation, indicatin...

journal_title：Protein and peptide letters

authors： Gao N,Jiang W,Gao H,Cheng Z,Qian H,Si S,Xie Y

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:NMAAP1 plays a role in regulating macrophage differentiation to the M1 type and exerting antitumoral functions. It is not clear what role and mechanism NMAAP1 does play in the reversal of macrophages from M1 to M2. METHODS:We detected the typing of macrophages with high or low expression of NMAAP1 by QPCR a...

journal_title：Protein and peptide letters

authors： Liu Q,Zhu P,Liu S,Tang M,Wang Y,Tian Y,Jin Z,Li D,Yan D

更新日期：2019-01-01 00:00:00

abstract：:In eukaryotic cells, regulated protein degradation of intracellular proteins is mediated largely by the ubiquitin proteasome system (UPS). UPS-mediated protein degradation regulates virtually all crucial aspects of cellular physiology, such as cell proliferation, cell division, cell differentiation, and cell death. Co...

journal_title：Protein and peptide letters

authors： Eldeeb M,Fahlman R

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Cryptochrome is a flavin-binding blue-light photoreceptor that functions in growth and development in plants, the circadian clock in animals and navigation in birds. However, a lack of purified cryptochrome has hindered studies of the structure and function of this protein. In this study, we obtained a subst...

journal_title：Protein and peptide letters

authors： Yuan X,Wang W,Wu W,Wang J

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:In this investigation a novel approach based on mucoadhesive superporous hydrogel hybrids (SPHHs) for topi- cal vaginal drug delivery for Metronidazole was tried. METHOD:SPHHs were synthesized by solution polymerization tech- nique. The synthesized SPHHs were characterized for tensile strength, swelling beh...

journal_title：Protein and peptide letters

authors： Chavda H,Chavada G,Patel J,Rangpadiya K,Patel C

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to design and develop stable nanoemulsion formulations containing IFN-γ to probe their use as an immunomodulating agent. The nanoemulsions comprising distilled water, triglycerides of capric acid/caprylic, sobitan-oleate (SP), polysorbate 80 (TW) and propylene glycol (PG) were prepared throug...

journal_title：Protein and peptide letters

authors： Ribeiro EB,Honorio-França AC,França EL,Soler MA

更新日期：2016-01-01 00:00:00

abstract：:A new coding sequence of the procarboxypeptidase B gene was obtained from SD rat fresh pancreas by RT-PCR and highly expressed in Escherichia coli in inclusion bodies. The folded procarboxypeptidase B was subjected to trypsin enzymatic cleavage to produce active carboxypeptidase B, subsequently, carboxypeptidase B was...

journal_title：Protein and peptide letters

authors： Su-Xia L,Yu-Jian Z,Li-Ping T,Qin-Sheng Y,Yi G

更新日期：2003-12-01 00:00:00

abstract：:A recombinant human parathyroid hormone (rhPTH) fragment (Gly1-Gln26-rhPTH(1-34)) which contains two amino acids substitutions (Gly1 and Gln26) was acquired through Escherichia coli expression system using a soluble fusion protein strategy. The soluble fusion protein MBP-Gly1-Gln26-rhPTH(1-34) was harvested after puri...

journal_title：Protein and peptide letters

authors： Xu XC,Zhong SD,Kai F,Li LR,Liu C,Liu B,Bao JK

更新日期：2008-01-01 00:00:00

abstract：:We have studied the effect of guanidinium chloride (Gdn.Cl) and different osmolytes such as betaine, trimethylamine-N-oxide (TMAO) and urea on the rate of chymotrypsin catalyzed reaction. The rates were measured using three synthetic chromogenic substrates, succinyl-ala-ala-pro-arg-pNA (AAPR), succinyl-ala-ala-pro-leu...

journal_title：Protein and peptide letters

authors： Garringer M,Qasim MA

更新日期：2016-01-01 00:00:00

abstract：:Coiled coils are important structural modules and domains of protein-protein interactions. Further, they provide the required framework to proteins, like kinesins, myosins and SNAREs, which are either structural or involved in transport of biomolecules. We provide an interactive webserver to measure the strength of in...

journal_title：Protein and peptide letters

authors： Alva V,Syamala Devi DP,Sowdhamini R

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Development of proteins and peptides into drugs has been considered as a promising strategy to target certain diseases. However, only few proteins and peptides have been approved as new drugs into the market each year. One major problem is that proteins and peptides often exhibit short plasma half-life times...

journal_title：Protein and peptide letters

authors： Wu H,Huang J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Recently, the small molecule that inhibits the human copper-trafficking proteins Atox1 and CCS was reported, which suggested that small molecule has an effect on the copper regulation system in the cell. The copper chaperones CopC is regarded as a redox switch and possess barrel structure, thus the interacti...

journal_title：Protein and peptide letters

authors： Song Z,Liu J,Yuan W,Bai Z,Gao N

更新日期：2020-01-01 00:00:00

abstract：:Glycation, a non-enzymatic reaction between glucose and protein is the primary cause of diabetic complications. Albumin, the most abundant plasma protein undergoes glycation both in vivo and in vitro. The influence of albumin on glycation of less abundant proteins has not been addressed. For the first time, we show th...

