A 78-Year-Old Man With Repeated Dyspnea and Neutrophilia in Peripheral Blood and BAL.

abstract：BACKGROUND:Excessive daytime sleepiness (EDS) in individuals with OSA syndrome persisting despite good adherence to CPAP is a disabling condition. Pitolisant is a selective histamine H3-receptor antagonist with wake-promoting effects. RESEARCH QUESTION:Is pitolisant effective and safe for reducing daytime sleepiness i...

journal_title：Chest

authors： Pépin JL,Georgiev O,Tiholov R,Attali V,Verbraecken J,Buyse B,Partinen M,Fietze I,Belev G,Dokic D,Tamisier R,Lévy P,Lecomte I,Lecomte JM,Schwartz JC,Dauvilliers Y,HAROSA I Study Group.

更新日期：2020-10-26 00:00:00

abstract：OBJECTIVES:Tumor necrosis factor (TNF)-alpha is known to be a proinflammatory cytokine that has a pronounced negative inotropic effect and plays an important role in ischemic-reperfusion injury. METHODS:Twenty isolated rat hearts were randomly divided equally into two groups (heparin and non-heparin) and were perfused...

journal_title：Chest

authors： Pevni D,Frolkis I,Shapira I,Schwartz D,Yuhas Y,Schwartz IF,Chernichovski T,Uretzky G

更新日期：2005-09-01 00:00:00

abstract：:The mechanisms leading to rapid changes in arterial blood gas values soon after exercise ends have not been well established. To further study these phenomena, we exercised seven normal male volunteers to exhaustion on a cycle ergometer with a 25-W/min ramped protocol measuring arterial blood gas values, and breath-by...

journal_title：Chest

authors： O'Neill AV,Johnson DC

更新日期：1991-05-01 00:00:00

abstract：:Almitrine improves blood gas values in patients with COPD, primarily through better ventilation-perfusion matching. The improvement comes largely from a vasomotor effect of the drug. The vasomotor mechanism is unknown. We suspected that decreased distensibility of the large pulmonary arteries was one probable effect o...

journal_title：Chest

authors： Herve P,Musset D,Simonneau G,Wagner W Jr,Duroux P

更新日期：1989-09-01 00:00:00

abstract：:Etomidate is commonly used for the facilitation of endotracheal intubation. While etomidate possesses multiple qualities that are beneficial in hemodynamically unstable patients who require a sedative or amnestic, its potential to negatively impact corticosteroid production is well-documented. Given the frequency of r...

journal_title：Chest

authors： Jackson WL Jr

更新日期：2005-03-01 00:00:00

abstract：:Nearly all patients with pulmonary embolism (PE) have complete clinical and hemodynamic and at least near complete roentgenographic and angiographic resolution within four to six weeks of the acute event. To classify the syndrome of unresolved pulmonary embolism we reviewed our experience and that of the English liter...

journal_title：Chest

authors： Benotti JR,Ockene IS,Alpert JS,Dalen JE

更新日期：1983-12-01 00:00:00

abstract：:Pulmonary function studies were performed before and after one-time administration of an inhaled bronchodilator to ascertain the relative diagnostic value of using FVC, FEF25-75%, static lung volumes, Raw, and/or sGaw measurements, in addition to the FEV1, to assess the reversibility of chronic airways obstruction in ...

journal_title：Chest

authors： Berger R,Smith D

更新日期：1988-03-01 00:00:00

abstract：STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

journal_title：Chest

authors： Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：:In many patients with central airway obstruction due to extrinsic compression or malacia, insertion of tracheobronchial stents can provide effective and permanent relief. Of the various types of prostheses described, the silicone Dumon-Artemis stents (Medicore, Brussels, Belgium) are probably the most efficient. The u...

journal_title：Chest

authors： Noppen M,Dhondt E,Meysman M,Monsieur I,Gepts E,Vincken WG

更新日期：1994-08-01 00:00:00

abstract：:A case of amiodarone pulmonary toxicity (APT) occurring within days of the start of therapy and presenting with hemoptysis is reported. Both the very early onset and the presenting symptom are highly unusual in this entity. Implications in the diagnosis of APT are discussed. ...

