Protein-protein interactions in membranes.

abstract：:A novel cellulase was isolated from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius ATCC27009 grown in medium containing carboxymethylcellulose. The enzyme is a glycosylated monomer of 56.2 kDa, relatively thermostable, with optimal pH and temperature of 4.0 and 65 degrees C, respectively. Enzymatic as...

journal_title：Protein and peptide letters

authors： Morana A,Esposito A,Maurelli L,Ruggiero G,Ionata E,Rossi M,La Cara F

更新日期：2008-01-01 00:00:00

abstract：:The cytotoxicity of hPrP[173-195] prion peptide against a neuroblastoma cell model was found independent of its tendency to aggregate over time. Cytosolic and nuclear inclusions of peptide were highlighted by confocal microscopy, suggesting a role as a transcription factor in activating signal transduction pathways in...

journal_title：Protein and peptide letters

authors： Urso E,Acierno R,Lionetto MG,Rizzello A,Papa A,Schettino T,Maffia M

更新日期：2009-01-01 00:00:00

abstract：:Phoenixin (PNX), a newly identified peptide cleaved from the C-terminus of protein C4orf52, mainly exists in two active isoforms, phoenixin-14 (PNX-14) amide and phoenixin-20 (PNX-20) amide that were first isolated from the rat hypothalamus and bovine heart, respectively. Initial studies demonstrated that PNX is a rep...

journal_title：Protein and peptide letters

authors： Yuan T,Sun Z,Zhao W,Wang T,Zhang J,Niu D

更新日期：2017-01-01 00:00:00

abstract：:VML is a lectin from Vatairea macrocarpa seeds that has various biological activities. Here, we describe three new lectin isoforms from V. macrocarpa identified through genomic DNA analysis. One of these isoforms has high similarity to VML, while another that has noteworthy differences. We have denoted the new isoform...

journal_title：Protein and peptide letters

authors： Alves Filho JG,do Nascimento AS,Gondim AC,Pereira RH,da Cunha RM,Nagano CS,Teixeira EH,Nascimento KS,Cavada BS

更新日期：2013-11-01 00:00:00

abstract：:To investigate the processing of transforming growth factor beta1 (TGFbeta1) pro-protein by furin protease we expressed a GST-pro-TGFbeta1 fusion protein in bacteria. Analysis of the furin digestion pattern revealed the liberation of 12.5 kDa TGFbeta1 monomers. There was no evidence for cleavage of an alternative furi...

journal_title：Protein and peptide letters

authors： Kahle NA,Joffroy C,Popp SL,Knabbe C,Stope MB

更新日期：2010-04-01 00:00:00

abstract：:We present two efficient network propagation algorithms that operate on a binary tree, i.e., a sparse-edged substitute of an entire similarity network. TreeProp-N is based on passing increments between nodes while TreeProp-E employs propagation to the edges of the tree. Both algorithms improve protein classification e...

journal_title：Protein and peptide letters

authors： Kocsor A,Busa-Fekete R,Pongor S

更新日期：2008-01-01 00:00:00

abstract：:ROS, including (.)OH, is now recognized as the hallmark of inflammation and damage to the anti-proteinase barrier has been implicated in a number of pathophysiological conditions. We have previously shown that O2( -) and H2O2/HOCl are physiologically relevant inactivators of alpha 2M, a key anti-proteinase. Here, we s...

journal_title：Protein and peptide letters

authors： Khan SA,Khan FH

更新日期：2009-01-01 00:00:00

abstract：:Comparison between the BAD complexes indicated that BAD all docks a hydrophobic surface of PKAc regardless of its phosphorylation. PKAc may prevent Bcl-xL from rebinding to BAD by phosphorylating human BAD at Ser118; whereas human BAD is phosphorylated on Ser75 in a BAD-Bcl-xL complex, resulting in the dissociation of...

journal_title：Protein and peptide letters

authors： Yang J

更新日期：2010-02-01 00:00:00

abstract：:The description of protein backbone was recently improved with a group of structural fragments called Structural Alphabets instead of the regular three states (Helix, Sheet and Coil) secondary structure description. Protein Blocks is one of the Structural Alphabets used to describe each and every region of protein bac...

journal_title：Protein and peptide letters

authors： Suresh V,Ganesan K,Parthasarathy S

更新日期：2013-03-01 00:00:00

abstract：:Heparin is naturally occurring polysaccharides which interacts with seminal plasma proteins and regulate multiple steps in fertilization process. Qualitative and quantitative information regarding the affinity for heparin-seminal plasma proteins interactions is not generally well documented and there are no reports of...

