Abstract:
:The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radiation-exposed skin and metabolically converted to the active metabolite, 1alpha,25-dihydroxyvitamin D(3). This nuclear hormone binds with high affinity the nuclear receptor vitamin D receptor. More than 3000 synthetic analogs of 1alpha,25(OH)(2)D(3) are known. This review aims to provide an overview on vitamin D signaling from the skin perspective.
journal_name
Dermatol Clinjournal_title
Dermatologic clinicsauthors
Carlberg C,Seuter Sdoi
10.1016/j.det.2007.06.004subject
Has Abstractpub_date
2007-10-01 00:00:00pages
515-23, viiiissue
4eissn
0733-8635issn
1558-0520pii
S0733-8635(07)00062-9journal_volume
25pub_type
杂志文章,评审abstract::Epidermolysis bullosa (EB) in Mexico continues to be a rare genodermatosis that is still unknown for most of the health care professionals in the country. The spirit of DebRA MEXICO was born in 1994 when the Mexican health care team started to see patients with the main purpose to provide medical care, genetic counsel...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.02.014
更新日期:2010-04-01 00:00:00
abstract::This article is a tribute to clinician Henry M. Lewis. The author shares practical therapeutic pearls developed and used over the years by Dr. Lewis. ...
journal_title:Dermatologic clinics
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Oral health is a critical component of overall health and well-being. Dental caries and periodontitis are two of the most common oral diseases and, when not treated, can have irreversible sequelae and overall psychosocial and physiologic impact on individuals, diminishing quality of life. The burden of advanced dental...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2020.05.002
更新日期:2020-10-01 00:00:00
abstract::Patients who present with concerns that they suffer from sexually transmitted infection frequently suffer from other problems. Occasionally it is simply not enough just to demonstrate that the patient has no evidence of sexually transmitted disease, but it is important to diagnose the cause of their symptoms and to re...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70046-2
更新日期:1998-10-01 00:00:00
abstract::A discussion of the pathologic findings found with aging and photodamage is used to formulate a rational preoperative regimen, treatment technique, and maintenance regimen. Details of laser treatment technique, anesthesia, and postoperative care are given. Possible contraindications are discussed, as are the pros and ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70452-6
更新日期:1997-07-01 00:00:00
abstract::Colored cosmetics are an important part of the dermatologic armamentarium. They can camouflage contour and pigment abnormalities, provide moisturization, enhance oil control, add sun protection, deliver barrier-enhancing agents, increase acne treatment, and create a sense of personal well-being. Familiarity with these...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70213-8
更新日期:2000-10-01 00:00:00
abstract::Reconstruction of the nose provides many challenges owing to its differing subunits and varied surfaces. In this article, the nasal anatomy, anesthesia, and some of the reconstructive options available to the dermatologic surgeon are reviewed. These reconstructive options are based on the subunit and depth of the defe...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70489-7
更新日期:1998-01-01 00:00:00
abstract::The varied histopathology of the reactive inflammatory vascular dermatoses requires close cooperation between the clinician and the pathologist. This article presents an overview of the histology of this group of dermatoses, including the figurate erythemas, the pigmented purpuric eruptions, urticaria and urticarial v...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::A compendium of uncommon dermatologic treatments, both medical and surgical, are presented. This article is based on a survey of the members of the Noah Worcester Dermatologic Society with subsequent additions, including treatment pearls from the Internet and other contributions from practicing dermatologists, as well...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70179-0
更新日期:2000-04-01 00:00:00
abstract::This article describes major screening studies of the past two decades, discusses the evidence-based screening recommendations, highlights the need to screen high-risk and previously unscreened populations, and concludes with suggestions for risk assessment and physician-nurse training in the skin cancer examination. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(02)00034-7
更新日期:2002-10-01 00:00:00
abstract::The Israeli population is characterized by unique demographic features including high genetic homogeneity within many closed communities. As a consequence the molecular epidemiology of epidermolysis bullosa differs markedly in this country and surrounding areas from that reported in the Western world. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2010.02.019
更新日期:2010-04-01 00:00:00
abstract::Dermatopathology (DP) education is critical to the comprehensive training of dermatology and pathology residents and to the accurate diagnosis and management of cutaneous disease. DP has seen tremendous growth, and its success depends on our ability to effectively educate future leaders, teachers, and researchers who ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.06.003
更新日期:2012-10-01 00:00:00
abstract::This article reviews the recent dermatopathology literature involving nonmelanocytic neoplasia, with a focus on important work done over the last 5 years. The discussion includes advances in the understanding of Merkel cell carcinoma pathogenesis and prognosis; changes in the seventh edition of the American Joint Comm...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2012.06.009
更新日期:2012-10-01 00:00:00
abstract::Discolorations of the skin, such as vitiligo, were recognized thousands of years ago. White spots caused by vitiligo and other disorders have caused significant social opprobrium to those disfigured by these pigmentary disorders, throughout history and still in the present day. Treatments have been desperately sought ...
journal_title:Dermatologic clinics
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.det.2016.11.001
更新日期:2017-04-01 00:00:00
abstract::Medical spas are the fasting growing segment of the 15-billion dollar spa industry. Although medical spas have been in existence since ancient times to treat a wide variety of ailments such as gout, arthritis, and diabetes, our modern concept of the medical spa combines relaxation with medical rejuvenative procedures....
