Pemphigus vulgaris and vegetans.

abstract：:The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...

journal_title：Dermatologic clinics

authors： Solomon AR Jr

更新日期：1985-01-01 00:00:00

abstract：:The recent progress made in understanding the normal biology and biochemistry of the extracellular matrix of human skin has allowed us to identify several different levels at which errors could be introduced into the structure and metabolism of collagen or elastin, the two major fibrillar components of the dermis. Cur...

journal_title：Dermatologic clinics

authors： Uitto J,Shamban A

更新日期：1987-01-01 00:00:00

abstract：:Rituximab is a chimeric, murine-human, monoclonal antibody against the CD20 antigen of B lymphocytes. It has been used off-label to treat and manage autoimmune and dermatologic diseases as an alternative or adjuvant therapy to systemic treatments. Due to cost, potential complications, and lack of data rituximab is use...

journal_title：Dermatologic clinics

authors： Daniel BS,Murrell DF,Joly P

更新日期：2011-10-01 00:00:00

abstract：:Surgery for skin cancer is a major part of clinical dermatology, and the largest single component of dermatologic surgery practice. In general, residency training in dermatology provides comprehensive training in the theory and practice of skin cancer surgery. Practicing dermatologists are similarly expert in this are...

journal_title：Dermatologic clinics

authors： Alam M,Waldman A,Maher IA

更新日期：2016-07-01 00:00:00

abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...

journal_title：Dermatologic clinics

authors： Bouzari N,Olbricht S

更新日期：2011-04-01 00:00:00

abstract：:This article provides a detailed review of the vascular manifestations affecting the skin in relationship to internal malignancies. Vascular abnormalities heralding internal malignancies can be divided into three main categories, consisting of disorders related to vascular dilatation (flushing, palmar erythema, and te...

journal_title：Dermatologic clinics

authors： El Tal AK,Tannous Z

更新日期：2008-01-01 00:00:00

abstract：:The clinical diagnosis of malignant melanoma requires the following: an acceptance of the concept of "in situ" malignancy, both clinically and histologically; a high index of suspicion concerning any pigmented lesion; recalling the mnemonic "remember your A,B,C,D's"; and a knowledge of the clinical simulators of malig...

journal_title：Dermatologic clinics

authors： Friedman RJ,Rigel DS

更新日期：1985-04-01 00:00:00

abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...

journal_title：Dermatologic clinics

authors： Salvaggio MR,Baddley JW

更新日期：2004-07-01 00:00:00

abstract：:Contact dermatitis is the most common occupational skin disorder, responsible for up to 30% of all cases of occupational disease in industrialized nations. Epidemiologic data suggest that contact dermatitis accounts for 90% to 95% of all cases of occupational skin disease, imposing considerable social and economic imp...

journal_title：Dermatologic clinics

authors： Clark SC,Zirwas MJ

更新日期：2009-07-01 00:00:00

abstract：:Bullous disease in children can be confusing clinically and challenging to mange. Five groups of autoimmune bullous disease are discussed with emphasis on unique features in children. Pemphigus (vulgaris, foliaceus, neonatal), pemphigoid (bullous and cicatricial), dermatitis herpetiformis, linear IgA dermatosis, and e...

journal_title：Dermatologic clinics

authors： Rabinowitz LG,Esterly NB

更新日期：1993-07-01 00:00:00

abstract：:Diaper dermatitis is a term used to encompass a wide range of inflammatory processes that occur in the area covered by the diaper. The term "diaper dermatitis" is thus simply a description of the location of a rash. Numerous factors can be involved in the pathogenesis of dermatitis in the diaper area. These factors, i...

journal_title：Dermatologic clinics

authors： Leyden JJ

更新日期：1986-01-01 00:00:00

abstract：:The leishmaniases are a group of zoonotic infections caused by protozoan parasites of the genus Leishmania. These infections produce a variety of different clinical diseases depending on the virulence or tropism of the parasite and differential host immune responses. Newly recognized clinical presentations, such as vi...

journal_title：Dermatologic clinics

authors： Magill AJ

更新日期：1995-07-01 00:00:00

abstract：:Normal and malignant pigment cells are known targets for many hormones. Besides alpha-melanocyte-stimulating hormone and the steroidal hormones estrogen, testosterone, and glucocorticoids, factors produced by other epidermal cells can affect melanization and proliferation of pigment cells. Among those factors are the ...

journal_title：Dermatologic clinics

authors： Abdel-Malek ZA

更新日期：1988-04-01 00:00:00

abstract：:I would like to stress that there seem to be three subpopulations of neural crest-derived melanocytes in the body that can be functionally and morphologically distinguished: the cutaneous melanocytes, which continuously synthesize small melanosomes to be transferred to keratinocytes; the uveal melanocytes, which synth...

journal_title：Dermatologic clinics

authors： Boissy RE

更新日期：1988-04-01 00:00:00

abstract：:Cosmeceuticals are topically applied products that are more than merely cosmetic, yet are not true drugs that have undergone rigorous placebo controlled studies for safety and efficacy. There are many review articles that outline the theoretical biologic and clinical actions of these cosmeceuticals and their various i...