journal_title：Protein and peptide letters

authors： Kumar V,Yadav VK,Hassan MI,Singh AK,Dey S,Singh S,Singh TP,Yadav S

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Prmt5 plays major role in regulation of gene expression, RNA processing, cell growth and differentiation, signal transduction, germ cell development, etc., in mammals. Prmt5 is also related to cancer. Knowing the proteins interacting with Prmt5 is important to understand Prmt5's function in cells. Although t...

journal_title：Protein and peptide letters

authors： Shen H,Zhang X,Al Hafiz MA,Liang X,Yao Q,Guo M,Xu G,Zhong X,Zhou Q,Zhao H

更新日期：2020-01-01 00:00:00

abstract：:F(0)F(1)-ATPase is a rotary molecular motor. It is well known that the rotary torque is generated by ATP hydrolysis in F(1) but little is known about how it produces the proton-motive force (PMF) in F(0). Here a cross-linking approach was used to estimate the rotary torque produced by PMF. Three mutant E. coli strains...

journal_title：Protein and peptide letters

authors： Liu X,Cui Y,Chen C,Lai B,Yue J,Zhang Z

更新日期：2007-01-01 00:00:00

abstract：:Polymyositis is an inflammatory myopathy characterized by muscle invasion of T-cells penetrating the basal lamina and displacing the plasma membrane of normal muscle fibers. In order to understand the different adhesive mechanisms at the T-cell surface, Schubert randomly selected 19 proteins expressed at the T-cell su...

journal_title：Protein and peptide letters

authors： Li FZ,Gao F

更新日期：2012-08-01 00:00:00

abstract：:Nicotinamide adenine dinucleotide (NAD) plays an important role in cellular metabolism and acts as hydrideaccepting and hydride-donating coenzymes in energy production. Identification of NAD protein interacting sites can significantly aid in understanding the NAD dependent metabolism and pathways, and it could further...

journal_title：Protein and peptide letters

authors： Wang X,Wang CC,Zhang YQ,Mi G,Zhang J,Li ML

更新日期：2012-05-01 00:00:00

abstract：:The stability of Merrifield linker in Fmoc deprotection process was quantitatively investigated by establishing working curve of two major decomposition components from two resin bound dipeptide models. By sampling reaction solution and analyzing with RP-HPLC, decomposition rate was determined. The results indicated t...

journal_title：Protein and peptide letters

authors： Yang X,Lin H,Lu W,Wang D

更新日期：2013-02-01 00:00:00

abstract：:Oblique orientated alpha-helices are highly specialised protein structural elements that penetrate membranes at a shallow angle and are used to promote membrane destabilisation by a number of protein classes. Here, the use of extended hydrophobic moment methodology shows that the amphibian extrudates, aurein 1.2 and c...

journal_title：Protein and peptide letters

authors： Dennison SR,Harris F,Phoenix DA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Breast cancer demands safe adjuvant to overcome the side effects of standard drug tamoxifen. Diet derived bioactive compounds are reported to exhibit modulation of cancer growth leading to cell death. Chickpea is a protein rich edible legume with several bioactive compounds that includes lectin as well. Char...

journal_title：Protein and peptide letters

authors： Gupta N,Bisen PS,Bhagyawant SS

更新日期：2018-01-01 00:00:00

abstract：:A method for seed proteome analysis using MALDI-TOF mass spectrometry is described. The data were used to estimate the genetic diversity degree among twelve genotypes of pepper (Capsicum). The resulting spectra were converted into a binary matrix consisting of 23 protein data sets, and genetic similarity values were c...

journal_title：Protein and peptide letters

authors： de Pinho Pessoa Filho MA,Bloch Junior C,da Silva Filho DF,Galdino AS,da Cunha RM,Alves MA,Grangeiro TB

更新日期：2004-02-01 00:00:00

abstract：:PepX is a X-prolyl dipeptidyl aminopeptidase of S15 family that cleaves dipeptides from the N-terminus of polypeptides having a proline or alanine residue at the second position. Involved in bacterial nutrition and in peptide maturation, this serine exopeptidase, counterpart of the mammalian DDP-4, has been proposed t...

journal_title：Protein and peptide letters

authors： André J,Bach M,Xie J,Rigolet P

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:OPT3s are involved in the transport of Fe from xylem to phloem, in loading Fe into phloem, and in the transmission of shoot-to-root iron signaling. Yet, apart from Arabidopsis, little is known about these transporters'functions in other plant species. OBJECTIVE:OPT3 proteins of several plant species were ch...

