Ultrastructural characterisation of macrophages (type A cells) in the synovial lining.

Abstract:

:The ultrastructural localisation of class II and macrophage antigens has been sought in the intimal layer of the human synovium. The cells described as type A in early morphological studies are shown to express both class II antigens and two markers of the macrophage/monocyte lineage of cells, OKM1 and MAB 24. The morphological type B cells were found to express none of these antigens. The findings are consistent with the idea that the synovial lining comprises two cell types, bone-marrow derived macrophages and mesenchymal fibroblasts.

journal_name

Rheumatol Int

authors

Mapp PI,Revell PA

doi

10.1007/BF00270456

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

171-6

issue

4

eissn

0172-8172

issn

1437-160X

journal_volume

8

pub_type

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