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2008.03.003
更新日期:2008-07-01 00:00:00
abstract::The general goals of medical management of vitiligo are to repigment vitiliginous areas of skin and to stabilize the progression of depigmentation. However, for some patients with vitiligo affecting extensive body surface areas who are unresponsive to repigmentation therapies, depigmentation of the remaining normal sk...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.11.010
更新日期:2017-04-01 00:00:00
abstract::Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.01.012
更新日期:2007-04-01 00:00:00
abstract::The recent progress made in understanding the normal biology and biochemistry of the extracellular matrix of human skin has allowed us to identify several different levels at which errors could be introduced into the structure and metabolism of collagen or elastin, the two major fibrillar components of the dermis. Cur...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1987-01-01 00:00:00
abstract::Chronic telogen effluvium is not uncommon. It is a form of diffuse hair loss affecting the entire scalp for which no obvious cause can be found. It usually affects women of 30 to 60 years of age who generally have a full head of hair prior to the onset of shedding. The onset is usually abrupt, with or without a recogn...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70398-3
更新日期:1996-10-01 00:00:00
abstract::Large defects may at first appear to be too big to close in a side-to-side fashion. Certain wounds and situations may call for healing with second intent. Undermining and pulley sutures are very helpful in bringing together wound edges of certain large openings. Partial closures may decrease the tendency to exert unwa...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70294-1
更新日期:2001-07-01 00:00:00
abstract::This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2007.01.008
更新日期:2007-04-01 00:00:00
abstract::Though history will mark June 1981 as the birthday of the AIDS pandemic, the first true case of the syndrome and its cause originated years before in West-Central Africa. History also highlights the irony that the discovery of AIDS, the detection of its cause, and the development of drugs for its treatment, all occurr...
journal_title:Dermatologic clinics
pub_type: 历史文章,杂志文章
doi:10.1016/j.det.2006.05.001
更新日期:2006-10-01 00:00:00
abstract::Nasal reconstruction can be challenging due to the complex nature of multiple cosmetic units and functional considerations. This article discusses single- and two-staged melolabial flap repairs for nasal reconstruction following removal of skin cancers. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2004.08.003
更新日期:2005-01-01 00:00:00
abstract::Human herpesviruses and human papillomaviruses are ubiquitous and may cause an array of oral disease. Herpesviruses are unique because recurrent localized disease occurs after the primary infection. Human papillomaviruses are known for their ability to produce benign epithelial proliferations and increasingly are impl...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70352-1
更新日期:1996-04-01 00:00:00
abstract::Although trichoscopy has only recently been introduced in the assessment of hair and scalp disorders, it is already considered an essential diagnostic tool by many experts in the field. This article discusses topics that are often a source of doubt among clinicians, and tips that may help dermatologists better perform...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2018.05.008
更新日期:2018-10-01 00:00:00
abstract::Melanocytic nevi represent benign clonal proliferations of the melanocytes in the skin that usually remain stable in size and behavior or disappear during life. Infrequently, melanocytic nevi undergo malignant transformation to melanoma. Understanding molecular and cellular mechanisms underlying oncogene-induced senes...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/j.det.2016.08.001
更新日期:2017-01-01 00:00:00
abstract::This article contains a potpurri of surgically related stratagems, alternative techniques, and philosophies. These surgical pearls have been selected for their simplicity, usefulness, and applicability. ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
abstract::The diagnosis of lymphoma currently relies on a combination of clinical, routine histopathologic, and immunohistochemical studies, sometimes supplemented by other special techniques such as flow cytometry, DNA analysis, and gene rearrangement study. This review considers the practical diagnosis of cutaneous lymphoma, ...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Liposuction of arms when properly performed with realistic expectations is almost always a "patient pleaser." Patients routinely marvel at the degree of skin contraction that typically occurs. Before and after photos, even as early as 1 week, routinely show dramatic skin contraction when significant volumes of fat are...
journal_title:Dermatologic clinics
pub_type: 杂志文章
doi:10.1016/s0733-8635(05)70127-3
更新日期:1999-10-01 00:00:00
abstract::Stress is an abnormal or extreme adjustment in the physiology of an animal to cope with adverse effects of its environment and management. The adverse effect is designated the stressor. In this article, the authors try to focus on the main types of host factors that can influence stress (genetics, perception) and on t...
journal_title:Dermatologic clinics
pub_type: 杂志文章,评审
doi:10.1016/s0733-8635(05)70368-5
更新日期:1996-07-01 00:00:00