journal_title：Protein and peptide letters

authors： Kurt F

更新日期：2020-06-25 00:00:00

abstract：:A recombinant human parathyroid hormone (rhPTH) fragment (Gly1-Gln26-rhPTH(1-34)) which contains two amino acids substitutions (Gly1 and Gln26) was acquired through Escherichia coli expression system using a soluble fusion protein strategy. The soluble fusion protein MBP-Gly1-Gln26-rhPTH(1-34) was harvested after puri...

journal_title：Protein and peptide letters

authors： Xu XC,Zhong SD,Kai F,Li LR,Liu C,Liu B,Bao JK

更新日期：2008-01-01 00:00:00

abstract：:Prediction of protein structure from its amino acid sequence is still a challenging problem. The complete physicochemical understanding of protein folding is essential for the accurate structure prediction. Knowledge of residue solvent accessibility gives useful insights into protein structure prediction and function ...

journal_title：Protein and peptide letters

authors： Pugalenthi G,Kandaswamy KK,Chou KC,Vivekanandan S,Kolatkar P

更新日期：2012-01-01 00:00:00

abstract：:Utilizing different computational methods; phosphorylation, O-GlcNAc modification and Yin Yang sites are predicted in HMGN-1. Prediction results suggest that interplay of phosphorylation and O-GlcNAc modification regulates binding and removal of HMGN-1 with the nucleosome and its translocation from nucleus to cytoplas...

journal_title：Protein and peptide letters

authors： Ahmad I,Khan TS,Hoessli DC,Walker-Nasir E,Kaleem A,Shakoori AR,Nasir-ud-Din

更新日期：2008-01-01 00:00:00

abstract：:A pivotal feature that underlies the development of neurodegeneration is the accumulation of protein aggregates. In response, eukaryotic cells have evolved sophisticated quality control mechanisms to identify, repair and/or eliminate the misfolded abnormal proteins. Chaperones identify any otherwise abnormal conformat...

journal_title：Protein and peptide letters

authors： Eldeeb MA,Ragheb MA,Esmaili M,Hussein F

更新日期：2020-01-01 00:00:00

abstract：:Influenza viruses cause a significant level of morbidity and mortality in the population every year. Their resistance to current anti-influenza drugs increases the difficulty of flu treatment. Thus, development of new anti-influenza drugs is necessary in regards of prevent the tragedy of influenza pandemic. The Polyme...

journal_title：Protein and peptide letters

authors： Lv HM,Guo XL,Gu RX,Wei DQ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Recently, the small molecule that inhibits the human copper-trafficking proteins Atox1 and CCS was reported, which suggested that small molecule has an effect on the copper regulation system in the cell. The copper chaperones CopC is regarded as a redox switch and possess barrel structure, thus the interacti...

journal_title：Protein and peptide letters

authors： Song Z,Liu J,Yuan W,Bai Z,Gao N

更新日期：2020-01-01 00:00:00

abstract：:A halophilic nucleoside diphosphate kinase from a moderate halophile, Halomonas sp. 593 (593NDK), was found to be resistant to heat treatment, as indicated by the high level of activity recovery after heating at high temperatures. This is due to reversibility of thermal unfolding, not the high melting temperature, of ...

journal_title：Protein and peptide letters

authors： Tokunaga H,Oda Y,Yonezawa Y,Arakawa T,Tokunaga M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:CsaA is among the few chaperones which are present in both bacteria and archaea, but absent in eukaryotes. There are no reports on interactome analysis of CsaA from archaea, till date. Identification of binding partners of CsaA might be helpful in understanding CsaA-associated processes in Picrophilus torrid...

journal_title：Protein and peptide letters

authors： Singhal N,Sharma A,Aswal M,Singh N,Kumar M,Goel M

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:Type VI Secretion System (T6SS) has been found in approximately onequarter of the gram-negative bacterial species, and its structural characteristics appear to slightly differ from species to species. The genes encoding T6SS are designated as type six secretion A-M (tssA-M). The expression of the tss gene cl...

journal_title：Protein and peptide letters

authors： Ok CK,Chang JH

更新日期：2019-01-01 00:00:00

abstract：:We here describe a new strategy for the delivery of oligonucleotides to cells that is based on the use of a short peptide containing three functional units: a membrane-penetrating segment, a DNA-binding domain and a cell-localization sequence. The designed vector binds strongly to oligonucleotides and has membrane-per...

journal_title：Protein and peptide letters

authors： Smith J,Guidry J,Wittung-Stafshede P

更新日期：2003-02-01 00:00:00