Abstract:
:Extramammary Paget disease is an intraepidermal adenocarcinoma, most often limited to the epidermis, with typical cases affecting genital skin. When limited to the epidermis, primary extramammary Paget disease is not life-threatening, but invasive disease may portend a poor prognosis. Surgical excision remains the mainstay of treatment of extramammary Paget disease, and Mohs micrographic surgery is the surgical treatment of choice. Alternative treatments include topical 5-fluorouracil and imiquimod, photodynamic therapy, laser vaporization, chemotherapy, and radiation therapy but data are limited. Implementation of cytokeratin 7 immunostain has increased the ability to detect extramammary Paget disease on frozen section.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Merritt BG,Degesys CA,Brodland DGdoi
10.1016/j.det.2019.02.002subject
Has Abstractpub_date
2019-07-01 00:00:00pages
261-267issue
3eissn
0733-8635issn
1558-0520pii
S0733-8635(19)30013-0journal_volume
37pub_type
杂志文章,评审abstract::The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...
journal_title:Dermatologic clinics
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doi:10.1016/j.det.2004.03.003
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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pub_type: 杂志文章,评审
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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journal_title:Dermatologic clinics
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