journal_title：Chest

authors： Goldstein I,Topilsky M,Segev D,Isakov A,Heller I

更新日期：1997-05-01 00:00:00

abstract：:The results of previously published studies indicate that calcium channel blockers are capable of competitively inhibiting cytochrome P-450 activity in hepatic microsomes, the pathway of theophylline metabolism. In addition, case reports have suggested that theophylline serum concentrations change when a calcium chann...

journal_title：Chest

authors： Christopher MA,Harman E,Hendeles L

更新日期：1989-02-01 00:00:00

abstract：:Cocaine use is associated with adverse events in nearly every organ system. Cardiovascular complications include hemorrhagic and ischemic stroke, aortic dissection, cardiomyopathy, accelerated coronary artery disease, myocardial infarction, and sudden cardiac death. Syncope may be the presenting symptom in these condi...

journal_title：Chest

authors： Castro VJ,Nacht R

更新日期：2000-01-01 00:00:00

abstract：:Hyperlipemia in an acyanotic patient with diabetic ketoacidosis, alcoholism, and pancreatitis produced a falsely elevated concentration of methemoglobin (19 percent) and a lower-than-expected oxygen saturation measured with an automated spectrophotometer (IL-282 CO-Oximeter). In addition, there was a "normal" hemoglob...

journal_title：Chest

authors： Spurzem JR,Bonekat HW,Shigeoka JW

更新日期：1984-07-01 00:00:00

abstract：STUDY OBJECTIVES:The prevalence of gastroesophageal reflux disease (GERD) is higher in people with asthma than in control populations. Predisposing factors for GERD development may include asthma medications such as prednisone. The objective of this study was to determine whether prednisone alters GERD parameters in pe...

journal_title：Chest

authors： Lazenby JP,Guzzo MR,Harding SM,Patterson PE,Johnson LF,Bradley LA

更新日期：2002-02-01 00:00:00

abstract：:Endocardial involvement associated with disseminated histoplasmosis has been infrequently documented, especially among patients with prosthetic valves. The therapeutic approach to these patients is also not yet clearly defined. A 54-year-old man with prosthetic valve endocarditis due to histoplasmosis was successfully...

journal_title：Chest

authors： Kanawaty DS,Stalker MJ,Munt PW

更新日期：1991-01-01 00:00:00

abstract：:The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

journal_title：Chest

authors： Reents SB,Beck CA Jr

更新日期：1988-01-01 00:00:00

abstract：:Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classific...

journal_title：Chest

authors： Hopper RK,Abman SH,Ivy DD

更新日期：2016-07-01 00:00:00

abstract：:Inadequate tissue oxygenation may occur in critically ill patients with sepsis despite an apparently adequate O2 transport (QO2), and this may contribute to the development of an O2 debt and also to multiple organ failure. It has been shown that increasing QO2 by infusing a vasodilator may reveal this O2 debt in septi...

journal_title：Chest

authors： Pittet JF,Lacroix JS,Gunning K,Laverriere MC,Morel DR,Suter PM

更新日期：1990-12-01 00:00:00

abstract：INTRODUCTION:Over the last several years, there have been legal decisions and changes in medical directives concerning end-of-life decisions in Israel. METHODS:The data were compared to evaluate the changes in the frequency and types of forgoing of life-sustaining treatment (FLST) in patients who were admitted to the ...

journal_title：Chest

authors： Jakobson DJ,Eidelman LA,Worner TM,Oppenheim AE,Pizov R,Sprung CL

更新日期：2004-12-01 00:00:00

abstract：:Arterial blood samples from 75 patients were analyzed for PO2, PCO2, and pH at 0, 15, and 30 min. After the baseline analysis, 60 samples were kept in ice while 59 samples were left at room temperature. There was a statistically significant increase in the PO2 at 15 min and again at 30 min in both groups. There was a ...

