Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy.

abstract：:In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Emodin is a naturally occurring anthraquinone which is ...

journal_title：Photochemistry and photobiology

authors： Rahimipour S,Bilkis I,Péron V,Gescheidt G,Barbosa F,Mazur Y,Koch Y,Weiner L,Fridkin M

更新日期：2001-08-01 00:00:00

abstract：:Light is a very important environmental factor that governs many cellular responses in organisms. As a consequence, organisms possess different kinds of light-sensing photoreceptors to regulate their physiological variables and adapt to a given habitat. The cryptochrome/photolyase family (CPF) includes photoreceptors ...

journal_title：Photochemistry and photobiology

authors： Kavakli IH,Baris I,Tardu M,Gül Ş,Öner H,Çal S,Bulut S,Yarparvar D,Berkel Ç,Ustaoğlu P,Aydın C

更新日期：2017-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

journal_title：Photochemistry and photobiology

authors： Kercher EM,Nath S,Rizvi I,Spring BQ

更新日期：2020-03-01 00:00:00

abstract：:The objective of the present study was to investigate the treatment of 9L gliosarcoma brain tumor in the rat with the combination of surgical resection and photodynamic therapy (PDT). Nude rats with intracranial 7-day-old 9L gliomas were randomly subjected to no treatment, PDT alone (Photofrin: 2 mg kg(-1), optical: 8...

journal_title：Photochemistry and photobiology

authors： Zhang X,Jiang F,Kalkanis SN,Yang H,Zhang Z,Katakowski M,Hong X,Zheng X,Chopp M

更新日期：2006-11-01 00:00:00

abstract：:Endogenous cellular chromophores absorb ultraviolet A radiation (UVA, 290-320 nm), the major UV component of terrestrial solar radiation, leading to the formation of reactive oxidizing species that initiate apoptosis, gene expression and mutagenesis. UVA-induced apoptosis of T helper cells is believed to underlie the ...

journal_title：Photochemistry and photobiology

authors： Zhuang S,Kochevar IE

更新日期：2003-07-01 00:00:00

abstract：:The quantum yield, phi ZE, for configurational photoisomerization (4Z,15Z----4Z,15E) of bilirubin bound non-covalently to human serum albumin was determined (at 23 +/- 2 degrees C) by laser excitation and chromatographic analysis of products. Values obtained for photoexcitation at 465 nm were about one-half those prev...

journal_title：Photochemistry and photobiology

authors： Agati G,Fusi F,Pratesi R,McDonagh AF

更新日期：1992-02-01 00:00:00

abstract：:A novel continuous-flow photocatalytic reactor was designed to decompose toluene by using porous nickel sheets that were coated with a Fe-doped TiO2 catalyst. While locating the UV lamp at the central axis, the catalyst sheets were located along the inner wall and positioned vertically with an equal space of 50 mm alo...

journal_title：Photochemistry and photobiology

authors： Dezhi S,Sheng C,Chung JS,Xiaodong D,Zhibin Z

更新日期：2005-03-01 00:00:00

abstract：:Dark-grown leaves of maize (Zea mays), wheat (Triticum aestivum), wild-type pea (Pisum sativum) and its light-independent photomorphogenesis mutant (lip1) have different proportions of protochlorophyllide (Pchlide) forms as revealed by low-temperature fluorescence emission spectra. Four discrete spectral forms of Pchl...

journal_title：Photochemistry and photobiology

authors： Myśliwa-Kurdziel B,Amirjani MR,Strzałka K,Sundqvist C

更新日期：2003-08-01 00:00:00

abstract：:Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone with a structural resemblance to tryptophan. Its fluorescence is solvent dependent and strongly quenched in the presence of oxygen. Fluorescence quenching in aqueous and organic solutions have been studied in the presence of different quenchers....

journal_title：Photochemistry and photobiology

authors： Rath MC,Mahal HS,Mukherjee T

更新日期：1999-03-01 00:00:00

abstract：:The incidence and prevalence of inflammatory bowel disease (IBD) are increasing worldwide. Some ecological studies show increasing incidence with increasing latitude. Ambient ultraviolet radiation varies inversely with latitude, and sun exposure of the skin is a major source of vitamin D. Vitamin D deficiency is commo...

journal_title：Photochemistry and photobiology

authors： Holmes EA,Rodney Harris RM,Lucas RM

更新日期：2019-01-01 00:00:00

abstract：:The psaI and psaL genes were characterized from the cyanobacterium Synechococcus sp. strain PCC 7002. The gene organization was different from that reported for other cyanobacteria with psaI occurring upstream and being divergently transcribed from the psaL gene. Mutants lacking PsaI or PsaL were generated by interpos...

