Abstract：
:Vitiligo, an acquired disease of depigmentation, affects millions worldwide. The psychosocial and health-related quality of life (HRQL) impact of the disease varies based on several parameters, including country of origin, skin type, gender, age, marital status, and involved body site. Many instruments, both dermatology specific and dermatology nonspecific, have been used to measure HRQL. Assessing HRQL in vitiligo is an important part of disease management.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Bhandarkar SS,Kundu RVdoi
10.1016/j.det.2011.11.013subject
Has Abstractpub_date
2012-04-01 00:00:00pages
255-68, viiiissue
2eissn
0733-8635issn
1558-0520pii
S0733-8635(11)00210-5journal_volume
30pub_type
杂志文章,评审abstract：:Cutaneous T-cell lymphoma is a malignancy of skin-homing T cells. This unique population of lymphocytes requires alternative therapies to those used in nodal lymphomas. Although phototherapy and nitrogen mustard have been standard treatments for decades, newer therapies have been arriving with increased frequency. Mor...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.03.010
更新日期：2010-07-01 00:00:00
abstract：:Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(02)00082-7
更新日期：2003-01-01 00:00:00
abstract：:Although trichoscopy has only recently been introduced in the assessment of hair and scalp disorders, it is already considered an essential diagnostic tool by many experts in the field. This article discusses topics that are often a source of doubt among clinicians, and tips that may help dermatologists better perform...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.05.008
更新日期：2018-10-01 00:00:00
abstract：:There has been a resurgence over the past decade of microlipoinjection. Adipose tissue has proved to be a safe and effective filler substance for subcutaneous defects. More recently, lipocytic dermal augmentation, or autologous collagen, has been used to correct dermal defects. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1995-04-01 00:00:00
abstract：:Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.03.015
更新日期：2011-07-01 00:00:00
abstract：:A hypothesis is proposed for the etiopathogenesis of some cases of Hodgkin's disease, Sezary's syndrome, and related disorders that compose the cutaneous T-cell lymphoma group. This new model, termed the thymus bypass model, is discussed in detail in this article. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1994-04-01 00:00:00
abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.03.003
更新日期：2004-07-01 00:00:00
abstract：:Atopic dermatitis is associated with significant patient burden, with impacts from symptoms and visible physical manifestations of the disease. Consequences include detrimental effects on quality of life (QoL), sleep, self-esteem, interpersonal relationships, participation in leisure and sports, and attendance or perf...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2017.02.004
更新日期：2017-07-01 00:00:00
abstract：:There are numerous cutaneous findings associated with liver diseases. Although most of these changes are nonspecific and therefore are of limited value in the actual diagnosis of hepatic disease, recognition of the association may be useful for diagnosis and for monitoring the patient's response to treatment. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Vasculitis may be defined as damage to blood vessels induced by pathologic processes, resulting in compromise of function of the organ in which the blood vessels reside. A large number of syndromes and disease processes exist in which vasculitis plays a key role. Selected vasculitic syndromes of special interest to de...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1990-10-01 00:00:00
abstract：:Pemphigus vulgaris, which has multiple clinical variants, is an autoimmune blistering disorder of skin and mucous membranes, usually affecting the elderly, with a strong immunogenetic link. Immunologic studies of this disease have been productive in defining the pathophysiology of blister formation and the characteris...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-07-01 00:00:00
abstract：:Many lesions that appear in the oral cavity manifest as a nodule or swelling. A particular lesion may have the clinical characteristics of several entities, and a differential diagnosis should be generated, with a final diagnosis reached by microscopic examination. This article discusses and shows the clinical feature...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70362-4
更新日期：1996-04-01 00:00:00
abstract：:There is a spectrum of melanocytic tumors from benign to malignant. The goal of the dermatologist is to identify and remove early melanomas because doing so can be lifesaving. At the same time, it is inappropriate to randomly remove benign nevi. Dermatoscopy is an additional tool that can be used to help discriminate ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70269-2
更新日期：2001-04-01 00:00:00
abstract：:The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radi...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.06.004
更新日期：2007-10-01 00:00:00
abstract：:It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha. Current immunosuppressive systemic treatments may be effective in controlling psoriasis to a certain degree but have significant dr...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2003.12.002
