Abstract：
:The only spiders of real medical importance to humans in the United States are the Loxosceles and Latrodectus species, primarily the brown recluse and the black window, respectively. These spiders bite humans only when trapped or crushed against the skin. Severe brown recluse spider bites produce dermonecrosis within 72-96 hours, which should be treated with rest, ice compresses, antibiotics, dapsone, and surgery delayed for several weeks. Using systemic corticosteroids may be helpful in treating the much rarer systemic loxoscelism, which has minimal skin changes but produces massive hemolysis. Black widow bites do not produce marked skin changes but primarily produce muscle cramping, pain, and other neuromuscular-related symptoms. Though a specific antivenin for black widow bites is available, pain control, muscle relaxants, and calcium gluconate are generally adequate treatment. Many other spiders inflict painful bites, but arachnids do not medically deserve the bad reputation that they generally have with the public.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Wilson DC,King LE Jrsubject
Has Abstractpub_date
1990-04-01 00:00:00pages
277-86issue
2eissn
0733-8635issn
1558-0520journal_volume
8pub_type
杂志文章,评审abstract：:Nail psoriasis, melanonychia striata, and onychomycosis are relatively common nail disorders that have generated much research into their pathophysiology and treatment. The authors hope this discussion of the recent therapeutic developments for treating these disorders will not only inform but will also inspire furthe...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70145-5
更新日期：2000-01-01 00:00:00
abstract：:Hepatic itch remains among the most agonizing symptoms for affected patients and a major clinical challenge for physicians. Pruritus may occur in almost all liver diseases, particularly those with cholestatic features. Hepatic itch arises irrespective of the severity of the underlying liver disease or extent of choles...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2018.02.008
更新日期：2018-07-01 00:00:00
abstract：:Extramammary Paget disease is an intraepidermal adenocarcinoma, most often limited to the epidermis, with typical cases affecting genital skin. When limited to the epidermis, primary extramammary Paget disease is not life-threatening, but invasive disease may portend a poor prognosis. Surgical excision remains the mai...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.02.002
更新日期：2019-07-01 00:00:00
abstract：:Pharmaceutical manufacturing is one of the most financially lucrative industries in America due, in part, to massive marketing and advertising. The content of many symposia and medical journals as well as physician prescribing decisions seems to be influenced by the promotional efforts of pharmaceutical companies. In ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.05.006
更新日期：2008-10-01 00:00:00
abstract：:The leishmaniases are a group of zoonotic infections caused by protozoan parasites of the genus Leishmania. These infections produce a variety of different clinical diseases depending on the virulence or tropism of the parasite and differential host immune responses. Newly recognized clinical presentations, such as vi...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：:In part because of the increased public awareness regarding skin cancer, patients are presenting to their physician with thinner melanomas. Many lesions are now found in the in situ phase. The vast majority of melanomas referred to or diagnosed in the Skin Oncology Program at Boston University are less than 2 mm in th...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：:We have limited the scope of this article to those disorders that have already been successfully diagnosed or excluded in utero. We currently have the potential to diagnose a number of others for which the opportunity has not yet arisen. If a biochemical, morphologic, chromosomal, or DNA alteration is known for a spec...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
abstract：:The Armed Forces Institute of Pathology (AFIP) is well known for providing expert pathology in many specialties and educational courses for civilian and military personnel. Some of the departments at the AFIP have also developed expertise in various advanced laboratory techniques for diagnosis and research that are ap...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70074-7
更新日期：1999-01-01 00:00:00
abstract：:Melanocytic nevi represent benign clonal proliferations of the melanocytes in the skin that usually remain stable in size and behavior or disappear during life. Infrequently, melanocytic nevi undergo malignant transformation to melanoma. Understanding molecular and cellular mechanisms underlying oncogene-induced senes...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2016.08.001
更新日期：2017-01-01 00:00:00
abstract：:Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions, new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infanti...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/j.det.2010.03.005
更新日期：2010-07-01 00:00:00
abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2004.03.003
更新日期：2004-07-01 00:00:00
abstract：:The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet,...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2010.08.009
更新日期：2011-01-01 00:00:00
abstract：:Liposuction is the most popular cosmetic surgical procedure performed in men. Aside from traditional liposuction using the tumescent technique, several energy-assisted liposuction technologies have emerged and been proven safe and particularly beneficial for the male patient demographic. The differences in fat distrib...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2017.09.010