journal_title：Photochemistry and photobiology

authors： Schluchter WM,Shen G,Zhao J,Bryant DA

更新日期：1996-07-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:Direct irradiation of estrone aryl and methyl sulfonates in different organic solvents under nitrogen atmosphere was investigated under steady-state conditions. The estrone derivatives reacted efficiently through the photo-Fries rearrangement reaction involving [1;3]-sulfonyl migration providing the ortho-sulfonyl est...

journal_title：Photochemistry and photobiology

authors： Quindt MI,Gola GF,Ramirez JA,Bonesi SM

更新日期：2021-01-01 00:00:00

abstract：:The seminal discovery by James Cleaver of defective DNA repair in xeroderma pigmentosum (XP) opened up an ever-expanding field of DNA repair-related disorders. In addition, it put XP on the map and has led to improved diagnosis, care and management of affected patients. In the United Kingdom, we recently established a...

journal_title：Photochemistry and photobiology

authors： Lehmann AR

更新日期：2015-03-01 00:00:00

abstract：:We describe here the development of monoclonal antibodies to the hapten tryptophan-riboflavin, generated by irradiation of a solution of bovine serum albumin in the presence of riboflavin. The specificity of the three obtained monoclonal antibodies, named 1E6, 5H5, 5A8 all belonging to the IgG1 isotype, was assessed b...

journal_title：Photochemistry and photobiology

authors： Diaz M,Becker MI,De Ioannes AE,Silva E

更新日期：1996-06-01 00:00:00

abstract：:The proteins induced by heat and other stressors, called heat shock proteins (HSP) or stress proteins, are considered to play a general role in protection from cellular injury. Exposure to UVA (320-400 nm) following application of 8-methoxypsoralen (8-MOP), termed PUVA is commonly used in the field of dermatology. In ...

journal_title：Photochemistry and photobiology

authors： Muramatsu T,Yamashina Y,Tada H,Kobayashi N,Yamaji M,Ohno H,Shirai T,Takahashi A,Ohnishi T

更新日期：1993-12-01 00:00:00

abstract：:We report the synthesis of twelve indole derivatives bearing nitro or amide groups via Fischer indole methodology followed by reduction/acetylation and amidation reactions. After thorough characterization, these indoles were subjected to a number of studies in order to evaluate their bioactive potential as photosynthe...

journal_title：Photochemistry and photobiology

authors： de Souza JM,Fazolo BR,Lacerda JWF,Moura MS,Dos Santos ACR,de Vasconcelos LG,de Sousa Junior PT,Dall'Oglio EL,Ali A,Sampaio OM,Vieira LCC

更新日期：2020-11-01 00:00:00

abstract：:A targeting strategy based on the selective enzyme-mediated activation of polymeric photosensitizer prodrugs (PPP) within pathological tissue has led to the development of agents with the dual ability to detect and treat cancer. Herein, a detailed study of a simple model system for these prodrugs is described. We prep...

journal_title：Photochemistry and photobiology

authors： Campo MA,Gabriel D,Kucera P,Gurny R,Lange N

更新日期：2007-07-01 00:00:00

abstract：:Detergent solubilized bacteriorhodopsin (BR) proteins which contain alterations made by site-directed mutagenesis (Asp-96----Asn, D96N; Asp-85----Asn, D85N; and Arg-82----Gln, R82Q) have been studied with resonance Raman spectroscopy. Raman spectra of the light-adapted (BRLA) and M species in D96N are identical to tho...

journal_title：Photochemistry and photobiology

authors： Lin SW,Fodor SP,Miercke LJ,Shand RF,Betlach MC,Stroud RM,Mathies RA

更新日期：1991-03-01 00:00:00

abstract：:In this issue, we offer a symposium-in-print that is focused on several new advancements in fundamental research related to the family of GFP (green fluorescent protein)-like proteins. A few applied aspects are also included to illustrate the impact this amazing set of colored proteins has made on our understanding of...

journal_title：Photochemistry and photobiology

authors： Wachter RM

更新日期：2006-03-01 00:00:00

abstract：:Here, 10 guidelines are presented for a standardized definition of type I and type II photosensitized oxidation reactions. Because of varied notions of reactions mediated by photosensitizers, a checklist of recommendations is provided for their definitions. Type I and type II photoreactions are oxygen-dependent and in...

