Abstract:
:The purpose of this study was to detect the frequency of inflammatory cervical spine changes and characteristic features such as resorption in rheumatoid arthritis (RA) with arthritis mutilans (AM) hand deformity. The series included 23 patients with AM hand deformity who fulfilled the 1987 American Rheumatism Association criteria for RA. Cervical spine radiographs were evaluated for subluxations, atlantoaxial impaction (AAI), and apophyseal joint ankylosis. Assessment of the severity of inflammatory changes in the cervical spine was based on former radiographic criteria for operation. Twenty patients (87%) showed subluxations, AAI, or apophyseal joint ankylosis in the cervical spine. Anterior atlantoaxial subluxation (aAAS) was observed in nine (39%), AAI in 13 (57%), and apophyseal joint ankylosis in 12 (52%). Six (26%) had been operated on the cervical spine. Patients with AM hand deformity evinced frequent and severe inflammatory cervical spine changes often requiring operation. Resorptive change (AAI) in the upper cervical spine and ankylosis of apophyseal joints were the most characteristic abnormalities in these patients.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Laiho K,Belt E,Kauppi Mdoi
10.1007/s002960100114subject
Has Abstractpub_date
2001-08-01 00:00:00pages
225-8issue
6eissn
0172-8172issn
1437-160Xjournal_volume
20pub_type
杂志文章abstract::Celiac disease (CD) is an autoimmune systemic disease characterized by not only gastrointestinal but also extraintestinal manifestations. The aim of our study was to do a serological screening for CD, by IgA endomysial antibodies (EmA), in patients with unexplained articular manifestations. Two hundred and eleven pati...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-013-2906-x
更新日期:2014-05-01 00:00:00
abstract::In a randomized multicenter, double-blind, double-dummy, parallel group study a comparison of the efficacy and safety of 1 microg alfacalcidol to 880 IU vitamin D plus calcium carbonate (1 g calcium) once daily per os was performed on 148 postmenopausal osteoporotic Caucasian patients with normal vitamin D serum level...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00296-005-0073-4
更新日期:2006-03-01 00:00:00
abstract::Sphingolipids are components of the plasma membrane whose metabolic manipulation is of interest as a potential therapeutic approach in a number of diseases. Sphingosine kinase 1 (SphK1), the major kinase that phosphorylates sphingosine to sphingosine-1-phosphate (S1P), was previously shown by our group and others to m...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2493-2
更新日期:2013-10-01 00:00:00
abstract::An abnormal immune response towards the Epstein-Barr virus (EBV) has been documented in patients with rheumatoid arthritis (RA). To investigate whether these findings are due to the transformation event caused by EBV, RA blood mononuclear cells and monocyte-enriched preparations were incubated with two different EBV s...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00271873
更新日期:1989-01-01 00:00:00
abstract::We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0988-2
更新日期:2010-04-01 00:00:00
abstract::To investigate the expression and effect of farnesoid X receptor (FXR) on systemic lupus erythematosus (SLE) liver dysfunction and indicate its hepatoprotective role and the immunomodulatory property. mRNA and protein levels of FXR were determined on the liver specimens of SLE patients with liver injury as well as MRL...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1874-2
更新日期:2012-06-01 00:00:00
abstract::Tuberculosis (TB) is an important preventable infection in patients with rheumatoid arthritis (RA). To determine the risk of TB in patients with RA by comparing with those with non-specific back pain (NSBP), and to identify the risk factors in the RA group. Medical data were retrieved from a centralized electronic dat...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04583-8
更新日期:2020-06-01 00:00:00
abstract::Heart rate variability (HRV) is a useful tool for the detection of sympathetic-parasympathetic balance in the autonomic nervous system. Autonomic nervous system involvement in patients with rheumatoid arthritis (RA) has rarely been studied and has shown conflicting results. Our purpose was to determine if HRV showed c...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0357-5
更新日期:2004-07-01 00:00:00
abstract::Osteopoikilosis, a form of osteosclerotic disorders, is a rare bone dysplasia with typical radiologic findings. The pathology, which sometimes requires attention in differential diagnosis due to its radiologic appearance, has been reported previously with other diseases. In this report, a case diagnosed with both reac...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0037-8
更新日期:2006-05-01 00:00:00
abstract::CD28 is one of the main activator receptors involved in systemic lupus erythematosus (SLE) pathogenesis, and its expression and serum levels are significantly higher in patients with SLE and other autoimmune diseases than in healthy controls (HC). However, it is unknown whether this increase is associated with specifi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1479-1
更新日期:2011-10-01 00:00:00
abstract::In patients suffering from ankylosing spondylitis (AS) HLA-B27 determination by means of the microlymphocytotoxicity test (MLCT) sometimes gives equivocal or false-negative results even though it has been performed with meticulous care. These failures of the test did not arise when the isolated mononuclear cells (MNC)...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00301265
更新日期:1993-01-01 00:00:00
abstract::Crystalglobulinemia is an extremely rare pathology that is associated in most cases with plasma cell dyscrasia, mainly multiple myeloma. In most cases, it may be the manifestation of incipient gammopathy or it manifests shortly after diagnosis. We report a patient with ischemic lesions of thrombotic origin in lower li...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-020-04620-6
更新日期:2020-08-01 00:00:00
abstract::The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report results of the cross-cultural adaptation and validation of the parent and patient v...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-018-3969-5
更新日期:2018-04-01 00:00:00