journal_title：Protein and peptide letters

authors： Bhonsle HS,Singh SK,Srivastava G,Boppana R,Kulkarni MJ

更新日期：2008-01-01 00:00:00

abstract：:Increasing antibiotic resistance has led to an urgent need for new therapeutic approaches. Host defense peptides are known to be antimicrobial and have revealed broad immunomodulatory functions for both innate and adaptive immunity. This review will focus on the role of host defense peptides in infection and immune re...

journal_title：Protein and peptide letters

authors： Hirsch T,Jacobsen F,Steinau HU,Steinstraesser L

更新日期：2008-01-01 00:00:00

abstract：:The present paper reviews the use of expressed protein ligation for the biosynthesis of backbone cyclized polypeptides. This general method allows the in vivo and in vitro biosynthesis of cyclic polypeptides using recombinant DNA expression techniques. Biosynthetic access to backbone cyclic peptides opens the possibil...

journal_title：Protein and peptide letters

authors： Kimura R,Camarero JA

更新日期：2005-11-01 00:00:00

abstract：:Application of complementary B and T cell epitopes in inducing anti-idiotypic and anti-clonotypic antibodies capable of regulating or suppressing the autoimmune responses in experimental autoimmune myasthenia gravis (EAMG), allergic neuritis (EAN) and allergic encephalomyelitis (EAE) has been the stimulus of many rese...

journal_title：Protein and peptide letters

authors： Sakarellos-Daitsiotis M,Cung MT,Sakarellos C,El Hilali Z,Kosmopoulou A,Voitharou C

更新日期：2004-08-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) are short, cationic, membrane-interacting proteins that exhibit broad-spectrum antimicrobial activity, and are hence of significant biomedical interest. They exert their activity by selectively binding to and lysing target cell membranes, but the precise molecular details of their mechani...

journal_title：Protein and peptide letters

authors： Bond PJ,Khalid S

更新日期：2010-11-01 00:00:00

abstract：:Identification on protein folding types is always based on the 27-class folds dataset, which was provided by Ding & Dubchak in 2001. But with the avalanche of protein sequences, fold data is also expanding, so it will be the inevitable trend to improve the existing dataset and expand more folding types. In this paper,...

journal_title：Protein and peptide letters

authors： Liu L,Hu XZ,Liu XX,Wang Y,Li SB

更新日期：2012-04-01 00:00:00

abstract：:In this article we review the current status of our understanding of membrane mediated interactions from theory and experiment. Phenomenological mean field and molecular models will be discussed and compared to recent experimental results from dynamical neutron scattering and atomic force microscopy. ...

journal_title：Protein and peptide letters

authors： Armstrong CL,Sandqvist E,Rheinstädter MC

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:A core sequence (the 9 C-terminal residues) of calcification-associated peptide (CAP- 1) isolated from the exoskeleton of the red swamp crayfish was previously shown to control calcium carbonate precipitation with chitin. In addition, a modified core sequence in which the phosphorylated serine at the N termi...

journal_title：Protein and peptide letters

authors： Usui K,Yokota SI,Ozaki M,Sakashita S,Imai T,Tomizaki KY

更新日期：2018-01-01 00:00:00

abstract：:Endonuclease tRNase Z catalyzes the generation of the mature 3' end of tRNA precursors through specific endonucleolytic cleavage. The enzyme has been characterized from organisms representative of all domains of life as well as from organelles, and the crystal structure of three bacterial enzymes has been determined. ...

journal_title：Protein and peptide letters

authors： Ceballos M,Vioque A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:OPT3s are involved in the transport of Fe from xylem to phloem, in loading Fe into phloem, and in the transmission of shoot-to-root iron signaling. Yet, apart from Arabidopsis, little is known about these transporters'functions in other plant species. OBJECTIVE:OPT3 proteins of several plant species were ch...

journal_title：Protein and peptide letters

authors： Kurt F

更新日期：2020-06-25 00:00:00

abstract：:Adenoregulin is a 33 amino acid antibiotic peptide who belongs to dermaseptin family which is the first vertebrate family to show lethal effects against filamentous fungi, as well as a broad spectrum of pathogenic microorganisms. Synthetic adenoregulin gene was cloned in 2, 4 and 6 tandem repeats and subcloned in pET3...

journal_title：Protein and peptide letters

authors： Zhou Y,Cao W,Wang J,Ma Y,Wei D

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Chickpea is a widely grown legume in India, Australia, Canada, and Mediterranean regions. Seeds of chickpea are good source of protein for both human and animals. Wild relatives of chickpea (Cicer arietinum) are the potential gene pool for crop improvement; however, very little information is available on th...

journal_title：Protein and peptide letters

authors： Dhar S,Bhattacharjee M,Acharjee S,Baishya D

更新日期：2020-09-10 00:00:00

abstract：:With a huge amount of protein sequence data, the computational method for protein-protein interaction (PPI) prediction using only the protein sequences information have drawn increasing interest. In this article, we propose a sequence-based method based on a novel representation of local protein sequence descriptors. ...

journal_title：Protein and peptide letters

authors： Yang L,Xia JF,Gui J

更新日期：2010-09-01 00:00:00