journal_title：Photochemistry and photobiology

authors： Baptista MS,Cadet J,Di Mascio P,Ghogare AA,Greer A,Hamblin MR,Lorente C,Nunez SC,Ribeiro MS,Thomas AH,Vignoni M,Yoshimura TM

更新日期：2017-07-01 00:00:00

abstract：:Four chemical preservatives commonly used in ophthalmic solutions were tested for their toxic and mutagenic potential in mouse lymphoma cells with and without exposure of the cells to ultraviolet A (UVA) radiation. The preservatives tested were benzalkonium chloride (BAK), chlorhexidine, thimerosal and ethylenediamine...

journal_title：Photochemistry and photobiology

authors： Withrow TJ,Brown NT,Hitchins VM,Strickland AG

更新日期：1989-09-01 00:00:00

abstract：:Low-level light therapy has been used in health care as a therapeutic strategy for different diseases. However, its effects on cancer are controversial. This work evaluated the effects of three energies on breast cancer-bearing mice after a single red light-emitting diode (LED) irradiation. 4T1 cells were inoculated i...

journal_title：Photochemistry and photobiology

authors： Pereira ST,Silva CR,Nuñez SC,Ribeiro MS

更新日期：2020-10-03 00:00:00

abstract：:Leaf discs, enclosed in a photoacoustic (PA) chamber, generate two types of PA gas-uptake signals under certain conditions. Type I is manifested by a severe signal decrease that develops slowly under very low-light intensity and often reaches negative values. It is partially reversed by low-intensity far-red light. Ty...

journal_title：Photochemistry and photobiology

authors： Malkin S,Havaux M

更新日期：2001-10-01 00:00:00

abstract：:Albino hairless mice (Skh: HR-1) exposed chronically to sub-erythemal doses of UV radiation display physical, visible and histological alterations. Using narrow bandwidth radiation covering the UV radiation spectrum from 280-380 nm, the wavelength dependence of these alterations was determined. The wavelength dependen...

journal_title：Photochemistry and photobiology

authors： Bissett DL,Hannon DP,Orr TV

更新日期：1989-12-01 00:00:00

abstract：:Photobiomodulation therapy (PBMT) has anti-inflammatory, analgesic and regenerative properties. This systematic review aimed to critically appraise the published data of in vivo human randomized clinical trials (RCTs), and present a comprehensive overview of the efficacy of PBMT, as an adjunct to the nonsurgical perio...

journal_title：Photochemistry and photobiology

authors： Dalvi S,Benedicenti S,Hanna R

更新日期：2020-10-24 00:00:00

abstract：:Phototropin is a blue light-activated photoreceptor that plays a dominant role in the phototropism of plants. The protein contains two subunits that bind flavin mononucleotide (FMN), which are responsible for the initial steps of the light-induced reaction. It has been proposed that the photoexcited flavin molecule ad...

journal_title：Photochemistry and photobiology

authors： Neiss C,Saalfrank P

更新日期：2003-01-01 00:00:00

abstract：:A series of luminescent ion exchanged zeolite are synthesized by introducing various ions into NaY zeolite. Monometal ion (Eu(3+), Tb(3+), Ce(3+), Y(3+), Zn(2+), Cd(2+), Cu(2+)) exchanged zeolite, rare-earth ion (Eu(3+), Tb(3+), Ce(3+)) exchanged zeolite modified with Y(3+) and rare-earth ion (Eu(3+), Tb(3+), Ce(3+)) ...

journal_title：Photochemistry and photobiology

authors： Duan TW,Yan B

更新日期：2014-05-01 00:00:00

abstract：:We analyzed the photoinactivation of the membrane functions of bacteria and erythrocytes induced by xanthene dyes. The dyes tested were rose bengal, phloxine B, erythrosine B and eosin B. These dyes induced the leakage of K(+) from Staphylococcus aureus cells within minutes of photoirradiation, in the order of rose be...

journal_title：Photochemistry and photobiology

authors： Kato H,Komagoe K,Nakanishi Y,Inoue T,Katsu T

更新日期：2012-03-01 00:00:00

abstract：:The UVA and UVB components of sunlight can produce three classes of bipyrimidine DNA photolesions [cyclobutane pyrimidine dimers (CPDs), pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) and related Dewar valence isomers (DewarPPs)]. The UVA/UVB ratio of sunlight is high in winter and low in summer in the Northern He...

journal_title：Photochemistry and photobiology

authors： Nishimura K,Ikehata H,Douki T,Cadet J,Sugiura S,Mori T

更新日期：2020-12-03 00:00:00