abstract::Sixty-six hospitalized patients with systemic lupus erythematosus (SLE) were enrolled into this study. The test for anti-mitochondrial antibodies (AMAs) was performed and biochemical parameters were determined. AMAs were detected in 15 of the 66 patients with SLE. Meanwhile, we compared enzymatic levels in AMA-positiv...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0034-y
更新日期:2006-06-01 00:00:00
abstract::Chondrocyte structure and function under the influence of two gold-containing therapeutic agents, aurothioglucose and triethylphosphine gold, were studied in a monolayer culture system for cultivating lapine articular chondrocytes. The functional parameters investigated were chondrocyte proliferation and the incorpora...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541144
更新日期:1983-01-01 00:00:00
abstract::The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with avai...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04762-7
更新日期:2021-01-02 00:00:00
abstract::The objective was to investigate the effect of activin A on matrix metalloproteinase 3 (MMP-3) production and to identify the role of activin A in chondroprotection. SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentration...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0350-5
更新日期:2007-09-01 00:00:00
abstract::This study aims to elucidate plasma oxidant/antioxidant status in patients with rheumatoid arthritis (RA). Fasting blood samples were obtained from 24 patients with RA and 20 control subjects. Antioxidant potential (AOP) value, nonenzymatic superoxide radical scavenger activity (NSSA), and malondialdehyde (MDA) levels...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960050097
更新日期:1999-01-01 00:00:00
abstract::The objectives of this study are to describe appropriateness and drug treatment of comorbidities in fibromyalgia (FM). Cross-sectional study of a group of patients. Number of drugs, indication, duration and appropriateness of prescriptions were evaluated. Patients were classified as: group 1, (FM/FM) previous FM diagn...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3568-2
更新日期:2016-12-01 00:00:00
abstract::We assess the usefulness of 99mTc-pertechnetate hand perfusion scintigraphy in patients with Raynaud's phenomenon (RP). The study population consisted of 18 patients with primary RP, 25 patients with secondary RP within systemic sclerosis (SSc), and ten healthy individuals. Gamma camera dynamic first-pass study during...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3584-2
更新日期:2016-12-01 00:00:00
abstract::The thiol status of patients with rheumatoid arthritis is significantly different from that of controls. Plasma thiol levels are lower, albumin thiol reactivity is altered and intracellular thiol levels measured after hemoglobin precipitation are increased. These variations correlate with other indices of disease seve...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541162
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVES:To identify recommendations on the diagnosis and management of rheumatoid arthritis (RA) supported by low recommendation grades, to study the causes of this low grading, and to propose solutions. METHODS:A group of six rheumatologists, with extensive experience in the development of systematic reviews, revi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04724-z
更新日期:2021-01-01 00:00:00
abstract::While carpal tunnel syndrome (CTS) is the most common entrapment neuropathy presented at rheumatologic consultation, its ulcerative variant is rarely described. We report of a case of severe bilateral medial nerve palsy, presented to us for diagnosis of chronic digital ulcers which had been suspected to be rheumatolog...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1229-4
更新日期:2011-05-01 00:00:00
abstract:KEY MESSAGES:No difference between both hands was observed for clinical and radiographical presentations in EHOA patients. A bilateral and symmetrical relationship was found between hand joints. HIGHLIGHTS:EHOA have symmetrical distribution and specific association in structural lesions. This study aims to analyse the...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04784-1
更新日期:2021-01-27 00:00:00
abstract::To translate and culturally adapt the Mayo Elbow Performance Score (MEPS), a widely used instrument for evaluating disability associated with elbow injuries, into Turkish (MEPS-T) and to determine psychometric properties of the translated version. The MEPS was translated into Turkish using published methodological gui...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3201-1
更新日期:2015-06-01 00:00:00
abstract::The aim of this study was to analyze the characteristics of patients with diffuse connective tissue diseases (CTDs) complicated by pneumomediastinum and identify the risk factors associated with increased mortality in these patients. Twenty-eight patients with CTD-associated pneumomediastinum, who were admitted to our...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3046-7
更新日期:2014-12-01 00:00:00
abstract::Addison's disease is an autoimmune process. However, Addison's disease associated with connective tissue diseases (CTD) is only occasionally reported. Here, we report six cases of Addison's disease secondary to a variety of CTD, which include systemic lupus erythematosus, Takayasu arteritis, systemic sclerosis, ankylo...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0749-7
更新日期:2009-04-01 00:00:00
abstract::The aim of this study was to evaluate whether cyclosporin A (CsA) influences the radiological disease progression in early rheumatoid arthritis (RA) patients in comparison with other disease-modifying drugs (DMARDs). A total of 103 early RA patients, without prior use of DMARDs, were randomized to receive CsA (3 mg/kg...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002960050113
更新日期:2000-01-01 00:00:00
abstract::The family name of author Francesco La Torre was incorrect in the published article. The correct family name should read as La Torre F. ...
journal_title:Rheumatology international
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00296-018-4042-0
更新日期:2018-07-01 00:00:00
abstract::Objective of the study is to investigate how compliance during the first year of methotrexate (MTX) treatment in rheumatoid arthritis (RA) is influenced by the patients' perception of the necessity for and concern about MTX, the patients' functional disability, and the dose of MTX. A total of 126 RA patients completed...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1160-8
更新日期:2010-09-01 00:00:00