更新日期：2004-10-01 00:00:00
abstract：:Human papillomavirus infections of the skin and anogenital tract are common. The association of these viruses with neoplasia, particularly of the anogenital tract, has stimulated efforts to devise practical methods of detection and typing of HPV. Although experimental diagnostic tests are available, they are, for the ...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:Granuloma formation is usually regarded as a means of defending the host from persistent irritants of either exogenous or endogenous origin. Noninfectious granulomatous disorders of the skin encompass a challenging group of diseases owing to their clinical and histologic overlap. Drug reactions characterized by a gran...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2015.03.015
更新日期：2015-07-01 00:00:00
abstract：:Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1988-04-01 00:00:00
abstract：:Advances in laser technology now permit the physician to provide an effective form of treatment for a large variety of cutaneous disorders for which no previous therapy or only poor forms of therapy previously existed. Additional refinements in both laser instruments and treatment techniques are certain to have a prof...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Psoriasis vulgaris is a chronic inflammatory skin disease that results from the complex interplay between keratinocytes, dendritic cells, and T cells. Keratinocytes trigger innate and adaptive immune responses. Dermal myeloid dendritic cells regulate T cell activation and production of cytokines and chemokines that am...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2014.09.002
更新日期：2015-01-01 00:00:00
abstract：:Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the e...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.05.008
更新日期：2019-10-01 00:00:00
abstract：:The Israeli population is characterized by unique demographic features including high genetic homogeneity within many closed communities. As a consequence the molecular epidemiology of epidermolysis bullosa differs markedly in this country and surrounding areas from that reported in the Western world. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.02.019
更新日期：2010-04-01 00:00:00
abstract：:The diagnosis of lymphoma currently relies on a combination of clinical, routine histopathologic, and immunohistochemical studies, sometimes supplemented by other special techniques such as flow cytometry, DNA analysis, and gene rearrangement study. This review considers the practical diagnosis of cutaneous lymphoma, ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Cutaneous B-cell lymphomas represent a heterogeneous group of entities which show variation in histology, immunophenotype, and in prognosis. In the current review the morphologic spectrum of cutaneous B-cell lymphomas comprising primary and secondary cutaneous B-cell lymphomas is discussed according to the REAL classi...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70109-1
更新日期：1999-07-01 00:00:00
abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.01.012
更新日期：2007-04-01 00:00:00
abstract：:The author reviews published papers on human hair growth in nude mice. There is evidence from various sources indicating that grafting of human scalp onto nude mice does not modify significantly morphogenesis, hair follicle structure and function, and composition of the newly grown hair fiber. On the basis of personal...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70388-0
更新日期：1996-10-01 00:00:00
abstract：:To remain experts in skin care and treatment, every dermatologist must be aware of the evolving role of soft tissue fillers in dermatology. Patients with facial scarring, lipodystrophy, contour abnormalities, and age- and sun-induced rhytids can be successfully treated. A literature review, industry recommendations, a...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.09.009
更新日期：2005-04-01 00:00:00
abstract：:In this article, vulvar anatomy and histology are reviewed, and nonneoplastic and neoplastic epithelial disorders are presented. Included are lichen sclerosus, squamous cell hyperplasia, vulvar intraepithelial neoplasia, vulvar Paget's disease, and squamous cell carcinoma. Current terminology, tumor measurements, and ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：:Pediatric dermatologic disease that have specific therapies and/or specific prophylactic measures are reviewed. Herpes simplex virus and varicella-zoster virus infections, human papillomavirus infections, and molluscum contagiosum infections are discussed with special emphasis on recent advances of therapy and prophyl...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70251-5
更新日期：1998-07-01 00:00:00
abstract：:The recent progress made in understanding the normal biology and biochemistry of the extracellular matrix of human skin has allowed us to identify several different levels at which errors could be introduced into the structure and metabolism of collagen or elastin, the two major fibrillar components of the dermis. Cur...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