journal_title：Dermatologic clinics

authors： Reszko AE,Berson D,Lupo MP

更新日期：2009-10-01 00:00:00

abstract：:Stress is an abnormal or extreme adjustment in the physiology of an animal to cope with adverse effects of its environment and management. The adverse effect is designated the stressor. In this article, the authors try to focus on the main types of host factors that can influence stress (genetics, perception) and on t...

journal_title：Dermatologic clinics

authors： Panconesi E,Hautmann G

更新日期：1996-07-01 00:00:00

abstract：:Skin cancer is reaching epidemic levels in the United States. Recent advances in the understanding of the pathophysiology of melanoma have allowed improved risk stratification in the revised American Joint Committee on Cancer (AJCC) criteria, new tests to capture patients at higher risk than their stage may indicate, ...

journal_title：Dermatologic clinics

authors： Tracey EH,Vij A

更新日期：2019-01-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic, inflammatory, scarring condition involving the intertriginous skin of the axillary, inguinal, inframammary, genital, and perineal areas of the body. It is also referred to as acne inversa and Verneuil disease. Follicular occlusion is the primary event in HS. It is now accept...

journal_title：Dermatologic clinics

authors： Danby FW,Margesson LJ

更新日期：2010-10-01 00:00:00

abstract：:Primary cutaneous lymphomas comprise a prognostically heterogeneous group of lymphocytic skin neoplasms, which display a broad spectrum of clinical, histologic, immunophenotypic, and genetic features. The histopathological examination plays an essential role and is often the starting point in the diagnostic workup of ...

journal_title：Dermatologic clinics

authors： Kempf W,Mitteldorf C

更新日期：2015-10-01 00:00:00

abstract：:The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within ...

journal_title：Dermatologic clinics

authors： Wilson DC,King LE Jr

更新日期：1990-04-01 00:00:00

abstract：:Human papillomavirus infections of the skin and anogenital tract are common. The association of these viruses with neoplasia, particularly of the anogenital tract, has stimulated efforts to devise practical methods of detection and typing of HPV. Although experimental diagnostic tests are available, they are, for the ...

journal_title：Dermatologic clinics

authors： Lancaster WD,Jenson AB

更新日期：1991-04-01 00:00:00

abstract：:Improved therapy for CTCL will depend on a better understanding of the pathogenesis of this disease at a molecular level. It is clear that the T cells in MF and CTCL do not undergo normal programmed cell death and have prolonged lifespans. Skin flora or other antigens may stimulate the initial proliferation, offering ...

journal_title：Dermatologic clinics

authors： Duvic M,Cather JC

更新日期：2000-01-01 00:00:00

abstract：:Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...

journal_title：Dermatologic clinics

authors： Chen TM,George S,Woodruff CA,Hsu S

更新日期：2002-04-01 00:00:00

abstract：:Autoinflammatory diseases (AIDs) are characterized by recurrent episodes of systemic and organ-specific inflammation. Many of these diseases share fever as a common presenting feature. Physicians need to consider AIDs in children with recurrent, unexplained fevers, when infectious and malignant causes have been discar...

journal_title：Dermatologic clinics

authors： Hausmann JS,Dedeoglu F

更新日期：2013-07-01 00:00:00

abstract：:There is a spectrum of melanocytic tumors from benign to malignant. The goal of the dermatologist is to identify and remove early melanomas because doing so can be lifesaving. At the same time, it is inappropriate to randomly remove benign nevi. Dermatoscopy is an additional tool that can be used to help discriminate ...

journal_title：Dermatologic clinics

authors： Grichnik JM

更新日期：2001-04-01 00:00:00

abstract：:The general goals of medical management of vitiligo are to repigment vitiliginous areas of skin and to stabilize the progression of depigmentation. However, for some patients with vitiligo affecting extensive body surface areas who are unresponsive to repigmentation therapies, depigmentation of the remaining normal sk...

journal_title：Dermatologic clinics

authors： Grimes PE,Nashawati R

更新日期：2017-04-01 00:00:00

abstract：:There is a dearth of information on psoriasis in the tropics. Psoriasis occurs more frequently in northern geographic regions than in tropical climates. Its prevalence varies not only within the ethnic groups of a country but from country to country. A review of published studies on the natural history of psoriasis in...

journal_title：Dermatologic clinics

authors： Farber EM,Nall L

更新日期：1994-10-01 00:00:00

abstract：:Liposuction is the most popular cosmetic surgical procedure performed in men. Aside from traditional liposuction using the tumescent technique, several energy-assisted liposuction technologies have emerged and been proven safe and particularly beneficial for the male patient demographic. The differences in fat distrib...

journal_title：Dermatologic clinics

authors： Karcher C

更新日期：2018-01-01 00:00:00

abstract：:Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...

journal_title：Dermatologic clinics

authors： Silverstein D,Mariwalla K

更新日期：2012-07-01 00:00:00

abstract：:Sensitive skin is a complex problem with genetic, individual, environmental, occupational, and ethnic implications. Further work is needed to rank irritants and irritant reactions to classify sensitive skin on the basis of standard models. The development of topical products designed for sensitive and ethnic skin may ...

journal_title：Dermatologic clinics

authors： Berardesca E,Maibach HI

更新日期：1991-01-01 00:00:00