更新日期：2018-01-01 00:00:00
abstract：:Osteoporosis affects more than 75 million people in the United States, Asia, and Europe. Osteoporosis results from a combination of genetic and environmental factors that contribute to peak bone mass and the rate of bone loss. These factors include medications, diet, race, sex, lifestyle, and physical activity. The ma...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2006.01.013
更新日期：2006-04-01 00:00:00
abstract：:With simple, inexpensive therapy, virtually all venous ulcers heal without the need for hospitalization, skin grafting, growth factors, hyperbaric oxygen, or debilitating bed rest. Although the future promises to yield a greater understanding about the nature of these wounds and ways to treat them, one can benefit the...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：:The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radi...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2007.06.004
更新日期：2007-10-01 00:00:00
abstract：:Pemphigoid gestationis is a rare, autoimmune bullous disease of pregnancy that involves autoantibodies directed against type XVII collagen in the basement membrane zone. This article discusses the immunopathogenesis, diagnostic methods, and clinical features of this fascinating disease. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.03.002
更新日期：2011-07-01 00:00:00
abstract：:The development and use of various laser systems for the treatment of carcinomas of the skin constitute a relatively new therapeutic approach. Because the skin is a readily accessible organ, it is an excellent site at which to attempt different therapeutic modalities. What is truly astounding has been the development ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1991-10-01 00:00:00
abstract：:In this article, vulvar anatomy and histology are reviewed, and nonneoplastic and neoplastic epithelial disorders are presented. Included are lichen sclerosus, squamous cell hyperplasia, vulvar intraepithelial neoplasia, vulvar Paget's disease, and squamous cell carcinoma. Current terminology, tumor measurements, and ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1992-04-01 00:00:00
abstract：:Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutan...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.07.003
更新日期：2009-01-01 00:00:00
abstract：:Laser skin surgery is not without risk and some degree of downtime in most situations. Patient satisfaction is key to the perceived success of the procedure. Therefore, the physician must fully explain all risks, potential complications, and expected morbidity associated with any laser treatment to be performed. Altho...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(03)00054-8
更新日期：2002-01-01 00:00:00
abstract：:Sexual and gender minorities have unique risk factors that may increase their risk of developing skin cancer. In particular, sexual minority men report a higher prevalence of skin cancer (including both keratinocytes carcinomas and melanoma), higher rates of indoor tanning, and overall poorer sun protection behaviors....
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2019.10.005
更新日期：2020-04-01 00:00:00
abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.01.002
更新日期：2011-04-01 00:00:00
abstract：:Medical spas are the fasting growing segment of the 15-billion dollar spa industry. Although medical spas have been in existence since ancient times to treat a wide variety of ailments such as gout, arthritis, and diabetes, our modern concept of the medical spa combines relaxation with medical rejuvenative procedures....
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2008.03.003
更新日期：2008-07-01 00:00:00
abstract：:As with other chemical-based industries, the pharmaceutical industry has the potential for innumerable irritants and allergens. Prompt reporting and recognition of employees' skin diseases, with clarification of the triggering factors, can lead to appropriate control and prevention in many situations. ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1994-07-01 00:00:00
abstract：:Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/j.det.2011.03.015
更新日期：2011-07-01 00:00:00
abstract：:Hair transplantation has developed into a refined art in the past 30 years. Refined techniques and instruments, appreciation of properly placed hairlines, better methods of harvesting donor grafts, and better cutting materials in punches have significantly improved results in one of the most frequently performed cosme...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：
更新日期：1987-07-01 00:00:00
abstract：:Colored cosmetics are an important part of the dermatologic armamentarium. They can camouflage contour and pigment abnormalities, provide moisturization, enhance oil control, add sun protection, deliver barrier-enhancing agents, increase acne treatment, and create a sense of personal well-being. Familiarity with these...
journal_title：Dermatologic clinics
pub_type： 杂志文章
doi：10.1016/s0733-8635(05)70213-8
更新日期：2000-10-01 00:00:00
abstract：:KS remains a challenge to clinicians and investigators more than a century after its initial description. Debate continues as to the cell of origin, as well as whether or not it is a true cancer. KS appears to be an opportunistic neoplasm, which in its earliest phase retains some features of a benign hyperproliferativ...
journal_title：Dermatologic clinics
pub_type： 杂志文章,评审
doi：10.1016/s0733-8635(05)70424-1
更新日期：1997-01-01 00:00:00