journal_title：Chest

authors： Liss HP,Payne CP Jr

更新日期：1993-04-01 00:00:00

abstract：:To clarify the interrelation between interleukin-2 (IL-2) and soluble IL-2R receptor (sIL-2R), as products of T-cell activation in the bronchial tree of patients with bronchial asthma, we measured the concentration of IL-2, sIL-2R, and the cellular composition in bronchoalveolar lavage (BAL) fluid. We also measured ph...

journal_title：Chest

authors： Park CS,Lee SM,Chung SW,Uh S,Kim HT,Kim YH

更新日期：1994-08-01 00:00:00

abstract：:Right-sided chest lead ECGs (V3R to V6R) were recorded in 110 normal male subjects who were between the ages of 17 and 22 years old (mean, 17.9 years). The prevalence of the rS pattern decreased from V3R (89 percent) to V6R (37 percent). However, the opposite was the case for the rSr pattern (10 percent in V3R and 36 ...

journal_title：Chest

authors： Tan CC,Hiew TM,Chia BL

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Solitary pulmonary nodule (SPN) evaluation based on analyses of combined wash-in (WI) and washout (WO) values obtained by helical dynamic CT (HDCT) scanning is useful for malignant SPN characterization, because this method has higher specificity and accuracy than that based on analyses of WI values only. How...

journal_title：Chest

authors： Lee KS,Yi CA,Jeong SY,Jeong YJ,Kim S,Chung MJ,Kim HY,Kim YK,Lee KH

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) remains a major cause of morbidity following stroke. The optimal form of pharmacologic prophylaxis following stroke is unknown. METHODS:We identified randomized trials comparing unfractionated heparin (UFH) to low-molecular-weight heparin (LMWH) for VTE prevention in ischemic st...

journal_title：Chest

authors： Shorr AF,Jackson WL,Sherner JH,Moores LK

更新日期：2008-01-01 00:00:00

abstract：:Pulmonary Langerhans cell histiocytosis, also known as eosinophilic granuloma, is an uncommon interstitial lung disease. A solitary nodule, usually parenchymal, may rarely be the only manifestation of the disease. We describe a case of Langerhans cell histiocytosis presenting as an obstructing tracheal lesion in a 55-...

journal_title：Chest

authors： Fridlender ZG,Glazer M,Amir G,Berkman N

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...

journal_title：Chest

authors： Stenfors N

更新日期：2006-09-01 00:00:00

abstract：:The effect of broxaterol, a new beta 2-agonist, on respiratory muscle endurance and strength was studied in a double-blind, placebo-controlled, randomized crossover clinical trial in 16 patients with chronic obstructive pulmonary disease (COPD) with irreversible airway obstruction (FEV1 = 57.1 percent of predicted). O...

journal_title：Chest

authors： Nava S,Crotti P,Gurrieri G,Fracchia C,Rampulla C

更新日期：1992-01-01 00:00:00

abstract：:A new bronchoscopic-protected catheter brush (BPCB), designed to obtain uncontaminated bronchial secretions, was studied in vitro and in vivo. The device was composed of a standard biopsy brush, protected by a single catheter and occluded with an agar plug. Ejection of the plug was obtained neither by advancing the br...

journal_title：Chest

authors： Marquette CH,Ramon P,Courcol R,Wallaert B,Tonnel AB,Voisin C

更新日期：1988-04-01 00:00:00

abstract：:Persisting symptoms, consisting of palpitations, dizziness, or syncope, were found in 49 of 570 consecutively followed patients (8.6 percent) with permanent pacemakers (PM). Among 540 patients with ventricular PM, 19 had syncope and 24 dizziness; among 30 patients with dual-chamber PM, five had palpitations and one di...

journal_title：Chest

authors： Hoffman A,Jost M,Pfisterer M,Burkart F,Burckhardt D

更新日期：1984-02-01 00:00:00